Find hotels in Santa Mesa, Manila from ¥2,548
Change your mind
Be picky
Go beyond your typical stay in Santa Mesa
Check prices for these dates
Discover 4,841 Santa Mesa hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.
Our top choices for Santa Mesa hotels

Manila Prince Hotel
Manila Prince Hotel

ELIJAH HOTEL
ELIJAH HOTEL

Sulit Budget Hotel
Sulit Budget Hotel

The Bellevue Manila
The Bellevue Manila

Town and Country Hotel - V. Mapa
Town and Country Hotel - V. Mapa

Halina Drive Inn Hotels - Sta Mesa
Halina Drive Inn Hotels - Sta Mesa
Where to stay in Santa Mesa

Bonifacio Global City
Financial district BGC boasts residential condos, corporate offices, and retail spaces, with attractions like Bonifacio High Street and Uptown Mall. Enjoy Track 30th's urban park and easily navigate pedestrian-friendly roads.

Malate
Serving as Manila's commerce and tourism hub, Malate offers promenades and parks by Manila Bay, the Manila Zoological and Botanical Garden, and the Cultural Center of the Philippines Complex. Accessible via main roads and LRT-1, the district features small hotels, specialty restaurants, and cafes.

Makati Central Business District
Vibrant commercial district, Makati CBD boasts premier shopping at Ayala Center and cultural experiences at Filipinas Heritage Library. Enjoy Ayala Triangle Gardens, Salcedo Community Market, and easy access to public transportation.

Ortigas Center
Central business district boasting shopping malls like SM Megamall and Shangri-la Plaza, office skyscrapers, and vibrant nightlife. Explore attractions such as EDSA Shrine and St. Francis Square.

Alabang
One of the most modern corners of Metro Manila, this sleek region of Muntinlupa City is known for its vast malls and stylish skyscrapers.
Top Santa Mesa Hotel Reviews
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels in top Manila neighborhoods
- Hotels in Bonifacio Global City
- Hotels in Malate
- Hotels in Makati Central Business District
- Hotels in Ortigas Center
- Hotels in Alabang
- Hotels in Ermita
- Hotels in Cubao
- Hotels in Makati Downtown
- Hotels in Tambo
- Hotels in Barangay 76
- Hotels in San Lorenzo
- Hotels in Intramuros
- Hotels in Eastwood
- Hotels in Bel-Air
- Hotels in Poblacion
- Hotels in Legazpi Village
- Hotels in Forbes Park
- Hotels in Binondo
- Hotels in Salcedo Village
- Hotels in Diliman
Hotels near popular Manila Attractions
More Accommodation Types in Santa Mesa
Hotels Close to Nearby Airports
Explore more hotels
- Seda BGC (Bonifacio Global City)
- Solaire Resort Entertainment City
- The Peninsula Manila
- Kabayan Hotel
- Hotel 101 - Manila
- Conrad Manila
- Holiday Inn Express Manila Newport City by IHG
- TRYP by Wyndham Mall of Asia Manila
- Hilton Manila Newport World Resorts
- Makati Shangri-La, Manila
- Hyatt Regency Manila, City of Dreams
- Makati Diamond Residences