Top 10 Hotels in Perryville, MO from ￥12,111 - Competitive Prices

A train crossing a stone bridge over a river, surrounded by lush greenery.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Perryville

Cabin

Family friendly

Pool

Hot tub

Pet friendly

Cottage

Waterpark

Apartment

Condo

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Perryville hotels

Breakfast included

Pet friendly

Hotel

Reserve now, pay later

Motel

In-room safe, desk, blackout drapes, soundproofing

1. Holiday Inn Express & Suites Perryville by IHG

Perryville

Jacalyn

￥15,454

￥17,691 total

includes taxes & fees

Sep 6 - Sep 7

2. Perryville RV Resort

Perryville

Von

￥10,579

￥12,111 total

includes taxes & fees

Aug 18 - Aug 19

Suite, 1 King Bed, Non Smoking (1 Bedroom) | In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible) | In-room safe, desk, laptop workspace, blackout drapes

3. Super 8 by Wyndham Perryville

Perryville

Angela

￥10,698

￥12,247 total

includes taxes & fees

Sep 15 - Sep 16

4. The Atrium - A Boutique Hotel

Perryville

Brian

￥12,045

￥25,421 total

includes taxes & fees

Aug 17 - Aug 18

5. Days Inn by Wyndham Perryville

Perryville

Wanda

￥10,754

￥12,309 total

includes taxes & fees

Aug 17 - Aug 18

Iron/ironing board, rollaway beds (free), WiFi (free), bed sheets

6. Quality Inn Perryville I-55

Perryville

Evelynmaryeka

￥10,746

￥12,301 total

includes taxes & fees

Sep 1 - Sep 2

7. The Mediterranean House 1858

Perryville

￥77,355

￥126,720 total

includes taxes & fees

Aug 24 - Aug 25

Coffee/tea maker, full-size fridge, microwave, oven

Urban Loft 1 | Egyptian cotton sheets, premium bedding, down comforters

55-inch Smart TV with digital channels, TV, streaming services

8. Urban Lofts

Perryville

Grace

￥32,119

￥49,549 total

includes taxes & fees

Aug 17 - Aug 18

Desk, laptop workspace, blackout drapes, iron/ironing board

9. Drury Inn & Suites Jackson MO

Jackson

Jamie

￥12,744

￥13,474 total

includes taxes & fees

Aug 23 - Aug 24

Deluxe Studio Suite, 1 King Bed, Non Smoking | Jetted tub

Deluxe Studio Suite, 1 King Bed, Non Smoking | Bathroom | Hair dryer, towels

10. Baymont by Wyndham Chester IL

Chester

Doug

￥11,614

￥12,890 total

includes taxes & fees

Aug 30 - Aug 31

Hypo-allergenic bedding available, desk, laptop workspace

11. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Kevin

￥13,407

￥14,510 total

includes taxes & fees

Aug 19 - Aug 20

In-room safe, desk, iron/ironing board, WiFi (free)

12. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Murphysboro

Sarah

￥18,162

￥20,157 total

includes taxes & fees

Aug 23 - Aug 24

Premium bedding, desk, laptop workspace, blackout drapes

13. Microtel Inn & Suites by Wyndham Sainte Genevieve

Ste Genevieve

Samantha

￥13,191

￥15,512 total

includes taxes & fees

Sep 6 - Sep 7

Standard room, 2 double beds. | Blackout drapes, soundproofing, iron/ironing board (on request)

Standard room , 1 King bed. | Blackout drapes, soundproofing, iron/ironing board (on request)

14. Triangle Inn Motel

Ste Genevieve

Pamela

￥10,969

￥12,901 total

includes taxes & fees

Aug 17 - Aug 18

1 bedroom, desk, iron/ironing board, WiFi (free)

15. Comfort Suites Jackson-Cape Girardeau

Jackson

VICTORIA

￥13,354

￥14,452 total

includes taxes & fees

Sep 14 - Sep 15

16. Tru By Hilton Cape Girardeau

Cape Girardeau

Gwendolyn

￥14,240

￥16,208 total

includes taxes & fees

Aug 23 - Aug 24

Standard Room, 2 Double Beds | Desk, iron/ironing board, WiFi (free), bed sheets

17. Madison Inn Lodge

Fredericktown

Christine

￥13,942

￥15,229 total

includes taxes & fees

Aug 17 - Aug 18

Desk, iron/ironing board, WiFi (free), bed sheets

Free toiletries, hair dryer (on request), towels

18. Sparta Motel Near St. Louis / Mississippi River IL

Sparta

Stacey

￥11,152

￥13,492 total

includes taxes & fees

Aug 17 - Aug 18

New Orleans Room | WiFi (free), bed sheets

Mississippi Room | WiFi (free), bed sheets

19. The Conner House B&B

Prairie du Rocher

James

￥24,894

￥27,628 total

includes taxes & fees

Aug 17 - Aug 18

Classic Room, 1 King Bed | Down comforters, desk, laptop workspace, blackout drapes

Classic Room, 1 King Bed | Bathroom | Free toiletries, hair dryer, towels, soap

20. Briarwood Inn of Sparta

Sparta

Steve

￥12,586

￥13,967 total

includes taxes & fees

Aug 24 - Aug 25

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Perryville attractions

National Shrine of Our Lady of the Miraculous Medal

8.8/10 (19 reviews)

This serene Catholic shrine honors the Miraculous Medal with exquisite stained glass and intricate murals. Visitors find spiritual renewal along the peaceful Rosary Walk and Marian Grotto gardens.

See properties

Saint Marys Lake

Saint Marys Lake offers a tranquil escape in Missouri's countryside with serene waters reflecting the changing seasons. Bring a picnic and binoculars to spot local wildlife while enjoying this peaceful local reservoir.

See properties

Perryville Country Club

6.6/10 (7 reviews)

This classic 9-hole course features Zoysia fairways and Bent grass greens dating back to 1932. Enjoy a challenging round followed by refreshments at the clubhouse overlooking the scenic Missouri landscape.

See properties

Missouri's National Veterans Memorial

9.2/10 (14 reviews)

This full-scale replica of the Vietnam Veterans Memorial offers a profound space for reflection away from Washington D.C. Walk the black granite wall inscribed with 58,000 names in Missouri's countryside.

See properties

County Lake State Wildlife Management Area

This peaceful 103-acre reservoir offers exceptional fishing for largemouth bass, bluegill, and hybrid striped bass. Cast your line near brush piles and vegetation beds for the best chance at a memorable catch.

See properties

James M. Eddleman Millitary Museum

This veteran-founded museum honors military service through authentic Vietnam War artifacts and personal stories. Explore Jim Eddleman's collection and experience history through the eyes of those who lived it.

See properties

Feltz Street Park

This community park features a gentle 0.41-mile loop trail and pickleball court. Bring your own equipment and enjoy this peaceful local spot during spring or fall for the best outdoor experience.

See properties

Perryville City Hall

Perryville City Hall serves as the administrative heart of this Missouri town, housing essential government offices. Visit during weekday business hours to access city services or attend public meetings.

See properties

Perryville and related destinations

Historic battlefields and the charming downtown district tell stories of Missouri's Civil War past. Visit Perry County Heritage Tourism Center and enjoy local wineries along the Mississippi Hills Wine Trail for a perfect weekend.

See all hotels in Perryville

Top Perryville Hotel Reviews

Baymont by Wyndham Chester IL

10/10 Excellent

"I have a wonderful stay here for a week. The restroom, room are clean and bed was comfortable. I got good rest every day there."

Drury Inn & Suites Jackson MO

10/10 Excellent

"The staff was all very helpful and considerate breakfast was delicious. The hors d’oeuvres and drinks are very good. My kids had a great time in the swimming pool. This is a place. I will definitely stay again."

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

8/10 Good

"The staff for breakfast was wonderful. The hotel was fully booked. The staff was able to keep up with the demand of food. Our room did not look like it had been cleaned. There was food on floor and on pull out couch. The sheets had stains on them. Unfortunately with them being fully there wasn't much they could do. We did check in around 10pm and front desk person did offer to clean it. The housekeeping was supposed to clean it next morning. Unfortunately the only thing they did was pick up dirty and replace with clean ones."

Tru By Hilton Cape Girardeau

10/10 Excellent

"Clean"

Microtel Inn & Suites by Wyndham Sainte Genevieve

8/10 Good

"The Breakfast items were a bit stale. Staff was not super helpful."

Perryville RV Resort

10/10 Excellent

"Great time"

Super 8 by Wyndham Perryville

10/10 Excellent

"Super 8 is my go to when I need to get a room."

New! Luxury Meets Nature - TreeRise at BaseCamp

10/10 Excellent

"Everything beat my expectations! From making initial reservations, to host communication, to the amazing property. Everything was absolutely wonderful. My wife and I will definitely go back to the TreeRise again in the future!!"

Silo Farm Haus- located in the heart of wine country!

10/10 Excellent

"Our stay at the Silo House was absolutely wonderful! The home and surrounding property are stunning, and the peaceful setting made it the perfect escape from the hustle and bustle of everyday life. If you’re looking for a place to truly relax and recharge, this is it.My favorite part of the entire stay was starting each morning on the porch swing, watching the sunrise while listening to the sounds of nature. It was such a calming and memorable experience.The house itself was immaculate and thoughtfully equipped with every amenity you could possibly need. It was clear that every detail had been considered to make guests feel comfortable and at home.We couldn’t have asked for a better getaway and would absolutely stay here again. Highly recommend the Silo House to anyone looking for a peaceful, beautiful retreat!"

More cheap stays in Perryville

Super 8 by Wyndham Perryville

1119 Vincent Dr Perryville MO

￥10,698

￥12,247 total

Sep 15 - Sep 16

includes taxes & fees

8.4/10 Very Good! (1,001 reviews)

Baymont by Wyndham Chester IL

2150 State Street Chester IL

￥11,614

￥12,890 total

Aug 30 - Aug 31

includes taxes & fees

8.4/10 Very Good! (415 reviews)

Microtel Inn & Suites by Wyndham Sainte Genevieve

21958 Hwy 32 Ste Genevieve MO

￥13,191

￥15,512 total

Sep 6 - Sep 7

includes taxes & fees

8.8/10 Excellent! (665 reviews)

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO

￥14,240

￥16,208 total

Aug 23 - Aug 24

includes taxes & fees

9.6/10 Exceptional! (165 reviews)

Holiday Inn Express & Suites Perryville by IHG

2020 Jefferson St Perryville MO

￥15,454

￥17,691 total

Sep 6 - Sep 7

includes taxes & fees

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

120 MUDDY MONSTER ROAD Murphysboro IL

￥18,162

￥20,157 total

Aug 23 - Aug 24

includes taxes & fees

9.4/10 Exceptional! (589 reviews)

Frequently asked questions

What's the best place for a stay in Perryville?

Holiday Inn Express & Suites Perryville by IHG is one of the top choices for your stay based on our traveler data. This hotel offers free breakfast and an indoor pool. Other good choices for your trip include Super 8 by Wyndham Perryville and Days Inn by Wyndham Perryville. See all available top hotels, or vacation rentals in Perryville.

What are some of the best vacation rentals in Perryville?

Silo Farm Haus- located in the heart of wine country!: This vacation home rental near Perryville is in a rural location and offers a Smart TV to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Perryville.

If I need to cancel my hotel reservation in Perryville, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Perryville.

Where can I learn more about changing or cancelling my trip to Perryville?

For additional details about picking new dates or cancelling your trip to Perryville, go to https://www.expedia.com/service/.

What is the top LGBTQ-friendly accommodation in Perryville?

Holiday Inn Express & Suites Perryville by IHG is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. See all available hotels listed as LGBTQ-friendly in Perryville.

What's the best pet-friendly place to stay in Perryville?

Days Inn by Wyndham Perryville is a top hotel for people traveling with their pets, and offers a seasonal outdoor pool and laundry facilities for its human guests. Other good choices for you and your pet include Perryville RV Resort and Super 8 by Wyndham Perryville. See more pet-friendly hotel accommodations in Perryville.

What's the best hotel to stay close to National Shrine of Our Lady of the Miraculous Medal?

Holiday Inn Express & Suites Perryville, an IHG Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 1.4 mi (2.3 km) from National Shrine of Our Lady of the Miraculous Medal. Other good options within a few miles include Super 8 by Wyndham Perryville and Days Inn by Wyndham Perryville.

What about the best place to stay near Missouri's National Veterans Memorial?

One of the top choices for your stay is Holiday Inn Express & Suites Perryville, an IHG Hotel, located 3.5 mi (5.6 km) from Missouri's National Veterans Memorial, and this hotel offers free breakfast and an indoor pool. Super 8 by Wyndham Perryville and Urban Lofts are a couple of other good options within a few miles.

What are some hotels with pools in Perryville?

Quality Inn Perryville I-55 is a top hotel with a seasonal outdoor pool, free breakfast, and free WiFi. View all hotels with pools in Perryville.

What's the best hotel for staying near Cape Girardeau Municipal Airport (CGI)?

Candlewood Suites Cape Girardeau is one of the top choices for your stay and is a popular hotel, featuring an indoor pool and free WiFi. It's located 4.4 mi (7 km) from Cape Girardeau Municipal Airport.

What is staying in Perryville like?

Visitors can enjoy all that Perryville has to offer including the wineries, golf courses, and coffeehouses. Tourists can also enjoy the city's festivals, university setting, and parks. In Perryville, there are 26 hotels and other accommodations to choose from. Find out more about Perryville.

What is there to see in Perryville?

Landmarks like National Shrine of Our Lady of the Miraculous Medal and Missouri's National Veterans Memorial might be worth a visit. Natural beauty is on display at Mark Twain National Forest, Mississippi River, and Saint Marys Lake. A couple of additional sights to add to your agenda are Feltz Street Park and Perryville City Hall. Check out what more to see and do in Expedia's Perryville guide.

What's the seasonal weather like in Perryville?

The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 39°F. Average annual precipitation for Perryville is 48 inches.

Find hotels in Perryville, MO from ￥12,111

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Perryville

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Perryville hotels

1. Holiday Inn Express & Suites Perryville by IHG

2. Perryville RV Resort

3. Super 8 by Wyndham Perryville

4. The Atrium - A Boutique Hotel

5. Days Inn by Wyndham Perryville

6. Quality Inn Perryville I-55

7. The Mediterranean House 1858

8. Urban Lofts

9. Drury Inn & Suites Jackson MO

10. Baymont by Wyndham Chester IL

11. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

12. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

13. Microtel Inn & Suites by Wyndham Sainte Genevieve

14. Triangle Inn Motel

15. Comfort Suites Jackson-Cape Girardeau

16. Tru By Hilton Cape Girardeau

17. Madison Inn Lodge

18. Sparta Motel Near St. Louis / Mississippi River IL

19. The Conner House B&B

20. Briarwood Inn of Sparta

Stay near popular Perryville attractions

National Shrine of Our Lady of the Miraculous Medal

Saint Marys Lake

Perryville Country Club

Missouri's National Veterans Memorial

County Lake State Wildlife Management Area

James M. Eddleman Millitary Museum

Feltz Street Park

Perryville City Hall

Perryville and related destinations

Top Perryville Hotel Reviews

Baymont by Wyndham Chester IL

Drury Inn & Suites Jackson MO

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Tru By Hilton Cape Girardeau

Microtel Inn & Suites by Wyndham Sainte Genevieve

Perryville RV Resort

Super 8 by Wyndham Perryville

New! Luxury Meets Nature - TreeRise at BaseCamp

Silo Farm Haus- located in the heart of wine country!

More cheap stays in Perryville

Super 8 by Wyndham Perryville

Baymont by Wyndham Chester IL

Microtel Inn & Suites by Wyndham Sainte Genevieve

Tru By Hilton Cape Girardeau

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app