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Our top choices for Seneca hotels

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very Good, (687 reviews)
"Everting was good"
United States
Susan
The price is ¥12,438
¥14,655 total
includes taxes & fees
Mar 21 - Mar 22
Quality Inn Seneca Clemson Area US-123

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
Seneca
9.4 out of 10, Exceptional, (214 reviews)
"Hotel and room were super clean. Hotel is fairly new and it shows. Nice view of Lake Keowee. Breakfast was quite good & excellent coffee. Would definitely stay there again. "
United States
Matthew
The price is ¥19,966
¥21,964 total
includes taxes & fees
Mar 19 - Mar 20
Fairfield Inn & Suites Seneca Clemson Univ Area

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (66 reviews)
"Excellent stay."
United States
Beonca
The price is ¥12,619
¥20,909 total
includes taxes & fees
Mar 18 - Mar 19
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,001 reviews)
"Great place and location, great mattress, "
United States
Jeffrey
The price is ¥17,411
¥21,613 total
includes taxes & fees
Mar 17 - Mar 18
Lakeside Lodge Clemson

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (815 reviews)
"The hotel was very clean staff was amazing "
United States
Clifford
The price is ¥17,613
¥19,373 total
includes taxes & fees
Mar 23 - Mar 24
Tru by Hilton Seneca Clemson

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (685 reviews)
"Rooms good for the night. No issues with rooms"
United States
Sofia
The price is ¥20,120
¥22,130 total
includes taxes & fees
Mar 18 - Mar 19
Hampton Inn & Suites Seneca-Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (731 reviews)
"Very nice and helpful at the fronte desk. Nice room and very comfortable bed"
United States
Crystal
The price is ¥11,269
¥12,396 total
includes taxes & fees
Mar 23 - Mar 24
Days Inn by Wyndham Seneca / Clemson Area

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very Good, (652 reviews)
"Room was clean and staff was very efficient. "
United States
Judith
The price is ¥16,157
¥17,772 total
includes taxes & fees
Mar 22 - Mar 23
Best Western Seneca-Clemson

Hampton Inn Hartwell

Hampton Inn Hartwell
2.5 star property
Hartwell
9.0 out of 10, Wonderful, (362 reviews)
"Clean Good parking"
United States
Jade
The price is ¥14,636
¥17,630 total
includes taxes & fees
Mar 28 - Mar 29
Hampton Inn Hartwell

Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville
2.5 star property
Easley
7.4 out of 10, Good, (788 reviews)
"Spotless room, comfortable bed, friendly and attentive staff, breakfast was quite nice"
United States
Teresa
The price is ¥10,063
¥11,170 total
includes taxes & fees
Mar 21 - Mar 22
Baymont by Wyndham Easley/Greenville

Hampton Inn & Suites Lavonia

Hampton Inn & Suites Lavonia
2.5 star property
Lavonia
9.0 out of 10, Wonderful, (391 reviews)
"Room was clean and staff was very friendly."
United States
clay
The price is ¥20,944
¥24,884 total
includes taxes & fees
Mar 21 - Mar 22
Hampton Inn & Suites Lavonia

Home2 Suites by Hilton Anderson Downtown

Home2 Suites by Hilton Anderson Downtown
3.0 star property
Anderson
9.4 out of 10, Exceptional, (231 reviews)
"Room was great and the staff polite and helpful "
United States
Sheila D
The price is ¥22,349
¥24,809 total
includes taxes & fees
Mar 29 - Mar 30
Home2 Suites by Hilton Anderson Downtown

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very Good, (1,006 reviews)
"Good stay and breakfast"
United States
Jeff
The price is ¥15,845
¥17,586 total
includes taxes & fees
Mar 18 - Mar 19
Best Western Plus Clemson Hotel & Conference Center

Holiday Inn Express Anderson by IHG

Holiday Inn Express Anderson by IHG
2.5 star property
Anderson
8.6 out of 10, Excellent, (386 reviews)
"Nice"
United States
William
The price is ¥16,772
¥18,617 total
includes taxes & fees
Apr 9 - Apr 10
Holiday Inn Express Anderson by IHG

Quality Inn & Suites Easley - Greenville

Quality Inn & Suites Easley - Greenville
2.5 star property
Easley
7.0 out of 10, Good, (412 reviews)
"Clean room Friendly Staff"
United States
Andrina
The price is ¥8,306
¥9,220 total
includes taxes & fees
Mar 22 - Mar 23
Quality Inn & Suites Easley - Greenville

Inn @ Clemson

Inn @ Clemson
2.5 star property
Clemson
8.2 out of 10, Very Good, (1,002 reviews)
"Very clean room, helpful agents, good breakfast.,"
United States
Jane
The price is ¥12,524
¥13,903 total
includes taxes & fees
Mar 17 - Mar 18
Inn @ Clemson

Quality Inn Clemson near University

Quality Inn Clemson near University
2.5 star property
Anderson
7.0 out of 10, Good, (903 reviews)
"Staff was great and our beds were very comfortable!"
United States
Laurie
The price is ¥8,411
¥9,335 total
includes taxes & fees
Apr 5 - Apr 6
Quality Inn Clemson near University

Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
3.0 star property
Anderson
9.0 out of 10, Wonderful, (704 reviews)
"Rooms were clean, staff were friendly, and we had 2 good night’s sleep."
United States
Sadie
The price is ¥15,866
¥17,611 total
includes taxes & fees
Mar 29 - Mar 30
Hilton Garden Inn Anderson

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
Clemson
9.4 out of 10, Exceptional, (982 reviews)
"Excellent stay "
United States
Elliott
The price is ¥23,800
¥26,418 total
includes taxes & fees
Mar 16 - Mar 17
Clemson University's James F. Martin Inn

Clemson Memorabilia House

Clemson Memorabilia House
3.0 star property
Clemson
9.8 out of 10, Exceptional, (9 reviews)
"We enjoyed our stay, it was the perfect size for our family of four. "
United States
Ashley
The price is ¥14,216
¥37,943 total
includes taxes & fees
Mar 16 - Mar 17
Clemson Memorabilia House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Seneca

Find the best Seneca areas and neighborhoods for the activities you enjoy most.

Downtown

Downtown Seneca captures the essence of small-town Southern charm with its well-preserved railroad heritage and historic brick buildings. Tree-lined streets lead to charming shops and local eateries housed in structures dating back to the 1800s. Ram Cat Alley's colorful murals tell stories of local history while the old courthouse square hosts community gatherings. This walkable district offers a peaceful retreat from big city life. Visitors can browse antique stores for railroad memorabilia, sample authentic Southern comfort food, or explore the cultural exhibits at the Bertha Lee Strickland Museum. The nearby Lake Keowee provides outdoor recreation just minutes away.

Serenity Bay

Serenity Bay offers a peaceful retreat within Saxony Forest's coastal embrace. The quiet residential streets wind through mature trees, creating a tranquil atmosphere away from tourist crowds. Nature lovers can explore nearby Lake Keowee or enjoy the neighborhood's forest trails. The area perfectly balances woodland serenity with beach proximity. Visitors should plan for self-contained vacation rentals rather than hotels. While dining options are limited within the neighborhood, the natural surroundings provide ideal conditions for relaxation and outdoor recreation.

Pine Ridge Point

Lake Keowee's serene waters lap against the shores of Pine Ridge Point, a tranquil residential haven in Seneca. Private docks stretch into crystal-clear waters where boats gently bob. Towering pines create natural privacy between lakefront homes. Visitors enjoy peaceful mornings watching mist rise over the water. This neighborhood offers an authentic lakeside living experience without tourist crowds. Vacation rentals range from cozy cabins to luxury estates with private boat slips. Days revolve around swimming, fishing, and water sports on Lake Keowee. Nature trails wind through mature forests for hiking and birdwatching.

Indian Oaks

Indian Oaks offers a tranquil retreat in suburban Seneca where mature oak trees create natural canopies over peaceful residential streets. This family-oriented community provides an authentic glimpse into American suburban living without tourist crowds. Landscaped yards and community green spaces showcase South Carolina's native beauty. Visitors can enjoy quiet morning walks on spacious sidewalks while listening to birdsong. Lake Keowee lies just beyond the neighborhood boundaries for those seeking water activities. With minimal commercial presence, Indian Oaks delivers a genuinely restful experience away from urban bustle.

Stay near popular Seneca attractions

Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

Lake Keowee South Carolina

Top Seneca Hotel Reviews

More cheap stays in Seneca

Frequently asked questions

Where is the best place for a stay in Seneca?
Tru by Hilton Seneca Clemson is ranked highly by Expedia customers. This hotel is a short 15-minute walk from Clemson University, and it offers free breakfast and free parking. Traveler reviews also recommend Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.
What's the top vacation rental in Seneca?
Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock: Visitors give good reviews to this Seneca vacation home rental, which is located on a lake and has a patio, a private yard, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. Some other homes for rent in Seneca include Lake House with Dock, Pool, and Pet Friendly. 8 Minutes from Clemson. and New to VRBO! Big water views, private dock, pool table, 15 min Clemson!. See all vacation rentals in Seneca.
If I need to cancel my hotel reservation in Seneca, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.
Where can I learn more about changing or cancelling my trip to Seneca?
To find more details about updating your trip to Seneca or cancelling it, click here.
What's the best place to stay for a family vacation to Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Attractions in the area like Ultimate Action Sports are also fun for the whole family. Find more child-friendly accommodations in Seneca.
What's the best LGBTQ-friendly place to stay in Seneca?
Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Tru by Hilton Seneca Clemson is another good choice for your stay. See all available hotels listed as LGBTQ-friendly in Seneca.
What's the best pet-friendly accommodation in Seneca?
Lakeside Lodge Clemson is a top hotel for people traveling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices to stay with your pet include Days Inn by Wyndham Seneca / Clemson Area and Tru by Hilton Seneca Clemson. See more pet-friendly hotel accommodations in Seneca.
What are some hotels with pools in Seneca?
Lakeside Lodge Clemson: Hotel located near Clemson University. Features free self parking, a seasonal outdoor pool, and complimentary wireless internet access. Hampton Inn & Suites Seneca-Clemson Area and Days Inn by Wyndham Seneca / Clemson Area are two additional hotels with an onsite pool. View all hotels with pools in Seneca.
What is the best accommodation for staying close to Greenville-Spartanburg International Airport (GSP)?
Wyndham Garden Greenville Airport is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and a restaurant. It's located 3.8 mi (6.1 km) from Greenville-Spartanburg Intl. Airport. Other good options near the airport include Best Western Greenville Airport Inn and Extended Stay America - Greenville - Airport.
What is staying in Seneca like?
Visitors to Seneca are sure to enjoy the sporting events, lakeside setting, and university setting. Welcoming and scenic, this city also attracts tourists with its coffeehouses. In Seneca, there are 299 hotels and other accommodations to choose from. Find out more about Seneca.
What should I do while I'm visiting Seneca?
Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Keowee Reservoir, Lake Keowee, and Lake Hartwell. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Check out what more to see and do in Expedia's Seneca guide.
What's the weather like in Seneca?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.

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