Panacea, FL Vacation Homes from ￥37,308

A coastal resort with beachfront villas and a clear blue sky.

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Our top choices for Panacea vacation homes

A modern kitchen with a wooden countertop, a built-in sink, and a dining area with a table and chairs.

1. Panacea Treehouse⭐️ Quiet Waterfront - Boat Friendly Old Florida Experience

Panacea

Benjamin S.

￥51,441 total

includes taxes & fees

Sep 28 - Sep 29

A spacious living area with a high ceiling, a ceiling fan, a TV, and a view of the beach through the windows.

2. Cozy bayfront farmhouse!

Panacea

Scottie H.

A covered outdoor area with a wooden deck, white furniture, and a view of the water.

3. Tiny Tides Waterfront Cottage

Panacea

Jason W.

￥64,025 total

includes taxes & fees

Sep 27 - Sep 28

A dock extending into a body of water with a covered structure at the end.

4. Waterfront home on Ochlockonee Bay, private beach, fishing, dock and kayaks

Panacea

Toby H.

￥76,077 total

includes taxes & fees

Oct 1 - Oct 2

A wooden deck with wicker furniture, a small round table, and a view of the ocean.

5. Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock

Panacea

robin k.

A porch with wicker chairs and a small table, overlooking a lake and trees.

6. Point & Paddle Waterfront Retreat @Alligator Point

Alligator Point

Scott A.

￥77,069 total

includes taxes & fees

Sep 29 - Sep 30

A wooden deck with outdoor furniture, overlooking a beach and ocean.

7. BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.

Panacea

"We were traveling with 1 small dog, a 1 year old and 8 adults for 1 daughter graduation from FSU. The host confirmed the people coming and when we got there she had a cute little doggie set up ready and a high chair for our granddaughter. The property was perfect, the view was extraordinary. We are thrilled and will be back! It was an easy 1 hour drive from FSU to the house and we were so happy with everything about it!"

Stacy C.

￥98,682 total

includes taxes & fees

Oct 20 - Oct 21

A wooden deck with wicker chairs and a long table, overlooking a beach and ocean.

8. The Best Beach-Front House “Get-A-Way” in Florida

Panacea

Juliet H.

￥106,120 total

includes taxes & fees

Sep 25 - Sep 26

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Top Panacea Hotel Reviews

Hideaway Beach Cottage on waterfront with amazing views.

10/10 Excellent

"Booking this stay was incredibly easy. Hosts are responsive and very accommodating. Price was great, especially considering that we thought the property was even better in person. Pictures truly don’t do it justice. The small town of Panacea is a breath of fresh air. Not your typical touristy beach town. We wanted to have a slow, low stim vacation with our young kids and that’s exactly what we got. There are still enough restaurants to choose from if you want to eat out every night in the town and even more within a 20 minute drive. If you want to stay in and cook, the kitchen has plenty of room and is stocked well. Large dining table with more than enough room. The living area large and comfy. We didn’t use the second bedroom beds because our kids are still in pack and plays. Two fit in the room just fine. The master bedroom mattress was genuinely one of the most comfortable beds I’ve slept in. Screened in porch was amazing to relax in and let in 0 bugs somehow. So impressed. Our absolute favorite part though was the yard and little beach on the bay. Our kids can’t stand to be inside and they played for HOURS in the good sized yard. We watched stingrays, fish, and birds in the bay. The only thing I’d tell people to consider is that the beach can be a drive. The closest beach, Mashes Sands, had almost no shoreline so you’ll need to drive \- 20 minutes for a beach. This didn’t bother us at all. There is virtually no traffic and tons of options."

Great sunrise view from dining area and decks. Easy beach access.

8/10 Good

"When we arrived there was construction happening in front of the property (building a house directly in front of this one). Unfortunately it was blocking the unobstructed ocean view that was advertised. The construction was going to take place during the entire time of our stay. I contacted the host Kevin to let him know of the construction and that we would prefer to move to a different property since it was not as advertised and the noise would be an issue. . He was very understanding and we worked out to stay a couple days until after the holiday weekend so to be able to move to another property. He offered a refund for the days we would be leaving and even allowed for a late checkout to check into the new property. He was an awesome host and very accommodating for the unfortunate timing of the construction . Unfortunately VRBO didn't offer a refund on the taxes and fees (they only offered a small vrbo credit) so I ended up paying an extra few hundred dollars to move locations. Overall given that neither us, nor the host, knew about the construction we worked it out the best we could. Kevin was one of the best hosts to deal with. Wish the house construction wasn't taking place and we could have stayed the entire week."

Coastal Getaway on canal-steps to the beach

10/10 Excellent

"Awesome weekend staying at this location. We was within walking distance to the beach and fishing. Loved that it had a complete bathroom downstairs when we came in from fishing all day and night. Great communication with the host. Very prompt responding to questions. Will recommend to family and friends!!"

Find out more about Panacea

Panacea Vacation Homes information

Number of reviews	585
Accommodation	240 Vacation Homes
Lowest Price	￥37,308
Highest Price	￥320,175

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Our top choices for Panacea vacation homes

1. Panacea Treehouse⭐️ Quiet Waterfront - Boat Friendly Old Florida Experience

2. Cozy bayfront farmhouse!

3. Tiny Tides Waterfront Cottage

4. Waterfront home on Ochlockonee Bay, private beach, fishing, dock and kayaks

5. Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock

6. Point & Paddle Waterfront Retreat @Alligator Point

7. BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.

8. The Best Beach-Front House “Get-A-Way” in Florida

9. NEW - St. Teresa Beach Escape w/ Private Beach Acc

10. 7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

11. Dragonfly on the Canal Golf cart included!

12. Waterfront -Beautiful sunsets, great fishing, scalloping & bird watching

13. Canal-front home at Shell Point. Relax. Fish. Explore. Swim. Amazing Sunsets!

14. The Oyster Bed- Riverwalk Cottages Unit 204 B

15. The Sand Dollar - Riverwalk Cottages Unit 204 A

16. Beach/Marina/Walking trails and more…

17. 4-bedroom estate in close to FSU FAMU and Florida State Capital

18. FISHERMAN'S PARADISE!! Cozy home 2 minutes to the Gulf

19. The Blue Crab at Riverwalk Cottages Unit 202B

Find vacation rentals that suit your style

Top Panacea Hotel Reviews

Hideaway Beach Cottage on waterfront with amazing views.

Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes +

Great sunrise view from dining area and decks. Easy beach access.

Lighthouse- enjoy the water, bask in the view

The Panacea Motel

Coastal Getaway on canal-steps to the beach

Beautiful Waterfront, Pool, Private Hot Tub, Golf Cart, Kayaks, Bikes & Tennis

Best deal at Alligator Point

Waterfront Home: Spectacular On-Site Fishing!

Find out more about Panacea

Panacea Vacation Homes information

Explore a world of travel with Expedia

Search Vacation Homes in Panacea

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Panacea vacation homes

1. Panacea Treehouse⭐️ Quiet Waterfront - Boat Friendly Old Florida Experience

2. Cozy bayfront farmhouse!

3. Tiny Tides Waterfront Cottage

4. Waterfront home on Ochlockonee Bay, private beach, fishing, dock and kayaks

5. Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock

6. Point & Paddle Waterfront Retreat @Alligator Point

7. BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.

8. The Best Beach-Front House “Get-A-Way” in Florida

9. NEW - St. Teresa Beach Escape w/ Private Beach Acc

10. 7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

11. Dragonfly on the Canal Golf cart included!

12. Waterfront -Beautiful sunsets, great fishing, scalloping & bird watching

13. Canal-front home at Shell Point. Relax. Fish. Explore. Swim. Amazing Sunsets!

14. The Oyster Bed- Riverwalk Cottages Unit 204 B

15. The Sand Dollar - Riverwalk Cottages Unit 204 A

16. Beach/Marina/Walking trails and more…

17. 4-bedroom estate in close to FSU FAMU and Florida State Capital

18. FISHERMAN'S PARADISE!! Cozy home 2 minutes to the Gulf

19. The Blue Crab at Riverwalk Cottages Unit 202B

Find vacation rentals that suit your style

Top Panacea Hotel Reviews

Hideaway Beach Cottage on waterfront with amazing views.

Find out more about Panacea

Panacea Vacation Homes information

Explore a world of travel with Expedia