Upstate South Carolina Mountain Vacations 2026

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Top Mountain Upstate South Carolina Hotels

Drury Inn & Suites Greenville

10 Carolina Point Pkwy Greenville SC

2 hours drive from Clemson University

Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

9.4/10 Exceptional! (1,082 reviews)

"Unfortunately construction was in progress, very noisy. I wish I had known I would have chosen another hotel"

Reviewed on Sep 29, 2026

The Westin Poinsett Greenville

120 South Main St Greenville SC

1 hour drive from Clemson University

Book a stay at this business-friendly hotel in Greenville. Enjoy breakfast (surcharge), a free airport shuttle, and 24-hour room service. Our guests praise the ...

Hampton Inn Gaffney

115 Nancy Creek Rd Gaffney SC

3 hours drive from Clemson University

Stay at this hotel in Gaffney. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Gaffney ...

8.8/10 Excellent! (771 reviews)

"Great hotel for an overnight stay. We were pleasantly surprised how nice this place was. Quiet, clean, comfy beds and a great breakfast with more options than normal for the included ones. Would definitely recommend this for a clean quiet place to stay while visiting the National Battlefields!"

Reviewed on Sep 24, 2026

See all 3,083 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.