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Seneca Vacation Rentals

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Check prices for these dates

In two weeks
Sep 12 - Sep 14
In two months
Oct 24 - Oct 26
In three months
Nov 21 - Nov 23
In four months
Dec 19 - Dec 21

Vacation Rentals in Seneca

Postcard Cabins Lake Hartwell
Exterior

Postcard Cabins Lake Hartwell

2.0 star property
9.8 out of 10, Exceptional, (25)
"Lovely stay! Highly recommend!!!"
The price is ￥13,123
￥20,111 total
includes taxes & fees
Sep 1 - Sep 2
Postcard Cabins Lake Hartwell
LAKE KEOWEE LAKEVIEW CABIN WITH DOCK CLOSE TO CLEMSON
Dining

LAKE KEOWEE LAKEVIEW CABIN WITH DOCK CLOSE TO CLEMSON

9.8 out of 10, Exceptional, (82)
"Our stay was very nice, and I would recommend this cabin. "
LAKE KEOWEE LAKEVIEW CABIN WITH DOCK CLOSE TO CLEMSON
Fabulous Tiny House with AC in charming Seneca
Microwave, stovetop

Fabulous Tiny House with AC in charming Seneca

9.4 out of 10, Exceptional, (3)
"I couldn’t have been happier with my stay. Everything was top notch. "
Fabulous Tiny House with AC in charming Seneca
Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock
Property grounds

Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock

9.6 out of 10, Exceptional, (170)
"We meet an have family vacation every year in Tennessee, this year decided to go here, what a great decision. We all loved the Lake tubing, grilling hamburgers eating on beautiful porch and the house was perfect for our family be comfortable. We definitely would stay again. Thank you for letting us use your house make another sweet memory for our family "
Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock
Large family home with dock on Lake Keowee!
Property grounds

Large family home with dock on Lake Keowee!

9.8 out of 10, Exceptional, (114)
"The house and location is beautiful. The home offers everything you need. Lake Keowee is so beautiful."
Large family home with dock on Lake Keowee!
4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake.
Property grounds

4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake.

9.8 out of 10, Exceptional, (358)
"Wonderful lake house inside and out.Beautiful landscaping. Even on a rainy day, the generous covered deck with lots of seating allows outdoor time."
4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake.
Fall fun at the cabin! Convenient to Lake Keowee and Clemson

Fall fun at the cabin! Convenient to Lake Keowee and Clemson

9.0 out of 10, Wonderful, (78)
"Very peaceful, clean and relaxing. Will definitely go back."
Fall fun at the cabin! Convenient to Lake Keowee and Clemson
Luxury 4BR/4BA Lake Keowee Retreat- Mountain Cabin Vibes + Private Dock
Exterior

Luxury 4BR/4BA Lake Keowee Retreat- Mountain Cabin Vibes + Private Dock

10.0 out of 10, Exceptional, (5)
Luxury 4BR/4BA Lake Keowee Retreat- Mountain Cabin Vibes + Private Dock
6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.
Property grounds

6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.

9.8 out of 10, Exceptional, (150)
"House was very nice set up.description of property wasvery accurate. Steve the manager was very help full on the process checking and out."
6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.
5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!
Exterior

5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!

10.0 out of 10, Exceptional, (86)
"We had a perfect family vacation on the lake. The layout and design of the property is so thoughtful and well done. There was plenty of space for our large group to spread out, play, and relax. The kitchen is well appointed with everything you need entertain. We could not have had a better time. "
5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!
Lake Front, Quiet, Private cove on 4.75 acres, Canoe, 2 Kayak, 2 boat docks
Property grounds

Lake Front, Quiet, Private cove on 4.75 acres, Canoe, 2 Kayak, 2 boat docks

10.0 out of 10, Exceptional, (224)
"Excellent host and lovely place."
Lake Front, Quiet, Private cove on 4.75 acres, Canoe, 2 Kayak, 2 boat docks
Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub
Exterior

Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub

9.8 out of 10, Exceptional, (50)
"A beautiful setting and lovely, well equipped home with many games and activities to keep everyone busy. "
Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub
Incredible 10 BR home with pool
Property grounds

Incredible 10 BR home with pool

9.6 out of 10, Exceptional, (5)
"House is virtually brand new. Well decorated. Spacious. Clean as a whistle. Heated pool/ hot tub. Billiards room. And a great property management company. "
Incredible 10 BR home with pool
Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub
Outdoor spa tub

Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub

10.0 out of 10, Exceptional, (147)
"Great set up for family Christmas reunion "
Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub
Enjoy one of our RV units son less of a headache for you this vacation!
Smart TV, fireplace

Enjoy one of our RV units son less of a headache for you this vacation!

The price is ￥17,517
￥29,487 total
includes taxes & fees
Sep 3 - Sep 4
Enjoy one of our RV units son less of a headache for you this vacation!
New to VRBO! Big water views, private dock, pool table, 15 min Clemson!
Terrace/patio

New to VRBO! Big water views, private dock, pool table, 15 min Clemson!

10.0 out of 10, Exceptional, (43)
"Went for Easter holiday with family. Perfect location - nice and quiet. Family all had a good visit. "
New to VRBO! Big water views, private dock, pool table, 15 min Clemson!
Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!
Property grounds

Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!

10.0 out of 10, Exceptional, (54)
"Great location on the lake. Easy to get to the marina and rent a boat. First time on the lake and we had an awesome time. "
Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!
Charming 3-bedroom house with WiFi and AC in serene Seneca on Lake Hartwell
Property grounds

Charming 3-bedroom house with WiFi and AC in serene Seneca on Lake Hartwell

10.0 out of 10, Exceptional, (6)
Charming 3-bedroom house with WiFi and AC in serene Seneca on Lake Hartwell
Carolina’s Cottage Cove-Lake Keowee
Outdoor spa tub

Carolina’s Cottage Cove-Lake Keowee

9.6 out of 10, Exceptional, (20)
"We absolutely LOVED this house and would love to stay again! Next time a little longer! "
Carolina’s Cottage Cove-Lake Keowee
Wooded Cottage - 3 Mi to Clemson University
Cottage (1 Bedroom) | Interior

Wooded Cottage - 3 Mi to Clemson University

3.0 star property
10.0 out of 10, Exceptional, (1)
Wooded Cottage - 3 Mi to Clemson University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Seneca Hotel Reviews

Find out more about Seneca

Find out more about Seneca

Search for holiday rentals in Seneca on Expedia! You can easily find your home rentals, villas, holiday apartments in Seneca using one of the methods below:

  • View our selection of featured holiday rentals in Seneca
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Look no further and take a look at our great range of rental properties in Seneca!

Explore a world of travel with Expedia

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Frequently asked questions

Are there vacation rentals in Seneca?

Yes, there are vacation rentals close to popular attractions in Seneca, or you can select a secluded option if you'd like a relaxing place to stay. Discover why Seneca is known for its marina and lakeside. While you're here, grab a bite or have a drink at the coffeehouses.

What's the top vacation rental in Seneca?

4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake. : This highly rated vacation home rental in Seneca is located on a lake and has a fireplace, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and an arcade game room. Some other homes for rent in Seneca include Large family home with dock on Lake Keowee! and 6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water..

How many vacation rentals are there in Seneca?

Choose from 204 Expedia vacation rentals in Seneca for a memorable vacation.

What’s there to see and do in Seneca?

Cultural attractions include The Gauntlet and Oconee Community Theatre, whereas Keowee Reservoir and Lake Keowee are a couple of picturesque spots to enjoy the outdoors. While here, Keowee Key Golf Course and Lake Hartwell are other places worth a visit.

What’s a vacation rental in Seneca like?

A vacation rental is a private property where you can stay for a few weeks or just a few days in Seneca. Vacation rentals offer amenities such as WiFi and washers and dryers so you'll have all the conveniences of home. If you're concerned about cleanliness, vacation rentals can provide a sense of security away from shared hotel elevators and busy concierge desks while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for family trips.