Find hotels near Museum of Life and Science, Raleigh from ￥10,580

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Dec 28 - Dec 29
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Our top choices for Museum of Life and Science hotels

Lobby
Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85
2.5 star property
1.4 km from Museum of Life and Science
9.0 out of 10, Wonderful, (1004)
"Very clean hotel. Staff was very pleasant and helpful."
United States
Brenda
The price is ￥17,846
￥20,255 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Hampton Inn & Suites Durham/North I-85
Free buffet breakfast
Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG
2.5 star property
2.2 km from Museum of Life and Science
8.8 out of 10, Excellent, (958)
"We arrived at 12:25am. We were welcomed warmly and it was a very nice and pleasant check-in. The staff member that checked us in was so great. "
United States
Timothy
The price is ￥15,187
￥17,238 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Holiday Inn Express Durham by IHG
Premium bedding, desk, blackout drapes, iron/ironing board
Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University
2.5 star property
Croasdaile Farm Master, 3.2 km from Museum of Life and Science
8.6 out of 10, Excellent, (1003)
"Friendly staff, clean room, nice breakfast"
United States
Jessica
The price is ￥14,725
￥16,713 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Comfort Inn & Suites Durham near Duke University
Lobby
Red Roof Inn Durham - Duke Univ Medical Center

Red Roof Inn Durham - Duke Univ Medical Center

Red Roof Inn Durham - Duke Univ Medical Center
2.0 star property
2.2 km from Museum of Life and Science
6.8 out of 10, (1003)
"Good motel...clean, easy acess "
United States
Howard
The price is ￥9,087
￥10,580 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Red Roof Inn Durham - Duke Univ Medical Center
Apartment | 1 bedroom
Walk to Duke Campus 1 Bedroom in Trinity Park

Walk to Duke Campus 1 Bedroom in Trinity Park

Walk to Duke Campus 1 Bedroom in Trinity Park
2.0 star property
Trinity Park, 2.9 km from Museum of Life and Science
6.0 out of 10, (2)
"Fantastic neighborhood. Nice apartment - very neat and tidy. Easy to find, good communication with management company. Would stay here again. "
United States
Brittney
The price is ￥9,402
￥22,187 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Walk to Duke Campus 1 Bedroom in Trinity Park
Garden
Arrowhead Inn

Arrowhead Inn

Arrowhead Inn
4.5 star property
9.8 km from Museum of Life and Science
9.8 out of 10, Exceptional, (119)
"Bed was very comfortable, breakfast was yummy, and the surroundings were beautiful"
United States
Ronald
The price is ￥29,797
￥33,820 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Arrowhead Inn
Reception
Hampton Inn & Suites Durham University Medical Center

Hampton Inn & Suites Durham University Medical Center

Hampton Inn & Suites Durham University Medical Center
2.5 star property
4.8 km from Museum of Life and Science
9.6 out of 10, Exceptional, (403)
"Great breakfast, clean rooms and beds "
United States
Fabiola B
The price is ￥17,847
￥20,256 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Hampton Inn & Suites Durham University Medical Center
Indoor pool
Washington Duke Inn & Golf Club

Washington Duke Inn & Golf Club

Washington Duke Inn & Golf Club
4.0 star property
5.9 km from Museum of Life and Science
9.4 out of 10, Exceptional, (1009)
"Beautiful hotel. The staff is fabulous! Went out of their way to make our stay memorable."
United States
Lisa
The price is ￥25,051
￥28,432 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Washington Duke Inn & Golf Club
Meeting facility
Hilton Garden Inn Durham/University Medical Center

Hilton Garden Inn Durham/University Medical Center

Hilton Garden Inn Durham/University Medical Center
3.0 star property
9th Street District, 3.4 km from Museum of Life and Science
9.2 out of 10, Wonderful, (1000)
"Just right for an overnight business trip "
United States
Cody
The price is ￥15,070
￥17,105 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hilton Garden Inn Durham/University Medical Center
Courtyard
Residence Inn Durham McPherson/Duke University Medical Cntr

Residence Inn Durham McPherson/Duke University Medical Cntr

Residence Inn Durham McPherson/Duke University Medical Cntr
3.0 star property
Trinity Park, 3.3 km from Museum of Life and Science
9.2 out of 10, Wonderful, (461)
"Hotel was great - very friendly staff."
United States
Lisa
The price is ￥20,964
￥23,794 total
includes taxes & fees
Jan 27 - Jan 28, 2026
Residence Inn Durham McPherson/Duke University Medical Cntr
Property grounds
Rizzo Center, a Destination by Hyatt Hotel

Rizzo Center, a Destination by Hyatt Hotel

Rizzo Center, a Destination by Hyatt Hotel
4.0 star property
16.3 km from Museum of Life and Science
9.6 out of 10, Exceptional, (1000)
"Breakfast was fabulous!"
United States
Cindy
The price is ￥23,822
￥27,037 total
includes taxes & fees
Dec 29 - Dec 30
Rizzo Center, a Destination by Hyatt Hotel
Terrace/patio
SpringHill Suites by Marriott Durham City View

SpringHill Suites by Marriott Durham City View

SpringHill Suites by Marriott Durham City View
3.5 star property
4.6 km from Museum of Life and Science
9.2 out of 10, Wonderful, (457)
"Extremely clean room, nice fragrance throughout the hotel, and friendly staff."
United States
Mary
The price is ￥14,718
￥16,704 total
includes taxes & fees
Jan 4 - Jan 5, 2026
SpringHill Suites by Marriott Durham City View
BBQ/picnic area
AC Hotel Durham

AC Hotel Durham

AC Hotel Durham
3.0 star property
4.9 km from Museum of Life and Science
9.2 out of 10, Wonderful, (621)
"Room was very clean, staff very helpful and nice. "
United States
Tia
The price is ￥18,499
￥20,996 total
includes taxes & fees
Jan 4 - Jan 5, 2026
AC Hotel Durham
Terrace/patio
The Colonial Inn, an Ascend Collection Hotel

The Colonial Inn, an Ascend Collection Hotel

The Colonial Inn, an Ascend Collection Hotel
4.0 star property
18.9 km from Museum of Life and Science
9.6 out of 10, Exceptional, (266)
"The room was great. Very clean. The staff was absolutely amazing! 10 out of 10! "
United States
Stuart
The price is ￥21,027
￥23,866 total
includes taxes & fees
Jan 18 - Jan 19, 2026
The Colonial Inn, an Ascend Collection Hotel
Outdoor pool, sun loungers
Hyatt Place Durham Southpoint

Hyatt Place Durham Southpoint

Hyatt Place Durham Southpoint
3.0 star property
15.3 km from Museum of Life and Science
9.4 out of 10, Exceptional, (1001)
"Beautiful room and very clean. Staff were extremely nice on each shift. Will stay here again!"
United States
Jacoby
The price is ￥19,102
￥21,681 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hyatt Place Durham Southpoint
Premium bedding, desk, blackout drapes, iron/ironing board
The Durham Hotel

The Durham Hotel

The Durham Hotel
4.0 star property
Downtown Durham, 3.6 km from Museum of Life and Science
9.0 out of 10, Wonderful, (645)
"Great stay. Very nice boutique hotel. "
United States
nadav
The price is ￥29,124
￥33,055 total
includes taxes & fees
Jan 1 - Jan 2, 2026
The Durham Hotel
Minibar, desk, blackout drapes, iron/ironing board
Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek
2.5 star property
17.5 km from Museum of Life and Science
9.4 out of 10, Exceptional, (1006)
"Wonderful hotel "
United States
Robert
The price is ￥17,204
￥19,483 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek
Property amenity
Aloft Durham Downtown

Aloft Durham Downtown

Aloft Durham Downtown
3.0 star property
American Tobacco District, 4.1 km from Museum of Life and Science
9.0 out of 10, Wonderful, (731)
"Very friendly staff, very clean and convenient location"
United States
Robert
The price is ￥29,122
￥33,054 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Aloft Durham Downtown
Meeting facility
The Westin Raleigh-Durham Airport

The Westin Raleigh-Durham Airport

The Westin Raleigh-Durham Airport
4.0 star property
17.4 km from Museum of Life and Science
9.4 out of 10, Exceptional, (281)
"Spotless, comfortable room. Staff very friendly and accomodated ourcrequest for a very laye check out. Room was spacious, modern yet homey"
United States
Cheryl
The price is ￥30,844
￥34,932 total
includes taxes & fees
Jan 3 - Jan 4, 2026
The Westin Raleigh-Durham Airport
Property amenity
Towneplace Suites By Marriott Raleigh-Durham Airport/Morrisville

Towneplace Suites By Marriott Raleigh-Durham Airport/Morrisville

Towneplace Suites By Marriott Raleigh-Durham Airport/Morrisville
3.0 star property
19.8 km from Museum of Life and Science
9.4 out of 10, Exceptional, (137)
"Check in was easy, very attentive staff. Excellent rooms, very clean, and very resonably priced for a very nice property. "
United States
Steve
The price is ￥15,031
￥17,023 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Towneplace Suites By Marriott Raleigh-Durham Airport/Morrisville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Museum of Life and Science Hotel Reviews

Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University

10/10 Excellent
"I was pleased when we finally got the broom that I requested from last time"
Stephen 1-night trip
Posted 2 days ago
Comfort Inn & Suites Durham near Duke University

Hotels near other Museum of Life and Science attractions

Brightleaf Square

You can browse for the perfect souvenirs at Brightleaf Square during your visit to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area.
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Vietnam Veterans Living Memorial

You can find out about the history of Durham with a visit to Vietnam Veterans Living Memorial. Attend a sporting event or visit the stunning cathedral in this family-friendly area.
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Frequently asked questions

What's the area like around Museum of Life and Science?
Museum of Life and Science is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Museum of Life and Science?
Hampton Inn & Suites Durham/North I-85 is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.8 mi (1.4 km) from Museum of Life and Science. Other good options within 5 miles include Holiday Inn Express Durham by IHG and Red Roof Inn Durham - Duke Univ Medical Center.
How many hotels will I find close to Museum of Life and Science?
Expedia has 10 hotels and other accommodations within a mile from Museum of Life and Science.
If I need to cancel the hotel reservation for my stay near Museum of Life and Science, will I receive a refund?
Yes, most hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to view the best deals near Museum of Life and Science.
Where can I learn more about changing or cancelling my trip in the area near Museum of Life and Science?
To access more information about picking new dates or cancelling your stay near Museum of Life and Science, go to https://www.expedia.com/service/.
What can I see and do near Museum of Life and Science?
You'll want to browse the exhibits at Nasher Museum of Art at Duke University and Bennett Place. Explore landmarks like American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium. You can watch performances at Carolina Theatre, Durham Performing Arts Center, and Manbites Dog Theater if you're interested in local theater.