A marina with boats docked, a house, and palm trees.

Find hotels in Saint James City, FL from ļæ„9,006

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Saint James City hotels

A balcony with a wooden table and chairs, a hanging chair, and a view of palm trees and a pool.

1. Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
2.5 star property
Saint James City
9.6 out of 10, Exceptional, (164 reviews)
"Very comfortable and convenient location!"
United States
Lisa
The price is ļæ„26,617
ļæ„34,956 total
includes taxes & fees
Nov 4 - Nov 5
Off the Charts Inn & Out Island Resort
A beach with a variety of seashells and pebbles.

2. Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island
9.2 out of 10, Wonderful, (2,388 reviews)
"Love this place - always have a nice time here -"
United States
Pablo
The price is ļæ„31,396
ļæ„39,406 total
includes taxes & fees
Nov 1 - Nov 2
Sanibel Island Beach Resort
A waterfront hotel with multiple buildings, a dock, and a calm body of water reflecting the structures.

3. Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
Punta Rassa
8.6 out of 10, Excellent, (1,000 reviews)
"I love everything about this hotel"
United States
Yunior
The price is ļæ„32,690
ļæ„41,971 total
includes taxes & fees
Nov 12 - Nov 13
Marriott Sanibel Harbour Resort & Spa
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

4. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
Caloosahatchee
9.4 out of 10, Exceptional, (1,731 reviews)
"Excellent hotel if you want to stay there for a few days"
United States
Gabriel
The price is ļæ„15,777
ļæ„17,592 total
includes taxes & fees
Nov 2 - Nov 3
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
A balcony with a table and chairs, large windows, and a view of the sea.

5. The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
Pelican
9.0 out of 10, Wonderful, (1,001 reviews)
"Very clean and nice place!"
United States
Charles
The price is ļæ„23,079
ļæ„32,770 total
includes taxes & fees
Nov 15 - Nov 16
The Westin Cape Coral Resort At Marina Village
A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

6. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
Fort Myers
8.2 out of 10, Very good, (1,396 reviews)
"The staff was very helpful during my stay."
United States
Samantha
The price is ļæ„13,276
ļæ„14,803 total
includes taxes & fees
Nov 1 - Nov 2
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
A large, clear swimming pool with multiple lounge areas and palm trees.

7. Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers
4.0 star property
Fort Myers Beach
9.0 out of 10, Wonderful, (2,715 reviews)
"Our favorite place to stay."
United States
Anastasia
The price is ļæ„26,686
ļæ„37,671 total
includes taxes & fees
Nov 1 - Nov 2
Margaritaville Beach Resort Fort Myers
A modern living room with a TV, dining table, and chairs. There is a balcony with a view of palm trees.

8. Casa Ybel Resort

Casa Ybel Resort
2.5 star property
Mid Island
8.8 out of 10, Excellent, (472 reviews)
"Hotel was amazing!!"
United States
Yesenia
The price is ļæ„40,915
ļæ„45,619 total
includes taxes & fees
Oct 30 - Oct 31
Casa Ybel Resort
A pathway leading to a pool area with lounge chairs and umbrellas, surrounded by tropical plants and a thatched-roof structure.

9. Sanibel Inn

Sanibel Inn
3.0 star property
East End
9.2 out of 10, Wonderful, (1,000 reviews)
"Staff was amazingly friendly"
United States
Tamara
The price is ļæ„46,402
ļæ„61,766 total
includes taxes & fees
Nov 29 - Nov 30
Sanibel Inn
A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

10. Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
Fort Myers
8.8 out of 10, Excellent, (1,000 reviews)
"The hotel was in a great location, very clean and had great breakfast options."
United States
jennifer
The price is ļæ„14,199
ļæ„15,831 total
includes taxes & fees
Nov 1 - Nov 2
Residence Inn by Marriott Fort Myers Sanibel
A swimming pool with a rock arch structure, a multi-story building with balconies, and palm trees in the background.

11. Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
Fort Myers Beach
9.4 out of 10, Exceptional, (1,488 reviews)
"It's nice place to stay"
United States
Mario
The price is ļæ„32,882
ļæ„47,043 total
includes taxes & fees
Nov 29 - Nov 30
Pink Shell Beach Resort and Marina
A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.

12. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
3.0 star property
Fort Myers Beach
8.8 out of 10, Excellent, (1,000 reviews)
"One of the best properties Iā€™ve stayed in and the staff were excellent."
United States
Christina
The price is ļæ„14,370
ļæ„16,022 total
includes taxes & fees
Oct 31 - Nov 1
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
A beach with a view of the ocean and a sunset.

13. Island Inn

Island Inn
3.5 star property
West End
9.4 out of 10, Exceptional, (1,165 reviews)
"Great location"
United States
Nicole
The price is ļæ„31,906
ļæ„35,575 total
includes taxes & fees
Nov 1 - Nov 2
Island Inn
An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

14. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
Fort Myers Beach
9.2 out of 10, Wonderful, (1,000 reviews)
"Clean Hotel! Convenient for one night stay, close to airport and beaches."
United States
Kimberly
The price is ļæ„14,617
ļæ„16,299 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
A pool area with lounge chairs and umbrellas, a beach with umbrellas and lounge chairs, and palm trees.

15. Sundial Beach Resort & Spa

Sundial Beach Resort & Spa
5.0 star property
Mid Island
8.6 out of 10, Excellent, (2,717 reviews)
"Love the resort and great access to beach"
United States
Lisa Renee
The price is ļæ„48,711
ļæ„64,692 total
includes taxes & fees
Nov 10 - Nov 11
Sundial Beach Resort & Spa
A beachfront hotel with a pool, beach, and ocean view.

16. DiamondHead Beach Resort

DiamondHead Beach Resort
3.5 star property
Fort Myers Beach
9.2 out of 10, Wonderful, (1,325 reviews)
"excellent place will stay again!"
United States
James Edward
The price is ļæ„27,638
ļæ„36,974 total
includes taxes & fees
Nov 18 - Nov 19
DiamondHead Beach Resort
A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a stone archway.

17. The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites
3.0 star property
Fort Myers Beach
8.6 out of 10, Excellent, (1,841 reviews)
"excellent place to stay"
United States
Shayne
The price is ļæ„12,708
ļæ„17,325 total
includes taxes & fees
Nov 2 - Nov 3
The Lighthouse Resort Inn & Suites
A balcony with wicker furniture, a view of a beach, and a clear sky.

18. Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
Fort Myers Beach
8.8 out of 10, Excellent, (2,155 reviews)
"It was great to be right on the beach! The restaurants were also good."
United States
Tanya
The price is ļæ„17,763
ļæ„23,325 total
includes taxes & fees
Nov 3 - Nov 4
Lani Kai Beachfront Resort
A beach view from a balcony with a pool, palm trees, and a building with a balcony.

19. Edison Beach House

Edison Beach House
3.5 star property
Fort Myers Beach
9.4 out of 10, Exceptional, (1,958 reviews)
"One of the best locations on Ft Myers Beach"
United States
mark
The price is ļæ„28,398
ļæ„37,820 total
includes taxes & fees
Oct 30 - Oct 31
Edison Beach House
A modern dining area with a central island, multiple tables, and chairs.

20. Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers
3.0 star property
Hancock
9.4 out of 10, Exceptional, (914 reviews)
"The hotel was very clean and breakfast had a lot of variety"
United States
Mauricio
The price is ļæ„17,299
ļæ„19,288 total
includes taxes & fees
Nov 22 - Nov 23
Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Where to stay in Saint James City

Find the best Saint James City areas and neighborhoods for the activities you enjoy most. Learn more about Saint James City
Learn more about Saint James City

Manatee Bay

While there might not be top attractions in Manatee Bay, you can explore the larger area and discover places like Harbour View Gallery and Rumrunners.

Learn more about Saint James City

Rent a boat to explore Pine Island's mangrove-lined waterways where dolphins often play alongside fishing enthusiasts. Savor fresh-caught seafood at waterfront restaurants while watching spectacular Gulf Coast sunsets that paint the sky in vibrant colors.

See all hotels in Saint James City
A wooden sign with 'Pine Island' and 'I live where you vacation' written on it, overlooking a body of water with palm trees and houses in the background.
Photo by Stephanie Karasek
Open Photo by Stephanie Karasek

Top Saint James City Hotel Reviews

Sanibel Island Beach Resort

Sanibel Island Beach Resort

10/10 Excellent
"This was our first trip to Sanibel Island and and it did not disappoint! The rooms were clean. We had easy access to the beach, 2 minutes walk, the beach chairs were already on the beach and waiting. Everyone was so accommodating and friendly. It was such a relaxing atmosphere. The Tiki bar was amazing! Our bartender made us an old fashion and a strawberry daiquiri that was spot on. The on sight restaurant was fantastic. The burgers were delicious, but the fish and chips were good as well. Our breakfast was egg, ham and cheese bagel with a carmel and a mocha frappe... in one word it was delicious! The shelling was so much fun and was not a disappointment. We certainly will be returning!!"
Joyce 2-night trip
Posted less than an hour ago
Sanibel Island Beach Resort

More cheap stays in Saint James City

Quality Inn Fort Myers Cape Coral

Quality Inn Fort Myers Cape Coral

4760 S Cleveland Ave Fort Myers FL
The price is ļæ„7,204 per night from Nov 22 to Nov 23
ļæ„7,204
ļæ„9,006 total
Nov 22 - Nov 23
includes taxes & fees

Frequently asked questions

Where is the best place for a stay in Saint James City?
Baymont by Wyndham Fort Myers Central, located 14.3 mi (23 km) from the heart of Saint James City, is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are Margaritaville Beach Resort Fort Myers and Lani Kai Beachfront Resort. See all available top hotels, or vacation rentals in Saint James City.
What are some of the best vacation rentals in Saint James City?
šŸ”†šŸLITTLE PARADISEšŸšŸ”†: This highly rated vacation home rental in Saint James City is located by the ocean and has a fireplace, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a selection of games and a hot tub. See all vacation rentals in Saint James City.
If I need to cancel my hotel reservation in Saint James City, will I receive a refund?
Yes! The majority of room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to still cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Saint James City.
Where can I learn more about changing or cancelling my trip to Saint James City?
For more information about updating your trip to Saint James City or cancelling it, go to https://www.expedia.com/service/.
What's the best pet-friendly place to stay in Saint James City?
Off the Charts Inn & Out Island Resort is a top pet-friendly option for your stay. Two other good options for you and your pet include Off the Charts Inn - Queen Double Room and Off the Charts Inn - King Suite. See more pet-friendly hotel accommodations in Saint James City.
What are some hotels with pools in Saint James City?
Baymont by Wyndham Fort Myers Central: Hotel located near Edison and Ford Winter Estates. Features daily, an outdoor pool, and free self parking. Margaritaville Beach Resort Fort Myers and Lani Kai Beachfront Resort are a couple of other choices that offer an onsite pool. View all hotels with pools in Saint James City.
What's the best place to stay near Southwest Florida International Airport (RSW)?
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park is one of the top choices for your stay and is a popular hotel, featuring free breakfast and an outdoor pool. It's located 2.5 mi (4 km) from Southwest Florida Intl. Airport. Other options close to the airport include La Quinta Inn & Suites by Wyndham Fort Myers Airport and Baymont by Wyndham Fort Myers Airport.
What's it like to stay in Saint James City?
Visitors can enjoy all that Saint James City has to offer including its seafood restaurants. Tourists to the city can also enjoy its relaxing setting. A top sight in the area is Key West Express. In Saint James City, there are 202 hotels and other accommodations to choose from. Find out more about Saint James City.
What are the top places to visit in Saint James City?
Key West Express is a notable place to visit in the area. You'll also find J. N. Ding Darling National Wildlife Refuge and Periwinkle Way in the area. Check out what more to see and do in Expedia's Saint James City guide.
What's the seasonal weather like in Saint James City?
The hottest months are usually August and July with an average temp of 83Ā°F, while the coldest months are January and February with an average of 68Ā°F. The rainiest months in Saint James City are August, June, September, and July, with each month seeing an average of 7 inches of rainfall.

Explore a world of travel with Expedia