A calm lake with mountains in the background.

Seneca Vacation Rentals

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Check prices for these dates

In two weeks
Oct 30 - Nov 1
In two months
Dec 11 - Dec 13
In three months
Jan 8 - Jan 10
In four months
Feb 5 - Feb 7

Our top choices for Seneca vacation rentals

A cabin with a cozy interior, a wooden exterior, and a view of the forest.

1. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (113 reviews)
"My wife and I enjoyed our stay here. 10/10 experience."
United States
Winston
The price is ￥14,696
￥23,119 total
includes taxes & fees
Nov 16 - Nov 17
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A living room with a large tiger mural, a fireplace, a sofa, and a coffee table.

2. Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
Downtown
10.0 out of 10, Exceptional, (23 reviews)
"Great host! We had a great experience during our stay. "
United States
David E.
The price is ￥25,429
￥58,117 total
includes taxes & fees
Oct 26 - Oct 27
Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
A modern kitchen with granite countertops, stainless steel appliances, and pendant lighting.

3. The Nest Above - Sparrow Suite

The Nest Above - Sparrow Suite
Downtown
10.0 out of 10, Exceptional, (1 review)
"Charming stay in the downtown area. Walking distance to restaurants and events on Ramcat Alley. We enjoyed our stay and wipp stay again on our next trip to the upstate."
United States
Deborah R.
The Nest Above - Sparrow Suite
A modern kitchen with a central island, wooden cabinets, and a built-in refrigerator.

4. 3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
Seneca
9.8 out of 10, Exceptional, (12 reviews)
"Easy check in, pet-friendly, great location!!"
United States
Jason M.
The price is ￥35,555
￥60,664 total
includes taxes & fees
Oct 19 - Oct 20
3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
A bedroom with a bed, a dresser, a nightstand, a lamp, and a painting on the wall.

5. Renovated 3BR near Lake Keowee & Clemson

Renovated 3BR near Lake Keowee & Clemson
Seneca
10.0 out of 10, Exceptional, (2 reviews)
"Fantastic location and really nicely done home. It was a perfect touch having a desk in one of the rooms to be able to get work done."
United States
Brenda B.
The price is ￥27,306
￥58,096 total
includes taxes & fees
Oct 20 - Oct 21
Renovated 3BR near Lake Keowee & Clemson
A blue building with a wooden deck and two Adirondack chairs.

6. Cozy Clemson TIny House Cabin

Cozy Clemson TIny House Cabin
Seneca
10.0 out of 10, Exceptional, (4 reviews)
"Extremely clean and well maintained, suited our needs for a long weekend just fine. We even cooked a couple of meals. We enjoyed using the fire pit for the first campfire of the season."
United States
Rebecca J.
The price is ￥19,753
￥34,591 total
includes taxes & fees
Oct 19 - Oct 20
Cozy Clemson TIny House Cabin
A bedroom with a bed, a nightstand, a lamp, a window with blinds, a ceiling fan, and a painting on the wall.

7. Peaceful 3-bedroom home 4 miles from Clemson.

Peaceful 3-bedroom home 4 miles from Clemson.
Seneca
The price is ￥17,066
￥45,020 total
includes taxes & fees
Oct 19 - Oct 20
Peaceful 3-bedroom home 4 miles from Clemson.
Room

8. 13 Min Oconee Nuclear 15 Min Clemson Stadium

13 Min Oconee Nuclear 15 Min Clemson Stadium
Seneca
The price is ￥20,100
￥25,237 total
includes taxes & fees
Oct 25 - Oct 26
13 Min Oconee Nuclear 15 Min Clemson Stadium
A wooden deck with a railing overlooking a forested area during sunset.

9. Waterfront 3br home on Lake Hartwell near Clemson

Waterfront 3br home on Lake Hartwell near Clemson
Seneca
9.8 out of 10, Exceptional, (17 reviews)
"Planning was super simple and the host is very responsive!"
United States
Trevor&Shaya Z.
The price is ￥40,611
￥85,868 total
includes taxes & fees
Oct 19 - Oct 20
Waterfront 3br home on Lake Hartwell near Clemson
A bedroom with a bed, dresser, mirror, ceiling fan, and a door.

10. Walk to Boat Ramp Lake Keowee w/ Parking + Firepit

Walk to Boat Ramp Lake Keowee w/ Parking + Firepit
Seneca
2.0 out of 10, (1 review)
The price is ￥20,163
￥67,420 total
includes taxes & fees
Oct 19 - Oct 20
Walk to Boat Ramp Lake Keowee w/ Parking + Firepit
A modern kitchen with white cabinetry, a central island, and a large window.

11. The Big Golf House- 10 miles to Clemson

The Big Golf House- 10 miles to Clemson
Seneca
10.0 out of 10, Exceptional, (4 reviews)
"Great house and host!"
United States
David E.
The price is ￥40,105
￥95,927 total
includes taxes & fees
Oct 26 - Oct 27
The Big Golf House- 10 miles to Clemson
A bedroom with a wooden headboard, white bedding, and a dark blue throw blanket.

12. Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
Seneca
10.0 out of 10, Exceptional, (16 reviews)
"Perfect pet friendly spot to enjoy a weekend getaway! Quiet campground, homey vibe, and awesome location!"
United States
Josie G.
The price is ￥23,703
￥31,809 total
includes taxes & fees
Oct 19 - Oct 20
Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
A covered porch with wicker furniture, a wooden table, and a ceiling fan.

13. Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
Seneca
9.6 out of 10, Exceptional, (12 reviews)
"Everything was lovely."
United States
Allison C.
The price is ￥51,564
￥109,805 total
includes taxes & fees
Oct 19 - Oct 20
Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
A spacious living room with a sofa, chairs, a wooden coffee table, and a fireplace.

14. Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock
Seneca
8.0 out of 10, Very good, (7 reviews)
"Adorable and clean house! The yard is beautiful "
United States
Diana H.
The price is ￥25,941
￥46,264 total
includes taxes & fees
Oct 19 - Oct 20
Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock
A compact living space with a sofa, a chair, a coffee table, and a kitchenette area.

15. Camping on Fancy-Perfect for small family getaway or couples retreat!

Camping on Fancy-Perfect for small family getaway or couples retreat!
Seneca
10.0 out of 10, Exceptional, (2 reviews)
"Perfect space for me and my husband to stay for family weekend at Clemson. Perfectly located, comfortable, and the hostess was incredibly kind and thoughtful.We will definitely be staying here again."
United States
Regina J.
The price is ￥20,859
￥37,894 total
includes taxes & fees
Oct 19 - Oct 20
Camping on Fancy-Perfect for small family getaway or couples retreat!
A forest clearing with a central fire pit surrounded by logs.

16. Tiny House - Slice of Heaven Walhalla

Tiny House - Slice of Heaven Walhalla
Walhalla
9.4 out of 10, Exceptional, (33 reviews)
"It was a nice stay "
United States
Anthony D.
The price is ￥21,333
￥35,286 total
includes taxes & fees
Oct 19 - Oct 20
Tiny House - Slice of Heaven Walhalla
A cozy living room with a fireplace, a dining area with a table and chairs, and a large wooden door.

17. Clemson Memorabilia House

Clemson Memorabilia House
3.0 star property
Clemson
9.6 out of 10, Exceptional, (10 reviews)
"We enjoyed our stay, it was the perfect size for our family of four. "
United States
Ashley
The price is ￥14,064
￥37,539 total
includes taxes & fees
Oct 19 - Oct 20
Clemson Memorabilia House
A white house with a sloped roof, surrounded by trees and a garden.

18. Clemson Game Day Cottage w/ Fire Pit

Clemson Game Day Cottage w/ Fire Pit
3.0 star property
Clemson
10.0 out of 10, Exceptional, (1 review)
The price is ￥22,755
￥42,424 total
includes taxes & fees
Oct 19 - Oct 20
Clemson Game Day Cottage w/ Fire Pit
A lakeside cabin with a dock, a floating platform, and a house in the background.

19. Lakefront Private Cove Retreat w/ Sandy Beach, Dock, Hot Tub + Boat & Ski Option

Lakefront Private Cove Retreat w/ Sandy Beach, Dock, Hot Tub + Boat & Ski Option
West Union
9.6 out of 10, Exceptional, (17 reviews)
"Great home. Neat and Clean. We had family 3-70 and there was something for everyone to do and enjoy during our stay. Host was very prompt with communication and answering my questions. Would stay here again."
United States
April O.
The price is ￥94,649
￥208,234 total
includes taxes & fees
Oct 27 - Oct 28
Lakefront Private Cove Retreat w/ Sandy Beach, Dock, Hot Tub + Boat & Ski Option
A modern kitchen with stainless steel appliances, a central island, and a dining area with a wooden table and chairs.

20. Contemporary Hideout - 7min to Clemson University

Contemporary Hideout - 7min to Clemson University
Central
9.0 out of 10, Wonderful, (2 reviews)
"Spacious, clean, comfy"
United States
J H.
The price is ￥12,484
￥54,418 total
includes taxes & fees
Oct 19 - Oct 20
Contemporary Hideout - 7min to Clemson University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Seneca Hotel Reviews

Lakeside Lodge Clemson

Lakeside Lodge Clemson

10/10 Excellent
"Excellent stay. Very beautiful property, room was clean and comfortable. Staff was very friendly and helpful. We had a wonderful dinner at the onsite restaurant. Would definitely stay again if in the area."
Ann 1-night trip
Posted 11 hours ago
Lakeside Lodge Clemson

Find out more about Seneca

Search for holiday rentals in Seneca on Expedia! You can easily find your home rentals, villas, holiday apartments in Seneca using one of the methods below:

  • View our selection of featured holiday rentals in Seneca
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Look no further and take a look at our great range of rental properties in Seneca!

Frequently asked questions

Are there vacation rentals in Seneca?

Yes, there are vacation rentals in Seneca close to Blue Ridge Arts Center, or you can go with a more secluded option if you'd like a relaxing place to stay. Discover why Seneca is known for its marina and lakeside. While you're here, grab a bite or have a drink at the coffeehouses.

What's the top vacation rental in Seneca?

Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water: This highly rated vacation home rental in Seneca is located on a lake and has a fireplace, a patio, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. You can relax into your vacation with a garden and a selection of games. Some other homes for rent in Seneca include Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub and New to VRBO! Big water views, private dock, pool table, 15 min Clemson!.

How many vacation rentals are there in Seneca?

Choose from 217 Expedia vacation rentals in Seneca for a memorable vacation.

What’s there to see and do in Seneca?

Cultural attractions include The Gauntlet and Oconee Community Theatre, whereas Lake Keowee and Lake Hartwell are a couple of picturesque spots to enjoy the outdoors. While here, Keowee Key Golf Course and Oconee County Library Seneca Branch are other places worth a visit.

What’s a vacation rental in Seneca like?

A vacation rental is a private property where you can stay for a few weeks or just a few days in Seneca. Vacation rentals offer amenities such as WiFi and washers and dryers so you'll have all the conveniences of home. If you're concerned about cleanliness, vacation rentals can provide a sense of security away from shared hotel elevators and busy concierge desks while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for family trips.