East Prairie Vacation Rentals

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Check prices for these dates

Tonight
Dec 23 - Dec 24
Tomorrow
Dec 24 - Dec 25
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Our top choices for East Prairie vacation rentals

TV, DVD player
Charming 3-bedroom house near ball park in quiet neighborhood

Charming 3-bedroom house near ball park in quiet neighborhood

Charming 3-bedroom house near ball park in quiet neighborhood
Bardwell
10.0 out of 10, Exceptional, (12)
"Quaint stay to see Grand and kids. "
United States
Sheila C.
The price is ￥14,121
￥25,197 total
includes taxes & fees
Dec 30 - Dec 31
Charming 3-bedroom house near ball park in quiet neighborhood
Smart TV
Tranquil charming Tiny House in Clinton

Tranquil charming Tiny House in Clinton

Tranquil charming Tiny House in Clinton
2.0 star property
Clinton
The price is ￥15,690
￥25,197 total
includes taxes & fees
Dec 24 - Dec 25
Tranquil charming Tiny House in Clinton
Exterior
The Hut. Cozy 2-bedroom mobile home on peaceful Reelfoot Lake with boat shed

The Hut. Cozy 2-bedroom mobile home on peaceful Reelfoot Lake with boat shed

The Hut. Cozy 2-bedroom mobile home on peaceful Reelfoot Lake with boat shed
2.0 star property
Hornbeak
9.8 out of 10, Exceptional, (48)
"It was peaceful and Beautiful!"
United States
Jimmie W.
The price is ￥25,889
￥45,757 total
includes taxes & fees
Dec 24 - Dec 25
The Hut. Cozy 2-bedroom mobile home on peaceful Reelfoot Lake with boat shed
Interior
3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
2.0 star property
Hornbeak
10.0 out of 10, Exceptional, (1)
"The house was exaclty what we needed. It had everything we needed. We will be back. Great set up for a large group. "
United States
Jon R.
The price is ￥31,380
￥60,289 total
includes taxes & fees
Dec 24 - Dec 25
3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
Terrace/patio
Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR

Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR

Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR
Hornbeak
9.8 out of 10, Exceptional, (56)
"Nice place, has everything you need."
United States
Joe V.
The price is ￥26,124
￥45,603 total
includes taxes & fees
Dec 24 - Dec 25
Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR
Fridge, microwave, oven, stovetop
Charming 3-bedroom house with WiFi, AC in amazing Hornbeak

Charming 3-bedroom house with WiFi, AC in amazing Hornbeak

Charming 3-bedroom house with WiFi, AC in amazing Hornbeak
Hornbeak
10.0 out of 10, Exceptional, (5)
"It was enjoyable and loved the house."
United States
Paula F.
The price is ￥24,712
￥43,683 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Charming 3-bedroom house with WiFi, AC in amazing Hornbeak
Exterior
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
New Madrid
10.0 out of 10, Exceptional, (1)
"The host was very quick to respond and so great to work with for on our stay. "
United States
Jessica S.
The price is ￥31,380
￥53,503 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
Smart TV
The Hut II on Reelfoot Lake

The Hut II on Reelfoot Lake

The Hut II on Reelfoot Lake
Hornbeak
10.0 out of 10, Exceptional, (1)
"We loved that the home is walking distance to the lake! We came in to hunt for a few days, and one of the reasons we chose this home was the number of beds it offered. It was fully equipped with everything we needed to make our stay comfortable. The host was incredibly welcoming and responsive, making our stay stress-free and enjoyable. We would absolutely stay here again!"
United States
Heather T.
The price is ￥25,889
￥45,757 total
includes taxes & fees
Dec 24 - Dec 25
The Hut II on Reelfoot Lake
Outdoor dining
Come and relax at the Refuge at beautiful Reelfoot Lake!

Come and relax at the Refuge at beautiful Reelfoot Lake!

Come and relax at the Refuge at beautiful Reelfoot Lake!
Hornbeak
9.4 out of 10, Exceptional, (23)
"Great place "
United States
William
The price is ￥22,594
￥40,645 total
includes taxes & fees
Dec 24 - Dec 25
Come and relax at the Refuge at beautiful Reelfoot Lake!
Outdoor dining
Vacation rental attached to our house out in the country.

Vacation rental attached to our house out in the country.

Vacation rental attached to our house out in the country.
Union City
The price is ￥15,690
￥25,448 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Vacation rental attached to our house out in the country.
Interior
Log Cabin.

Log Cabin.

Log Cabin.
Hornbeak
9.0 out of 10, Wonderful, (32)
"Nice place, would book again! "
United States
Lisette B.
The price is ￥38,441
￥79,441 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Log Cabin.
Fridge, microwave, oven, stovetop
Tiny house on the lake With a seventy five inch t v free internet walk shower

Tiny house on the lake With a seventy five inch t v free internet walk shower

Tiny house on the lake With a seventy five inch t v free internet walk shower
Tiptonville
The price is ￥21,182
￥39,031 total
includes taxes & fees
Dec 24 - Dec 25
Tiny house on the lake With a seventy five inch t v free internet walk shower
3 bedrooms, iron/ironing board, free WiFi, bed sheets
Sunkist beach house. Lake side house 3 bedroom house

Sunkist beach house. Lake side house 3 bedroom house

Sunkist beach house. Lake side house 3 bedroom house
Tiptonville
10.0 out of 10, Exceptional, (5)
"The house was nice and clean and had every thing on hand that we needed. The host was excellent to deal with. We would definitely stay here again. It’s in a nice quiet neighborhood and the kids enjoyed the park that’s right down the road. "
United States
Deanna P.
The price is ￥35,303
￥57,118 total
includes taxes & fees
Dec 24 - Dec 25
Sunkist beach house. Lake side house 3 bedroom house
Exterior
Guest house and spacious shop located between Discovery Park and Reelfoot Lake

Guest house and spacious shop located between Discovery Park and Reelfoot Lake

Guest house and spacious shop located between Discovery Park and Reelfoot Lake
Union City
10.0 out of 10, Exceptional, (3)
"Wonderful place to relax. Home has everything you need. The additional party barn is an added bonus!!"
United States
william P.
The price is ￥39,539
￥60,647 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Guest house and spacious shop located between Discovery Park and Reelfoot Lake
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top East Prairie Hotel Reviews

New Orleans Inn Portageville

New Orleans Inn Portageville

10/10 Excellent
"Friendly sta"
Melissa 2-night trip
Posted 3 days ago
New Orleans Inn Portageville

Find out more about East Prairie

Search for holiday rentals in East Prairie on Expedia! You can easily find your home rentals, villas, holiday apartments in East Prairie using one of the methods below:

  • View our selection of featured holiday rentals in East Prairie
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  • Enter your travel dates to view the best deals on holiday rentals in East Prairie while they last

Look no further and take a look at our great range of rental properties in East Prairie!

Frequently asked questions

Can I find a vacation rental in East Prairie?

Yes, you can find vacation rentals near the most popular sights in East Prairie, or you can select a more secluded option if you're looking for a relaxing stay.

What's the top vacation rental that East Prairie has to offer?

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters: This vacation home rental near East Prairie is located on a lake and has a fireplace, a patio, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop.

What can I see and do in East Prairie?

Mississippi River and Big Oak Tree State Park are a couple of lovely local spots to get outside and enjoy nature. In the larger area, you’ll find Central Park and Sikeston Depot Museum.

What are vacation rentals like in East Prairie?

Vacation rentals are privately owned accommodations you can reserve for a few days or a quick weekend in East Prairie. Vacation rentals feature extras like kitchens and laundry facilities so you'll feel right at home. If you're concerned about a sanitized environment, vacation rentals can offer a sense of security away from public hotel elevators and lobbies packed with people while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a popular choice for family trips.