Central Iowa, IA Vacation Homes from ￥11,125

Central Iowa Vacation Homes
United States of America
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A historic building with a large central archway and a pond in the foreground.

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Our top choices for Central Iowa vacation homes

A modern kitchen with wooden cabinets, a central island with bar stools, a microwave, and a stove.

A bedroom with a bed, nightstand, lamp, ceiling fan, window, and a mirror.

A modern living room with a leather sofa, a flat-screen TV mounted above a stone fireplace, and a hallway leading to another room.

A modern living room with a sectional sofa, a marble coffee table, and a kitchen in the background.

1. Sleeps 6, 3BR-3BA | Easy I-35 Access

Sleeps 6, 3BR-3BA | Easy I-35 Access

Huxley

10.0 out of 10, Exceptional, (2 reviews)

10/10

Exceptional

(2 reviews)

"We enjoyed our stay. Perfect for visiting our ISU student."

Mary Jo T.

The price is ￥18,871

￥18,871

￥38,644 total

includes taxes & fees

Oct 12 - Oct 13

Sleeps 6, 3BR-3BA | Easy I-35 Access

A living room with a fireplace, a sofa set, a coffee table, and a door with a stained glass design.

A dining area with a wooden table and chairs, a chandelier, and a staircase with a wooden handrail.

A living room with a fireplace, sofa, and coffee table.

A kitchen with wooden cabinets, a stove, a sink, and a refrigerator.

2. 3BR-2BA, Sleeps 8 | Close to I-35

3BR-2BA, Sleeps 8 | Close to I-35

Ames

10.0 out of 10, Exceptional, (1 review)

10/10

Exceptional

(1 review)

"Loved the place and layout was perfect for us. Was an abundance of ants and spiders inside but other than that no problems."

Will M.

The price is ￥23,588

￥23,588

￥46,100 total

includes taxes & fees

Oct 12 - Oct 13

3BR-2BA, Sleeps 8 | Close to I-35

A backyard with a wooden deck, a picnic table, and a small shed.

A bedroom with a bed, curtains, a TV, and a view of the outdoors.

A single-story house with a sloped roof, surrounded by a well-maintained lawn and trees.

A playground with a slide, climbing structures, and a bridge.

3. Sleeps 10 - 5BR - Minutes to Campus - Next to Park, Golf, Shopping

Sleeps 10 - 5BR - Minutes to Campus - Next to Park, Golf, Shopping

Ames

10.0 out of 10, Exceptional, (4 reviews)

10/10

Exceptional

(4 reviews)

"Very family friendly- lots of room for all of us and the park across the street was great. Easy access and very quiet neighborhood. Neat clean home."

Melanie K.

The price is ￥42,744

￥42,744

￥84,576 total

includes taxes & fees

Oct 11 - Oct 12

Sleeps 10 - 5BR - Minutes to Campus - Next to Park, Golf, Shopping

A dining area with a wooden table, chairs, and a decorative mirror. There are white paneled walls and a ceiling light fixture.

A modern kitchen with a double sink, white cabinets, and a view to a dining area.

A spacious living room with a large flat-screen TV, a black dresser with gold knobs, a green sofa, and a wooden coffee table.

A spacious living area with a staircase, a green sofa, a white armchair, a coffee table, and a floor lamp.

4. 3BR Getaway, Sleeps 6 | 2-3 Miles to ISU

3BR Getaway, Sleeps 6 | 2-3 Miles to ISU

Ames

9.6 out of 10, Exceptional, (23 reviews)

9.6/10

Exceptional

(23 reviews)

"Great stay at an economic price!"

Cory M.

The price is ￥18,790

￥18,790

￥39,968 total

includes taxes & fees

Oct 21 - Oct 22

3BR Getaway, Sleeps 6 | 2-3 Miles to ISU

A hallway with a wooden bench, a 'Guest Book,' and a 'Happy Home' sign.

A living room with a sofa, a coffee table, a TV, a floor lamp, and a ceiling fan.

A dining area with a table, chairs, and a ceiling fan.

A bedroom with a bed, a ceiling fan, a nightstand, a clock, and a window with curtains.

5. Cozy 2-bedroom house in peaceful Colo with AC

Cozy 2-bedroom house in peaceful Colo with AC

Colo

8.0 out of 10, Very good, (2 reviews)

8.0/10

Very good

(2 reviews)

"Stay was great"

Cory S.

The price is ￥21,372

￥21,372

￥44,382 total

includes taxes & fees

Oct 12 - Oct 13

Cozy 2-bedroom house in peaceful Colo with AC

A spacious living room with hardwood floors, a chandelier, a dining table with chairs, and a sofa.

A neatly made bed with a white duvet, multiple pillows, a bedside lamp, and a bedside table with a vase.

A room with a large mirror leaning against a white door with glass panels, wooden flooring, a bed with floral pillows, and a wall decorated with framed pictures.

A laundry room with a washing machine and dryer, a sink, and a window with sheer curtains.

6. Natural Nesting Grounds - Boone, IA

Natural Nesting Grounds - Boone, IA

Boone

9.8 out of 10, Exceptional, (36 reviews)

9.8/10

Exceptional

(36 reviews)

"Beautiful property. Owner was VERY accommodating to this first time VBRO user."

Kelli A.

The price is ￥18,206

￥18,206

￥31,384 total

includes taxes & fees

Oct 11 - Oct 12

Natural Nesting Grounds - Boone, IA

A two-story house with a front porch, a garage, and a small shed.

A dining table set with plates, cups, and cutlery, a vase with flowers, and a window with curtains.

WINTER SPECIAL: Your Stay Pays You Back—15% OFF Seven Oaks! Ski & Snowboard

A wooden suspension bridge with chains and wooden planks, surrounded by trees and dry leaves.

7. 1800s Home, Train-Themed Decor, Walk to Downtown & Attractions, Exclusive Perks

1800s Home, Train-Themed Decor, Walk to Downtown & Attractions, Exclusive Perks

Boone

10.0 out of 10, Exceptional, (75 reviews)

10/10

Exceptional

(75 reviews)

"We had a very nice and relaxing stay. There were many thoughtful amenities that we were greatful for. Beds were comfortable, temperature was easy to regulate, kitchen well equipped."

Sarah W.

The price is ￥30,633

￥30,633

￥39,275 total

includes taxes & fees

Oct 12 - Oct 13

1800s Home, Train-Themed Decor, Walk to Downtown & Attractions, Exclusive Perks

A modern kitchen with a central island, a dining area, and a living room with a sofa and decorative pillows.

A wooden staircase with a railing leading to a porch area.

A modern kitchen with a central island, bar stools, stainless steel appliances, and pendant lighting.

A wooden staircase leading to a dining area with a table and chairs.

8. Enjoy a stylish experience at this centrally-located newly built home.

Enjoy a stylish experience at this centrally-located newly built home.

Ankeny

10.0 out of 10, Exceptional, (10 reviews)

10/10

Exceptional

(10 reviews)

"Newly furnished, clean, close to activities. Would stay again!"

Liz D.

The price is ￥20,659

￥20,659

￥48,495 total

includes taxes & fees

Oct 12 - Oct 13

Enjoy a stylish experience at this centrally-located newly built home.

A spacious living area with a modern kitchen, a dining area, and a large window providing natural light.

A bedroom with a bed, a chair, a ceiling fan, a TV, and a patterned wall.

A modern living room with a fireplace, a glass coffee table, and comfortable seating.

A modern kitchen with a central island, white cabinetry, and blue chairs.

9. Entire Home-Beautiful 4BR, 3.5BA Retreat in Ankeny, Iowa 2 King Beds, Fenced, AC

Entire Home-Beautiful 4BR, 3.5BA Retreat in Ankeny, Iowa 2 King Beds, Fenced, AC

Ankeny

9.6 out of 10, Exceptional, (28 reviews)

9.6/10

Exceptional

(28 reviews)

"My family and I had a wonderful day at this home. There was a lot to do for our little kids and plenty of space for us. The fenced in backyard was a huge plus and we stayed out there for hours. Any questions we had the host was able to respond to very quickly and was always helpful and kind."

Jonathan D.

The price is ￥22,084

￥22,084

￥53,637 total

includes taxes & fees

Oct 13 - Oct 14

Entire Home-Beautiful 4BR, 3.5BA Retreat in Ankeny, Iowa 2 King Beds, Fenced, AC

A living room with a flat-screen TV, a coffee table, a sofa, a ceiling fan, and a kitchen in the background.

A ping pong table in a room with a staircase, wooden cabinets, and framed artwork on the walls.

A modern kitchen with wooden cabinets, stainless steel appliances, and a grey countertop.

A ping pong table in a room with a carpeted floor, a staircase, and several framed pictures on the walls.

10. Ankeny 3BR Duplex, King Bed, Workspace & Game Room

Ankeny 3BR Duplex, King Bed, Workspace & Game Room

Ankeny

7.0 out of 10, Good, (4 reviews)

7.0/10

Good

(4 reviews)

"Our stay at this location was perfect for our plans. It was close to the trails in the downtown area with easy access to restaurants & bars. The house was easy to check into & clean. Communication with host was quick & responsive. We will definitely look into booking again."

Amy S.

The price is ￥13,931

￥13,931

￥55,320 total

includes taxes & fees

Oct 13 - Oct 14

Ankeny 3BR Duplex, King Bed, Workspace & Game Room

A kitchen with a window, a sink, and a stove.

A laundry area with two washing machines, a wicker basket, a table, a broom, and a rug.

A red door with a keypad lock, a black coat rack with hangers, a bench, and a patterned rug.

A hotel room with a bed, a television mounted on the wall displaying various channels, and a window with blinds.

11. Entire Bungalow with Fenced-In Yard! Sleeps 6 & Pet-Friendly, Central Des Moines

Entire Bungalow with Fenced-In Yard! Sleeps 6 & Pet-Friendly, Central Des Moines

Des Moines

10.0 out of 10, Exceptional, (36 reviews)

10/10

Exceptional

(36 reviews)

"Awesome place and host! Highly recommend"

Melissa H.

The price is ￥19,469

￥19,469

￥29,764 total

includes taxes & fees

Oct 11 - Oct 12

Entire Bungalow with Fenced-In Yard! Sleeps 6 & Pet-Friendly, Central Des Moines

A modern kitchen with white cabinets, a black countertop, and stainless steel appliances.

An outdoor patio with wicker furniture, a table, and a decorative lantern.

A modern living room with a sectional sofa, a coffee table, and a ceiling fan.

A dining area with a wooden table, chairs, a chandelier, and artwork on the walls.

12. Spacious 4-bedroom house in Ankeny. For family, friends and business travelers.

Spacious 4-bedroom house in Ankeny. For family, friends and business travelers.

Ankeny

10.0 out of 10, Exceptional, (7 reviews)

10/10

Exceptional

(7 reviews)

"We had a wonderful stay. Property was very clean and provided the perfect accommodations for our group."

Nick H.

The price is ￥18,446

￥18,446

￥65,874 total

includes taxes & fees

Oct 25 - Oct 26

Spacious 4-bedroom house in Ankeny. For family, friends and business travelers.

A modern kitchen with white cabinets, a stainless steel refrigerator, and a built-in oven. There is a dining area with a zebra-patterned rug and black chairs.

A modern kitchen with white cabinets, stainless steel appliances, and a central island with bar stools.

A modern kitchen with white cabinets, stainless steel appliances, and a central island with a sink.

A row of single-family homes with a well-maintained lawn and a fire hydrant in the foreground.

13. The Rehoboth- Iowa -Entire Home, 4BR- Deluxe & Elegant, Great Location near I-35

The Rehoboth- Iowa -Entire Home, 4BR- Deluxe & Elegant, Great Location near I-35

Ankeny

10.0 out of 10, Exceptional, (4 reviews)

10/10

Exceptional

(4 reviews)

"Great space for a team meeting and retreat! Close enough to everything in Ankeny we could zip into town and grab what we needed or for dinner and it was also far enough away that the neighborhood was quiet and peaceful for some walks!"

Amanda F.

The price is ￥22,084

￥22,084

￥113,389 total

includes taxes & fees

Oct 11 - Oct 12

The Rehoboth- Iowa -Entire Home, 4BR- Deluxe & Elegant, Great Location near I-35

A modern apartment with a kitchen, living area, and a dining space.

A modern living room with a sofa, armchair, and coffee table. There is a ceiling fan and a kitchen in the background.

A modern kitchen with white cabinets, a stainless steel refrigerator, a microwave, and a bar area with white bar stools.

A two-story house with a white exterior, a garage, and a covered porch.

14. New Spacious 4-bedroom house in charming Ankeny with WiFi, AC-Prime Location

New Spacious 4-bedroom house in charming Ankeny with WiFi, AC-Prime Location

Ankeny

9.8 out of 10, Exceptional, (39 reviews)

9.8/10

Exceptional

(39 reviews)

"The place was a perfect location and space for our needs. Would definitely stay again."

Bonnie H.

The price is ￥22,027

￥22,027

￥52,437 total

includes taxes & fees

Oct 19 - Oct 20

New Spacious 4-bedroom house in charming Ankeny with WiFi, AC-Prime Location

A compact kitchen with a stove, oven, and refrigerator, a dining table with chairs, and a potted plant.

A bedroom with a bed, a nightstand, a lamp, and a window.

A modern living room with two armchairs, a coffee table, a chandelier, a round mirror, and a door leading to another room.

A single-story house with a front porch, a small front yard, and a driveway.

15. Natural Nook - Boone, IA

Natural Nook - Boone, IA

Boone

9.0 out of 10, Wonderful, (2 reviews)

9.0/10

Wonderful

(2 reviews)

"The perfect place to stay for a little get away."

Michelle S.

The price is ￥18,206

￥18,206

￥31,384 total

includes taxes & fees

Oct 11 - Oct 12

Natural Nook - Boone, IA

A ping pong table with a net, two paddles, and a ball rack in a room with a hexagonal light fixture on the ceiling.

A laundry room with a Samsung washer and dryer, a wooden shelf with a sign, and a white door.

A modern kitchen with grey cabinets, a marble countertop, and a wood floor.

A backyard with a covered patio, a wooden bench, and a small table.

16. Huge Home, Gym, Game Room, Spa, BBQ, Near I-35

Huge Home, Gym, Game Room, Spa, BBQ, Near I-35

Ankeny

10.0 out of 10, Exceptional, (27 reviews)

10/10

Exceptional

(27 reviews)

"My family and I thoroughly enjoyed our stay! The pool and the game room were the perfect amenities we were looking for. Will absolutely be back soon!!"

Beth A.

The price is ￥33,245

￥33,245

￥70,662 total

includes taxes & fees

Oct 27 - Oct 28

Huge Home, Gym, Game Room, Spa, BBQ, Near I-35

A hot tub with blue lighting, surrounded by four windows with light fixtures above.

A bedroom with a bed, a bedside table with a lamp, a mirror, and a wardrobe.

A dining area with a dark wooden table and wicker chairs, a green leafy wall with a decorative sign, and a white wall in the background.

A modern living room with a wooden dining table, white armchairs, a fireplace, a flat-screen TV, and a chandelier.

17. Ankeny’s Best/Hot tub/Theatre Room/Game Room

Ankeny’s Best/Hot tub/Theatre Room/Game Room

Ankeny

10.0 out of 10, Exceptional, (7 reviews)

10/10

Exceptional

(7 reviews)

"Fantastic place with a great vibe! Was perfect for our 4th of July Getaway!"

Conor F.

The price is ￥34,385

￥34,385

￥76,454 total

includes taxes & fees

Oct 21 - Oct 22

Ankeny’s Best/Hot tub/Theatre Room/Game Room

A single-story house with a front yard, a mailbox, and a tree.

A wooden deck with a wicker chair and a hot tub.

A modern kitchen with dark cabinets, stainless steel appliances, and a dining area with a marble table and chairs.

A living room with a gray sectional sofa, a small ottoman, a gray armchair, and a wooden floor. There is a window with curtains, a door, and a small table with a lamp.

18. Farmhouse Oasis

Farmhouse Oasis

Dallas Center

10.0 out of 10, Exceptional, (31 reviews)

10/10

Exceptional

(31 reviews)

"The property was great and would stay again and recommend to family and friends if ciming into town."

Michael D.

The price is ￥15,293

￥15,293

￥27,693 total

includes taxes & fees

Oct 12 - Oct 13

Farmhouse Oasis

A kitchen with white cabinets, a stainless steel microwave, an oven, a dishwasher, and a window with blinds.

A single-story house with a red door and white siding, a garage, and a lawn in front.

A living room with a green sofa, a pink armchair, a colorful rug, a teal cabinet, and a television.

A white cabinet with folded towels and a framed sign that says "HOME is where your story begins."

19. Retro themed 2-bedroom house in Boone The Retro Rambler is pet friendly!

Retro themed 2-bedroom house in Boone The Retro Rambler is pet friendly!

Boone

10.0 out of 10, Exceptional, (15 reviews)

10/10

Exceptional

(15 reviews)

"Nice little place with a great back yard, 3 season porch and was easy to find. The check in and out was simple. "

Faith O.

The price is ￥39,475

￥39,475

￥70,739 total

includes taxes & fees

Oct 11 - Oct 12

Retro themed 2-bedroom house in Boone The Retro Rambler is pet friendly!

A modern kitchen with white cabinets, granite countertops, a microwave, stove, and a dishwasher.

A black door with a colorful welcome mat and a wreath.

A hallway with a wooden floor, a white bench with a mirror, and a black rug.

A bedroom with a bed, a TV, a bedside table with a lamp, a door, and a window with curtains.

20. Large, modern house with all the comforts of home in a perfect location.

Large, modern house with all the comforts of home in a perfect location.

Des Moines

10.0 out of 10, Exceptional, (2 reviews)

10/10

Exceptional

(2 reviews)

"Clean, beautiful home."

Shayla

The price is ￥23,685

￥23,685

￥43,151 total

includes taxes & fees

Oct 18 - Oct 19

Large, modern house with all the comforts of home in a perfect location.

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Central Iowa Hotel Reviews

Stoney Creek Hotel Des Moines - Johnston

10/10 Excellent

"NA"

Rachel V 1-night trip

Posted 1 hour ago

Stoney Creek Hotel Des Moines - Johnston

Hotel Fort Des Moines, Curio Collection by Hilton

10/10 Excellent

"Really cool hotel with history. Great location and clean nice room."

Laura 1-night trip

Posted 1 hour ago

Hotel Fort Des Moines, Curio Collection by Hilton

La Quinta by Wyndham Altoona Des Moines

10/10 Excellent

"We have stayed here previously and came back because it was comfortable and conveniently located."

george 2-night trip

Posted 1 hour ago

La Quinta by Wyndham Altoona Des Moines

GrandStay Hotel & Suites

10/10 Excellent

"Clean and well kept. Convenient location."

Stephanie 1-night trip

Posted 7 hours ago

GrandStay Hotel & Suites

Des Lux Hotel

10/10 Excellent

"Decor and bar were great- don’t forget your swimsuit - nice hot tub!"

Susan 1-night trip

Posted 17 hours ago

Des Lux Hotel

Wildwood Lodge

10/10 Excellent

"Lovely front desk ladies. Room 101 was a suite and first impression was that it was very clean and the carpet was pristine. The room felt like a premium lodge/cabin and very homey with the heater on for us. Comfy bed. Soft sheets. Good pillows. Breakfast was light and good quality."

John 1-night trip

Posted 22 hours ago

Wildwood Lodge

Comfort Inn & Suites Event Center

10/10 Excellent

"Great locations if attending a concert at Casey’s Center"

Tracey 1-night trip

Posted 1 day ago

Comfort Inn & Suites Event Center

Hampton Inn Des Moines-Airport

10/10 Excellent

"Good place to stay near the airport"

Steven 1-night trip

Posted 2 days ago

Hampton Inn Des Moines-Airport

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

8/10 Good

"The hot tub wasn’t working but over all was a good stay"

Keeva 1-night trip

Posted 7 days ago

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Find out more about Central Iowa

Central Iowa Vacation Homes information

Number of reviews	7,726
Accommodation	503 Vacation Homes
Lowest Price	￥11,125
Highest Price	￥22,518

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Book Vacation Homes in Central Iowa on Expedia.com

Search Vacation Homes in Central Iowa

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Central Iowa vacation homes

1. Sleeps 6, 3BR-3BA | Easy I-35 Access

2. 3BR-2BA, Sleeps 8 | Close to I-35

3. Sleeps 10 - 5BR - Minutes to Campus - Next to Park, Golf, Shopping

4. 3BR Getaway, Sleeps 6 | 2-3 Miles to ISU

5. Cozy 2-bedroom house in peaceful Colo with AC

6. Natural Nesting Grounds - Boone, IA

7. 1800s Home, Train-Themed Decor, Walk to Downtown & Attractions, Exclusive Perks

8. Enjoy a stylish experience at this centrally-located newly built home.

9. Entire Home-Beautiful 4BR, 3.5BA Retreat in Ankeny, Iowa 2 King Beds, Fenced, AC

10. Ankeny 3BR Duplex, King Bed, Workspace & Game Room

11. Entire Bungalow with Fenced-In Yard! Sleeps 6 & Pet-Friendly, Central Des Moines

12. Spacious 4-bedroom house in Ankeny. For family, friends and business travelers.

13. The Rehoboth- Iowa -Entire Home, 4BR- Deluxe & Elegant, Great Location near I-35

14. New Spacious 4-bedroom house in charming Ankeny with WiFi, AC-Prime Location

15. Natural Nook - Boone, IA

16. Huge Home, Gym, Game Room, Spa, BBQ, Near I-35

17. Ankeny’s Best/Hot tub/Theatre Room/Game Room

18. Farmhouse Oasis

19. Retro themed 2-bedroom house in Boone The Retro Rambler is pet friendly!

20. Large, modern house with all the comforts of home in a perfect location.

Find vacation rentals that suit your style

Top Central Iowa Hotel Reviews

Stoney Creek Hotel Des Moines - Johnston

Find out more about Central Iowa

Central Iowa Vacation Homes information

Explore a world of travel with Expedia