Northeast Missouri, MO
Travel Guide
Visit Northeast Missouri
Where to stay in Northeast Missouri
Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
Berkeley
Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.
St. Charles Historic District
Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Great stay. Superb staff. Rooms were beautiful except bathroom very dated and the corners were not very clean
Reviewed on Dec 25, 2025
Clayton Plaza Hotel & Extended Stay
Yes. The staff was nice and very helpful.
Reviewed on Dec 25, 2025
21C Museum Hotel St Louis
The entire hotel was fantastic. Beautifully decorated, so much to see. The art gallery was fantastic, the servers at the bar were friendly and phenomenal and just made for a great evening. The food was fantastic. Every inch of the building was well styled and the room was fantastic. Can’t wait to ...
Reviewed on Dec 22, 2025
White House at Grand Central
The property was wonderful, perfect, beautiful. We loved it
Reviewed on Nov 25, 2025
Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!
The host was very friendly. The property is in a great area of the neighborhood, clean, and equipped with everything you need.
Reviewed on Dec 7, 2025
Luxury 2BEDROOM LOFT near Bush Stadium
Excellent
Reviewed on Dec 15, 2025
Popular places to visit
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
City Museum
This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.
Forest Park
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
Fox Theater
You can get tickets for a performance at Fox Theater during your stay in St. Louis. Experience the area's great live music and acclaimed art scene.
Things to do
Tom's Town Distillery Tour and Tasting
Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour
Kansas City: Country Club Plaza Escape Game
Kansas City Scavenger Hunt: Fountains, Fun & Hidden Finds
Explore a world of travel with Expedia
- Brookfield Hotels
- Boutique Hotels in Hannibal
- B&B in New London
- Luxury Hotels in Cairo
- B&B in Kahoka
- Hotels with a Pool in New London
- Cabin Rentals in Mexico
- B&B in Hannibal
- Hotels near Mark Twain State Park
- Mexico Hotels
- Cheap Hotels in Cairo
- Gay friendly Hotels in Mexico
- B&B in Northeast Missouri
- Clark Hotels
- Cheap Hotels in New London
- Lodges in Taylor
- Cairo Hotels
- Pet-Friendly Hotels in Memphis
- Shelbina Hotels
- Aparthotels in Mexico
- Cheap Hotels in Monroe City
- B&B in Centralia
- Apartments in Cairo
- Cheap Hotels in Clark
- Hannibal Hotels
- Hotels near Finger Lakes State Park
- Luxury Hotels in Hannibal
- Boutique Hotels in Mexico
- Cheap Hotels in Canton
- Huntsville Hotels
- Hotels near Mark Twain Cave
- Hotels with a Pool in Cairo
- Cheap Hotels in Moberly
- Cheap Hotels in Paris
- Kirksville Hotels
- Paris Hotels
- B&B in Paris
- Resorts & Hotels with Spas in Kahoka
- Inns in Kahoka
- Motels in Center
- Palmyra Hotels
- Memphis Hotels
- St. Louis Union Station
- Busch Stadium
- Washington University in St. Louis
- Barnes Jewish Hospital
- St. Louis Zoo
- City Museum
- Six Flags St. Louis
- Fox Theater
- Hollywood Casino Amphitheatre
- Anheuser-Busch Brewery
- Route 66 State Park
- Missouri Botanical Gardens and Arboretum
- Magic House - St. Louis Children's Museum
- St. Louis Aquarium at Union Station
- St. Louis Premium Outlets
- Grant's Farm
- St. Louis Science Center