Santa Ana
Panama City
Visit Santa Ana
Stay near popular Santa Ana attractions
Things to do
Panama City: Zip Line Experience Over The City
￥6,404
per adult
94% of travellers recommend
From Panama City: Monkey Islands Tour on Gatun Lake
￥4,803
per adult
94% of travellers recommend
Half day of Panama city and canal tour: shared and private
￥10,673
per adult
96% of travellers recommend
Panama Canal: The Most Complete Wildlife Experience
￥7,684
per adult
98% of travellers recommend
San Blas Island-Hopping : Full-Day Adventure from Panama City
￥21,361
per adult
Panama City: Poin Full Package Experience
￥24,814
per adult
98% of travellers recommend
Santa Ana Hotel Deals
Hotel Caracas - Casco Viejo
Plaza De Santa Ana Panama City Provincia di Panama
The price is ￥5,678 per night from Sep 23 to Sep 24
￥5,678
￥6,276 total
Sep 23 - Sep 24
includes taxes & fees
Stay at this hotel in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Cinta Costera ...
8.4/10 Very Good! (9 reviews)
"I would not recommend this hotel to anyone looking for a nice comfortable room. At first we wanted to check it out for some student groups we manage in Panama. And although from the outside and upon arrival the hotel looked fine, after some interactions with the staff it became evident that customer ..."
Reviewed on Sep 7, 2026
Casco View Apartments
C. 16 Oeste Panama City Provincia de Panamá
The price is ￥8,633 per night from Sep 8 to Sep 9
￥8,633
￥14,184 total
Sep 8 - Sep 9
includes taxes & fees
Book a stay at this business-friendly condo in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Albrook Shopping ...
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
The price is ￥19,207 per night from Sep 28 to Sep 29
￥19,207
￥21,128 total
Sep 28 - Sep 29
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (5,943 reviews)
"The hotel is aging and in Panamá humidity is a major factor. We stayed for 2 consecutive weekends. Last weekend there was a mold damp smell and this weekend there was an overpowering of perfume in the building. As if they tried to block out the mold smell. It made it difficult to breath."
Reviewed on Sep 7, 2026
Central Hotel Panama Casco Viejo
Plaza de la Independencia Casco Viejo Panama City Panama
The price is ￥28,658 per night from Oct 6 to Oct 7
￥28,658
￥31,524 total
Oct 6 - Oct 7
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
The price is ￥19,689 per night from Oct 6 to Oct 7
￥19,689
￥22,690 total
Oct 6 - Oct 7
includes taxes & fees
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (2,716 reviews)
"Very convenient location near the airport. It was perfect for a one-night transit stay—easy, practical, and reasonably priced."
Reviewed on Sep 7, 2026
Dreams Playa Bonita Panama - All Inclusive
KM 7, Road to Veracruz Veracruz Panama
The price is ￥43,487 per night from Oct 1 to Oct 2
￥43,487
￥43,487 total
Oct 1 - Oct 2
includes taxes & fees
Book a stay at this beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.8/10 Good! (1,074 reviews)
"Resort is definitely not 5 star. 2-3 star at best. Better options!"
Reviewed on Sep 7, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Santa Ana
Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.
Casco Viejo
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
Photo by My World
Open Photo by My World
Bella Vista
Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.
El Cangrejo
The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.
San Francisco
San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.
Calidonia
You might enjoy the shopping while in Calidonia. Via Espana is a notable sight, and you can get around town at Lotería Station or Santo Tomás Station to see more of the city.
