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Compare 1,566 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.
Our top choices for Colon hotels

Hotel Marparaiso
Hotel Marparaiso

The Westin Panama
The Westin Panama

Courtyard by Marriott Panama Metromall
Courtyard by Marriott Panama Metromall

La Cubana Hotel & Residencial
La Cubana Hotel & Residencial

Hotel Sotelo
Hotel Sotelo

SAND DIAMOND HOTEL
SAND DIAMOND HOTEL
Check out hotels with free breakfast in Colon

Gamboa Rainforest Reserve
Gamboa Rainforest Reserve
Hotels with a pool in Colon you'll enjoy

Gamboa Rainforest Reserve
Gamboa Rainforest Reserve
These pet-friendly hotels in Colon may fit your trip

Marina Hotel at Shelter Bay
Marina Hotel at Shelter Bay
Where to stay in Colon

Cristobal
This historic port neighborhood offers a fascinating glimpse into Panama's maritime heritage at the Caribbean entrance to the Panama Canal. Watch massive ships navigate the impressive Gatun Locks while strolling along the waterfront promenade. Colonial architecture tells the story of American canal construction throughout Cristobal. The Colon Free Zone beckons shoppers with duty-free electronics and designer goods just minutes away. Local eateries serve Caribbean-influenced Panamanian seafood dishes that reflect the area's diverse cultural influences. Though primarily a working port, Cristobal rewards visitors with authentic maritime experiences and sweeping harbor views.
Barrio Sur
Barrio Sur reveals Panama's Afro-Caribbean soul through weathered colonial buildings painted in faded pastels. Caribbean wooden balconies overlook narrow cobblestone streets where the aroma of fried plantains fills the air. West Indian influences shine through local customs, architecture, and the rhythms of reggae and calypso. This historic district offers glimpses into Colón's significance during the Panama Canal construction era. Budget-friendly guesthouses and family-run eateries serving authentic rice and beans make exploration affordable. The neighborhood's compact layout means most attractions are just a short walk away.
Barrio Norte
Experience the rich Afro-Caribbean heritage of Barrio Norte in Colón. This authentic cultural enclave offers a genuine glimpse into everyday Panamanian life with its colorful concrete houses and lively community atmosphere. Travelers can observe locals chatting on porches and hear Caribbean music drifting through narrow streets. Budget-conscious visitors will appreciate the affordable family-run guesthouses and traditional comedores serving flavorful Caribbean-influenced dishes. While tourist infrastructure is minimal, the neighborhood provides easy access to Limon Bay and Monument to Christopher Columbus. The close-knit community welcomes respectful travelers seeking authentic cultural exchange beyond Panama City's tourist zones.
Stay near popular Colon attractions

Gamboa Rainforest Resort
Explore the great outdoors at Gamboa Rainforest Resort, a lovely green space in Gamboa. While you're here, you can savor the top-notch restaurants.
Learn more about Colon
Explore the colorful Zona Libre free trade zone for duty-free shopping and visit the historic Colon 2000 cruise port. Discover Panama's colonial history at Fort San Lorenzo, located on the Caribbean coast outside the city.

More cheap stays in Colon
More cheap stays in Colon

Arcadia Condo Suites
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels in Colon Neighborhoods
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