Matlacha Isles Vacations

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Where to stay in Matlacha Isles

Find the best Matlacha Isles areas and neighborhoods for the activities you enjoy most. Learn more about Matlacha Isles

Matlacha Isles Hotel Deals

Lani Kai Beachfront Resort
Lani Kai Beachfront Resort
3.5 out of 5
1400 Estero Blvd, Fort Myers Beach, FL
Fully refundableReserve now, pay when you stay
The price is ¥21,671 per night from Jun 30 to Jul 1
¥21,671
¥30,306 total
Jun 30 - Jul 1
includes taxes & fees
8.4/10 Very Good! (1,003 reviews)
"Recovering nicely from the hurricane. Would of loved less music in the evenings to sit on balcony."

Reviewed on Jun 26, 2025

Lani Kai Beachfront Resort
Margaritaville Beach Resort Fort Myers
Margaritaville Beach Resort Fort Myers
4 out of 5
251 Crescent Street, Fort Myers Beach, FL
The price is ¥31,863 per night from Jul 1 to Jul 2
¥31,863
¥41,185 total
Jul 1 - Jul 2
includes taxes & fees
8.8/10 Excellent! (1,190 reviews)
"The atmosphere and layout of the resort is just perfect!! The rooms where cozy and clean!"

Reviewed on Jun 25, 2025

Margaritaville Beach Resort Fort Myers
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 out of 5
1538 Cape Coral Pkwy E, Cape Coral, FL
Fully refundable
The price is ¥15,101 per night from Jun 29 to Jun 30
¥15,101
¥16,837 total
Jun 29 - Jun 30
includes taxes & fees
9/10 Wonderful! (1,013 reviews)
"My only complaint was that when we were sitting by the pool, which was on smoking, the staff would be right outside the pool area smoking so we still got to smell their cigarettes."

Reviewed on Jun 23, 2025

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Matlacha Isles vacation package cost?
Our Matlacha Isles vacation packages, which begin from just , are the best way to save loads of cash. Select your favorite flights, hotels and rental cars to create a custom-built itinerary.
How do I get a cheap travel package to Matlacha Isles?
Combine your hotel and flight bookings, add on extras such as activities, and save with a Matlacha Isles vacation package. You won't just walk away with awesome discounts on your trip --- you'll have loads of choice at your fingertips too. When you book through Expedia, you'll have your pick of over 550 partner airlines and 1,000,000 hotels around the globe. Your next epic adventure begins right here, right now!
Where should I stay in Matlacha Isles?
If you're itching to be where the action is, stay near Sun Splash Water Park. Many happy campers book a hotel around this renowned tourist attraction.
What are the top hotels in Matlacha Isles?
Reserve a room at The Perfect Day In Matlacha Direct Gulf Access. It's one of the neighborhood's most popular hotels. Another highly rated option in Matlacha Isles is Fun'n Sun - Charming 3 Br/ 3 Baths Waterfront Villa W. Boat Lift.
How far in advance should I book my Matlacha Isles vacation?
Smart travelers will likely want to reserve their seats early. You can normally start comparing international fares on Expedia up to a year before your intended flight. If you've left things to the last minute, don't stress. Low prices occasionally become available just weeks prior to departure.
What does an Expedia Matlacha Isles travel package include?
Expedia has all you need to organize your Matlacha Isles trip, but how you structure your package depends on you. Select from a combination of rental cars, hotels and flights. Chasing some experiences or tours to keep you busy? Once you've made your booking, you can add them on too. No matter your budget, there's a deal to suit your needs.
What should I know before booking a Matlacha Isles travel package?
Bundling your bookings into a Matlacha Isles vacation package is the easiest way to organize your trip. Not only that, you'll save just for combining your hotels, flights and car rentals. Once you've booked, why not add on a day tour or an activity?
Can I choose my airline with a Matlacha Isles Expedia vacation package?
Yes, definitely. Expedia has more than 550 partner airlines to select from globally. With all that choice, finding the ideal carrier to bring you to Matlacha Isles will be easy.
If I'm not able to travel, can I cancel my Matlacha Isles vacation package?
Don't worry if you're rethinking your Matlacha Isles vacation package --- you can cancel or change your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur charges from your airline, hotel or car rental company. We get that your circumstances can suddenly change, so look up our Customer Service Portal if that happens. When you're ready to make changes, we're ready to help.

Discover the most popular places to visit in Matlacha Isles

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.