Hotels near Main Street-Science World Station

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Main Street-Science World Station hotels

Smithe House

Smithe House
4.0 star property
Yaletown, 1.3 km from Main Street-Science World Station
10.0 out of 10, Exceptional, (350)
"Everything was perfect staff were amazing location perfect apartment was spotless "
Australia
Andrea
The price is ¥22,441
¥26,744 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Smithe House

L'Hermitage Hotel

L'Hermitage Hotel
4.0 star property
Downtown Vancouver, 1.5 km from Main Street-Science World Station
9.8 out of 10, Exceptional, (1005)
"Great stay"
Canada
Edwin
The price is ¥25,716
¥30,647 total
includes taxes & fees
Dec 22 - Dec 23
L'Hermitage Hotel

Wedgewood Hotel & Spa

Wedgewood Hotel & Spa
5.0 star property
Downtown Vancouver, 1.9 km from Main Street-Science World Station
9.8 out of 10, Exceptional, (1326)
"Beautiful small boutique hotel"
United States
Alastair
The price is ¥27,413
¥33,079 total
includes taxes & fees
Dec 22 - Dec 23
Wedgewood Hotel & Spa

Loden Hotel

Loden Hotel
4.5 star property
Coal Harbour, 2.4 km from Main Street-Science World Station
9.8 out of 10, Exceptional, (1001)
"Room was beautiful and staff were great!"
United States
Teresa
The price is ¥52,461
¥63,308 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Loden Hotel

Hotel Blu Vancouver

Hotel Blu Vancouver
4.0 star property
Downtown Vancouver, 1.2 km from Main Street-Science World Station
9.6 out of 10, Exceptional, (3469)
"Nice clean rooms, great location."
Canada
Halyna
The price is ¥23,289
¥28,104 total
includes taxes & fees
Dec 24 - Dec 25
Hotel Blu Vancouver

EXchange Hotel Vancouver

EXchange Hotel Vancouver
4.0 star property
Downtown Vancouver, 1.8 km from Main Street-Science World Station
9.6 out of 10, Exceptional, (3055)
"The staff are amazing; great location! "
Canada
Lareina
The price is ¥21,602
¥26,067 total
includes taxes & fees
Jan 4 - Jan 5, 2026
EXchange Hotel Vancouver

OPUS Hotel Vancouver

OPUS Hotel Vancouver
4.0 star property
Yaletown, 1.6 km from Main Street-Science World Station
9.6 out of 10, Exceptional, (1057)
"Room, service, amenities, and location were all excellent"
Canada
Matt
OPUS Hotel Vancouver

Executive Hotel Le Soleil

Executive Hotel Le Soleil
4.0 star property
Downtown Vancouver, 1.9 km from Main Street-Science World Station
9.6 out of 10, Exceptional, (2831)
"Front desk staff are great, the room was spotless, and the bed was fantastic."
Canada
Martin
The price is ¥19,316
¥23,309 total
includes taxes & fees
Dec 22 - Dec 23
Executive Hotel Le Soleil

AZUR Legacy Collection Hotel

AZUR Legacy Collection Hotel
4.5 star property
Downtown Vancouver, 1.8 km from Main Street-Science World Station
9.6 out of 10, Exceptional, (1600)
"Fabulous place, everything was great. "
United States
Denis
The price is ¥25,488
¥30,756 total
includes taxes & fees
Jan 11 - Jan 12, 2026
AZUR Legacy Collection Hotel

Rosewood Hotel Georgia

Rosewood Hotel Georgia
5.0 star property
Downtown Vancouver, 1.8 km from Main Street-Science World Station
9.6 out of 10, Exceptional, (1073)
"Beautiful hotel, great location.Friendly staff"
United States
Magdalena
The price is ¥56,679
¥68,397 total
includes taxes & fees
Jan 17 - Jan 18, 2026
Rosewood Hotel Georgia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Main Street-Science World Station Hotel Reviews

Find out more about Main Street-Science World Station

Main Street-Science World Station hotels information

Number of reviews
16,737
Accommodation
1,582 hotels
Lowest Price
¥23,309
Highest Price
¥68,397

Frequently asked questions

What's the area like around Main Street-Science World Station?

Main Street-Science World Station is located in a vibrant area of Vancouver known for its beautiful beaches and major shopping area. If you're looking for a convenient place to stay, check out the 296 hotels and other accommodations located within a mile of the station.

What's the best place to stay near Main Street-Science World Station?

Sandman Hotel Vancouver Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers 2 restaurants and 2 bars. It's located just a short 0.7 mi (1.1 km) from Main Street-Science World Station. Other good options within 5 miles include Paradox Vancouver and Pinnacle Hotel Harbourfront.

How many hotels are there near Main Street-Science World Station?

Expedia has 296 hotels and other accommodations within a mile from the station.

What can I see and do near Main Street-Science World Station?

You'll want to browse the collections at Science World, Vancouver Art Gallery, and Museum of Vancouver. While you're exploring, swing by Hotel Europe, Chinatown Millennium Gate, and Woodward's to learn a bit about the area. You can watch performances at Rickshaw Theatre, Vancouver Playhouse, and Queen Elizabeth Theatre if you're interested in local theater.