Photo by Tahino2000

Find hotels in Santa Fe de Antioquia from ¥7,347

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Fe de Antioquia hotels

Hotel San Sebastian del Tonusco

Hotel San Sebastian del Tonusco
3.0 star property
Zona Colonial
9.0 out of 10, Wonderful, (40)
"I was welcomed by three employees of the hotel with such warmth, I immediately felt at home. Laura, in particular, was so attentive to me during my entire stay. I was sad to leave. A wonderful experience. The only caveat is that it's a little far from the main town, but the hotel can arrange for a Tuk Tuk for you (very cheap and fun). "
United States
Timothy
The price is ¥14,695
¥14,695 total
Jan 13 - Jan 14, 2026
Hotel San Sebastian del Tonusco

Ivanna Hotel Campestre - Santa Fe de Antioquia

Ivanna Hotel Campestre - Santa Fe de Antioquia
4.5 star property
Santa Fe de Antioquia
6.0 out of 10, (2)
"Lol, where do i start...there was so many issues. Everything we asked for when it came to lunch and dinner that was on the menu was not available or they ran out of. My room was "the quadruple mountain view" but there was no but trees. The bathroom was not in the room and also i asked for extra towels and they could not accommodate us with any new towels. The room was super tiny when we are a family of 4. I will never come here again."
United States
Randolph
The price is ¥10,921
¥10,921 total
Jan 12 - Jan 13, 2026
Ivanna Hotel Campestre - Santa Fe de Antioquia

Hosteria Tonusco Campestre

Hosteria Tonusco Campestre
3.0 star property
Santa Fe de Antioquia
8.8 out of 10, Excellent, (25)
Unwind at this tranquil retreat with 2 hot tubs and an outdoor pool. After pampering spa treatments, enjoy drinks at the poolside bar. Located near Museo Juan del Corral and Bolivar Square with free breakfast, WiFi, and parking.

"Love this plce"
United States
juan fernando
The price is ¥12,164
¥12,164 total
Dec 14 - Dec 15
Hosteria Tonusco Campestre

Hotel Boutique Al Alma

Hotel Boutique Al Alma
4.5 star property
Zona Colonial
9.4 out of 10, Exceptional, (51)
This hotel offers complimentary breakfast and beach cabanas, plus rejuvenating deep-tissue massages. Swim in the outdoor pool or dine at the café. The bar provides evening relaxation near Museo Juan del Corral and Bolivar Square.

"Amazing hotel, we loved every corner. Quiet street and great ambiance."
United States
Paula
Hotel Boutique Al Alma

Hotel Mariscal Robledo

Hotel Mariscal Robledo
3.0 star property
Zona Colonial
9.4 out of 10, Exceptional, (219)
Surrounded by colonial treasures like the Cathedral and Casa Atanasio Girardot, this tranquil hotel offers a refreshing outdoor pool and rejuvenating facials. Enjoy poolside drinks, unwind in the steam room, and savor complimentary breakfast.

"The reception, the rooms and the breakfast buffet were absolutely wonderful! Would love to go back and stay here again. "
United States
Lily
The price is ¥21,308
¥21,308 total
Dec 14 - Dec 15
Hotel Mariscal Robledo

Hotel Porton del Sol

Hotel Porton del Sol
3.0 star property
Santa Fe de Antioquia
9.0 out of 10, Wonderful, (14)
Majestic outdoor pools await at this tranquil hotel near Museo Juan del Corral and Bolivar Square. Unwind with rejuvenating spa services, sip refreshing drinks at the bar, or enjoy treats at the café surrounded by lush garden scenery.

"Very nice place to stay during holiday"
United States
Ruben Dario
Hotel Porton del Sol

HOTEL KALMA

HOTEL KALMA
3.5 star property
Santa Fe de Antioquia
9.8 out of 10, Exceptional, (7)
Discover this colonial-era hotel just minutes from Museo Juan del Corral and Bolivar Square. Take a dip in the outdoor pool, enjoy a garden stroll, or savor complimentary breakfast on the terrace.

"The amazing staff made our stay delightful."
United States
charles
HOTEL KALMA

Arde La Selva

Arde La Selva
4.0 star property
Santa Fe de Antioquia
9.8 out of 10, Exceptional, (17)
Set in Santa Fe de Antioquia near Museo Juan del Corral and Bolivar Square, this hotel offers 2 outdoor pools and a poolside bar. Enjoy free breakfast, WiFi, and parking after relaxing with hot stone massages.

"Very helpful staff and amazing food."
United States
Norge
The price is ¥21,905
¥21,905 total
Dec 16 - Dec 17
Arde La Selva

Curazao Hotel

Curazao Hotel
3.0 star property
Zona Colonial
9.8 out of 10, Exceptional, (6)
Unwind at this charming hotel near Cathedral of Santa Fe de Antioquia. Relax with spa treatments or enjoy free breakfast before exploring nearby Casa Atanasio Girardot. The outdoor pool and restaurant offer perfect retreats after sightseeing.

"Great location … good vreakfeast "
Mexico
Eva
The price is ¥7,795
¥7,795 total
Dec 14 - Dec 15
Curazao Hotel

Hostería Fundadores

Hostería Fundadores
3.0 star property
Santa Fe de Antioquia
7.6 out of 10, Good, (55)
This spa hotel boasts a full-service spa, outdoor pool, and hot tub for ultimate relaxation. Grab a bite at the restaurant or enjoy a drink at the bar. Located near Casa Atanasio Girardot and the cathedral with free WiFi and parking.

"It’s not fancy but it has the basic things you need. The staff are nice "
Canada
michael
The price is ¥9,797
¥10,042 total
Dec 14 - Dec 15
Hostería Fundadores

Hotel Primavera Santa Fe

Hotel Primavera Santa Fe
3.0 star property
Santa Fe de Antioquia
10.0 out of 10, Exceptional, (1)
Unwind in this centrally located hotel near Cathedral of Santa Fe de Antioquia. Enjoy daily continental breakfast, free WiFi, and attentive housekeeping service. The historic Casa Atanasio Girardot awaits just minutes away.

"Excelente atención personalizada, nos encantó sentirnos más cerca de la vida cotidiana de Colombia, con estas acciones dirías hacen un mejor país."
Mexico
Soluciones
Hotel Primavera Santa Fe

Casa Al Alma

Casa Al Alma
3.0 star property
Zona Colonial
9.2 out of 10, Wonderful, (12)
Unwind at this inviting hotel near Museo Juan del Corral and Bolivar Square. Enjoy the outdoor pool, relaxing massages, and complimentary breakfast. Grab refreshments at the café or bar after exploring local attractions.

"Very nice place to stay . Only 5 rooms … very cozy place ….the manager is very helpful and will do whatever he can for you .. "
United States
Mark
The price is ¥16,899
¥16,899 total
Jan 13 - Jan 14, 2026
Casa Al Alma

Finca Hotel Guadalupe

Finca Hotel Guadalupe
3.0 star property
Santa Fe de Antioquia
7.8 out of 10, Good, (13)
Located in Santa Fe de Antioquia, this hotel offers a welcoming retreat with a restaurant and bar. Enjoy complimentary breakfast, WiFi and parking while exploring nearby Museo Juan del Corral.

"Very quite very friendly staff lovable watch dog tequila would visit again "
United States
gary
The price is ¥16,673
¥16,673 total
Dec 14 - Dec 15
Finca Hotel Guadalupe

Finca Hotel La Estancia

Finca Hotel La Estancia
3.0 star property
Santa Fe de Antioquia
6.0 out of 10, (1)
Unwind at this tranquil countryside hotel featuring an inviting outdoor pool and poolside bar. Just minutes from Museo Juan del Corral and Bolivar Square, guests enjoy complimentary breakfast, WiFi, and parking.

"Un buen lugar pero ponen muy alto el volumen de la musica en la piscina, tambien si deseas salir en la noche del hotel no encuentra como solicitar la apertura de la puerta"
Colombia
Julian
Finca Hotel La Estancia

Casa Bixa Hotel Boutique -Santa Fe de Antioquia- Mayores de 12 años

Casa Bixa Hotel Boutique -Santa Fe de Antioquia- Mayores de 12 años
3.5 star property
Zona Colonial
10.0 out of 10, Exceptional, (48)
Immerse yourself in Santa Fe de Antioquia at this adults-only retreat featuring an outdoor pool with poolside bar. Savor international dishes at Óleo Bistró Restaurante, just minutes from Museo Juan del Corral. Enjoy free breakfast, WiFi and attentive service amid lush garden surroundings.

"My family and I are happy we stayed here. The place was beautiful, but the staff was the best part. Always asking and making sure everything was ok. "
United States
Isaias
The price is ¥22,242
¥22,242 total
Dec 14 - Dec 15
Casa Bixa Hotel Boutique -Santa Fe de Antioquia- Mayores de 12 años

Selva Maria Hotel Boutique

Selva Maria Hotel Boutique
3.0 star property
Zona Colonial
10.0 out of 10, Exceptional, (8)
Enchanting boutique hotel just moments from Bolivar Square and local museums. Wake up to a delicious cooked-to-order breakfast, connect with free WiFi, and enjoy impeccable daily housekeeping service for a refreshing Colombian retreat.

"The hotel and the rooms are cozy and very clean, The staff are super polite, friendly and professional, they go far and beyond to meet your needs and make you feel welcome. We recommend to any one looking for a quiet and comfortable stay, close to all amenities. Breakfast was excellent. "
Canada
Walter
The price is ¥9,111
¥9,111 total
Dec 17 - Dec 18
Selva Maria Hotel Boutique

Angel de Santa Fe by Bernalo Hotels

Angel de Santa Fe by Bernalo Hotels
3.0 star property
Santa Fe de Antioquia
The price is ¥13,553
¥13,553 total
Dec 21 - Dec 22
Angel de Santa Fe by Bernalo Hotels

SANTA FE DE ANTIOQUIA

SANTA FE DE ANTIOQUIA
2.0 star property
Santa Fe de Antioquia
8.0 out of 10, Very Good, (1)
Immerse yourself in colonial charm at this aparthotel with 6 sparkling outdoor pools and lush garden spaces. Located near Cathedral of Santa Fe de Antioquia and Bolivar Square, you'll enjoy free WiFi and easy exploration of historic sites.

"Todo Ok"
Costa Rica
Nohelys
The price is ¥13,708
¥16,361 total
Dec 15 - Dec 16
SANTA FE DE ANTIOQUIA

casa morales santa fe

casa morales santa fe
3.0 star property
Zona Colonial
The price is ¥9,950
¥9,950 total
Jan 1 - Jan 2, 2026
casa morales santa fe

Finca hotel mi refugio

Finca hotel mi refugio
2.0 star property
Santa Fé de Antioquia
Escape to this serene haven with a refreshing outdoor pool. Free WiFi and parking enhance convenience, while Museo Juan del Corral and Bolivar Square offer nearby cultural exploration. Surrounded by garden greenery for peaceful relaxation.
The price is ¥7,347
¥7,347 total
Dec 14 - Dec 15
Finca hotel mi refugio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Where to stay in Santa Fe de Antioquia

Find the best Santa Fe de Antioquia areas and neighborhoods for the activities you enjoy most.

Zona Colonial

If you're spending some time in Zona Colonial, Cathedral of Santa Fe de Antioquia and Casa Atanasio Girardot are top sights worth seeing.

Stay near popular Santa Fe de Antioquia attractions

Learn more about Santa Fe de Antioquia

Colonial architecture frames the cobblestone plaza where locals gather under the shade of Santa Barbara Church's impressive towers. Explore the Puente de Occidente suspension bridge nearby in Olaya or join weekend visitors sampling fresh fruit juices in the bustling market.

Pretty little colonial town just less than 2 hours drive from Medellín
Photo by Botak Jon
Open Photo by Botak Jon

Top Santa Fe de Antioquia Hotel Reviews

More cheap stays in Santa Fe de Antioquia

Frequently asked questions

What's the best place for a stay in Santa Fe de Antioquia?
Casa Bixa Hotel Boutique by HMC - Mayores de 12 años is a favorite with Expedia customers. This hotel offers free breakfast and a restaurant. Other favorite options based on traveler reviews include Hotel Boutique Al Alma and Hosteria Tonusco Campestre. See all available top hotels, or vacation rentals in Santa Fe de Antioquia.
What's the top vacation rental in Santa Fe de Antioquia?
La Gracia Hotel & Spa: This vacation home rental outside of Santa Fe de Antioquia offers a terrace, a garden, and free WiFi to help you feel perfectly comfortable in your new surroundings. Another good choice for your trip to Santa Fe de Antioquia is Santa Ana Colonial, Colonial Retreat w/ Private Pool & Lush Gardens. See all vacation rentals in Santa Fe de Antioquia.
If I need to cancel my hotel reservation in Santa Fe de Antioquia, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Fe de Antioquia.
Where can I learn more about changing or cancelling my trip to Santa Fe de Antioquia?
For more details about changing or cancelling your trip to Santa Fe de Antioquia, head over to our customer service page.
What's the best budget-friendly accommodation in Santa Fe de Antioquia?
Based on our traveler reviews, Hostal La Pola is a top choice for a less expensive stay. View all budget hotels in Santa Fe de Antioquia.
What's the best hotel when traveling with kids to Santa Fe de Antioquia?
La Ardilla de Santa Fe by Bernalo Hotels is a hotel with 2 outdoor pools and a free kids' club, and it's a top choice on Expedia for families. Find more child-friendly accommodations in Santa Fe de Antioquia.
What's the best pet-friendly place to stay in Santa Fe de Antioquia?
Hosteria Tonusco Campestre is a top hotel for people traveling with their pets, and offers 2 hot tubs and a full-service spa for its human guests. Other good choices to stay with your pet include Casa Al Alma and Casa Bixa Hotel Boutique by HMC - Mayores de 12 años. See more pet-friendly hotel accommodations in Santa Fe de Antioquia.
Where is the best place to stay near Cathedral of Santa Fe de Antioquia?
Adjacent to Cathedral of Santa Fe de Antioquia, Hotel Mariscal Robledo is one of the top choices for your stay based on our traveler data, and this 3-star hotel offers free breakfast and a restaurant. Other good options within a short distance include Hotel San Angel 2 and Hotel y Spa Santa Fe Colonial.
What about the best place to stay near Bolivar Square?
One of the top choices for your stay is Hotel Mariscal Robledo, located next to Bolivar Square, and this 3-star hotel offers free breakfast and a restaurant. Hotel y Spa Santa Fe Colonial and Hotel Caserón del Parque are two other good choices in the immediate area.
What's the best luxury place to stay in Santa Fe de Antioquia?
Hotel Boutique Al Alma is a luxury hotel with spa services and a deli, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Ivanna Hotel Campestre - Santa Fe de Antioquia. Find more luxury hotels in Santa Fe de Antioquia.
What are some accommodations with pools in Santa Fe de Antioquia?
Arde La Selva: Features 2 bars, 2 outdoor pools, and spa services. Casa Al Alma and Hotel Boutique Al Alma are two additional hotels with an onsite pool. View all hotels with pools in Santa Fe de Antioquia.
What is the best spa hotel in Santa Fe de Antioquia?
Arde La Selva is a highly recommended spa hotel with a restaurant. Spend an afternoon at the spa where you'll find hot stone massages and massage treatments. Other popular spa hotels in Santa Fe de Antioquia include Hotel Boutique Al Alma and Hosteria Tonusco Campestre. See all spa hotels in Santa Fe de Antioquia.
What's the top hotel in Santa Fe de Antioquia with a water park on-site or close by?
Ivanna Hotel Campestre - Santa Fe de Antioquia is a popular hotel featuring free water park access, 2 outdoor pools, and a restaurant. Another top water park hotel you might want to consider is Exclusivo, Privado y Hermoso lugar para descansar, sin restricciones !. Check out all hotels with or near waterparks in Santa Fe de Antioquia.
What is the best hotel near Jose Maria Cordova International Airport (MDE)?
Movich Hotel Las Lomas is a popular 4-star hotel featuring extended parking (for a fee) and a full-service spa. It's located a short 0.5 mi (0.9 km) from Jose Maria Cordova Intl. Airport. Other options near the airport are Casa Campestre Aeropuerto and Hotel Santiago de Arma.
What's it like to stay in Santa Fe de Antioquia?
Visitors can enjoy all that Santa Fe de Antioquia has to offer including the monuments, cathedral, and festivals. Tourists can also enjoy the city's riverfront, art, and theaters. In Santa Fe de Antioquia, there are 65 hotels and other accommodations to choose from. Find out more about Santa Fe de Antioquia.
What is there to see in Santa Fe de Antioquia?
Cultural venues include Casa Atanasio Girardot and Museo Juan del Corral. Landmarks like Bridge of the West, Cathedral of Santa Fe de Antioquia, and Bolivar Square might be worth a visit. You'll also find El Gaitero Ecopark and San Jeronimo Park in the area. Check out what more to see and do in Expedia's Santa Fe de Antioquia guide.
What's the weather like in Santa Fe de Antioquia?
The hottest months are usually August and July with an average temp of 66°F, while the coldest months are December and January with an average of 64°F. The rainiest months in Santa Fe de Antioquia are May, April, October, and November, with each month seeing an average of 16 inches of rainfall.

Explore a world of travel with Expedia