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Discover 13,426 Matlacha Isles hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Matlacha Isles hotels

Comfort Suites Fort Myers East I-75
Property amenity

Comfort Suites Fort Myers East I-75

2.5 star property
9.6 out of 10, Exceptional, (254)
"Excellent stay. Staff was great and helpful. Would definitely recommend. 👍"
The price is ￥14,590
￥16,268 total
includes taxes & fees
Sep 7 - Sep 8
Comfort Suites Fort Myers East I-75
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Lobby

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

2.0 star property
7.8 out of 10, Good, (1425)
"Very clean, quiet, nice rooms. "
The price is ￥9,926
￥11,069 total
includes taxes & fees
Sep 1 - Sep 2
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Baymont by Wyndham Punta Gorda/Port Charlotte
Lobby

Baymont by Wyndham Punta Gorda/Port Charlotte

2.5 star property
8.2 out of 10, Very Good, (1065)
"Great spot for overnight stay!"
The price is ￥9,794
￥10,970 total
includes taxes & fees
Sep 8 - Sep 9
Baymont by Wyndham Punta Gorda/Port Charlotte
MainStay Suites Fort Myers East I-75
Property amenity

MainStay Suites Fort Myers East I-75

2.5 star property
9.4 out of 10, Exceptional, (141)
"Great location, clean and comfortable. "
The price is ￥13,749
￥15,330 total
includes taxes & fees
Sep 7 - Sep 8
MainStay Suites Fort Myers East I-75
Comfort Inn & Suites Airport
Indoor pool

Comfort Inn & Suites Airport

2.5 star property
8.6 out of 10, Excellent, (1066)
"I always stay at this hotel"
The price is ￥9,926
￥11,068 total
includes taxes & fees
Sep 7 - Sep 8
Comfort Inn & Suites Airport
Holiday Inn Express & Suites Fort Myers Airport by IHG
Free daily buffet breakfast

Holiday Inn Express & Suites Fort Myers Airport by IHG

2.5 star property
9.6 out of 10, Exceptional, (1007)
"Easy check in, courteous friendly staff."
The price is ￥13,676
￥15,249 total
includes taxes & fees
Sep 20 - Sep 21
Holiday Inn Express & Suites Fort Myers Airport by IHG
Best Western Fort Myers Waterfront
Exterior

Best Western Fort Myers Waterfront

3.0 star property
7.4 out of 10, Good, (1008)
"The view is great "
The price is ￥13,624
￥15,191 total
includes taxes & fees
Sep 1 - Sep 2
Best Western Fort Myers Waterfront
Residence Inn by Marriott Fort Myers Sanibel
Outdoor pool

Residence Inn by Marriott Fort Myers Sanibel

3.0 star property
8.6 out of 10, Excellent, (1009)
"Very pleased with my stay."
The price is ￥12,793
￥14,264 total
includes taxes & fees
Sep 1 - Sep 2
Residence Inn by Marriott Fort Myers Sanibel
Studiores Fort Myers
Laptop workspace, blackout drapes, free WiFi, bed sheets

Studiores Fort Myers

2.0 star property
The price is ￥13,087
￥14,593 total
includes taxes & fees
Sep 1 - Sep 2
Studiores Fort Myers
Hyatt Place Fort Myers/at The Forum
Exterior

Hyatt Place Fort Myers/at The Forum

3.0 star property
8.2 out of 10, Very Good, (1008)
"Very nice and friendly place "
The price is ￥17,499
￥19,512 total
includes taxes & fees
Sep 1 - Sep 2
Hyatt Place Fort Myers/at The Forum
Best Western Fort Myers Inn & Suites
Lobby

Best Western Fort Myers Inn & Suites

2.5 star property
8.6 out of 10, Excellent, (1025)
"Staff was friendly, building was great, beds were comfy"
The price is ￥10,192
￥11,364 total
includes taxes & fees
Sep 14 - Sep 15
Best Western Fort Myers Inn & Suites
Quality Suites Fort Myers I-75
Lobby

Quality Suites Fort Myers I-75

2.5 star property
8.0 out of 10, Very Good, (1001)
"Excellent rooms breakfast "
The price is ￥11,617
￥12,953 total
includes taxes & fees
Sep 1 - Sep 2
Quality Suites Fort Myers I-75
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Deluxe Studio, 1 King Bed, Marina View | View from room

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

2.5 star property
8.8 out of 10, Excellent, (1002)
"Such a great place to stay! "
The price is ￥17,073
￥19,038 total
includes taxes & fees
Sep 5 - Sep 6
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
Exterior

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

2.5 star property
9.4 out of 10, Exceptional, (985)
"Amazing hotel Great food and service"
The price is ￥12,793
￥14,264 total
includes taxes & fees
Sep 7 - Sep 8
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
Allure Suites
Interior entrance

Allure Suites

3.0 star property
7.6 out of 10, Good, (1007)
"The room was very clean "
Allure Suites
Matlacha on Shoreview
View from room

Matlacha on Shoreview

2.0 star property
9.6 out of 10, Exceptional, (190)
"Lovely little propery for the price!"
The price is ￥13,235
￥25,414 total
includes taxes & fees
Sep 1 - Sep 2
Matlacha on Shoreview
Margaritaville Beach Resort Fort Myers
Exterior

Margaritaville Beach Resort Fort Myers

4.0 star property
9.0 out of 10, Wonderful, (1418)
"Is beatifull and big hotel,I liked the pool is very big,and this hotel stay near to the beach."
The price is ￥18,116
￥25,938 total
includes taxes & fees
Sep 2 - Sep 3
Margaritaville Beach Resort Fort Myers
Suburban Studios Fort Myers Cape Coral
Lobby

Suburban Studios Fort Myers Cape Coral

2.0 star property
7.8 out of 10, Good, (649)
"Very nice place"
The price is ￥8,823
￥9,838 total
includes taxes & fees
Sep 1 - Sep 2
Suburban Studios Fort Myers Cape Coral
Extended Stay America Premier Suites - Fort Myers - Airport
Restaurant

Extended Stay America Premier Suites - Fort Myers - Airport

2.5 star property
8.8 out of 10, Excellent, (674)
"Great stay "
The price is ￥10,057
￥11,213 total
includes taxes & fees
Sep 7 - Sep 8
Extended Stay America Premier Suites - Fort Myers - Airport
Candlewood Suites Ft Myers I-75 by IHG
Interior entrance

Candlewood Suites Ft Myers I-75 by IHG

2.5 star property
8.0 out of 10, Very Good, (730)
"Great place"
The price is ￥9,852
￥10,985 total
includes taxes & fees
Sep 2 - Sep 3
Candlewood Suites Ft Myers I-75 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Matlacha Isles

Find the best Matlacha Isles areas and neighborhoods for the activities you enjoy most.

Pelican

If you're spending some time in Pelican, Tarpon Point and Harbour View Gallery are top sights worth seeing.

Cape Coral which includes a river or creek and a park

Caloosahatchee

If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.

Yacht Club

While there might not be top attractions in Yacht Club, you can explore the larger area and discover places like Cape Coral Yacht Club Beach and Veterans Foundation Headquarters.

Mariner

While visiting Mariner, you might make a stop by sights like Mike Greenwell's Bat-A-Ball & Family Fun Park and Yucca Pens Unit State Wildlife Management Area.

North Fort Myers showing a sandy beach, general coastal views and a coastal town

Hancock

While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.

Top Matlacha Isles Hotel Reviews

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Frequently asked questions

What is Matlacha Isles like?

Travelers will be sure to find plenty to entertain them in Cape Coral's Matlacha Isles neighborhood.

How many hotels will I be able to find in the Matlacha Isles area?

When you want to kick up your feet after a day of exploring the sights in Cape Coral, you can choose from 17 Expedia hotels and other accommodations in Matlacha Isles.

If I need to cancel my hotel reservation in Matlacha Isles, will I receive a refund?

Yes, you'll find most hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, it may still be possible to cancel it and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the best deals available in Matlacha Isles.

Where can I learn more about changing or cancelling my trip to Matlacha Isles?

To find more details about changing or cancelling your trip to Matlacha Isles, go to https://www.expedia.com/service/.

What are the top things to see and do in Matlacha Isles?

A few places to visit in the area around Matlacha Isles include Griffen American Center for Haitian Art, Lovegrove Gallery & Gardens, and Royal Tee Golf Club. While you're out sightseeing in Cape Coral, be sure to visit other sights like Little Dead Key or Big Dead Key.