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Jan 15 - Jan 16
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Jan 16 - Jan 18
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Our top choices for Seneca hotels

Aerial view

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,000 reviews)
"Great place to stay. "
United States
Gene
The price is ￥17,271
￥21,440 total
includes taxes & fees
Jan 16 - Jan 17
Lakeside Lodge Clemson
Standard Room, 1 King Bed, Non Smoking, Jetted Tub | Desk, laptop workspace, blackout drapes, iron/ironing board

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very Good, (645 reviews)
"The stay was amazing "
United States
Tabatha
The price is ￥14,680
￥16,148 total
includes taxes & fees
Jan 26 - Jan 27
Best Western Seneca-Clemson
Terrace/patio

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (803 reviews)
"Perfect stay for a weekend. Lots of shopping and restaurants nearby. Clean safe area annd the staff was wonderful!"
United States
Cindy
The price is ￥16,710
￥18,382 total
includes taxes & fees
Jan 25 - Jan 26
Tru by Hilton Seneca Clemson
Reception

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (670 reviews)
"Great place to stay"
United States
Jose
The price is ￥18,894
￥20,785 total
includes taxes & fees
Jan 18 - Jan 19
Hampton Inn & Suites Seneca-Clemson Area
Property amenity

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 star property
Seneca
9.4 out of 10, Exceptional, (206 reviews)
"Spotless, friendly staff, great location. "
United States
Cari
The price is ￥19,806
￥21,787 total
includes taxes & fees
Jan 20 - Jan 21
Fairfield Inn & Suites Seneca Clemson Univ Area
Free daily on-the-go breakfast

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Seneca
8.0 out of 10, Very Good, (668 reviews)
"Good available parking. Room clean. Breakfast was minimal, but good. The tub was slippery and needed a mat. I almost fell a couple of times. I would stay here again."
United States
Denise
The price is ￥12,036
￥14,198 total
includes taxes & fees
Jan 25 - Jan 26
Quality Inn Seneca Clemson Area US-123
Free daily on-the-go breakfast

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (724 reviews)
"Room was clean. Quiet place to rest. Lisa at the front desk was very helpful and very nice. "
United States
Teresa
The price is ￥11,096
￥12,206 total
includes taxes & fees
Jan 18 - Jan 19
Days Inn by Wyndham Seneca / Clemson Area
Free breakfast

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very Good, (1,001 reviews)
"Easy check-in, friendly staff."
United States
Sharon
The price is ￥14,680
￥16,296 total
includes taxes & fees
Jan 20 - Jan 21
Best Western Plus Clemson Hotel & Conference Center
Free breakfast

Hampton Inn Anderson/ Alliance Business Park

Hampton Inn Anderson/ Alliance Business Park
2.5 star property
Anderson
9.2 out of 10, Wonderful, (815 reviews)
"Staff, Just a Nice Hotel"
United States
Christopher
The price is ￥17,290
￥19,192 total
includes taxes & fees
Jan 25 - Jan 26
Hampton Inn Anderson/ Alliance Business Park
Lobby

Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson
2.0 star property
Anderson
8.2 out of 10, Very Good, (1,001 reviews)
"Room was clean, front desk people were very nice. "
United States
Caressa
The price is ￥11,987
￥13,306 total
includes taxes & fees
Jan 18 - Jan 19
Microtel Inn & Suites by Wyndham Anderson/Clemson
Lobby

Holiday Inn Express Anderson by IHG

Holiday Inn Express Anderson by IHG
2.5 star property
Anderson
8.6 out of 10, Excellent, (385 reviews)
"Convenient location to I-85, quiet with nice parking area "
United States
Nancy
The price is ￥16,637
￥18,467 total
includes taxes & fees
Feb 1 - Feb 2
Holiday Inn Express Anderson by IHG
Lobby

Comfort Suites Anderson-Clemson

Comfort Suites Anderson-Clemson
2.5 star property
Anderson
8.4 out of 10, Very Good, (1,001 reviews)
"Everything was Great very friendly people "
United States
jose
The price is ￥15,618
￥17,335 total
includes taxes & fees
Jan 18 - Jan 19
Comfort Suites Anderson-Clemson
Lobby

Country Inn & Suites by Radisson, Anderson, SC

Country Inn & Suites by Radisson, Anderson, SC
2.5 star property
Anderson
8.4 out of 10, Very Good, (1,000 reviews)
"Everything was clean and breakfast was a nice spread. "
United States
Sheri
The price is ￥18,396
￥20,419 total
includes taxes & fees
Jan 22 - Jan 23
Country Inn & Suites by Radisson, Anderson, SC
Lobby

Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
3.0 star property
Anderson
9.0 out of 10, Wonderful, (691 reviews)
"Rooms were clean, staff were friendly, and we had 2 good night’s sleep."
United States
Sadie
The price is ￥16,761
￥18,603 total
includes taxes & fees
Jan 22 - Jan 23
Hilton Garden Inn Anderson
Studio Suite, 1 King Bed, Non Smoking | Jetted tub

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson
2.0 star property
Anderson
7.8 out of 10, Good, (1,001 reviews)
"Very nice we'll stay there again"
United States
Michael
The price is ￥9,967
￥11,064 total
includes taxes & fees
Jan 20 - Jan 21
Days Inn by Wyndham Anderson
Lobby

Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville
2.5 star property
Easley
7.4 out of 10, Good, (764 reviews)
"Easy access from the highway lot of restaurants around the hotel and staff is very friendly"
United States
brian
The price is ￥10,695
￥11,872 total
includes taxes & fees
Jan 17 - Jan 18
Baymont by Wyndham Easley/Greenville
Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency) | Premium bedding, individually decorated, desk, laptop workspace

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.2 out of 10, Very Good, (1,000 reviews)
"Clean and convenient "
United States
Olga
The price is ￥15,972
￥17,729 total
includes taxes & fees
Jan 28 - Jan 29
Comfort Inn & Suites Clemson - University Area
Lobby

Quality Inn Clemson near University

Quality Inn Clemson near University
2.5 star property
Anderson
7.0 out of 10, Good, (894 reviews)
"Bueno was "
Mexico
Alejandro
The price is ￥7,327
￥8,134 total
includes taxes & fees
Jan 22 - Jan 23
Quality Inn Clemson near University
Hallway

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
Clemson
9.8 out of 10, Exceptional, (791 reviews)
"Clean room, great location, wonderful staff!"
United States
Joyce
The price is ￥23,609
￥26,205 total
includes taxes & fees
Jan 20 - Jan 21
The Inn at Patrick Square
Lobby lounge

Inn @ Clemson

Inn @ Clemson
2.5 star property
Clemson
8.0 out of 10, Very Good, (1,008 reviews)
"Staff and hotel was amazing "
United States
Keren
Inn @ Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Seneca

Find the best Seneca areas and neighborhoods for the activities you enjoy most.

Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.

Downtown

While visiting Downtown, you might make a stop by sights like Seneca Historic District and Oconee County Library Seneca Branch.

Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, South Beach and Lake Keowee are some notable places to visit nearby.

Indian Oaks

While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like Oconee County Library Seneca Branch and Seneca Historic District.

Keowee Plantation

When in Keowee Plantation, you can plan a visit to Oconee County Library Seneca Branch and Seneca Historic District, some noteworthy sights in the nearby area.

Stay near popular Seneca attractions

High Shoals Falls in South Mountains State Park

High Falls County Park

Nestled along Lake Keowee with the Blue Ridge Mountains as backdrop, High Falls County Park offers pristine swimming and camping spots. Reserve waterfront campsites early to enjoy the park's serene natural setting.
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Lovely shot of the Blue Ridge Mountains in the distance, with a rural pasture in the foreground, in late summer when the grass is starting to turn yellow and brown. Upstate South Carolina scene.

Blue Ridge Field

This historic park honors African-American education in Oconee County on the former Blue Ridge High School football grounds. Stroll the paved loop trail and explore community gardens in this peaceful green space.
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Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

See all hotels in Seneca
Lake Keowee South Carolina

Top Seneca Hotel Reviews

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

10/10 Excellent
"Excellent stay."
Beonca 1-night trip
Posted 3 weeks ago
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

More cheap stays in Seneca

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

1007 George Smith Mill Rd Anderson SC
The price is ￥9,967 per night from Jan 20 to Jan 21
￥9,967
￥11,064 total
Jan 20 - Jan 21
includes taxes & fees
7.8/10 Good! (1,001 reviews)

Frequently asked questions

Where is the best place for a stay in Seneca?
Tru by Hilton Seneca Clemson is ranked highly by Expedia customers. This hotel offers free breakfast and free parking. Traveler reviews also recommend Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.
What's the top vacation rental in Seneca?
Luxury 4BR/4BA Lake Keowee Retreat- Mountain Cabin Vibes + Private Dock: Visitors give good reviews to this Seneca vacation home rental, which is located on a lake and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms and a kitchen with a dishwasher. Some other homes for rent in Seneca include Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub and 5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!. See all vacation rentals in Seneca.
If I need to cancel my hotel reservation in Seneca, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.
Where can I learn more about changing or cancelling my trip to Seneca?
To find more details about updating your trip to Seneca or cancelling it, click here.
What's the best place to stay for a family vacation to Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Attractions in the area like Ultimate Action Sports are also fun for the whole family. Find more child-friendly accommodations in Seneca.
What's the best LGBTQ-friendly place to stay in Seneca?
Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Tru by Hilton Seneca Clemson is another good choice for your stay. See all available hotels listed as LGBTQ-friendly in Seneca.
What's the best pet-friendly accommodation in Seneca?
Lakeside Lodge Clemson is a top hotel for people traveling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices to stay with your pet include Days Inn by Wyndham Seneca / Clemson Area and Tru by Hilton Seneca Clemson. See more pet-friendly hotel accommodations in Seneca.
What are some hotels with pools in Seneca?
Lakeside Lodge Clemson: Hotel located near Clemson University. Features free self parking, a seasonal outdoor pool, and complimentary wireless internet access. Quality Inn Seneca Clemson Area US-123 and Hampton Inn & Suites Seneca-Clemson Area are two additional hotels with an onsite pool. View all hotels with pools in Seneca.
What is the best accommodation for staying close to Greenville-Spartanburg International Airport (GSP)?
Wyndham Garden Greenville Airport is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and a restaurant. It's located 3.8 mi (6.1 km) from Greenville-Spartanburg Intl. Airport. Other good options near the airport include Best Western Greenville Airport Inn and Extended Stay America - Greenville - Airport.
What is staying in Seneca like?
Visitors to Seneca are sure to enjoy the sporting events, lakeside setting, and university setting. Welcoming and scenic, this city also attracts tourists with its coffeehouses. In Seneca, there are 290 hotels and other accommodations to choose from. Find out more about Seneca.
What should I do while I'm visiting Seneca?
Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Keowee Reservoir, Lake Keowee, and Lake Hartwell. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Check out what more to see and do in Expedia's Seneca guide.
What's the weather like in Seneca?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.

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