Eastern Sicily Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • Better together

    Save up to ￥45,448 when you book a flight and hotel together*

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

    Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Eastern Sicily

Find the best Eastern Sicily areas and neighborhoods for the activities you enjoy most. Learn more about Eastern Sicily
Temple of Apollo featuring a ruin and heritage elements

Ortigia

4.5/5(147 area reviews)

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

Find hotels in Ortigia

Find the Best Eastern Sicily Vacation Packages

Eastern Sicily Hotel Deals

UNA Hotels Capotaormina

UNA Hotels Capotaormina

4 out of 5
Via Nazionale, 105, Taormina, ME
The price is ￥40,726 per night from Oct 31 to Nov 1
￥40,726
￥46,204 total
Oct 31 - Nov 1
includes taxes & fees
9.2/10 Wonderful! (1,001 reviews)
"Fabulous pool and private beach!"

Reviewed on Oct 4, 2025

UNA Hotels Capotaormina
Palace Catania | UNA Esperienze

Palace Catania | UNA Esperienze

4 out of 5
Via Etnea 218, Catania, CT
The price is ￥28,268 per night from Nov 10 to Nov 11
￥28,268
￥31,972 total
Nov 10 - Nov 11
includes taxes & fees
9.2/10 Wonderful! (1,003 reviews)
"We loved everything about this hotel. The desk set us up with a driver Francesco, who was amazing!!! The room was spacious, very clean and the staff was friendly. The roof top restaurant was a big plus"

Reviewed on Oct 9, 2025

Palace Catania | UNA Esperienze
Romano Palace Luxury Hotel

Romano Palace Luxury Hotel

5 out of 5
Viale Kennedy 28, Catania, CT
Fully refundableReserve now, pay when you stay
The price is ￥16,154 per night from Nov 2 to Nov 3
￥16,154
￥19,527 total
Nov 2 - Nov 3
includes taxes & fees
7.8/10 Good! (894 reviews)
"We really enjoyed the great atmosphere around the pool in the afternoon and also having a delicious dinner outside in the garden"

Reviewed on Oct 4, 2025

Romano Palace Luxury Hotel
See all 13,759 properties in Eastern Sicily
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Eastern Sicily

Mount Etna

Mount Etna

This tranquil city is in a stupendous position on the sea in front of Mount Etna, with a mild climate year round and marvellous scenery, where peace and quiet reign supreme. It's been world famous for centuries, which has brought an influx of noteworthy tourists, even today, thanks to the numerous holiday promotions for Taormina.

Mount Etna
Taormina Cable Car

Taormina Cable Car

On this quick and practical lift system, appreciate the picturesque views as you soar above the beaches and coves of Mazzarò and spot the historic landmarks of Taormina.

Taormina Cable Car
Greek Theatre showing building ruins and heritage architecture

Greek Theatre

Visit this ancient theater to admire Roman ruins, watch internationally acclaimed musicians and enjoy stunning views across the Bay of Nexus.

Greek Theatre

What to do in Eastern Sicily

Archaeological Park of Selinunte, The Temple of Era

Selinunte Archaeological Park and Cusa Caves from Palermo, Private Tour

￥95,602
per adult
Selinunte Archaeological Park and Cusa Caves from Palermo, Private Tour
See all activities in Eastern Sicily

Frequently asked questions

Can I cancel my flight booking to Eastern Sicily due to COVID-19?
If you've yet to book your tickets, read the terms and conditions of the airfare you're considering. If you've already secured your flight to Eastern Sicily, click through to our Customer Service Portal. The information here will help you figure out which COVID-19 policies apply to your booking and guide you with the next steps.
What's the best way to find cheap flights to Eastern Sicily that have flexible change policies?
At Expedia, we've been channeling our inner acrobat to deliver you the most flexible fares available. Simply check the "No change fee" box directly under the "Flexible change policies" heading to find your perfect flight to Eastern Sicily.
What are some of the general tips for travelers to Eastern Sicily during the COVID-19 outbreak?
COVID-19 has affected how the world works in a profound way, including how we're able to safely travel. These tips will help you better understand these new challenges and get you ready for your trip to Eastern Sicily:
  • Find out if any travel restrictions apply to your destination and origin before committing to a flight. Also check if there are any special conditions you'll have to follow on arrival, such as taking a COVID-19 test.
  • Keep your face mask on during airport screening. A TSA employee will require you to temporarily lower your mask to verify your identity.
  • Instead of handing a TSA officer your boarding pass, place it directly on the reader yourself. After that, hold it up for inspection.
  • TSA is now permitting passengers to take one container of hand sanitizer, up to 12 oz (350 ml) in size, in carry-on luggage. This will have to be removed from your bag for scanning.
  • Put any personal items (like your phone and wallet) in your carry-on rather than a bin to reduce handling during the screening process.
  • Separate any food you're carrying for screening. Food items often trigger the alarm. Putting them in a clear plastic bag and into a bin reduces the need for a TSA agent to touch and inspect your belongings.

Which airlines fly to Eastern Sicily?
Alitalia is a leading airline servicing Eastern Sicily. Search for a ticket to Fiumicino - Leonardo da Vinci Intl. Airport (FCO) and you'll have 4332 Alitalia flights per month to select from.
How can I find cheap tickets to Eastern Sicily?
A great strategy for scoring cheap airfares is to be flexible with your travel dates. Begin with searching for your flight to Eastern Sicily, then click on the "flexible dates" box to compare prices for nearby days. Another helpful hint? Book well in advance. To give you an idea of fares, was the best price for a flight to Eastern Sicily in the last seven days.
How much is a flight to Eastern Sicily?
The price of a round-trip airfare to Eastern Sicily in the last seven days fluctuated between and . If you were journeying one way from (), you could have nabbed a deal from only .
What are the most popular airports to fly into in Eastern Sicily?
Fiumicino - Leonardo da Vinci Intl. Airport (FCO) is the main entry point for many traveling to Eastern Sicily. Approximately 9664 monthly flights touch down at this airport.
When is the cheapest time to fly to Eastern Sicily?
Departing on a Tuesday, followed by a Monday, is usually the best way to secure the cheapest flight. Steer clear of weekends if possible, because Saturday is typically the most expensive day. Spend the money you saved having a blast in Eastern Sicily instead!
How much is a plane ticket to Eastern Sicily?
Plane fares ranged anywhere from to over the last seven days. When you're ready to book, we're ready to help you land the best deal to Eastern Sicily.
Which airlines with flights to Eastern Sicily employ COVID-19 cleanliness policies?
As travel bans start to lift, many airlines are back in the skies with new measures including physical distancing and enhanced disinfection measures. Here's what these carriers are doing to help stop the spread of COVID-19:
  • Alitalia - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Vueling - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Ryanair - this airline is known for cleaning with disinfectant and providing passenger masks.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.