Find hotels in Santa Cruz, Manila from ¥2,940
Change your mind
Be picky
Go beyond your typical stay in Santa Cruz
Check prices for these dates
Discover 4,548 Santa Cruz hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Lucky Hotel Binondo
Lucky Hotel Binondo

Best Fortune Hotel
Best Fortune Hotel

Red Planet Manila Binondo
Red Planet Manila Binondo

Ramada by Wyndham Manila Central
Ramada by Wyndham Manila Central

Oriental Zen Suites
Oriental Zen Suites

Pristinehotel
Pristinehotel
Where to stay in Santa Cruz

Bonifacio Global City
Financial district BGC boasts residential condos, corporate offices, and retail spaces, with attractions like Bonifacio High Street and Uptown Mall. Enjoy Track 30th's urban park and easily navigate pedestrian-friendly roads.

Malate
Serving as Manila's commerce and tourism hub, Malate offers promenades and parks by Manila Bay, the Manila Zoological and Botanical Garden, and the Cultural Center of the Philippines Complex. Accessible via main roads and LRT-1, the district features small hotels, specialty restaurants, and cafes.

Makati Central Business District
Vibrant commercial district, Makati CBD boasts premier shopping at Ayala Center and cultural experiences at Filipinas Heritage Library. Enjoy Ayala Triangle Gardens, Salcedo Community Market, and easy access to public transportation.

Ortigas Center
Central business district boasting shopping malls like SM Megamall and Shangri-la Plaza, office skyscrapers, and vibrant nightlife. Explore attractions such as EDSA Shrine and St. Francis Square.

Alabang
One of the most modern corners of Metro Manila, this sleek region of Muntinlupa City is known for its vast malls and stylish skyscrapers.
Recent reviews of Santa Cruz hotels
Recent reviews of Santa Cruz hotels

Dusit Thani Manila
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels in top Manila neighborhoods
- Hotels in Bonifacio Global City
- Hotels in Malate
- Hotels in Makati Central Business District
- Hotels in Ortigas Center
- Hotels in Alabang
- Hotels in Ermita
- Hotels in Cubao
- Hotels in Makati Downtown
- Hotels in Tambo
- Hotels in San Lorenzo
- Hotels in Barangay 76
- Hotels in Eastwood
- Hotels in Intramuros
- Hotels in Poblacion
- Hotels in Bel-Air
- Hotels in Legazpi Village
- Hotels in Forbes Park
- Hotels in Salcedo Village
- Hotels in Diliman
- Hotels in Urdaneta
More Hotel Options in Santa Cruz
More Accommodation Types in Santa Cruz
Hotels Close to Nearby Airports
Explore more hotels
- Kabayan Hotel
- Seda BGC (Bonifacio Global City)
- Hotel 101 - Manila
- Conrad Manila
- Holiday Inn Express Manila Newport City by IHG
- Solaire Resort Entertainment City
- New World Makati Hotel
- Hilton Manila
- TRYP by Wyndham Mall of Asia Manila
- Manila Prince Hotel
- City Garden Hotel Makati
- Kingsford Hotel Manila