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Top Adults Only Florida Keys Hotels

The Southernmost Inn - Adults Only

525 United Street Key West FL

9 min walk from Duval Street

Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...

8.2/10 Very Good! (1,285 reviews)

Tanesha at the feont desk was absolutley increbible. I stayes in quite a few places in Key West and this was by fae my favorite. But a huge shour out to her for being so kind and patient. Amazing experience!!!

Reviewed on Mar 28, 2026

Paradise Inn Key West - Adults Only

819 Simonton Street Key West FL

4 min walk from Duval Street

Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, parking (surcharge), and daily housekeeping. Our guests praise the breakfast and ...

9.2/10 Wonderful! (1,001 reviews)

Wonderful property. Great location. Feels quiet and secluded. We loved the breakfast and the happy hour.

Reviewed on Mar 28, 2026

Heron House - Adult Only

512 Simonton St Key West FL

3 min walk from Duval Street

Stay at this B&B in Key West. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the pool in our reviews. Popular attractions ...

9/10 Wonderful! (1,127 reviews)

Breakfast was very good. Staff was excellent and quick to help with anything we needed. Property and room both needed maintenance. Bed wasn’t comfortably.

Reviewed on Mar 27, 2026

See all 8,317 properties in Florida Keys

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.