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Top Adults Only Florida Keys Hotels

The Southernmost Inn - Adults Only

525 United Street Key West FL

9 min walk from Duval Street

Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...

8.4/10 Very Good! (1,361 reviews)

"Great experience"

Reviewed on May 18, 2026

Paradise Inn Key West - Adults Only

819 Simonton Street Key West FL

4 min walk from Duval Street

Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, parking (surcharge), and a garden. Our guests praise the breakfast and the pool ...

9.2/10 Wonderful! (1,009 reviews)

"Everything was perfect."

Reviewed on May 18, 2026

Heron House - Adult Only

512 Simonton St Key West FL

3 min walk from Duval Street

Stay at this B&B in Key West. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the pool in our reviews. Popular attractions ...

9.2/10 Wonderful! (1,150 reviews)

"We moved from a tropical king to a king suite. This room did not have any seating however, our room faced the pool which I loved and enjoyed. The suite was larger with seating inside and on the porch. Will definitely come back. A shout out to Greg and Larry for their great hospitality!"

Reviewed on May 17, 2026

See all 8,335 properties in Florida Keys

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.