Find hotels in Saint James City, FL from ￥11,552

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Dec 14 - Dec 15
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Our top choices for Saint James City hotels

Exterior
Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
2.5 star property
Saint James City
9.6 out of 10, Exceptional, (144)
"great boutique hotel in an amazing area on Pine Island Fl. Great restaurants and bars walkable and great fishing. "
United States
Pat
The price is ￥28,138
￥36,586 total
includes taxes & fees
Dec 17 - Dec 18
Off the Charts Inn & Out Island Resort
Exterior
Kona Kai Motel

Kona Kai Motel

Kona Kai Motel
Mid Island
9.0 out of 10, Wonderful, (941)
"Spacious rooms, friendly staff, quiet surroundings."
United States
James
The price is ￥24,774
￥28,453 total
includes taxes & fees
Dec 15 - Dec 16
Kona Kai Motel
Room, 1 King Bed | Down comforters, iron/ironing board, free WiFi, bed sheets
Boca Grande Hotel

Boca Grande Hotel

Boca Grande Hotel
2.5 star property
Boca Grande
8.8 out of 10, Excellent, (584)
"This place was awesome!"
United States
Dharyl
The price is ￥21,034
￥23,558 total
includes taxes & fees
Dec 15 - Dec 16
Boca Grande Hotel
Lobby
Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers
3.0 star property
Hancock
9.4 out of 10, Exceptional, (743)
"Nice hotel "
United States
Decoste
The price is ￥20,411
￥22,759 total
includes taxes & fees
Dec 16 - Dec 17
Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers
View from room
Matlacha on Shoreview

Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
Cape Coral
9.6 out of 10, Exceptional, (210)
"Place was great. Nice and neat perfect for what i needed."
United States
Michael
The price is ￥7,011
￥18,241 total
includes taxes & fees
Dec 15 - Dec 16
Matlacha on Shoreview
Outdoor pool, open 8:00 AM to 10:00 PM, cabanas (surcharge)
The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
Pelican
9.0 out of 10, Wonderful, (1003)
"Excellent stay over Thanksgiving holiday!"
United States
Nicole
The price is ￥22,792
￥31,334 total
includes taxes & fees
Dec 21 - Dec 22
The Westin Cape Coral Resort At Marina Village
Free buffet breakfast
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
Caloosahatchee
9.4 out of 10, Exceptional, (1040)
"Hotel was very clean and the breakfast had a great variety."
United States
Lynn
The price is ￥17,607
￥19,633 total
includes taxes & fees
Dec 21 - Dec 22
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Terrace/patio
Dolphin Key Resort

Dolphin Key Resort

Dolphin Key Resort
3.0 star property
Caloosahatchee
8.8 out of 10, Excellent, (1205)
"Very nice staff, great shower set up, the on site restaurant was very good. "
United States
Chuck
The price is ￥15,581
￥17,373 total
includes taxes & fees
Dec 15 - Dec 16
Dolphin Key Resort
Exterior
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
Caloosahatchee
8.6 out of 10, Excellent, (1002)
"The rooms were clean, staff were very friendly and accommodating."
United States
Sandra
The price is ￥14,833
￥16,538 total
includes taxes & fees
Dec 21 - Dec 22
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
Lobby
Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa
3.0 star property
Captiva
8.6 out of 10, Excellent, (1001)
"Stunning Beach View great Staff "
United States
Robert
The price is ￥49,206
￥60,318 total
includes taxes & fees
Dec 21 - Dec 22
Tween Waters Island Resort & Spa
Balcony view
OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
2.5 star property
Caloosahatchee
5.8 out of 10, (1004)
"Beautiful place "
United States
Blaine
The price is ￥11,773
￥14,218 total
includes taxes & fees
Dec 15 - Dec 16
OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
3 outdoor pools, cabanas (surcharge), pool umbrellas
South Seas Resort

South Seas Resort

South Seas Resort
3.5 star property
Captiva
8.4 out of 10, Very Good, (1001)
"Fantastic place for perfect relaxation, hammocks are placed perfectly for a tropical feel staff is outstanding customer service. A top of the cap to Jeff and Anthony at the front desk."
United States
John
South Seas Resort
Outdoor pool
Sanibel Island Beach Resort

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island
9.2 out of 10, Wonderful, (1466)
"The resort was very clean and the staff were all friendly. It was an excellent stay"
United States
Zachary
The price is ￥32,238
￥39,841 total
includes taxes & fees
Dec 15 - Dec 16
Sanibel Island Beach Resort
2 outdoor pools, cabanas (surcharge), pool umbrellas
Sundial Beach Resort & Spa

Sundial Beach Resort & Spa

Sundial Beach Resort & Spa
5.0 star property
Mid Island
8.6 out of 10, Excellent, (2584)
"wonderful family friendly and spotless resort"
United States
Mary Anne
The price is ￥61,546
￥77,136 total
includes taxes & fees
Dec 15 - Dec 16
Sundial Beach Resort & Spa
Luxury Suite, Sea View | Beach/ocean view
Island Inn

Island Inn

Island Inn
3.5 star property
West End
9.4 out of 10, Exceptional, (1122)
"Really nice, updated, and clean room with a screened waterfront balcony in a perfect place on the island (far enough away from the big resorts to be in a quieter area, but close enough to the center area of the island to be convenient). "
United States
Chris
The price is ￥32,564
￥36,309 total
includes taxes & fees
Dec 16 - Dec 17
Island Inn
Exterior
Sanibel Inn

Sanibel Inn

Sanibel Inn
3.0 star property
East End
9.0 out of 10, Wonderful, (1000)
"Very nice hotel/resort. Clean, quiet, nice pool, attentive staff. Love the screened in balcony. "
Canada
Jonathan
The price is ￥43,757
￥57,823 total
includes taxes & fees
Dec 16 - Dec 17
Sanibel Inn
1 bedroom, desk, laptop workspace, iron/ironing board
SpringHill Suites by Marriott Fort Myers Estero

SpringHill Suites by Marriott Fort Myers Estero

SpringHill Suites by Marriott Fort Myers Estero
2.5 star property
Estero
9.2 out of 10, Wonderful, (819)
"Great customer service, very clean, beautiful room, great breakfast "
United States
emma
The price is ￥20,411
￥23,537 total
includes taxes & fees
Dec 21 - Dec 22
SpringHill Suites by Marriott Fort Myers Estero
Exterior
Tarpon Tale Inn

Tarpon Tale Inn

Tarpon Tale Inn
3.0 star property
East End
9.6 out of 10, Exceptional, (392)
"Great staff, close to the beach. Provided beach chairs, umbrella, & beach cart for stay. Highly recommend"
United States
Thomas
The price is ￥26,332
￥29,361 total
includes taxes & fees
Dec 17 - Dec 18
Tarpon Tale Inn
BBQ/picnic area
Embassy Suites by Hilton Fort Myers Estero

Embassy Suites by Hilton Fort Myers Estero

Embassy Suites by Hilton Fort Myers Estero
3.5 star property
Estero
9.2 out of 10, Wonderful, (1058)
"Loved the breakfast and nightly drinks provided by the hotel. Rooms were spacious and clean and provided a great landing spot during our trip. "
United States
Kerry
The price is ￥20,068
￥22,376 total
includes taxes & fees
Dec 23 - Dec 24
Embassy Suites by Hilton Fort Myers Estero
Property amenity
TownePlace Suites by Marriott Fort Myers Estero

TownePlace Suites by Marriott Fort Myers Estero

TownePlace Suites by Marriott Fort Myers Estero
3.5 star property
Estero
9.4 out of 10, Exceptional, (462)
"Clean room and very nice staff"
United States
Nancy
The price is ￥23,527
￥26,233 total
includes taxes & fees
Dec 24 - Dec 25
TownePlace Suites by Marriott Fort Myers Estero
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Saint James City

Find the best Saint James City areas and neighborhoods for the activities you enjoy most. Learn more about Saint James City
Learn more about Saint James City

Manatee Bay

Plan a visit to nearby attractions like Harbour View Gallery while you're exploring Manatee Bay and the larger area.

Learn more about Saint James City

Rent a boat to explore Pine Island's mangrove-lined waterways where dolphins often play alongside fishing enthusiasts. Savor fresh-caught seafood at waterfront restaurants while watching spectacular Gulf Coast sunsets that paint the sky in vibrant colors.

See all hotels in Saint James City
Sunset on the southern end of Pine Island, Florida.

Top Saint James City Hotel Reviews

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

10/10 Excellent
"Friendly and accommodating staff, great breakfast selection, nicely-maintained pool, located across the street from many good local restaurants."
Brendan Michael 10-night trip
Posted 3 days ago
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

More cheap stays in Saint James City

Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

4850 S Cleveland Ave Fort Myers FL
The price is ￥10,361 per night from Dec 31 to Jan 1
￥10,361
￥11,552 total
Dec 31 - Jan 1, 2026
includes taxes & fees
6.6/10 (1,002 reviews)

Frequently asked questions

Where is the best place for a stay in Saint James City?
Based on Expedia's traveler preferences, Off the Charts Inn & Out Island Resort is a top place to stay in Saint James City. Two other choices for your stay in the area are Margaritaville Beach Resort Fort Myers and Lani Kai Beachfront Resort. See all available top hotels, or vacation rentals in Saint James City.
What are some of the best vacation rentals in Saint James City?
Luxury family friendly WATERFRONT home with a POOL, PLAYGROUND, FIREPIT & BEACH: This vacation home rental near Saint James City is equipped with a barbecue grill, air-conditioning, and laundry facilities to help you feel comfortable during your stay. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in Saint James City.
If I need to cancel my hotel reservation in Saint James City, will I receive a refund?
Yes! The majority of room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to still cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Saint James City.
Where can I learn more about changing or cancelling my trip to Saint James City?
For more information about updating your trip to Saint James City or cancelling it, go to https://www.expedia.com/service/.
What's the best pet-friendly place to stay in Saint James City?
Off the Charts Inn & Out Island Resort is a top pet-friendly option for your stay. Two other good options for you and your pet include Off the Charts Inn - Queen Double Room and Off the Charts Inn King Efficiency. See more pet-friendly hotel accommodations in Saint James City.
What are some hotels with pools in Saint James City?
Margaritaville Beach Resort Fort Myers: Hotel located near Key West Express. Offers 4 restaurants, an outdoor pool, and a full-service spa. Lani Kai Beachfront Resort and Hyatt Vacation Club at Coconut Cove, Bonita Springs are a couple of other choices that offer an onsite pool. View all hotels with pools in Saint James City.
What's the best place to stay near Southwest Florida International Airport (RSW)?
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park is one of the top choices for your stay and is a popular hotel, featuring free breakfast and an outdoor pool. It's located 2.5 mi (4 km) from Southwest Florida Intl. Airport. Other options close to the airport include La Quinta Inn & Suites by Wyndham Fort Myers Airport and Baymont by Wyndham Fort Myers Airport.
What's it like to stay in Saint James City?
Visitors can enjoy all that Saint James City has to offer including its seafood restaurants. Tourists to the city can also enjoy its relaxing setting. A top sight in the area is Key West Express. In Saint James City, there are 194 hotels and other accommodations to choose from. Find out more about Saint James City.
What are the top places to visit in Saint James City?
Key West Express is a notable place to visit in the area. You'll also find J. N. Ding Darling National Wildlife Refuge and Dunes Golf and Tennis Club in the area. Check out what more to see and do in Expedia's Saint James City guide.
What's the seasonal weather like in Saint James City?
The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 68°F. The rainiest months in Saint James City are August, June, September, and July, with each month seeing an average of 7 inches of rainfall.

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