East Prairie Vacations

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    Plan, book, and manage your trip all in one place

Find the Best East Prairie Vacation Packages

East Prairie Hotel Deals

Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is ￥12,856 per night from Jul 20 to Jul 21
￥12,856
￥14,654 total
Jul 20 - Jul 21
includes taxes & fees
8.2/10 Very Good! (1,000 reviews)
"The front desk was amazing! Recommended great places to visit and did laundry onsite during our stay also. The check in and out was very easy and they made our stay very welcoming and comfortable. Everything was very clean, I would just be mindful at checking the sheets / brief stains on pillow cases ..."

Reviewed on Jun 18, 2025

Best Western Plus Sikeston
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is ￥13,147 per night from Jun 29 to Jun 30
￥13,147
￥15,115 total
Jun 29 - Jun 30
includes taxes & fees
9.4/10 Exceptional! (1,001 reviews)
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Reviewed on Jun 19, 2025

Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is ￥11,782 per night from Jul 20 to Jul 21
￥11,782
￥13,427 total
Jul 20 - Jul 21
includes taxes & fees
7.2/10 Good! (1,002 reviews)
"This property is updated, fresh paint in the halls and alot of work has gone into this location. The bed is comfortable and there are plenty of pillows (4)."

Reviewed on Jun 21, 2025

Days Inn and Suites by Wyndham Sikeston
See all 81 properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an East Prairie vacation package cost?
Offering excellent value package deals on Expedia, you'll be thrilled with how little a vacation to East Prairie costs! Our packages mean less travel planning for you and greater savings.
What are the cheapest months to go to East Prairie?
If you're hoping to book a cheap East Prairie vacation package, consider traveling in January, February and November. You'll generally find lower prices on flights and accommodations during these months --- ideal for a budget-friendly getaway.
How many days is enough for East Prairie?
With a well-organized schedule, you can easily tick off the most popular East Prairie attractions in a few days. But if you prefer to discover lesser-known spots or go on day tours, think about booking your East Prairie vacation for longer.
How to find the best East Prairie package deals?
Landing a cheap East Prairie package deal is easy with Expedia. Once you've entered your destination and trip dates under our "Packages" tab, set your budget range, add a few filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Sort the results by "Price: low to high" to view the most wallet-friendly East Prairie package deals. Want a simple trick to get even more savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are typically lower.
Is it cheaper to book an East Prairie vacation as a package?
An Expedia vacation package could score you significant savings when compared to booking hotels and flights individually. Better still, you can tailor your East Prairie trip to fit your exact style. Pick your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to East Prairie?
Enjoy amazing discounts by booking your flights ahead of time with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment East Prairie getaway.
How to plan a trip to East Prairie?

  1. Choose the perfect time to travel: Your schedule, preferred season and the type of weather you enjoy can all impact your decision on when to go to East Prairie.
  2. Budget wisely: Besides the price of your accommodations, you'll need to consider other expenses too. These include transportation, food and flights. Also, put aside some extra funds for unexpected expenses that may crop up during your trip to East Prairie.
  3. Decide how many days away: Start by compiling a list of the activities and attractions you want to experience in East Prairie. Then, estimate how long you'll need for each, along with any travel time.
  4. Combine your flights and hotel: Awesome destination, check. Length of stay, check. All that's left now is to pick an East Prairie vacation package that brings all your bookings together.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.