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Top Adults Only Gulf Coast Hotels

Shoreline Island Resort - Exclusively Adult

14200 Gulf Boulevard Madeira Beach FL

59 min drive from Port of Tampa

Book a stay at this beach aparthotel in Madeira Beach. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the helpful staff in our reviews. ...

9.2/10 Wonderful! (1,444 reviews)

Room was spotless bedding was exceptional The staff is wonderful this is our 3rd time at the shoreline

Reviewed on Jan 8, 2026

The Southernmost Inn - Adults Only

525 United Street Key West FL

9 hours drive from Port of Tampa

Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...

8.2/10 Very Good! (1,246 reviews)

Property needs some serious maintenance. One guest cut their foot on a broken tile in the hot tub. They are working on painting the outside but let it go a little longer than they should have. The rooms shown on Expedia make them look much larger than they actually are. Bathroom was exceptionally ...

Reviewed on Jan 16, 2026

Upper Deck Hotel and Bar - Adults Only

120 E Atol St. South Padre Island TX

Stay at this hotel in South Padre Island. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions ...

9.2/10 Wonderful! (171 reviews)

Great entertainment!

Reviewed on Dec 28, 2025

See all 182,949 properties in Gulf Coast

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.