Santa Ana

Antigua Guatemala

Iglesia de Nuestra Señora de Santa Ana, aldea Santa Ana en Antigua Guatemala.
Iglesia de Nuestra Señora de Santa Ana, aldea Santa Ana en Antigua Guatemala.

Popular places to visit

Panoramic inside the ruins of Antigua's Cathedral, one of the many buildings that collapsed after the earthquake that destroyed the city in 1773.

Antigua Guatemala Cathedral

After visiting Antigua Guatemala Cathedral, make a plan to see the other sights and activities in Antigua Guatemala. Discover the area's volcano viewpoints, or seek out its local tours.

Antigua Guatemala Cathedral
Antigua, Guatemala, volcano

Central Park

Enjoy the volcano viewpoints and explore Central Park, a lovely green space in Antigua Guatemala. Discover the area's shops, or seek out its local tours.

Central Park
Recent trip to Antigua, Guatemala.

Santa Catalina Arch

Find out about the history of Antigua Guatemala when you spend time at Santa Catalina Arch. Discover the volcano viewpoints and shops in this romantic area.

Santa Catalina Arch
Traditional vase and jar at market in Antigua, Guatemala.

Antigua Market

During your trip to Antigua Guatemala, you can enjoy retail therapy at Antigua Market. Discover the volcano viewpoints in this family-friendly area, or enjoy its local tours.

Antigua Market
A one of a kind facade

La Merced Church

After visiting La Merced Church, make a plan to see the other sights and activities in Antigua Guatemala. Discover the area's shops, or seek out its local tours.

La Merced Church
Cerro de la Cruz Antigua Guatemala

Cerro de La Cruz

You can find out about the history of Antigua Guatemala when you stop by Cerro de La Cruz. Discover the area's volcano viewpoints, or seek out its local tours.

Cerro de La Cruz

Things to do

Lake Atitlan One Day Tour from Antigua

Lake Atitlan One Day Tour from Antigua

￥14,240
per adult
80% of travellers recommend
Lake Atitlan One Day Tour from Antigua
Antigua: ATV Guided Sunset Tour

Antigua: ATV Guided Sunset Tour

￥10,061
per adult
100% of travellers recommend
Antigua: ATV Guided Sunset Tour
Viewpoint

Lake Atitlan Day Tour From Antigua

￥20,556
per adult
100% of travellers recommend
Lake Atitlan Day Tour From Antigua
Mold around 120g of chocolates

Bean-to-Bar Chocolate Workshop in ChocoMuseo Antigua

￥5,136
per adult
100% of travellers recommend
Bean-to-Bar Chocolate Workshop in ChocoMuseo Antigua
From Antigua: 2-Day Acatenango Volcano Hiking Tour with Food

From Antigua: 2-Day Acatenango Volcano Hiking with Guide

￥8,203
per adult
From Antigua: 2-Day Acatenango Volcano Hiking with Guide
Picture 5 for Activity From Antigua: Pacaya Volcano Trek

From Antigua: Pacaya Volcano Trek

￥3,637
per adult
92% of travellers recommend
From Antigua: Pacaya Volcano Trek
See all activities in Antigua Guatemala

Santa Ana Hotel Deals

Barceló Guatemala City

Barceló Guatemala City

4.5 out of 5
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
The price is ￥13,678 per night from Mar 2 to Mar 3
￥13,678
￥16,687 total
Mar 2 - Mar 3
includes taxes & fees
Book a stay at this luxury hotel in Guatemala City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the pool in our ...
9/10 Wonderful! (3,186 reviews)
Amenities and staff

Reviewed on Feb 11, 2026

Barceló Guatemala City
Porta Hotel Antigua

Porta Hotel Antigua

4.5 out of 5
8va Calle Poniente No1 Antigua Guatemala Sacatepequez
The price is ￥25,495 per night from Feb 18 to Feb 19
￥25,495
￥32,649 total
Feb 18 - Feb 19
includes taxes & fees
Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,005 reviews)
Excelente hotel

Reviewed on Feb 4, 2026

Porta Hotel Antigua
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

4.5 out of 5
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
The price is ￥41,100 per night from Feb 24 to Feb 25
￥41,100
￥52,027 total
Feb 24 - Feb 25
includes taxes & fees
Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,040 reviews)
Absolutely outstanding place. Loved it

Reviewed on Feb 8, 2026

Hotel Museo Spa Casa Santo Domingo
Wyndham Garden Guatemala City

Wyndham Garden Guatemala City

4 out of 5
1a Avenida 12-46 Zona 10 Guatemala City Guatemala
The price is ￥16,069 per night from Mar 8 to Mar 9
￥16,069
￥19,604 total
Mar 8 - Mar 9
includes taxes & fees
Book a stay at this business-friendly hotel in Guatemala City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,685 reviews)
Excellent staff

Reviewed on Feb 5, 2026

Wyndham Garden Guatemala City
Hotel Camino Real Antigua

Hotel Camino Real Antigua

4 out of 5
7a Calle Poniente 33B Antigua Guatemala Sacatepequez
The price is ￥24,074 per night from Feb 23 to Feb 24
￥24,074
￥34,396 total
Feb 23 - Feb 24
includes taxes & fees
Book a stay at this spa hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property ...
9.6/10 Exceptional! (1,000 reviews)
Great staff, comfortable and spacious room with lovely bathroom

Reviewed on Feb 2, 2026

Hotel Camino Real Antigua
Holiday Inn Guatemala City by IHG

Holiday Inn Guatemala City by IHG

3.5 out of 5
1a Avenida 13-22 Zona 10 Guatemala City Guatemala
The price is ￥16,842 per night from Mar 15 to Mar 16
￥16,842
￥20,547 total
Mar 15 - Mar 16
includes taxes & fees
Book a stay at this business-friendly hotel in Guatemala City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
9/10 Wonderful! (1,001 reviews)
Yes

Reviewed on Feb 8, 2026

Holiday Inn Guatemala City by IHG
See all 1,183 properties in Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Santa Ana

Cross and Volcan de Agua View From Cerro de la Cruz, Antigua, Sacatepequez Department, Guatemala

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Barrio de La Concepción
Vue du volcan de Fuego

Historic Center

While visiting Historic Center, you might make a stop by sights like Central Park and Santa Catalina Arch.

Historic Center

Santa Ana