Find hotels near Museum of Life and Science, Raleigh from ￥10,661

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Our top choices for Museum of Life and Science hotels

Free daily buffet breakfast
Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85
2.5 star property
1.4 km from Museum of Life and Science
9.0 out of 10, Wonderful, (1003)
"Nice place to stay and close to everything. "
United States
Christy
The price is ￥16,687
￥18,938 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hampton Inn & Suites Durham/North I-85
Free buffet breakfast
Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG
2.5 star property
2.2 km from Museum of Life and Science
8.8 out of 10, Excellent, (956)
"Room was great"
United States
Barbara
The price is ￥15,302
￥17,369 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Holiday Inn Express Durham by IHG
Premium bedding, desk, blackout drapes, iron/ironing board
Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University
2.5 star property
Croasdaile Farm Master, 3.2 km from Museum of Life and Science
8.6 out of 10, Excellent, (1004)
"Friendly staff, clean room, nice breakfast"
United States
Jessica
The price is ￥14,729
￥16,717 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Comfort Inn & Suites Durham near Duke University
Lobby
Red Roof Inn Durham - Duke Univ Medical Center

Red Roof Inn Durham - Duke Univ Medical Center

Red Roof Inn Durham - Duke Univ Medical Center
2.0 star property
2.2 km from Museum of Life and Science
6.8 out of 10, (1003)
"Good motel...clean, easy acess "
United States
Howard
The price is ￥9,156
￥10,661 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Red Roof Inn Durham - Duke Univ Medical Center
Terrace/patio
Hampton Inn & Suites Durham University Medical Center

Hampton Inn & Suites Durham University Medical Center

Hampton Inn & Suites Durham University Medical Center
2.5 star property
4.8 km from Museum of Life and Science
9.6 out of 10, Exceptional, (398)
"Great breakfast, clean rooms and beds "
United States
Fabiola B
The price is ￥17,982
￥20,409 total
includes taxes & fees
Dec 29 - Dec 30
Hampton Inn & Suites Durham University Medical Center
Reception
Hilton Garden Inn Durham/University Medical Center

Hilton Garden Inn Durham/University Medical Center

Hilton Garden Inn Durham/University Medical Center
3.0 star property
9th Street District, 3.4 km from Museum of Life and Science
9.2 out of 10, Wonderful, (1001)
"Just right for an overnight business trip "
United States
Cody
The price is ￥12,754
￥14,477 total
includes taxes & fees
Dec 28 - Dec 29
Hilton Garden Inn Durham/University Medical Center
Exterior
JB Duke Hotel

JB Duke Hotel

JB Duke Hotel
4.0 star property
5.6 km from Museum of Life and Science
9.4 out of 10, Exceptional, (542)
"Excellent on all levels! Will definitely stay here again!"
United States
Cherie Nan
The price is ￥23,505
￥26,679 total
includes taxes & fees
Dec 24 - Dec 25
JB Duke Hotel
Front of property
Washington Duke Inn & Golf Club

Washington Duke Inn & Golf Club

Washington Duke Inn & Golf Club
4.0 star property
5.9 km from Museum of Life and Science
9.4 out of 10, Exceptional, (1003)
"Everything fabulous!"
United States
Terri
The price is ￥24,989
￥28,363 total
includes taxes & fees
Dec 25 - Dec 26
Washington Duke Inn & Golf Club
Carolina Log Cabin | Terrace/patio
Arrowhead Inn

Arrowhead Inn

Arrowhead Inn
4.5 star property
9.8 km from Museum of Life and Science
9.8 out of 10, Exceptional, (119)
"Bed was very comfortable, breakfast was yummy, and the surroundings were beautiful"
United States
Ronald
The price is ￥30,951
￥35,128 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Arrowhead Inn
Lobby
AC Hotel Durham

AC Hotel Durham

AC Hotel Durham
3.0 star property
4.9 km from Museum of Life and Science
9.2 out of 10, Wonderful, (617)
"Room was very clean, staff very helpful and nice. "
United States
Tia
The price is ￥18,638
￥21,154 total
includes taxes & fees
Dec 25 - Dec 26
AC Hotel Durham
Exterior
SpringHill Suites by Marriott Durham City View

SpringHill Suites by Marriott Durham City View

SpringHill Suites by Marriott Durham City View
3.5 star property
4.6 km from Museum of Life and Science
9.2 out of 10, Wonderful, (455)
"Yess the room was spotless and clean the check in was smooth "
United States
Vonisha
The price is ￥16,225
￥18,415 total
includes taxes & fees
Dec 28 - Dec 29
SpringHill Suites by Marriott Durham City View
Outdoor dining
The Durham Hotel

The Durham Hotel

The Durham Hotel
4.0 star property
Downtown Durham, 3.6 km from Museum of Life and Science
9.0 out of 10, Wonderful, (641)
"Great stay. Very nice boutique hotel. "
United States
nadav
The price is ￥29,343
￥33,304 total
includes taxes & fees
Dec 25 - Dec 26
The Durham Hotel
Front of property
Aloft Durham Downtown

Aloft Durham Downtown

Aloft Durham Downtown
3.0 star property
American Tobacco District, 4.1 km from Museum of Life and Science
9.0 out of 10, Wonderful, (731)
"Very friendly staff, very clean and convenient location"
United States
Robert
The price is ￥25,343
￥28,763 total
includes taxes & fees
Dec 29 - Dec 30
Aloft Durham Downtown
Hallway
University Inn Durham next to Duke University Medical Center

University Inn Durham next to Duke University Medical Center

University Inn Durham next to Duke University Medical Center
2.0 star property
4 km from Museum of Life and Science
8.8 out of 10, Excellent, (1001)
"Great place"
United States
Chase
The price is ￥16,895
￥19,178 total
includes taxes & fees
Dec 24 - Dec 25
University Inn Durham next to Duke University Medical Center
Property grounds
Rizzo Center, a Destination by Hyatt Hotel

Rizzo Center, a Destination by Hyatt Hotel

Rizzo Center, a Destination by Hyatt Hotel
4.0 star property
16.3 km from Museum of Life and Science
9.6 out of 10, Exceptional, (1001)
"Friendly staff, beautiful grounds to explore and excellent accommodations."
United States
Jason
The price is ￥23,197
￥26,329 total
includes taxes & fees
Dec 26 - Dec 27
Rizzo Center, a Destination by Hyatt Hotel
Outdoor pool, sun loungers
Hyatt Place Durham Southpoint

Hyatt Place Durham Southpoint

Hyatt Place Durham Southpoint
3.0 star property
15.3 km from Museum of Life and Science
9.4 out of 10, Exceptional, (1002)
"Great stay"
United States
Zaleena
The price is ￥19,246
￥21,843 total
includes taxes & fees
Dec 29 - Dec 30
Hyatt Place Durham Southpoint
Restaurant
The Colonial Inn, an Ascend Collection Hotel

The Colonial Inn, an Ascend Collection Hotel

The Colonial Inn, an Ascend Collection Hotel
4.0 star property
18.9 km from Museum of Life and Science
9.6 out of 10, Exceptional, (265)
"The room was great. Very clean. The staff was absolutely amazing! 10 out of 10! "
United States
Stuart
The price is ￥21,186
￥24,046 total
includes taxes & fees
Jan 11 - Jan 12, 2026
The Colonial Inn, an Ascend Collection Hotel
Lobby
Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek
2.5 star property
17.5 km from Museum of Life and Science
9.4 out of 10, Exceptional, (1000)
"Wonderful hotel "
United States
Robert
The price is ￥17,334
￥19,631 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek
Interior entrance
21c Museum Hotel Durham

21c Museum Hotel Durham

21c Museum Hotel Durham
4.0 star property
Downtown Durham, 3.7 km from Museum of Life and Science
8.4 out of 10, Very Good, (1000)
"Amazing staff, comfortable rooms, best shower, convenient location. "
United States
Lauren
The price is ￥25,343
￥29,553 total
includes taxes & fees
Jan 11 - Jan 12, 2026
21c Museum Hotel Durham
Lobby sitting area
The Lodge at Duke Medical Center

The Lodge at Duke Medical Center

The Lodge at Duke Medical Center
3.0 star property
4 km from Museum of Life and Science
8.4 out of 10, Very Good, (1001)
"Room was clean and great customer service. "
United States
Anne
The price is ￥20,350
￥23,096 total
includes taxes & fees
Dec 24 - Dec 25
The Lodge at Duke Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Museum of Life and Science Hotel Reviews

Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University

10/10 Excellent
"Friendly staff, clean room, nice breakfast"
Jessica 1-night trip
Posted 1 day ago
Comfort Inn & Suites Durham near Duke University

Hotels near other Museum of Life and Science attractions

Brightleaf Square

You can browse for the perfect souvenirs at Brightleaf Square during your visit to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area.
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Vietnam Veterans Living Memorial

You can find out about the history of Durham with a visit to Vietnam Veterans Living Memorial. Attend a sporting event or visit the stunning cathedral in this family-friendly area.
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Frequently asked questions

What's the area like around Museum of Life and Science?
Museum of Life and Science is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 9 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Museum of Life and Science?
Hampton Inn & Suites Durham/North I-85 is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.8 mi (1.4 km) from Museum of Life and Science. Other good options within 5 miles include Holiday Inn Express Durham by IHG and Comfort Inn & Suites Durham near Duke University.
How many hotels will I find close to Museum of Life and Science?
Expedia has 9 hotels and other accommodations within a mile from Museum of Life and Science.
If I need to cancel the hotel reservation for my stay near Museum of Life and Science, will I receive a refund?
Yes, most hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to view the best deals near Museum of Life and Science.
Where can I learn more about changing or cancelling my trip in the area near Museum of Life and Science?
To access more information about picking new dates or cancelling your stay near Museum of Life and Science, go to https://www.expedia.com/service/.
What can I see and do near Museum of Life and Science?
You'll want to browse the exhibits at Nasher Museum of Art at Duke University and Bennett Place. Explore landmarks like American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium. You can watch performances at Carolina Theatre, Durham Performing Arts Center, and Manbites Dog Theater if you're interested in local theater.