The Best Hotels Closest to Orlando Regional Medical Center in Orlando for 2026

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Our top choices for Orlando Regional Medical Center hotels

A stone wall, a brown sofa with orange and yellow cushions, a glass table with a fire feature, and a wooden door with decorative glass panels.

A round mirror reflecting a couple on a bed with a wooden headboard, a lamp, and a small shelf.

A bar area with a long counter, bar stools, and a variety of bottles and glasses.

A reception desk with a dark wooden panel and illuminated letters spelling "BELAN HOTEL".

1. The Delaney Hotel

South Orange, 0.1 km from Orlando Regional Medical Center

Alexandra

￥19,070

￥21,454 total

includes taxes & fees

Sep 7 - Sep 8

A breakfast bar with various food items and a clock on the wall.

A modern living room with a sofa, armchairs, a coffee table, and lamps.

A reception desk with a welcome sign for The Sun Shingle State, a stone wall, and a view of the lobby area.

A hotel lobby with a 'Treats' section featuring snacks and beverages, a chalkboard with 'Treats' written on it, and a 'Welcome to Orlando' sign.

2. Hampton Inn & Suites Orlando/Downtown South - Medical Center

South Orange, 0.4 km from Orlando Regional Medical Center

wesly

￥16,162

￥18,182 total

includes taxes & fees

Sep 6 - Sep 7

A hotel with a modern facade, multiple floors, and a rooftop pool area.

A modern lounge area with a central fire feature, comfortable seating, and a large flat-screen TV.

A bar area with a long counter, multiple shelves of bottles, and several chairs.

An outdoor patio with wooden flooring, yellow chairs, a round table, and a seating area with sofas and a red umbrella.

3. Aloft by Marriott Orlando Downtown

City District, 1.3 km from Orlando Regional Medical Center

Laron

￥20,218

￥22,746 total

includes taxes & fees

Aug 31 - Sep 1

A rooftop lounge with outdoor seating, a fire feature, and a view of the cityscape.

A modern glass building with a prominent vertical glass facade and a corner entrance.

A modern bar area with a long counter, multiple seating options, and large windows offering a city view.

A rooftop bar with a long counter, multiple bar stools, and a city view.

4. AC Hotel by Marriott Orlando Downtown

City District, 1.6 km from Orlando Regional Medical Center

Brandie

￥21,752

￥24,471 total

includes taxes & fees

Aug 31 - Sep 1

A modern living room with a sofa, armchairs, a coffee table, and a piano.

A modern hotel lobby with a large mirror, a chandelier, and a seating area.

A modern living room with a large TV, comfortable seating, a chandelier, and a view of the outdoors.

A modern outdoor seating area with two white lounge chairs and a large umbrella, surrounded by potted plants and a glass door leading to an interior space.

5. TownePlace Suites by Marriott Orlando Downtown

South Orange, 0.4 km from Orlando Regional Medical Center

Robert

￥19,869

￥22,352 total

includes taxes & fees

Sep 10 - Sep 11

A modern bar area with high ceilings, multiple levels, and a variety of seating options including bar stools and tables.

A hotel room with a sofa, armchairs, a dining table, and a kitchen area.

A modern hotel lobby with a reception desk, a seating area with a sofa, a bookshelf, and a large chandelier.

A hotel room with a bathroom, a bed, and a balcony with curtains.

6. Embassy Suites by Hilton Orlando Downtown

Downtown Orlando, 1.8 km from Orlando Regional Medical Center

Kendall

￥24,634

￥27,713 total

includes taxes & fees

Aug 27 - Aug 28

A modern indoor dining area with green chairs and tables, large windows with a city view, and string lights on the ceiling.

A modern hotel lobby with a central refreshment station stocked with snacks, beverages, and a minibar.

A rooftop pool with lounge chairs and tables, surrounded by city buildings.

A covered outdoor seating area with multiple tables and chairs, a brick building in the background, and a palm tree.

7. Home2 Suites by Hilton Orlando Downtown

2.5 km from Orlando Regional Medical Center

Helene

￥19,421

￥21,848 total

includes taxes & fees

Aug 31 - Sep 1

A spacious living area with a large sofa, dining table, and chairs, a fireplace, and large windows offering a view of greenery.

A modern outdoor living area with a fireplace, comfortable seating, and large windows offering views of greenery.

A multi-story hotel with a modern design, featuring a mix of residential and commercial spaces, situated in an urban area with a view of the city skyline.

A modern kitchen with a built-in grill, a fireplace, and a dining area with outdoor seating.

8. Residence Inn by Marriott Orlando Downtown

Downtown Orlando, 3.1 km from Orlando Regional Medical Center

Aubrey

￥18,756

￥21,101 total

includes taxes & fees

Aug 30 - Aug 31

A modern coffee shop with a counter, seating area, and display cases.

A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.

9. Hilton Garden Inn Orlando Downtown

2.5 km from Orlando Regional Medical Center

Lisa

￥18,117

￥20,381 total

includes taxes & fees

Aug 31 - Sep 1

A bar area with a long counter, multiple stools, and a chandelier.

A luxurious lobby with a checkered floor, a chandelier, and black and gold decor.

A modern interior with a black and white patterned floor, a bar area, and a seating area with sofas and chairs.

A modern outdoor seating area with wicker furniture, a white sofa, and round tables.

10. Grand Bohemian Orlando, Autograph Collection

City District, 1.5 km from Orlando Regional Medical Center

RANDALL BRIAN

￥29,565

￥33,260 total

includes taxes & fees

Sep 6 - Sep 7

A high-rise hotel with multiple floors, a parking area, and a road with traffic lights.

A spacious living room with a sectional sofa, patterned armchairs, a coffee table, and a dining area with yellow chairs.

A modern living room with a large flat-screen TV, a grey sofa, a blue patterned rug, and a white floor lamp.

11. Crowne Plaza Orlando - Downtown by IHG

3.1 km from Orlando Regional Medical Center

Monica

￥18,756

￥21,101 total

includes taxes & fees

Aug 30 - Aug 31

A spacious lobby with a large flat-screen TV, seating areas, and a modern design.

A modern restaurant with multiple dining areas, a bar, and a TV screen.

A rooftop pool area with lounge chairs, umbrellas, and a city skyline in the background.

12. Marriott Orlando Downtown

2.6 km from Orlando Regional Medical Center

Sara

￥23,684

￥26,643 total

includes taxes & fees

Aug 30 - Aug 31

13. Suites by The Wellborn

1.2 km from Orlando Regional Medical Center

Edward

￥16,477

￥18,536 total

includes taxes & fees

Aug 25 - Aug 26

A covered patio with a table and chairs, surrounded by a white railing and a view of greenery.

A reception area with a dark wooden desk, a potted orchid, and a laptop. A staircase leads to another floor.

A modern lobby with a reception desk, seating area, and a large window.

A white building with a sign for 'Hotel Specials!' and a contact number.

14. The Eo Inn - Downtown

2.4 km from Orlando Regional Medical Center

Manuel

￥13,439

￥15,119 total

includes taxes & fees

Aug 26 - Aug 27

A bedroom with a bed, a desk with a chair, a TV, and a window with a view of the ocean.

A parking lot with a row of single-story motel buildings, each with a blue door and a balcony.

A bathroom with a bathtub, toilet, and sink.

A parking lot with multiple cars and a building with a row of rooms.

15. Budget Motel

2 km from Orlando Regional Medical Center

Alyssa

￥15,256

￥17,162 total

includes taxes & fees

Aug 30 - Aug 31

A modern kitchen with a central island, bar stools, and a dining area with a sofa and table.

A modern hotel lobby with a glass staircase, a reception desk, and a view of the outdoors.

An outdoor seating area with a sofa, chairs, and a table.

A modern kitchen with a central island, bar stools, and a seating area with a sofa and table.

16. Virelli Apartments Upscale King Suite in the Heart of Orlando w Pool

Downtown Orlando, 2.7 km from Orlando Regional Medical Center

John

￥16,213

￥62,467 total

includes taxes & fees

Aug 30 - Aug 31

A hotel room with a large bed, two bedside lamps, a desk with a chair, a television, and a window with curtains.

A hotel lobby with a reception desk, seating area, and large windows offering a view outside.

A gas station with a fountain, a Pepsi sign, and a paved area with a brick pattern.

A dining area with tables and chairs, a television mounted on the wall, and a view of the outside through large windows.

17. Days Inn by Wyndham Orlando Downtown

2.8 km from Orlando Regional Medical Center

Jacqueline

￥9,951

￥11,869 total

includes taxes & fees

Aug 25 - Aug 26

A multi-story hotel with a modern design, featuring balconies and a covered entrance.

An outdoor patio area with wicker furniture, a glass table, and a view of a building in the background.

A modern bar area with a curved counter, bar stools, and a variety of liquor bottles.

A modern living room with a large flat-screen TV, blue sofas, a round coffee table, and a bookshelf.

18. Courtyard by Marriott Orlando Downtown

3.2 km from Orlando Regional Medical Center

Talan

￥19,455

￥21,888 total

includes taxes & fees

Aug 27 - Aug 28

A hotel with multiple floors, outdoor seating areas, and a well-lit courtyard.

A spacious lobby with a high ceiling, large windows, and a grand piano.

A spacious hall with a grand piano, large windows, and a central floral arrangement.

An outdoor dining area with tables and chairs, string lights, and a building with arches and balconies.

19. The Alfond Inn

8.4 km from Orlando Regional Medical Center

Elliott

￥38,482

￥48,121 total

includes taxes & fees

Aug 27 - Aug 28

An outdoor seating area with green chairs and umbrellas, a fire pit, and a building with large windows in the background.

A multi-story hotel with a prominent red sign, a well-lit entrance, and a landscaped front yard.

A hotel room with a sofa, two armchairs, a coffee table, and a wall-mounted sign reading "gateway village - ORLANDO stay a while".

A bar area with a long counter, multiple seating options, and a television screen.

20. Hampton Inn & Suites Orlando Airport @ Gateway Village

Airport North, 9.8 km from Orlando Regional Medical Center

andrea

￥14,207

￥15,983 total

includes taxes & fees

Aug 31 - Sep 1

View all properties

Compare popular hotels close to Orlando Regional Medical Center

Property	Star rating	Guest rating
The Delaney Hotel	9.6 Exceptional 1,202 reviews	View
Hampton Inn & Suites Orlando/Downtown South - Medical Center	9.4 Exceptional 1,009 reviews	View
Aloft by Marriott Orlando Downtown	9.4 Exceptional 1,134 reviews	View
AC Hotel by Marriott Orlando Downtown	9.4 Exceptional 1,323 reviews	View
TownePlace Suites by Marriott Orlando Downtown	9.4 Exceptional 510 reviews	View

Top Orlando Regional Medical Center Hotel Reviews

TownePlace Suites by Marriott Orlando Downtown

10/10 Excellent

"Everything"

The Delaney Hotel

10/10 Excellent

"Me and My Fiancée love this hotel!! It's always our go-to when coming to Orlando and plan to be back soon 100%"

Grand Bohemian Orlando, Autograph Collection

10/10 Excellent

"My husband and I recently stayed at the Grand Bohemian Orlando Autograph Collection and we were absolutely blown away by our experience. From the moment we arrived, we were impressed by the hotel’s stunning décor and elegant atmosphere. The photos online simply do not do this property justice. It is far more beautiful, warm, and inviting in person than we ever expected. The level of customer service truly enhanced our experience. Our room was spacious, spotless, and exceptionally comfortable. We had breakfast at the hotel’s restaurant, was absolutely delicious. Another major plus is the location. The hotel is within walking distance of numerous restaurants and a Corona Cigar Lounge, making it easy to enjoy downtown Orlando without constantly needing to drive. While parking was approximately $42–$45 per night, we found it to be well worth the cost considering the convenience, service, and overall quality of the stay. This hotel exceeded our expectations in every way and made our weekend getaway truly special."

Hilton Garden Inn Orlando Downtown

10/10 Excellent

"First time staying at this particular Hotel in downtown orlando, i honestly liked it. traveled by myself for a small little event - if you're a coffee lover there's a starbucks literally 5 steps out the main entrance of the hotel. There's also some restauraunts around the lake nearby to walk around. Super friendly staff, i didn't have the chance to eat their breakfast but for dinner stayed at the bar ordered some wings and french fries which was really good. Overall its quiet hotel, enjoyed it."

Embassy Suites by Hilton Orlando Downtown

10/10 Excellent

"It was awesome. I’d definitely stay again. Maybe when I come back for EDC Orlando even"

At Lakes Upscale Villa/Next to Downtown Orlando

10/10 Excellent

"We were happy surprise with our stay. The house was clean, loaded with all items required to facilitate our staying. pictures don’t express how pleasant and comfortable the place is. The host was also very responsive and friendly. Next time I return to Orlando, I will try to stay there again."

New! Modern Home - 4 Beds 2.5 Baths - 5 minutes from Downtown

10/10 Excellent

"Everything was as advertised. AC worked great, good water pressure in the shower. Beds were comfortable."

Large, beautiful, very comfortable one bedroom on small lake

10/10 Excellent

"Great place. Totally non Orlando. Great district. Place is like an apartment hotel. Great gymn, spa, even a sauna. And entertainment options. Will.come again!"

LUXURY 6000 sqft Mansion Downtown Orlando 6BR/5BA SLEEPS 14 Arcade Rooftop Deck

8/10 Good

"Check in was efficient and easy. Location couldn’t be better!"

Frequently asked questions

What's the area like around Orlando Regional Medical Center?

Orlando Regional Medical Center is located in a welcoming area of Orlando known for its beautiful lakeside setting and golfing. If you're looking for a convenient place to stay, check out the 44 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Orlando Regional Medical Center?

Adjacent to Orlando Regional Medical Center, The Delaney Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and a 24-hour fitness center. Other good options within a short distance include TownePlace Suites by Marriott Orlando Downtown and Hampton Inn & Suites Orlando/Downtown South - Medical Center.

How many hotels will I find near Orlando Regional Medical Center?

Expedia has 44 hotels and other accommodations within a mile from Orlando Regional Medical Center.

If I need to cancel the hotel reservation for my stay near Orlando Regional Medical Center, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within 24 hours of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the best options available near Orlando Regional Medical Center.

Where can I learn more about changing or cancelling my trip in the area near Orlando Regional Medical Center?

For additional details about changing or cancelling your stay near Orlando Regional Medical Center, head over to our customer service page.

What can I see and do near Orlando Regional Medical Center?

You might want to spend some time browsing the exhibits at Orlando Science Center, Orlando Museum of Art, or Orange County Regional History Center. Explore landmarks like Church Street Station, Wells' Built Museum, and Urban League of Orlando. You can watch performances at Dr. Phillips Center for the Performing Arts, The Social, and The Plaza Theatre if you're interested in local theater.

How can I get to Orlando Regional Medical Center?

If you're hopping a train into the city, Orlando Station is the closest stop to South Orange. There might not be many public transit options to choose from near Orlando Regional Medical Center so consider a car rental to maximize your time.

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Treat yourself

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Our top choices for Orlando Regional Medical Center hotels

1. The Delaney Hotel

2. Hampton Inn & Suites Orlando/Downtown South - Medical Center

3. Aloft by Marriott Orlando Downtown

4. AC Hotel by Marriott Orlando Downtown

5. TownePlace Suites by Marriott Orlando Downtown

6. Embassy Suites by Hilton Orlando Downtown

7. Home2 Suites by Hilton Orlando Downtown

8. Residence Inn by Marriott Orlando Downtown

9. Hilton Garden Inn Orlando Downtown

10. Grand Bohemian Orlando, Autograph Collection

11. Crowne Plaza Orlando - Downtown by IHG

12. Marriott Orlando Downtown

13. Suites by The Wellborn

14. The Eo Inn - Downtown

15. Budget Motel

16. Virelli Apartments Upscale King Suite in the Heart of Orlando w Pool

17. Days Inn by Wyndham Orlando Downtown

18. Courtyard by Marriott Orlando Downtown

19. The Alfond Inn

20. Hampton Inn & Suites Orlando Airport @ Gateway Village

Compare popular hotels close to Orlando Regional Medical Center

Top Orlando Regional Medical Center Hotel Reviews

TownePlace Suites by Marriott Orlando Downtown

The Delaney Hotel

Grand Bohemian Orlando, Autograph Collection

Hilton Garden Inn Orlando Downtown

Embassy Suites by Hilton Orlando Downtown

At Lakes Upscale Villa/Next to Downtown Orlando

New! Modern Home - 4 Beds 2.5 Baths - 5 minutes from Downtown

Large, beautiful, very comfortable one bedroom on small lake

LUXURY 6000 sqft Mansion Downtown Orlando 6BR/5BA SLEEPS 14 Arcade Rooftop Deck

Frequently asked questions

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