A historic stone fortress with a central dome and surrounding walls.

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Check availability on Colon Luxury Hotels

This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Our top choices for Colon luxury hotels

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.

1. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (6,143 reviews)
  • cleanliness
    Exclusive Panama City escape offers lavish poolside retreats and gourmet dining experiences.
The price is ￥18,771
￥20,648 total
includes taxes & fees
Nov 25 - Nov 26
Hotel Riu Plaza Panama
A balcony with a table, chairs, and a view of a city skyline across a body of water.

2. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (769 reviews)
  • cleanliness
    Indulge in colonial elegance at this Panama City gem featuring a full-service spa, outdoor pool, and gourmet dining.
The price is ￥66,618
￥73,280 total
includes taxes & fees
Nov 1 - Nov 2
Sofitel Legend Casco Viejo, Panama City
A poolside area with lounge chairs and a view of the ocean.

3. JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.2 out of 10, Wonderful, (1,003 reviews)
  • cleanliness
    Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
The price is ￥46,491
￥51,140 total
includes taxes & fees
Nov 27 - Nov 28
JW Marriott Panama
A hotel courtyard with a central lawn, surrounded by buildings with balconies and outdoor seating areas.

4. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (370 reviews)
  • cleanliness
    Experience historic luxury in Panama's Casco Viejo district with 5 restaurants and a rooftop pool with spectacular views.
The price is ￥46,854
￥51,539 total
includes taxes & fees
Oct 29 - Oct 30
Hotel La Compañía Casco Antiguo
A hotel entrance with a central water feature, seating areas, and potted plants.

5. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (768 reviews)
  • cleanliness
    Elevate your Panama City escape with a Jack Nicklaus golf course, rejuvenating spa treatments, and poolside luxury at this 5-star retreat.
The price is ￥49,189
￥54,108 total
includes taxes & fees
Nov 22 - Nov 23
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.

6. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.6 out of 10, Excellent, (1,829 reviews)
  • cleanliness
    Experience luxury and elegance in a Panamanian retreat with 2 restaurants, a spa, and casino.
The price is ￥25,158
￥27,674 total
includes taxes & fees
Oct 31 - Nov 1
Megapolis Hotel Panamá
A modern building with a rooftop lounge area, large windows, and a balcony overlooking a cityscape.

7. Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,002 reviews)
  • cleanliness
    Panama City elegance at this Waldorf Astoria hotel with a full-service spa, outdoor pool, and refined dining in two upscale restaurants.
The price is ￥42,703
￥46,973 total
includes taxes & fees
Nov 14 - Nov 15
Waldorf Astoria Panama
A modern hotel pool area with lounge chairs and a clear view of the ocean.

8. Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Panama City sophistication meets relaxation with an attached winery, poolside dining, and a full-service spa offering couples' treatments.
The price is ￥41,365
￥45,501 total
includes taxes & fees
Nov 20 - Nov 21
Hilton Panama
A high-rise building with a rooftop pool area, surrounded by other buildings.

9. W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,004 reviews)
  • cleanliness
    Lavish urban retreat offers 3 hot tubs, poolside luxury, and concierge services in Panama city.
The price is ￥45,231
￥49,754 total
includes taxes & fees
Nov 21 - Nov 22
W Panama
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.

10. Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Bella Vista
9.6 out of 10, Exceptional, (492 reviews)
  • cleanliness
    Indulgence awaits in this 4.5-star Panama City sanctuary featuring a full-service spa, outdoor pool, and elegant dining near Via Espana.
The price is ￥34,963
￥38,459 total
includes taxes & fees
Nov 12 - Nov 13
Hyatt Regency Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Colon Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"You staff was on top of everything thing that we needed . Very helpful in directing us to the right people and tours. They even recognize my birthday. They sent up birthday cake and a fruit basket. I was very impressed. Thanks to your lovely staff ."
Marlene 2-night trip
Posted 1 hour ago
Hotel Riu Plaza Panama

Frequently asked questions

Are you looking for a luxury hotel for your Colon vacation?
Use Expedia to arrange your flight to Panama City (PAC-Marcos A. Gelabert Intl.) airport or Balboa (BLB-Panama Pacifico Intl.) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Colon offers. Colon has some interesting things to see and do including Colon 2000 and Colon Free Zone, so you might want to take in the local sights during your visit.
What's the best high-end hotel in Colon?
Sand Diamond Hotel is a luxury hotel with ski-in/ski-out access and a casino, and it's a popular choice for Expedia travelers looking for an elegant place to stay.
When can I expect good weather in Colon?
Planning for the weather is an important factor for making your trip to Colon a success, especially when you're splurging. The hottest months are usually May and September with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in Colon are November, July, August, and October, with each month seeing an average of 14 inches of rainfall.
What's there to see and do in Colon?
Take in the sights and attractions that Colon offers with a visit to Colon 2000, Colon Free Zone, and Gamboa Rainforest Resort. If you have extra time while you're in the area, you might want to see Fantastic Casino | Colón 2000 and Fort San Lorenzo.
How can I get around Colon?
It's easier to get around town in style when you know your options. To see more of the larger area, ride aboard one of the trains from Colon Atlantic Passenger Station.