Colon Vacation Rentals

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Our top choices for Colon vacation rentals

Aparthotel in Costa del Este

Arcadia Condo Suites
2.5 star property
9.4 out of 10, Exceptional, (177)
"Was a great buy. Beautiful views and spacious rooms. Great amenities. "
United States
Lesley
The price is ¥12,914
¥21,411 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Arcadia Condo Suites

Apartment in San Francisco

San Francisco by Wynwood House
3.0 star property
9.2 out of 10, Wonderful, (56)
"Clean and walkable location"
United States
Tamera
The price is ¥18,810
¥24,590 total
includes taxes & fees
Jan 19 - Jan 20, 2026
San Francisco by Wynwood House

Apartment in Bella Vista

Boutique Apartments Panama
3.5 star property
7.6 out of 10, Good, (224)
"The view was amazing and the place was great could stay here again "
United States
Yonnette
Boutique Apartments Panama

Aparthotel in Casco Viejo

Las Clementinas
3.5 star property
9.4 out of 10, Exceptional, (172)
"Fabulous room and wonderful people that work there. "
Canada
Leah
The price is ¥21,674
¥23,841 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Las Clementinas

Aparthotel in Casco Viejo

La Isabela Suites
3.5 star property
10.0 out of 10, Exceptional, (171)
"Wonderful charming property in the heart of the historic district. "
United States
Angela
La Isabela Suites

Apartment in Bella Vista

Yoo Panamá by Boutique Apartments
3.5 star property
8.2 out of 10, Very Good, (50)
"The hotel as well as the room exceeded our expectations. I would recommend staying at the Yoo via expedia. Thanks again... Reggie"
United States
Reginald
The price is ¥10,094
¥32,783 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Yoo Panamá by Boutique Apartments

Apartment in Amador

La Palma Aparta Suite
3.0 star property
The price is ¥7,393
¥12,811 total
includes taxes & fees
Jan 6 - Jan 7, 2026
La Palma Aparta Suite
2.0 star property
The price is ¥11,934
¥14,963 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Swette Love 10 Minutes From the Airport Tocumen

Apartment in San Francisco

Boutique Apartments Atlapa
3.0 star property
8.0 out of 10, Very Good, (28)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
United States
Shamia
Boutique Apartments Atlapa

Apartment in Bella Vista

Yoo Panama & Arts Tower
3.0 star property
9.6 out of 10, Exceptional, (57)
"Ron was amazing and so was the property!"
United States
John
Yoo Panama & Arts Tower

Apartment in Veracruz

Centriqo by Wynwood house
3.0 star property
The price is ¥19,933
¥27,073 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Centriqo by Wynwood house

Apartment in Casco Viejo

Casa Contemporanea by Wynwood House
4.0 star property
8.2 out of 10, Very Good, (20)
"Great place!"
United States
Jad
The price is ¥18,248
¥23,972 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Casa Contemporanea by Wynwood House

Aparthotel in Bella Vista

Torres de Alba Hotel & Suites
3.5 star property
8.8 out of 10, Excellent, (486)
"Room was clean, neat great staff"
United States
Alfredo
Torres de Alba Hotel & Suites

Apartment in San Francisco

Wanders Panama by Boutique Apartments
4.0 star property
10.0 out of 10, Exceptional, (2)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is ¥30,799
¥57,727 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Wanders Panama by Boutique Apartments
3.0 star property
The price is ¥3,679
¥5,705 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Habitación Privada en Playa Dorada + Kitchenette

Condo in Calidonia

Yoo by Wynwood House
4.0 star property
9.2 out of 10, Wonderful, (5)
"I will be back!"
United States
Jeffrey
The price is ¥24,164
¥32,070 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Yoo by Wynwood House

Apartment in Casco Viejo

Casa Lefevre By Wynwood House
3.5 star property
8.8 out of 10, Excellent, (3)
"Once I remembered the email about access to the hotel it was all great from then on. A great surprise when I opened the door and saw this huge open space room. I loved it. "
United States
Jeff
The price is ¥18,529
¥24,671 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Casa Lefevre By Wynwood House
2.0 star property
The price is ¥11,237
¥12,361 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Charming 3 Bedroom Apartment in San Miguelito, Panama City

Apartment in San Francisco

Dovle 512 in Ciudad de Panam
2.0 star property
The price is ¥39,141
¥43,055 total
includes taxes & fees
Jan 22 - Jan 23, 2026
Dovle 512 in Ciudad de Panam

Aparthotel in Calidonia

Edificio Doña Raquel
2.0 star property
The price is ¥40,717
¥55,811 total
includes taxes & fees
Jan 29 - Jan 30, 2026
Edificio Doña Raquel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Colon Hotel Reviews

Find out more about Colon

Search for holiday rentals in Colon on Expedia! You can easily find your home rentals, villas, holiday apartments in Colon using one of the methods below:

  • View our selection of featured holiday rentals in Colon
  • Use the map to find apartments and other holiday homes in the Colon neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Colon while they last

Look no further and take a look at our great range of rental properties in Colon!

Frequently asked questions

Can I find a vacation rental in Colon?

Yes, we give you a choice of vacation rentals close to top local attractions in Colon, or you can go with a secluded option if you want a relaxing place to stay. Discover why Colon is known for its shops and lakeside.

What are some of the best vacation rentals that Colon has to offer?

Oasis with pool near panama canal: This vacation home rental outside of Colon offers an outdoor pool, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the garden in this rental home to help you unwind.

How many vacation rentals are there in Colon?

With 3 Expedia vacation rentals, you're sure to find just the right place for your Colon stay.

What’s there to see and do in Colon?

Gamboa Rainforest Resort and Limon Bay are a couple of scenic spots to enjoy the outdoors, whereas Colón Art and Culture Center is one of the cultural attractions. Colon 2000 and Colon Free Zone are other places to visit while you're in town.

What’s a vacation rental in Colon like?

Vacation rentals are privately owned properties you can stay in for a couple of days or more in Colon. Vacation rentals feature extras like WiFi and washers and dryers so you'll have everything you want. If you're concerned about a sanitized environment, vacation rentals can offer a sense of privacy away from public hotel elevators and busy reception areas while still allowing you the enjoyment of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive choice for a small group gathering.