Santa Ana

Panama City

Plaza Santa Ana, Panama Casco Viejo
View from the fish market
go there and eat fresh and yummy fish in all variations

Popular places to visit

Things to do


Santa Ana Hotel Deals

Casco View Apartments

Casco View Apartments

3.5 out of 5
C. 16 Oeste Panama City Provincia de Panamá
Book a stay at this business-friendly condo in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Cinta Costera ...
9/10 Wonderful! (78 reviews)
Honest review of apartments clean well organized minimalist, but with ok essentials in the kitchens, paper towels., few cleaning supplies look under sink., everything neat in and order. Large sliding glass window, but the view is of interesting neighborhood) ocean (window in bedroom is to hallway) ...

Reviewed on Mar 6, 2026

Casco View Apartments
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
The price is ¥24,898 per night from Mar 30 to Mar 31
¥24,898
¥27,388 total
Mar 30 - Mar 31
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (5,108 reviews)
Hotel is perfectly situated in the middle of the city, the hotel dos need some improvement as does look tired. Staff is amazing and the amenities are great. Breakfast is fantastic and service by the pool is also great.

Reviewed on Mar 17, 2026

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
The price is ¥22,097 per night from Apr 16 to Apr 17
¥22,097
¥24,307 total
Apr 16 - Apr 17
includes taxes & fees
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (2,485 reviews)
Room was OK. Close to airport which is convenient for a quick stay. TV was old and screen barely worked. Bartender tried to charge us almost $100 USD for 2 drinks. After I questioned they changed it to $20 so be sure to check your bill!

Reviewed on Mar 17, 2026

Crowne Plaza Panama Airport by IHG
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is ¥21,318 per night from Apr 5 to Apr 6
¥21,318
¥23,450 total
Apr 5 - Apr 6
includes taxes & fees
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,007 reviews)
El personal de servicio excelente muy amables y te ayudaban a encontrar lugares para visitar

Reviewed on Mar 16, 2026

Sheraton Grand Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
The price is ¥16,310 per night from Apr 5 to Apr 6
¥16,310
¥17,941 total
Apr 5 - Apr 6
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (1,005 reviews)
My stay here was really great. Close to everything, a safe area, wonderful happy friendly staff, awesome breakfast & the premises clean. I'll stay here again certainly.

Reviewed on Mar 15, 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
W Panama

W Panama

5 out of 5
Calle Aquilino de la Guardia & Calle 50 Panama City
Fully refundableReserve now, pay when you stay
The price is ¥31,667 per night from Mar 31 to Apr 1
¥31,667
¥34,834 total
Mar 31 - Apr 1
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy 2 restaurants, 3 hot tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,009 reviews)
The spa was amazing, I never went to a spa that washes your feet before a massage. What an amazing experience. Job well done. The hotel was so nice and our room omg just beautiful, we stayed in the supreme corner room and enjoyed every moment. Next time we have to stay a longer time because our 5 ...

Reviewed on Mar 16, 2026

W Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Santa Ana

View of the Panama City Old Town

Casco Viejo

4.5/5(178 area reviews)

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Casco Viejo
Balcony of a colonial house, Casco Viejo, Panama City, Panama, Central America

San Felipe

If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.

San Felipe
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El Chorrillo

While there might not be top attractions in El Chorrillo, you can explore the larger area and discover places like Albrook Shopping Mall and Maracana Stadium.

El Chorrillo
The skyline at Panama City, Panama. There are some nice walkways along the waterfront.

Calidonia

You might enjoy the shopping while in Calidonia. Cinta Costera is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.

Calidonia
The buses of Panama.

Balboa

The restaurants and shopping are a few reasons travelers visit Balboa. Though there aren't many top sights in the neighborhood, you can visit Albrook Shopping Mall and Flag of Cerro Ancón, a few notable attractions nearby.

Balboa
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Curundu

While Curundu isn't home to many top sights, Albrook Shopping Mall and Iglesia del Carmen are some notable places to visit nearby.

Curundu


Santa Ana