Lake Keowee South Carolina

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Our top choices for Seneca hotels

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,013 reviews)
"I enjoyed my stay and all the amenities were excellent! I can’t wait to return!"
United States
Renata
The price is ¥17,466
¥21,682 total
includes taxes & fees
Jun 15 - Jun 16
Lakeside Lodge Clemson

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
Seneca
9.4 out of 10, Exceptional, (235 reviews)
"Excellent in every way … staff, room, amenities and very comfortable bed!"
United States
Sarah
The price is ¥19,224
¥21,147 total
includes taxes & fees
Jun 18 - Jun 19
Fairfield Inn & Suites Seneca Clemson Univ Area

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very Good, (713 reviews)
"Clean room comfortable beds"
United States
Cheryl
The price is ¥13,548
¥15,912 total
includes taxes & fees
Jun 21 - Jun 22
Quality Inn Seneca Clemson Area US-123

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (752 reviews)
"Clean and comfortable "
United States
Robyn
The price is ¥11,986
¥13,184 total
includes taxes & fees
Jun 18 - Jun 19
Days Inn by Wyndham Seneca / Clemson Area

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (845 reviews)
"Everything about this hotel was great the staff was very friendly rooms was very clean great location I highly suggest staying here"
United States
Jason
The price is ¥16,926
¥18,618 total
includes taxes & fees
Jul 3 - Jul 4
Tru by Hilton Seneca Clemson

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very Good, (664 reviews)
"Friendly staff, comfortable bed"
United States
Michelle
The price is ¥15,507
¥17,059 total
includes taxes & fees
Jun 18 - Jun 19
Best Western Seneca-Clemson

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (722 reviews)
"Nice staff, clean rooms, nice breakfast "
United States
Daren
The price is ¥19,017
¥20,917 total
includes taxes & fees
Jun 21 - Jun 22
Hampton Inn & Suites Seneca-Clemson Area

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (78 reviews)
"Awesome place "
United States
Jason
The price is ¥17,466
¥26,264 total
includes taxes & fees
Jun 21 - Jun 22
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
Anderson
9.2 out of 10, Wonderful, (624 reviews)
"Room was clean and customer service was excellent, check in was smooth "
United States
Gina
The price is ¥17,626
¥19,565 total
includes taxes & fees
Jun 20 - Jun 21
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Hampton Inn Hartwell

Hampton Inn Hartwell
2.5 star property
Hartwell
9.0 out of 10, Wonderful, (373 reviews)
"Nice hotel for the area. "
United States
Judith
The price is ¥18,358
¥21,911 total
includes taxes & fees
Jul 12 - Jul 13
Hampton Inn Hartwell

Home2 Suites by Hilton Anderson Downtown

Home2 Suites by Hilton Anderson Downtown
3.0 star property
Anderson
9.4 out of 10, Exceptional, (244 reviews)
"Clean, great location with easy access. Great staff and affordable."
United States
Ronald
The price is ¥22,421
¥24,888 total
includes taxes & fees
Jul 12 - Jul 13
Home2 Suites by Hilton Anderson Downtown

Hampton Inn Anderson/ Alliance Business Park

Hampton Inn Anderson/ Alliance Business Park
2.5 star property
Anderson
9.2 out of 10, Wonderful, (849 reviews)
"This place is always clean and staff is so kind and helpful"
United States
Osiry
The price is ¥18,190
¥20,191 total
includes taxes & fees
Jun 21 - Jun 22
Hampton Inn Anderson/ Alliance Business Park

Super 8 by Wyndham Anderson/Clemson Area

Super 8 by Wyndham Anderson/Clemson Area
2.5 star property
Anderson
6.6 out of 10, (292 reviews)
"I completely enjoyed my stay"
United States
Mia
The price is ¥10,881
¥12,078 total
includes taxes & fees
Jun 22 - Jun 23
Super 8 by Wyndham Anderson/Clemson Area

Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville
2.5 star property
Easley
7.4 out of 10, Good, (830 reviews)
"I loved my stay. one of my first hotels I've stayed at, and it was a great experience."
United States
Samantha
The price is ¥12,338
¥13,696 total
includes taxes & fees
Jun 14 - Jun 15
Baymont by Wyndham Easley/Greenville

Carolina Inn Anderson Clemson Area

Carolina Inn Anderson Clemson Area
2.5 star property
Anderson
8.4 out of 10, Very Good, (5 reviews)
"The staff is great "
United States
Luis Fernando
The price is ¥8,813
¥9,782 total
includes taxes & fees
Jun 15 - Jun 16
Carolina Inn Anderson Clemson Area

Quality Inn & Suites Easley - Greenville

Quality Inn & Suites Easley - Greenville
2.5 star property
Easley
7.0 out of 10, Good, (464 reviews)
"The manager was great. Room quality for value was also great."
United States
Jennifer
The price is ¥10,599
¥11,765 total
includes taxes & fees
Jul 12 - Jul 13
Quality Inn & Suites Easley - Greenville

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson
2.0 star property
Anderson
8.0 out of 10, Very Good, (1,017 reviews)
"Everything about the place was great"
United States
Eli
The price is ¥10,473
¥11,625 total
includes taxes & fees
Jul 12 - Jul 13
Days Inn by Wyndham Anderson

Quality Inn Clemson near University

Quality Inn Clemson near University
2.5 star property
Anderson
7.0 out of 10, Good, (940 reviews)
"Clean room,ac in the middle of a decent size town, overall good hotel"
United States
Roberto
The price is ¥9,132
¥10,137 total
includes taxes & fees
Jul 12 - Jul 13
Quality Inn Clemson near University

Holiday Inn Express Anderson by IHG

Holiday Inn Express Anderson by IHG
2.5 star property
Anderson
8.4 out of 10, Very Good, (399 reviews)
"The room was clean and comfortable with great AC. The hotel staff was very pleasant and helpful. I would definitely stay there again."
United States
Lawrence Edward
The price is ¥16,985
¥18,854 total
includes taxes & fees
Jul 11 - Jul 12
Holiday Inn Express Anderson by IHG

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very Good, (1,005 reviews)
"We always stay here when in Clemson. It's convenient and the breakfast and restaurant are great."
United States
Greg
The price is ¥15,255
¥16,931 total
includes taxes & fees
Jun 16 - Jun 17
Best Western Plus Clemson Hotel & Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Seneca

Find the best Seneca areas and neighborhoods for the activities you enjoy most.

Downtown

Downtown Seneca captures the essence of small-town Southern charm with its well-preserved railroad heritage and historic brick buildings. Tree-lined streets lead to charming shops and local eateries housed in structures dating back to the 1800s. Ram Cat Alley's colorful murals tell stories of local history while the old courthouse square hosts community gatherings. This walkable district offers a peaceful retreat from big city life. Visitors can browse antique stores for railroad memorabilia, sample authentic Southern comfort food, or explore the cultural exhibits at the Bertha Lee Strickland Museum. The nearby Lake Keowee provides outdoor recreation just minutes away.

Serenity Bay

Serenity Bay offers a peaceful retreat within Saxony Forest's coastal embrace. The quiet residential streets wind through mature trees, creating a tranquil atmosphere away from tourist crowds. Nature lovers can explore nearby Lake Keowee or enjoy the neighborhood's forest trails. The area perfectly balances woodland serenity with beach proximity. Visitors should plan for self-contained vacation rentals rather than hotels. While dining options are limited within the neighborhood, the natural surroundings provide ideal conditions for relaxation and outdoor recreation.

Pine Ridge Point

Lake Keowee's serene waters lap against the shores of Pine Ridge Point, a tranquil residential haven in Seneca. Private docks stretch into crystal-clear waters where boats gently bob. Towering pines create natural privacy between lakefront homes. Visitors enjoy peaceful mornings watching mist rise over the water. This neighborhood offers an authentic lakeside living experience without tourist crowds. Vacation rentals range from cozy cabins to luxury estates with private boat slips. Days revolve around swimming, fishing, and water sports on Lake Keowee. Nature trails wind through mature forests for hiking and birdwatching.

Indian Oaks

Indian Oaks offers a tranquil retreat in suburban Seneca where mature oak trees create natural canopies over peaceful residential streets. This family-oriented community provides an authentic glimpse into American suburban living without tourist crowds. Landscaped yards and community green spaces showcase South Carolina's native beauty. Visitors can enjoy quiet morning walks on spacious sidewalks while listening to birdsong. Lake Keowee lies just beyond the neighborhood boundaries for those seeking water activities. With minimal commercial presence, Indian Oaks delivers a genuinely restful experience away from urban bustle.

Stay near popular Seneca attractions

Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

Lake Keowee South Carolina

Top Seneca Hotel Reviews

More cheap stays in Seneca

Frequently asked questions

Where is the best place for a stay in Seneca?
Lakeside Lodge Clemson is one of the top choices for your stay based on our traveler data. This hotel is a short 7-minute walk from Lake Hartwell, and it offers a restaurant and free parking. Other good options for your trip include Quality Inn Seneca Clemson Area US-123 and Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy. See all available top hotels, or vacation rentals in Seneca.
What's the top vacation rental in Seneca?
Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water: Visitors give good reviews to this Seneca vacation home rental, which is located on a lake and has a fireplace, a patio, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. You can relax into your vacation with a garden and a selection of games. Some other homes for rent in Seneca include 4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly! and Waterfront 3br home on Lake Hartwell near Clemson. See all vacation rentals in Seneca.
If I need to cancel my hotel reservation in Seneca, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.
Where can I learn more about changing or cancelling my trip to Seneca?
To find more details about updating your trip to Seneca or cancelling it, click here.
What's the best place to stay for a family vacation to Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Attractions in the area like Ultimate Action Sports are also fun for the whole family. Find more child-friendly accommodations in Seneca.
What's the best LGBTQ-friendly place to stay in Seneca?
Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Tru by Hilton Seneca Clemson is another good choice for your stay. See all available hotels listed as LGBTQ-friendly in Seneca.
What's the best pet-friendly accommodation in Seneca?
Lakeside Lodge Clemson is a top hotel for people traveling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices to stay with your pet include Tru by Hilton Seneca Clemson and Quality Inn Seneca Clemson Area US-123. See more pet-friendly hotel accommodations in Seneca.
What are some hotels with pools in Seneca?
Lakeside Lodge Clemson: Hotel, 7-minute walk from Lake Hartwell. Features free self parking, a seasonal outdoor pool, and complimentary wireless internet access. Quality Inn Seneca Clemson Area US-123 and Fairfield Inn & Suites Seneca Clemson Univ Area are two additional hotels with an onsite pool. View all hotels with pools in Seneca.
What is the best accommodation for staying close to Greenville-Spartanburg International Airport (GSP)?
Wyndham Garden Greenville Airport is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and a restaurant. It's located 3.8 mi (6.1 km) from Greenville-Spartanburg Intl. Airport. Other good options near the airport include Best Western Greenville Airport Inn and Extended Stay America - Greenville - Airport.
What is staying in Seneca like?
Visitors to Seneca are sure to enjoy the sporting events, lakeside setting, and university setting. Welcoming and scenic, this city also attracts tourists with its coffeehouses. In Seneca, there are 305 hotels and other accommodations to choose from. Find out more about Seneca.
What should I do while I'm visiting Seneca?
Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Lake Keowee, Lake Hartwell, and Keowee Reservoir. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Check out what more to see and do in Expedia's Seneca guide.
What's the weather like in Seneca?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.

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