Northeast Missouri Vacations

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Where to stay in Northeast Missouri

Find the best Northeast Missouri areas and neighborhoods for the activities you enjoy most. Learn more about Northeast Missouri
The illuminated Gateway Arch at night with a city skyline in the background.

Clayton

1 out of top 10 points of interest in this area

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

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A street with parked cars, a building with a sign reading "Brennan's", and a tree in front.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

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A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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An ornate hall with arched ceilings and intricate patterns.

Downtown West

3 out of top 10 points of interest in this area

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

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A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

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Find the Best Northeast Missouri Vacation Packages

Northeast Missouri Hotel Deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
￥14,944
￥17,445 total
Aug 30 - Aug 31
includes taxes & fees
9/10 Wonderful! (3,353 reviews)
"Front desk rude. Room smelled funny. Bed had a stain. In a nice part of town but don’t let the outside food you it’s worse inside. I would have rather stayed at red room inn"

Reviewed on Aug 29, 2026

Clayton Plaza Hotel & Extended Stay
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
￥15,920
￥23,308 total
Sep 15 - Sep 16
includes taxes & fees
Hollywood Casino & Hotel St. Louis
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
￥14,952
￥17,633 total
Sep 3 - Sep 4
includes taxes & fees
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
See all 3,012 properties in Northeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Northeast Missouri attractions

A baseball stadium with a large crowd, a prominent arch structure, and various advertisements.
Photo by Carl Guttovz

Busch Stadium

9.4/10 (4,850 reviews)
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
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A bronze elephant sculpture with a pumpkin on its back, surrounded by greenery.
Photo by Jeff White

St. Louis Zoo

9.2/10 (4,367 reviews)
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
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A cityscape with a prominent statue in the center, surrounded by various buildings and a large stadium.

Enterprise Center

8.8/10 (1,597 reviews)
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
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A cityscape with a prominent arch structure, various high-rise buildings, and a large government building.

Dome at America’s Center

8.4/10 (1,229 reviews)
Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's great live music and fascinating museums.
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A modern building with large glass windows, surrounded by a garden with red and pink tulips and purple flowers.

Forest Park

9.2/10 (3,389 reviews)
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
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A historic building with a large lawn, a flagpole with flags, and a clear blue sky.

St. Louis University

8.6/10 (526 reviews)
Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.
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A tightrope walker balancing on a wire between buildings.

City Museum

9.0/10 (3,209 reviews)
This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.
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America's Center Convention Complex

8.8/10 (306 reviews)
Learn about the events happening at America's Center Convention Complex during your trip to St. Louis. Experience the area's fascinating museums and acclaimed art scene.
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What to do in Northeast Missouri

Kansas City, MO: Attractions Pass

Kansas City, MO: Attractions Pass

￥4,788
per adult
100% of travellers recommend
Kansas City, MO: Attractions Pass
Kansas City MO Attractions Pass

Kansas City MO Attractions Pass

￥4,788
per adult
Kansas City MO Attractions Pass
Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour

Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour

￥5,586
per adult
Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour
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Frequently asked questions

How much does a Northeast Missouri vacation package cost?
Live it up in Northeast Missouri from as little as . Choose from a great selection of flights, hotels and rental cars to suit your travel style. You can score even more discounts when you add a few sightseeing activities to your vacation package.
How do I get a cheap travel package to Northeast Missouri?
Our Northeast Missouri vacation packages promise plenty of savings for the savvy explorer. For the best deal, simply bundle your flights, hotels and extras (including tours) into a handy package. But low prices are only the start of your next memorable adventure. Book with Expedia and you'll have more than 550 airlines and 1,000,000 hotel options around the globe to choose from. No matter your budget or style, there's a vacation package that's perfect for you.
Where should I stay in Northeast Missouri?
You'll love St. Louis. Popular attractions, like Busch Stadium and Gateway Arch, will keep you entertained in this happening city.
What are the top hotels in Northeast Missouri?
For properties in St. Louis with comfy beds and friendly service, you can't top Hyatt Regency St. Louis at The Arch and Clayton Plaza Hotel & Extended Stay. If you're swinging by Wright City as well, you can look forward to a wonderful night's sleep at Holiday Inn Express Warrenton, an IHG Hotel or Super 7 Inn.
How far in advance should I book my Northeast Missouri vacation?
While not all airlines advertise ticket prices early, you can usually look up international flights on Expedia up to 12 months in advance. This is the time you'll bag some incredible deals. If you're booking late, you could still be in luck. Low prices sometimes become available a few weeks prior to departure.
What does an Expedia Northeast Missouri travel package include?
That depends on what you're looking for. If you're traveling solo, you might decide to combine hotels and flights. Bringing the whole crew to Northeast Missouri? A travel package including rental cars, flights and hotels might suit you better. Expedia gives you the flexibility to customize your travel package.
What should I know before booking a Northeast Missouri travel package?
Discover deals that fit your budget with an Expedia package. Airfares, hotels, rental cars — we're a one-stop shop for all of them. You'll save loads just for bundling your bookings. Whether you're embarking on a snow and ski adventure or kicking back on a warm beach, your dream getaway is only clicks away.
Can I choose my airline with a Northeast Missouri Expedia vacation package?
With a vacation package, the choice is in your hands. Whether you're hoping to fly to Northeast Missouri in business or coach, simply choose from the available airline options. Expedia has access to over 550 partner airlines globally.
If I'm not able to travel, can I cancel my Northeast Missouri vacation package?
If your vacation plans in Northeast Missouri have been upended, it's comforting to know that it's possible to amend or cancel your booking. If your booking was made within the last 24 hours, you may be able to get a refund. If your booking is older than that, your hotel, airline or car rental company may impose a fee. To find out more, check our Customer Service Portal.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.