Northeast Missouri, MO
Travel Guide
Visit Northeast Missouri
Where to stay in Northeast Missouri
Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and Enterprise Center are top sights worth seeing.
Berkeley
Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
Soulard
You'll enjoy the bars and churches in Soulard. You might want to make time for a stop at Anheuser-Busch Brewery or Soulard Farmer's Market.
Pear Tree Inn St. Louis Near Union Station
We stayed here in town for cardinals games. The hotel was very clean. The staff were all friendly and very helpful. The pool area is nice and we enjoyed the breakfast. I would go back
Reviewed on Mar 29, 2026
21C Museum Hotel St Louis
Arrived to an overcrowded lobby, with no luggage carts, and one broken elevator. Asked the front desk to send up wine glasses, they agreed and never did. Shower was full of scum, tiles were stained, one of the soap dispensers was ripped off the wall, and the shower leaked on the floor. We ordered ...
Reviewed on Mar 28, 2026
Clayton Plaza Hotel & Extended Stay
Unfortunately this hotel experience was a disappointment. We were given a room that was locked from inside, and when I complained this has never happened to us, the staff remarked, "It happens to us all the time!" - which did not say a lot about the property upkeeping or management. The room smelled ...
Reviewed on Mar 29, 2026
White House at Grand Central
Stunning Townhome 920 in The Grove
We arrived at the townhouse and the bed sheets on every bed were stained and had hair on them. The floors had garbage on the floor. The bathroom curtains had mold and the toilets were dirty. We didn’t take towels since it was listed on there but the ones they had were dirty we had to go buy some. ...
Reviewed on Mar 9, 2026
Settle into Soulard! 6 beds 2 full baths!
Clean, convenient and satisfied our needs for this stay.
Reviewed on Mar 11, 2026
Popular places to visit
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theater scene or attend a baseball game.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Forest Park
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
Dome at America’s Center
Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's acclaimed art scene and fascinating museums.
Things to do
Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour
Tom's Town Distillery Tour and Tasting
Kansas City: Country Club Plaza Escape Game
Astounding Scavenger Hunt: Fountains, Fun & Hidden Finds
Explore a world of travel with Expedia
- Brookfield Hotels
- Boutique Hotels in Hannibal
- B&B in New London
- Luxury Hotels in Cairo
- B&B in Kahoka
- Hotels with a Pool in New London
- Cabin Rentals in Mexico
- B&B in Hannibal
- Hotels near Mark Twain State Park
- Mexico Hotels
- Cheap Hotels in Cairo
- Gay friendly Hotels in Mexico
- B&B in Northeast Missouri
- Clark Hotels
- Cheap Hotels in New London
- Lodges in Taylor
- Cairo Hotels
- Pet-Friendly Hotels in Memphis
- Shelbina Hotels
- Aparthotels in Mexico
- Cheap Hotels in Monroe City
- B&B in Centralia
- Apartments in Cairo
- Cheap Hotels in Clark
- Hannibal Hotels
- Hotels near Finger Lakes State Park
- Luxury Hotels in Hannibal
- Boutique Hotels in Mexico
- Cheap Hotels in Canton
- Huntsville Hotels
- Hotels near Mark Twain Cave
- Hotels with a Pool in Cairo
- Cheap Hotels in Moberly
- Cheap Hotels in Paris
- Kirksville Hotels
- Paris Hotels
- B&B in Paris
- Resorts & Hotels with Spas in Kahoka
- Inns in Kahoka
- Motels in Center
- Palmyra Hotels
- Memphis Hotels
- St. Louis Union Station
- Busch Stadium
- St. Louis Zoo
- Washington University in St. Louis
- Six Flags St. Louis
- City Museum
- Barnes Jewish Hospital
- Hollywood Casino Amphitheatre
- Fox Theater
- Grant's Farm
- Route 66 State Park
- Magic House - St. Louis Children's Museum
- Anheuser-Busch Brewery
- St. Louis Aquarium at Union Station
- Missouri Botanical Gardens and Arboretum
- St. Louis Science Center