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Compare 114 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1006)
"The pool the happy hour was really nice very relaxed nice activities front desk was very helpful at all times"
The price is ¥13,233
¥15,214 total
includes taxes & fees
Sep 4 - Sep 5
Drury Inn & Suites Sikeston, MO

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1018)
"Very nice hotel and nice staff "
The price is ¥13,233
¥14,927 total
includes taxes & fees
Sep 4 - Sep 5
Drury Plaza Hotel Cape Girardeau Conference Center

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1007)
"Very nice property Friendly helpful staff"
The price is ¥11,321
¥13,014 total
includes taxes & fees
Sep 15 - Sep 16
Pear Tree Inn Sikeston

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1005)
"Excellent place to stay "
The price is ¥10,292
¥11,611 total
includes taxes & fees
Sep 1 - Sep 2
Pear Tree Inn Cape Girardeau Near the Medical Center

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1010)
"Employees were extremely helpful and happy to help!"
The price is ¥13,233
¥13,990 total
includes taxes & fees
Sep 4 - Sep 5
Drury Inn & Suites Jackson MO

Quality Inn Cairo I-57

2.5 star property
6.6 out of 10, (265)
"The hotel is in need of some serious upkeep and cleaning. It is in fairly poor condition, but it the only hotel in town."
The price is ¥10,026
¥11,126 total
includes taxes & fees
Oct 1 - Oct 2
Quality Inn Cairo I-57

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (986)
"Easy access and parking"
The price is ¥13,233
¥14,927 total
includes taxes & fees
Sep 7 - Sep 8
Drury Inn & Suites Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
8.8 out of 10, Excellent, (607)
"Excellent place to stay. Breakfast was good and staff was friendly. "
The price is ¥12,176
¥13,177 total
includes taxes & fees
Sep 1 - Sep 2
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1005)
"We enjoyed the quick check in and how quiet the property was. "
The price is ¥10,292
¥11,611 total
includes taxes & fees
Sep 1 - Sep 2
Pear Tree Inn Cape Girardeau West

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (740)
"Nice and clean hotel friendly service"
The price is ¥16,124
¥18,190 total
includes taxes & fees
Sep 7 - Sep 8
Hampton Inn Cape Girardeau I 55 East

The Riverview

2.0 star property
9.4 out of 10, Exceptional, (399)
"From the moment we walked in we were impressed with the customer service, facility & cleanliness. We enjoyed every part of our one night stay! We would definitely stay here again "
The price is ¥15,484
¥17,468 total
includes taxes & fees
Sep 2 - Sep 3
The Riverview

Fairfield Inn & Suites by Marriott Sikeston

2.5 star property
9.4 out of 10, Exceptional, (20)
"Nice hotel "
The price is ¥14,852
¥16,816 total
includes taxes & fees
Sep 7 - Sep 8
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (126)
"The hotel was very clean and updated and the staff was super friendly and very informative!"
The price is ¥13,676
¥15,428 total
includes taxes & fees
Sep 7 - Sep 8
Fairfield Inn & Suites by Marriott Cape Girardeau

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (378)
"Great location and clean room. Plenty of food and shopping nearby."
The price is ¥15,624
¥17,690 total
includes taxes & fees
Sep 7 - Sep 8
Hampton Inn Sikeston

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
8.4 out of 10, Very Good, (670)
"Everything was nice"
The price is ¥8,094
¥9,224 total
includes taxes & fees
Sep 14 - Sep 15
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1003)
"The hotel was very nice and the staff were super helpful. I would stay here again!"
The price is ¥15,146
¥17,087 total
includes taxes & fees
Sep 7 - Sep 8
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (398)
"I consistently choose to stay there due to positive past encounters."
The price is ¥9,682
¥10,744 total
includes taxes & fees
Sep 8 - Sep 9
Quality Inn Charleston - Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
8.6 out of 10, Excellent, (425)
"Close in eating and shopping "
The price is ¥16,176
¥18,315 total
includes taxes & fees
Sep 7 - Sep 8
Holiday Inn Express & Suites Sikeston Southwest by IHG

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (441)
"Very clean and upscale hotel."
The price is ¥18,381
¥20,829 total
includes taxes & fees
Sep 14 - Sep 15
Courtyard by Marriott Cape Girardeau Downtown

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very Good, (1003)
"Staff was friendly and room was very clean. A very comfortable stay"
The price is ¥12,373
¥14,103 total
includes taxes & fees
Sep 14 - Sep 15
Best Western Plus Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place to stay in Scott City?

Drury Plaza Hotel Cape Girardeau Conference Center, located 6.9 mi (11.1 km) from the heart of Scott City, is a top choice for your stay based on our traveler data. Other good choices for your trip to the area are The Riverview and Pear Tree Inn Cape Girardeau West. See all available top hotels, or vacation rentals in Scott City.

What are some of the best vacation home rentals that Scott City has to offer?

Building at Cape Girardeau Regional Airport: This Scott City vacation home rental is near the airport and offers air-conditioning to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Scott City.

If I need to cancel my hotel reservation in Scott City, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Scott City.

Where can I learn more about changing or cancelling my trip to Scott City?

For more information about rescheduling or cancelling your trip to Scott City, go to https://www.expedia.com/service/.

What is staying in Scott City like?

Travelers to Scott City will find plenty to explore and enjoy. There are 112 hotels and other accommodations in the surrounding area. Find out more about Scott City.

What should I see while I'm in Scott City?

The picturesque setting of Shawnee National Forest and Mississippi River exemplify the area's natural beauty. You'll also find Isle Casino Cape Girardeau and Show Me Center in the area. Check out what more to see and do in Expedia's Scott City guide.

What's the weather like in Scott City?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Scott City is 59 inches.