The Best Pet-friendly Hotels in Seneca, SC from ￥14,164 in 2026

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Our top choices for Seneca pet-friendly hotels

Desk, blackout drapes, iron/ironing board, WiFi (free)

1. Tru by Hilton Seneca Clemson

Seneca

Susana

￥16,934

￥18,627 total

includes taxes & fees

Sep 13 - Sep 14

Pillowtop beds, desk, laptop workspace, blackout drapes

2. Quality Inn Seneca US-123

Seneca

Anthony

￥12,017

￥14,175 total

includes taxes & fees

Aug 30 - Aug 31

3. Lakeside Lodge Clemson

Seneca

Laura

￥17,326

￥21,508 total

includes taxes & fees

Aug 23 - Aug 24

4. Days Inn by Wyndham Seneca / Clemson Area

Seneca

John

￥12,876

￥14,164 total

includes taxes & fees

Aug 27 - Aug 28

1 bedroom, desk, laptop workspace, bed sheets

5. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

Nirumol

￥14,782

￥23,253 total

includes taxes & fees

Sep 21 - Sep 22

Coffee/tea maker, fridge, microwave, oven

6. Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

Seneca

Josie G.

￥23,843

￥31,997 total

includes taxes & fees

Aug 26 - Aug 27

7. Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University

Seneca

Brenda

￥25,035

￥51,494 total

includes taxes & fees

Aug 23 - Aug 24

8. Iroquois Crossroads - 10 min from Clemson & lakes

Seneca

￥18,598

￥53,331 total

includes taxes & fees

Sep 8 - Sep 9

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Top Seneca Hotel Reviews

Days Inn by Wyndham Seneca / Clemson Area

8/10 Good

"Friendly staff, close to grocery, fast food, bank etc. close to lake keowee. Could have been cleaner,our feet were dirty just walking on the floor barefoot and trying to wipe water off the floor after coming in from the pool turned the towel brown, so the floors were definitely not getting mopped between guests. We were on ground level and came out after dark and the amount of spiders and spiderwebs kept us from walking out there the following night 😆 someone needs to take a broom around. But overall it was a reasonable price and place to stay. If it was cleaned/better maintained I wouldn't have had anything negative to say."

Quality Inn Seneca US-123

10/10 Excellent

"Persons at front desk and management"

Fall fun at the cabin! Convenient to Lake Keowee and Clemson

10/10 Excellent

"Great property I wish there was more lighting around the stairs and where you park at night think that would be helpful. Very clean."

Frequently asked questions

What's the best pet-friendly accommodation in Seneca?

Lakeside Lodge Clemson is a top hotel for people traveling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices to stay with your pet include Tru by Hilton Seneca Clemson and Quality Inn Seneca US-123.

How many hotels that accept pets should I expect to find in Seneca?

Stay with your furry friend at one of Expedia's 5 pet-friendly Seneca hotels or accommodations.

What's the best time of year to travel to Seneca with my pet?

When you're traveling with pets, keeping track of the weather can help you make the trip more safe and fun for everyone. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.

What is there to see and do with your pet in Seneca?

Known for its sports, Seneca has lots to offer visitors including its university life and waterfront. See the local sights and visit Oconee County Library Seneca Branch and Lake Keowee. While you're there, make sure you don't miss Keowee Key Golf Course and Lake Hartwell.

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Check availability on Seneca Pet-friendly Hotels

Our top choices for Seneca pet-friendly hotels

1. Tru by Hilton Seneca Clemson

2. Quality Inn Seneca US-123

3. Lakeside Lodge Clemson

4. Days Inn by Wyndham Seneca / Clemson Area

5. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

6. Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

7. Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University

8. Iroquois Crossroads - 10 min from Clemson & lakes

9. Carolina Cottage Retreat-12 Minutes from Clemson University

10. 3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

Top Seneca Hotel Reviews

Days Inn by Wyndham Seneca / Clemson Area

Quality Inn Seneca US-123

Fall fun at the cabin! Convenient to Lake Keowee and Clemson

Frequently asked questions

Explore a world of travel with Expedia

Find Pet-friendly Hotels in Seneca, SC

Change your mind

Treat yourself

Be picky

Check availability on Seneca Pet-friendly Hotels

Our top choices for Seneca pet-friendly hotels

1. Tru by Hilton Seneca Clemson

2. Quality Inn Seneca US-123

3. Lakeside Lodge Clemson

4. Days Inn by Wyndham Seneca / Clemson Area

5. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

6. Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

7. Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University

8. Iroquois Crossroads - 10 min from Clemson & lakes

9. Carolina Cottage Retreat-12 Minutes from Clemson University

10. 3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

Top Seneca Hotel Reviews

Days Inn by Wyndham Seneca / Clemson Area

Quality Inn Seneca US-123

Fall fun at the cabin! Convenient to Lake Keowee and Clemson

Frequently asked questions

Explore a world of travel with Expedia