Plan a trip to see Calle 50

Price found within the past 48 hours. Click for updated prices.

Mahogany Suites

￥292,612

per person

Feb 3 - Feb 8

found 7 hours ago

Roundtrip non-stop flight included

Tokyo (HND) to Panama City (PTY)

10/10 Exceptional! (1 review)

Central Hotel Panama Casco Viejo

Casco Viejo

￥402,654

per person

Feb 3 - Feb 8

found 7 hours ago

Roundtrip non-stop flight included

Tokyo (HND) to Panama City (PTY)

9/10 Wonderful! (1,002 reviews)

Great location. Lovely lobby. Wonderful and abundant breakfast. Only drawback for us was our room -- it was a family room on the top floor and window was low, hard to see outside. Also a little loud from room next door.

Reviewed on Nov 30, 2025

Dreams Playa Bonita Panama - All Inclusive

￥399,948

per person

Feb 3 - Feb 8

found 7 hours ago

Roundtrip non-stop flight included

Tokyo (HND) to Panama City (PTY)

7.4/10 Good! (1,002 reviews)

Well situated, quiet location. Nice view, friendly staff.

Reviewed on Dec 2, 2025

Browse tours and tickets to explore Calle 50

Tours & day trips

See all 62 activities

City Sightseeing Panama City Hop-On Hop-Off Bus Tour

Free cancellation available

Adventure & outdoor

See all 26 activities

Day Tour in San Blas Islands All Included Visiting 4 Islands

Free cancellation available

Private & custom tours

See all 11 activities

PRIVATE NIGHT TOUR in Ciudad PANAMA + 360° POIN views

Free cancellation available

Cruises & boat tours

See all 8 activities

Panama Canal Partial Transit

Free cancellation available

Food, drink & nightlife

See all 3 activities

E-Tickets Emotions Dinner Theater Live Show Admission

Popular places to visit

Rainy day in Panama City but the charm of this city never ends. A beautiful rainbow over the city invites us to spend a bright day in paradise. #LifeAtExpedia

Multiplaza Pacific Mall

4.5/5(634 reviews)

During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Nice building, highlight on Panama's skyline.

Soho City Center

You can browse for the perfect souvenirs at Soho City Center during your stay in Panama City. Discover the area's shops, or seek out its local tours.

Cinta Costera a wonderful pedestrian walkway with a separate lane for bicyclists and skateboarders

#OrbitzTravel

Avenida Balboa

4/5(554 reviews)

You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.

Panama City skyline during the day #seetheworld

Uruguay Street

4/5(59 reviews)

During your visit to Panama City, you can do some window-shopping at Uruguay Street. While in this family-friendly area, you can savor the top-notch restaurants.