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Residence Inn Durham McPherson/Duke University Medical Cntr

3.0 star property
Travelers find a welcoming home base near Duke University, where they can warm up by the lobby fireplace after exploring the prestigious campus nearby

Choose dates to view prices

Residence Inn Durham McPherson/Duke University Medical Center offers a refreshed retreat with practical comforts. Enjoy a to-go breakfast, relax by the lobby fireplace, and request complimentary grocery shopping. WiFi in all rooms and an area shuttle make attractions accessible.

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Pet friendly
  • Free WiFi
  • Air conditioning
The current price is ￥20,737
￥23,536 total
includes taxes & fees
Aug 9 - Aug 10

Room options

Available filters for rooms
Showing 10 of 10 rooms

View all photos for Suite, 1 Bedroom

32-inch Smart TV with cable channels, TV, Netflix

Suite, 1 Bedroom

8.8 out of 10
Excellent
(6 reviews)
  • 44 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed
  • Free WiFi

View all photos for Studio, 1 King Bed with Sofa bed

A modern hotel room with a bed, a desk, a chair, a television, and a small table.

Studio, 1 King Bed with Sofa bed

9.0 out of 10
Wonderful
(37 reviews)
  • 45 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio, 1 Queen Bed with Sofa bed

A modern hotel room with a bed, a TV, a kitchenette, and a dining area.

Studio, 1 Queen Bed with Sofa bed

9.8 out of 10
Exceptional
(16 reviews)
  • 39 sq m
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom (Hearing Accessible)

A hotel room with a bed, a desk, a chair, and a TV.

Suite, 1 Bedroom (Hearing Accessible)

8.8 out of 10
Excellent
(3 reviews)
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed
  • Free WiFi

View all photos for Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

A modern hotel room with a bed, a desk, a chair, a television, and a small table.

Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

10.0 out of 10
Exceptional
(2 reviews)
  • 44 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

A modern hotel room with a bed, a desk, a chair, a television, and a small table.

Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

  • 45 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio, 1 King Bed with Sofa bed (Hearing Accessible)

A modern hotel room with a bed, a desk, a chair, a television, and a small table.

Studio, 1 King Bed with Sofa bed (Hearing Accessible)

  • 45 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

A hotel room with a bed, a desk, a chair, and a TV.

Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

  • 40 sq m
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, Multiple Beds (Mobility Accessible, Tub)

A hotel room with two beds, a flat-screen TV mounted on the wall, a wooden headboard, and a window with sheer curtains.

Suite, Multiple Beds (Mobility Accessible, Tub)

8.0 out of 10
Very good
(3 reviews)
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom (Mobility Accessible, Roll-in Shower)

A hotel room with a bed, a desk, a chair, and a TV.

Suite, 1 Bedroom (Mobility Accessible, Roll-in Shower)

10.0 out of 10
Exceptional
(1 review)
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed
  • Free WiFi

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About the neighborhood

Located in Trinity Park, a neighborhood in Durham, Residence Inn Durham McPherson/Duke University Medical Cntr is near a train station. Streets at Southpoint Mall and Brier Creek Commons are worth checking out if shopping is on the agenda, while those wishing to experience the area's popular attractions can visit Durham Performing Arts Center. Sarah P. Duke Gardens and Mary Lou Williams Center for Black Culture are also worth visiting. Visit our Durham travel guide
Map
27701, NC, Durham, 1108 West Main Street

What's nearby

  • A cobblestone street lined with brick buildings, benches, and trees.
    Brightleaf Square
    3 min walk - 0.3 km
  • A large Gothic-style cathedral with intricate stonework and multiple spires.
    Duke University
    3 min walk - 0.3 km
  • Durham Convention Center
    12 min walk - 1.1 km
  • Durham Performing Arts Center
    16 min walk - 1.4 km
  • Durham Bulls Athletic Park
    18 min walk - 1.5 km

Getting around

  • Durham Station
    8 min walk
  • Raleigh-Durham International Airport (RDU)
    21 min drive

Restaurants

  • The Federal
    3 min walk
  • Atomic Clock Brewing Co
    11 min walk
  • Grub Durham
    12 min walk
  • The Can Opener
    7 min walk
  • It's A Southern Thing
    7 min walk

About this property

Residence Inn Durham McPherson/Duke University Medical Cntr

  • Hotel remodeled in 2024 and located near Duke University
  • Located close to Durham Performing Arts Center, Residence Inn Durham McPherson/Duke University Medical Cntr provides free to-go breakfast, a free grocery shopping service, and a terrace. In addition to dry cleaning/laundry services and a fireplace in the lobby, guests can connect to free in-room WiFi.
  • Other perks include:
    • A free area shuttle, self parking (surcharge), and express check-out
    • Express check-in, a computer station, and wedding services
    • Concierge services, luggage storage, and laundry services
    • Guest reviews speak highly of the helpful staff
  • Room features
  • All 147 rooms include comforts such as laptop-friendly workspaces and air conditioning, in addition to thoughtful touches like free WiFi and desk chairs.
  • Extra conveniences in all rooms include:
    • Recycling and LED light bulbs
    • Shower/tub combinations, free toiletries, and hair dryers
    • 32-inch Smart TVs with Netflix and premium channels
    • Wardrobes/closets, separate sitting areas, and kitchens

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Aug 9 - Aug 10
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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free area shuttle
  • Self parking on site (USD 15 per day)
  • Wheelchair-accessible parking available

Food and drink

  • Free on-the-go breakfast available daily 7:00 AM to 9:00 AM
  • Coffee and tea in common areas

Things to do

  • 24-hour gym

Family friendly

  • Dining table
  • Free area shuttle
  • Grocery/convenience store
  • In-room full-sized refrigerator/freezer
  • In-room kitchen
  • In-room microwave
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Free grocery shopping service
  • Housekeeping (daily)
  • Wedding services

Business services

  • 2,530 square feet of conference space
  • Business center
  • Computer station

Outdoors

  • Terrace

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • 7 accessible parking spaces
  • Assistive listening devices in meeting rooms
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Hardwood flooring in room
  • Lever door handles
  • Thin carpet in room
  • Visual alarms in hallways
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible registration desk (34 inches high)
  • Wheelchair-accessible restaurant

More

  • 5 floors
  • Banquet hall
  • Built in 2015
  • Double-glazed windows
  • Fireplace in lobby
  • No plastic coffee stirrers
  • No plastic drinking straws
  • Non-plastic coffee stirrers available
  • Renovated entire property - April 2024
  • Smoking not allowed
  • Vegan dining options
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Free toiletries
  • Hair dryer
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 32-inch smart TV with premium cable channels
  • Netflix
  • Pay movies

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dining table
  • Dishwasher
  • Full-sized refrigerator/freezer
  • Kitchen
  • Microwave
  • Stovetop

More

  • Air conditioning (climate-controlled)
  • Desk
  • Desk chair
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Phone
  • Recycling
  • Safe
  • Separate sitting area
  • Water-efficient showers

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight
Express check-in available
Minimum check-in age: 21

Check-out

Check-out before noon
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 100.00 per pet (varies based on length of stay)
Service animals are welcome, and are exempt from fees
2 total (up to 100 lbs per pet)
Restrictions apply; for more information contact the property at the number on the booking confirmation

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Property payment types

Important information

Optional extras

  • Self parking fee: USD 15 per day
  • Pet fee: USD 100.00 per pet (varies based on length of stay)
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector, a fire extinguisher, and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)

We should mention

Guests under 18 years old are not allowed in the fitness facility, and guests under 18 years old are only allowed in the swimming pool and fitness facility with adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Frequently asked questions

Is Residence Inn Durham McPherson/Duke University Medical Cntr pet-friendly?

Yes, Residence Inn Durham McPherson/Duke University Medical Cntr allows pets (limit 2 total) with a maximum weight of up to 100 lbs per pet. There's a fee of USD 100.00 per pet, per stay. Service animals are exempt from fees. Some restrictions may apply, so please contact the property for more details.

How much does it cost to stay at Residence Inn Durham McPherson/Duke University Medical Cntr?

As of Aug 2, 2026, prices found for a 1-night stay for 2 adults at Residence Inn Durham McPherson/Duke University Medical Cntr on Aug 9, 2026 start from ￥20,737, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

How much is parking?

Self parking is available for USD 15 per day.

What time is check-in at Residence Inn Durham McPherson/Duke University Medical Cntr?

Check-in start time: 3 PM; Check-in end time: midnight.

What time is check-out at Residence Inn Durham McPherson/Duke University Medical Cntr?

Check-out is at noon.

Where is Residence Inn Durham McPherson/Duke University Medical Cntr located?

Located in Trinity Park, this hotel is within 1 mi (2 km) of Brightleaf Square, Duke University, and Durham Performing Arts Center. Duke University Hospital is 1.6 mi (2.6 km) away. Durham Station is 8 minutes by foot.

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

Residence Inn Durham McPherson/Duke University Medical Cntr Reviews

9.2

Wonderful

9.4

Cleanliness

9.0

Location

9.4

Staff & service

9.4

Property conditions & facilities
Rating 10 - Excellent. 331 out of 488 reviews
Rating 8 - Good. 109 out of 488 reviews
Rating 6 - Okay. 29 out of 488 reviews
Rating 4 - Poor. 8 out of 488 reviews
Rating 2 - Terrible. 11 out of 488 reviews

Reviews

Verified review

10/10 Excellent

Shelly

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was very spacious, staff very friendly
Stayed 1 night in May 2026
Verified review

8/10 Good

Sarah

Liked: Cleanliness, staff & service, amenities
Room was clean. Comfortable bed. Basic hotel breakfast. Lots of parking. Had A/C issue quickly resolved by a really nice technician. Close to 9th St where there’s lots of restaurants. Vin Rouge was delicious and JuJu. Would stay here again.
Stayed 2 nights in Jul 2026
Verified review

10/10 Excellent

Tiffany

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, spacious rooms with an extremely helpful staff! Highly recommended!!
Stayed 3 nights in Apr 2026
Verified review

8/10 Good

Robert

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent breakfast. The staff was outstanding. The room's television did not work the first night and the front desk clerk spent extensive time troubleshooting and escalating the outage. The room's heating, cooling and fan did not respond to the in-room thermostat.
Stayed 2 nights in Jul 2026
Verified review

10/10 Excellent

RICHARD

Liked: Cleanliness, staff & service, property conditions & facilities
Great downtown location
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Anna F

Liked: Cleanliness, amenities, property conditions & facilities
Courteous staff, spotless rooms, comfortable bed and pillows.
Stayed 4 nights in Dec 2025
Verified review

10/10 Excellent

Lisa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel was great - very friendly staff.
Stayed 2 nights in Sep 2025
Verified review

10/10 Excellent

David

Liked: Cleanliness, staff & service, amenities
We love this hotel. The staff is excellent and the rooms are well designed and comfortable. The breakfast is delicious.
Stayed 10 nights in Dec 2025
Verified review

10/10 Excellent

Tim

Liked: Cleanliness, staff & service, amenities
Great stay. The hotel breakfast left a little something to be desired but the room was clean, the staff was helpful. This was everything I expected.
Stayed 2 nights in Nov 2025
Verified review

10/10 Excellent

Judy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location with some incredible Restaurants nearby
Stayed 3 nights in Oct 2024
Verified review

10/10 Excellent

Margaret

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great and reasonably priced place to stay as a family in the center of Durham.
Stayed 1 night in Sep 2024
Verified review

10/10 Excellent

Wendy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, friendly, great location.
Stayed 1 night in Sep 2024
Verified review

10/10 Excellent

Hong

Liked: Cleanliness, staff & service, property conditions & facilities
Nice staff, very helpful. Close to Duke University, great place to stay.
Stayed 6 nights in Jan 2025
Verified review

10/10 Excellent

LaMeesha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I am thankful for the very hospitable staff that I encountered at the hotel. Everyone was smiling at the front desk every time I passed by.
Stayed 8 nights in Jun 2025
Verified review

8/10 Good

Heman

Liked: Cleanliness, amenities, property conditions & facilities
Laura and Tiffany were extremely helpful and accommodating. The whole staff was very friendly and welcoming!
Stayed 9 nights in Jul 2025
Verified review

10/10 Excellent

Mustafa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
comfortable stay
Stayed 3 nights in Nov 2023
Verified review

10/10 Excellent

Timmy

Liked: Cleanliness, amenities, property conditions & facilities
It was very clean and the staff was excellent. The stay was really good. The attendant was great at checking.
Stayed 1 night in Jun 2025
Verified review

10/10 Excellent

Timothy

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great location in Durham!
Stayed 1 night in Apr 2024
Verified review

10/10 Excellent

Kelly

Liked: Property conditions & facilities
Very nice staff and very clean!
Stayed 1 night in Feb 2024
Verified review

4/10 Poor

zubina

Disliked: Amenities, property conditions & facilities
Close to campus Convenient breakfast Old facility Convenient parking
Stayed 2 nights in Aug 2024
Verified review

10/10 Excellent

eric

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

The place to stay!!

A very clean and quiet hotel property with great breakfast in the morning. Ample parking and reasonably priced. All of the staff were very friendly. Would definitely recommend.
Stayed 2 nights in Oct 2024
Verified review

10/10 Excellent

charles

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
A very nice hotel in the heart of Durham. Close proximity to restaurants, bars and DPAC.
Stayed 1 night in Oct 2023
Verified review

10/10 Excellent

Francis

Liked: Amenities
Great location. Friendly competent staff
Stayed 2 nights in Apr 2024
Verified review

10/10 Excellent

Verified traveler

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great value, good location, decent breakfast

Clean, walking distance to gas stations and restaurants.,, decent breakfast in the morning that was free so can't complain... free hot coffee all day... spacious and well-decorated rooms with good cable and smart tvs. All around, great value for the price
Stayed 2 nights in Jan 2025
Verified review

10/10 Excellent

Ashlee

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I liked the easy access to shops and food, as well as downtown and the interstate. Rooms were clean, breakfast was good (and free) and the staff were all exceptionally kind and helpful.
Stayed 4 nights in Jan 2024