Uptown - Upper Duval, FL

Key West

Key West Butterfly and Nature Conservatory featuring zoo animals, animals and flowers
Key West Butterfly and Nature Conservatory showing zoo animals, animals and flowers
South Beach which includes a beach and a coastal town as well as a large group of people
South Beach showing a beach, swimming and a luxury hotel or resort
Key West Butterfly and Nature Conservatory featuring signage

Popular places to visit

Southernmost Point featuring signage as well as a large group of people

Southernmost Point

4.5/5(3,182 reviews)

Snap a memorable photograph from the edge of North America at this monumental landmark.

Southernmost Point
South Beach featuring a sandy beach and general coastal views as well as a small group of people

South Beach

4/5(980 reviews)

The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.

South Beach
Key West Butterfly and Nature Conservatory showing animals, zoo animals and food

Key West Butterfly and Nature Conservatory

4.5/5(760 reviews)

With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.

Key West Butterfly and Nature Conservatory

Things to do

Florida: Key West Overseas Highway Self-Driving Tour

Florida: Key West Overseas Highway App-Based Driving Audio Tour

￥2,088
per traveler
78% of travellers recommend
Florida: Key West Overseas Highway App-Based Driving Audio Tour
Bahama Village Walking Tour

Bahama Village Walking Tour

￥4,277
per adult
Bahama Village Walking Tour
Key West’s Old Town Treasures: A Self-Guided Audio Tour

Key West’s Old Town Treasures: A Self-Guided Audio Tour

￥2,137
per adult
Key West’s Old Town Treasures: A Self-Guided Audio Tour
Florida Key West Self-Guided Walking Audio Tour

Florida Key West Self-Guided Walking Audio Tour Via App

￥1,424
per traveler
Florida Key West Self-Guided Walking Audio Tour Via App
Southernmost Point in the Continental USA!

PRIVATE Welcome to Key West Walking Tour

￥39,204
per adult
PRIVATE Welcome to Key West Walking Tour
Key West History And Culture Walking Tour

Southernmost Key West History and Culture Small-Group Walking Tour

￥5,701
per adult
Southernmost Key West History and Culture Small-Group Walking Tour
See all activities in Key West

Uptown - Upper Duval Hotel Deals

Southernmost Beach Resort and Guesthouses
Southernmost Beach Resort and Guesthouses
4 out of 5
1319 Duval Street, Key West, FL
The price is ￥32,943 per night from Jun 29 to Jun 30
￥32,943
￥46,786 total
Jun 29 - Jun 30
includes taxes & fees
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,505 reviews)
"Great location. We had ocean view. The multiple pools were great. Would prefer a microwave in room. Add hooks to hang wet towels and bath suits. Overall experience was fantastic"

Reviewed on Jun 13, 2025

Southernmost Beach Resort and Guesthouses
The Southernmost Inn - Adults Only
The Southernmost Inn - Adults Only
3 out of 5
525 United Street, Key West, FL
Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8/10 Very Good! (1,099 reviews)
"Great location, 1 block from Duval St. Nice pools, nice size room and great breakfast every morning. Will stay there again next time."

Reviewed on Jun 14, 2025

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The Southernmost Inn - Adults Only
The Reach Key West, Curio Collection by Hilton
The Reach Key West, Curio Collection by Hilton
4 out of 5
1435 Simonton Street, Key West, FL
The price is ￥38,104 per night from Jun 29 to Jun 30
￥38,104
￥51,510 total
Jun 29 - Jun 30
includes taxes & fees
Stay at this 4-star beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.2/10 Very Good! (987 reviews)
"Great"

Reviewed on Jun 13, 2025

The Reach Key West, Curio Collection by Hilton
Orchid Key Inn - Adults Only
Orchid Key Inn - Adults Only
3.5 out of 5
1004 Duval St, Key West, FL
Stay at this 3.5-star hotel in Key West. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
9.8/10 Exceptional! (1,003 reviews)
"Absolutely love this small boutique hotel . Love the staff, location, amenities, cleanliness and the craft cocktails . This property really pays attention to the little things like a microwave in the room , sun blocking lotions ( in case you forgot yours) . The soap, shampoo/conditioner , lotions ..."

Reviewed on Jun 11, 2025

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Orchid Key Inn - Adults Only
Southwinds Motel
Southwinds Motel
2 out of 5
1321 Simonton Street, Key West, FL
The price is ￥19,156 per night from Jun 16 to Jun 17
￥19,156
￥25,603 total
Jun 16 - Jun 17
includes taxes & fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,102 reviews)
"It is not fancy, but the price was right. A block from Duval. Rent a bike and you will rule! Pool was cleanand well maintained. Pretty 420 friendly. At least no one bothered me about smoking on the property."

Reviewed on Jun 14, 2025

Southwinds Motel
The Mansion on the Sea - Southernmost House in the USA
The Mansion on the Sea - Southernmost House in the USA
4 out of 5
1400 Duval Street, Key West, FL
The price is ￥32,992 per night from Jul 6 to Jul 7
￥32,992
￥37,116 total
Jul 6 - Jul 7
includes taxes & fees
Stay at this 4-star beach hotel in Key West. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff and the property condition ...
9.2/10 Wonderful! (1,000 reviews)
"The history in the house is rich. Even though it’s on the end of Dual it was quiet and we did not have a bunch of noise when trying to sleep or seep in. Breakfast in the morning was great."

Reviewed on Jun 5, 2025

The Mansion on the Sea - Southernmost House in the USA
See all 2,814 properties in Uptown - Upper Duval
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Uptown - Upper Duval

Key West Historic District

Old Town Key West

Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.

Old Town Key West
Key West featuring a marina, a coastal town and general coastal views

Downtown Key West

If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.

Downtown Key West
Harry S. Truman Little White House which includes a house and cycling

Bahama Village

Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.

Bahama Village
Clarence S. Higgs Memorial Beach Park which includes landscape views, tropical scenes and a sandy beach

Casa Marina

While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.

Casa Marina
Audubon House and Tropical Gardens featuring a house

Key West Historic District

Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.

Key West Historic District
Great location for great pictures, very nice beach

White Street Gallery District

When in White Street Gallery District, you can plan a visit to Duval Street and Saint Mary Star of the Sea, some noteworthy sights in the nearby area.

White Street Gallery District

Uptown - Upper Duval, FL