Central Iowa, IA Vacation Homes from ￥10,758

Central Iowa Vacation Homes
United States of America
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A historic building with a large central archway and a pond in the foreground.

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Our top choices for Central Iowa vacation homes

A kitchen with white cabinets, a wooden dining table, a white stove, and a microwave.

A modern kitchen with a wooden table, white chairs, a hanging light fixture, and a window with blinds.

A kitchen with wooden cabinets, a white stove, a microwave, and a dishwasher.

A bed with two pillows and a framed landscape painting above it.

1. Campus & Downtown - Near Starbucks - Netflix - 2Br/1Ba

Campus & Downtown - Near Starbucks - Netflix - 2Br/1Ba

Ames

10.0 out of 10, Exceptional, (63 reviews)

10/10

Exceptional

(63 reviews)

"Great location!"

Nancie F.

The price is ￥13,671

￥13,671

￥25,994 total

includes taxes & fees

Aug 24 - Aug 25

Campus & Downtown - Near Starbucks - Netflix - 2Br/1Ba

A hallway with a wooden bench, a 'Guest Book,' and a 'Happy Home' sign.

A living room with a brown leather sofa, a round coffee table, a TV mounted on the wall, a ceiling fan, and a window with curtains.

A bedroom with a bed, a ceiling fan, a nightstand, a clock, and a window with curtains.

A dining area with a table, chairs, and a ceiling fan.

2. Cozy 2-bedroom house in peaceful Colo with AC

Cozy 2-bedroom house in peaceful Colo with AC

Colo

The price is ￥21,458

￥21,458

￥44,895 total

includes taxes & fees

Aug 31 - Sep 1

Cozy 2-bedroom house in peaceful Colo with AC

A house with a brick exterior, a wooden staircase, and a pathway leading to the front door.

A kitchen with a wooden island, a microwave, and a dining area with chairs.

A compact kitchen with a dining table, chairs, a refrigerator, and a blue door.

A stone pathway leading to a house with a wooden deck and a staircase.

3. The Fox Den

The Fox Den

Ames

10.0 out of 10, Exceptional, (8 reviews)

10/10

Exceptional

(8 reviews)

"The Fox Den was a nice place to stay, clean and was as described in the ad. Would definitely stay here again."

Angela T.

The price is ￥10,444

￥10,444

￥24,161 total

includes taxes & fees

Aug 29 - Aug 30

The Fox Den

A compact living space with a dining area, kitchen, and a cozy seating area.

A hotel room with a bed, a desk with a chair, a lamp, and a wardrobe.

A small office space with a wooden cabinet, a desk, a chair, and a floor lamp.

A living room with a fireplace, a television, and a dining area.

4. Charming 2-bedroom house in Collins with AC, WiFi

Charming 2-bedroom house in Collins with AC, WiFi

Collins

8.0 out of 10, Very Good, (11 reviews)

8.0/10

Very Good

(11 reviews)

"Great little place and quiet. Clean and everything in working order"

Doug D.

The price is ￥16,451

￥16,451

￥25,619 total

includes taxes & fees

Sep 3 - Sep 4

Charming 2-bedroom house in Collins with AC, WiFi

A living room with a sofa, coffee table, and dining table. There are framed pictures on the wall, a lamp, and a plant.

A modern kitchen with white tiles, black cabinets, and a wooden countertop. There are shelves with kitchenware, a coffee maker, and a window with blinds.

A kitchen with white tiled walls, a coffee maker, and various glassware on shelves.

A two-story house with a front porch, a garage, and a well-maintained lawn with flowers.

5. Downtown & Campus Wifi with Netflix 2Br 1Ba

Downtown & Campus Wifi with Netflix 2Br 1Ba

Ames

10.0 out of 10, Exceptional, (22 reviews)

10/10

Exceptional

(22 reviews)

"Lovely place to stay for our short stop in Ames! Great location and everything was super accessible!"

Jennifer L.

The price is ￥15,895

￥15,895

￥28,484 total

includes taxes & fees

Sep 21 - Sep 22

Downtown & Campus Wifi with Netflix 2Br 1Ba

A dining area with a round table, four wooden chairs, and a vase with flowers.

A wooden front door with a glass panel, a small window to the left, and a wooden staircase leading up to the door.

A kitchen with white cabinets, a sink, and a potted plant on the countertop.

A modern kitchen with white cabinetry, a stainless steel sink, and a dishwasher.

6. Charming Franklin House: Close to Campus, Sleeps 6

Charming Franklin House: Close to Campus, Sleeps 6

Ames

10.0 out of 10, Exceptional, (19 reviews)

10/10

Exceptional

(19 reviews)

"Great little house in a quiet neighborhood near campus. Enjoyed our stay!"

Anonymous traveler

The price is ￥15,307

￥15,307

￥39,575 total

includes taxes & fees

Aug 24 - Aug 25

Charming Franklin House: Close to Campus, Sleeps 6

A dining area with a wooden table, chairs, and a decorative mirror. There are white paneled walls and a ceiling light fixture.

A compact kitchen with a marble countertop, a built-in cabinet with dishes, a sink, and a window with blinds.

A spacious living room with a large flat-screen TV, a black dresser with gold knobs, a green sofa, and a wooden coffee table.

A spacious living area with a staircase, a green sofa, a white armchair, a coffee table, and a floor lamp.

7. 3BR Getaway, Sleeps 6 | 2-3 Miles to ISU

3BR Getaway, Sleeps 6 | 2-3 Miles to ISU

Ames

9.8 out of 10, Exceptional, (20 reviews)

9.8/10

Exceptional

(20 reviews)

"Great location and great place!"

Molly S.

The price is ￥34,810

￥34,810

￥83,315 total

includes taxes & fees

Sep 3 - Sep 4

3BR Getaway, Sleeps 6 | 2-3 Miles to ISU

A living room with a fireplace, a sofa set, a coffee table, and a door with a stained glass design.

A kitchen with wooden cabinets, a stove, a sink, and a refrigerator.

A living room with a fireplace, sofa, and coffee table.

A two-story house with a brick facade, a chimney, and a garage.

8. 3BR-2BA, Sleeps 8 | Close to I-35

3BR-2BA, Sleeps 8 | Close to I-35

Ames

The price is ￥23,684

￥23,684

￥72,634 total

includes taxes & fees

Aug 24 - Aug 25

3BR-2BA, Sleeps 8 | Close to I-35

A spacious living room with hardwood floors, a chandelier, a dining table with chairs, and a sofa.

A single-story house with a front porch, a blue door, and a small front yard with potted plants.

A laundry room with a washing machine and dryer, a sink, and a window with sheer curtains.

A room with a large mirror leaning against a white door with glass panels, wooden flooring, a bed with floral pillows, and a wall decorated with framed pictures.

9. Natural Nesting Grounds - Boone, IA

Natural Nesting Grounds - Boone, IA

Boone

9.8 out of 10, Exceptional, (30 reviews)

9.8/10

Exceptional

(30 reviews)

"Very nicely decorated and comfortable. Lots of extras like creamer, coffee, drinks..."

Kevin

The price is ￥18,279

￥18,279

￥31,688 total

includes taxes & fees

Aug 27 - Aug 28

Natural Nesting Grounds - Boone, IA

A garden with a stream, rocks, and flowers.

A garden with a paved walkway, various plants, and a bench.

A log cabin interior with a sofa, armchairs, a coffee table, and a fireplace.

A stone fireplace with a fire, surrounded by decorative foliage and ornaments.

10. Beautiful Rustic Barn just waiting for you to kick back and relax.

Beautiful Rustic Barn just waiting for you to kick back and relax.

NEW VIRGINIA

10.0 out of 10, Exceptional, (413 reviews)

10/10

Exceptional

(413 reviews)

"The barn and grounds are immaculate. This place is enchanting. Stay here. You will not be disappointed. "

Barbara O.

The price is ￥15,537

￥15,537

￥27,330 total

includes taxes & fees

Aug 27 - Aug 28

Beautiful Rustic Barn just waiting for you to kick back and relax.

A living room with a blue sofa, a matching ottoman, a wooden coffee table, a patterned rug, and a fan with artwork.

A single-story house with a front porch, a visible staircase, and a large tree in the foreground.

An outdoor patio with a table and chairs, a large umbrella, and a wooden fence in the background.

A hotel room with a bed, a television mounted on the wall displaying various channels, and a window with blinds.

11. Entire Bungalow with Fenced-In Yard! Sleeps 6 & Pet-Friendly, Central Des Moines

Entire Bungalow with Fenced-In Yard! Sleeps 6 & Pet-Friendly, Central Des Moines

Des Moines

10.0 out of 10, Exceptional, (31 reviews)

10/10

Exceptional

(31 reviews)

"Loved the tiger theme. This bungalow was conveniently located in an historic neighborhood, only 16-20 minutes from the state fair. I wish my sister had come with her dog because the place was well-adapted for traveling pups!"

Sarah

The price is ￥19,490

￥19,490

￥29,839 total

includes taxes & fees

Aug 26 - Aug 27

Entire Bungalow with Fenced-In Yard! Sleeps 6 & Pet-Friendly, Central Des Moines

A spacious living area with a modern kitchen, a dining area, and a large window providing natural light.

A modern living room with a fireplace, a glass coffee table, and comfortable seating.

A modern kitchen with white cabinets, stainless steel appliances, and a central island with bar stools.

A modern kitchen with a central island, white cabinetry, and blue chairs.

12. Entire Home-Beautiful 4BR, 3.5BA Retreat in Ankeny, Iowa 2 King Beds, Fenced, AC

Entire Home-Beautiful 4BR, 3.5BA Retreat in Ankeny, Iowa 2 King Beds, Fenced, AC

Ankeny

9.6 out of 10, Exceptional, (24 reviews)

9.6/10

Exceptional

(24 reviews)

"Wonderful stay. Close to tons of restaurants"

Lisa N.

The price is ￥24,637

￥24,637

￥56,967 total

includes taxes & fees

Sep 8 - Sep 9

Entire Home-Beautiful 4BR, 3.5BA Retreat in Ankeny, Iowa 2 King Beds, Fenced, AC

A two-story house with a front porch, a garage, and a small shed.

A room with a wooden floor, a bed with a red blanket, a bedside table, and a mirror on the wall.

A dining table set with plates, cups, and cutlery, a vase with flowers, and a window with curtains.

13. 1800s Home, Train-Themed Decor, Walk to Downtown & Attractions, Exclusive Perks

1800s Home, Train-Themed Decor, Walk to Downtown & Attractions, Exclusive Perks

Boone

10.0 out of 10, Exceptional, (66 reviews)

10/10

Exceptional

(66 reviews)

"We had a very nice and relaxing stay. There were many thoughtful amenities that we were greatful for. Beds were comfortable, temperature was easy to regulate, kitchen well equipped."

Sarah W.

The price is ￥31,784

￥31,784

￥40,762 total

includes taxes & fees

Aug 24 - Aug 25

1800s Home, Train-Themed Decor, Walk to Downtown & Attractions, Exclusive Perks

A residential house with a well-maintained lawn, a stone pathway, and a variety of trees and shrubs.

A compact kitchen with a built-in refrigerator and freezer, a window with a view of trees, and a countertop with a coffee maker and a toy car.

A patio with a stone table, wooden chairs, and a portable grill.

A spacious attic room with a brown leather couch, a plaid sofa, a dining table with chairs, and a ceiling fan.

14. 1-bedroom, 3 Gig-Fiber WiFi, timbered/view setting in WDM near RecPlex/DMU

1-bedroom, 3 Gig-Fiber WiFi, timbered/view setting in WDM near RecPlex/DMU

West Des Moines

9.2 out of 10, Wonderful, (14 reviews)

9.2/10

Wonderful

(14 reviews)

"Spacious accommodations, clean, and excellent location in a quiet area. Host, Clayton, was very responsive. "

John S.

The price is ￥16,451

￥16,451

￥25,548 total

includes taxes & fees

Aug 27 - Aug 28

1-bedroom, 3 Gig-Fiber WiFi, timbered/view setting in WDM near RecPlex/DMU

A kitchen with white cabinets, a stainless steel refrigerator, a double sink, and a window with a view of a wooden house.

A bedroom with a bed, a window, a plant, and a door leading to another room.

A two-story house surrounded by a garden with various flowers.

A picnic setup with a fire, marshmallows, and chocolate bars on a wooden table in a park area with stone buildings in the background.

15. The Rock House- The coziest Pella cottage retreat w/ firepit

The Rock House- The coziest Pella cottage retreat w/ firepit

Pella

10.0 out of 10, Exceptional, (87 reviews)

10/10

Exceptional

(87 reviews)

"We had a wonderful stay! Such a cute little house with all of the amenities!"

Matthew and Jennifer S.

The price is ￥20,996

￥20,996

￥43,276 total

includes taxes & fees

Sep 7 - Sep 8

The Rock House- The coziest Pella cottage retreat w/ firepit

A single-story house with a front porch, a small front yard, and a driveway.

16. Natural Nook - Boone, IA

Natural Nook - Boone, IA

Boone

8.0 out of 10, Very Good, (1 review)

8.0/10

Very Good

(1 review)

"The kitchen floor slopes and the bed is pretty high if you are vertically challenged otherwise nice place to stay"

brad g.

The price is ￥16,690

￥16,690

￥29,552 total

includes taxes & fees

Aug 23 - Aug 24

Natural Nook - Boone, IA

A modern kitchen with a central island, bar stools, stainless steel appliances, and a dining area in the background.

A modern living room with a grey sofa, an orange armchair, and a wooden coffee table.

A modern kitchen with a central island, stainless steel appliances, and a dining area with a table and chairs.

17. Spacious 5-bedroom house with AC and WiFi in fantastic NE Ankeny

Spacious 5-bedroom house with AC and WiFi in fantastic NE Ankeny

Ankeny

10.0 out of 10, Exceptional, (16 reviews)

10/10

Exceptional

(16 reviews)

"Great house, very nicely decorated and very comfortable beds. "

Kasey F.

The price is ￥37,353

￥37,353

￥73,880 total

includes taxes & fees

Sep 21 - Sep 22

Spacious 5-bedroom house with AC and WiFi in fantastic NE Ankeny

A kitchen with wooden cabinets, a stove, and various kitchen appliances.

A house with a covered porch, two bicycles, and a door with a window.

A living room with a floral sofa, a wooden coffee table, a patterned rug, a staircase, and a flat-screen TV mounted on the wall.

A bedroom with a bed, a nightstand, a lamp, and two windows with curtains.

18. The Hen House Country Living with Farm Life Appeal Indianola, IA

The Hen House Country Living with Farm Life Appeal Indianola, IA

Indianola

10.0 out of 10, Exceptional, (17 reviews)

10/10

Exceptional

(17 reviews)

"Loved it, every thing was awesome."

Adam b.

The price is ￥21,458

￥21,458

￥30,542 total

includes taxes & fees

Sep 1 - Sep 2

The Hen House Country Living with Farm Life Appeal Indianola, IA

A modern kitchen with white cabinets, granite countertops, a microwave, stove, and a dishwasher.

A hallway with a wooden floor, a white bench with a mirror, and a black rug.

A dining area with a long table, chairs, a vase with flowers, and a door in the background.

A black door with a colorful welcome mat and a wreath.

19. Large, modern house with all the comforts of home in a perfect location.

Large, modern house with all the comforts of home in a perfect location.

Des Moines

10.0 out of 10, Exceptional, (1 review)

10/10

Exceptional

(1 review)

"Clean, beautiful home."

Shayla

The price is ￥25,432

￥25,432

￥45,218 total

includes taxes & fees

Sep 21 - Sep 22

Large, modern house with all the comforts of home in a perfect location.

A modern kitchen with a central island, a dining area, and a living room with a sofa and decorative pillows.

A modern kitchen with a central island, bar stools, stainless steel appliances, and pendant lighting.

A dining area with a wooden table and chairs, a vase with flowers, and a white door in the background.

A wooden staircase with a railing leading to a porch area.

20. Enjoy a stylish experience at this centrally-located newly built home.

Enjoy a stylish experience at this centrally-located newly built home.

Ankeny

10.0 out of 10, Exceptional, (6 reviews)

10/10

Exceptional

(6 reviews)

"Newly furnished, clean, close to activities. Would stay again!"

Liz D.

The price is ￥20,743

￥20,743

￥48,869 total

includes taxes & fees

Aug 24 - Aug 25

Enjoy a stylish experience at this centrally-located newly built home.

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Central Iowa Hotel Reviews

Days Inn & Suites by Wyndham Des Moines Airport

10/10 Excellent

"Nice rooms, helpful staff, and good price. Always a go-to when we’re in the area"

Alexandria 1-night trip

Posted 4 hours ago

Days Inn & Suites by Wyndham Des Moines Airport

Sonesta Essential Des Moines

8/10 Good

"It was clean and reasonable for the price. Staff however could be a little more helpful in explaining breakfast times and having room ready at time of check-in."

Letisha 1-night trip

Posted 6 hours ago

Sonesta Essential Des Moines

GrandStay Hotel & Suites

10/10 Excellent

"This is a modern, bright, well maintained hotel with a very nice pool and a gigantic hot tub. The breakfast was one of the better ones I have had. The price for the stay was very reasonable and much cheaper than the hotels closer to Des Moines. A wonderful stay."

Glenn Hansen 1-night trip

Posted 6 hours ago

GrandStay Hotel & Suites

Stoney Creek Hotel Des Moines - Johnston

10/10 Excellent

"L"

Cristina 2-night trip

Posted 10 hours ago

Stoney Creek Hotel Des Moines - Johnston

AmericInn by Wyndham Des Moines Airport

10/10 Excellent

"very good people and property"

danny 2-night trip

Posted 14 hours ago

AmericInn by Wyndham Des Moines Airport

Gateway Hotel and Conference Center at Iowa State University

10/10 Excellent

"Very nice staff. Convenient hotel! Close to ISU.!"

Ruth 5-night trip

Posted 14 hours ago

Gateway Hotel and Conference Center at Iowa State University

Motel 6 West Des Moines, IA

10/10 Excellent

"Everything is awesome!"

Marvin 1-night trip

Posted 1 day ago

Motel 6 West Des Moines, IA

Des Lux Hotel

10/10 Excellent

"Clean room and great breakfast"

Tehya 1-night trip

Posted 1 day ago

Des Lux Hotel

AmericInn by Wyndham Johnston Des Moines

8/10 Good

"love it"

Byaombe 1-night trip

Posted 2 days ago

AmericInn by Wyndham Johnston Des Moines

Find out more about Central Iowa

Central Iowa Vacation Homes information

Number of reviews	12,240
Accommodation	507 Vacation Homes
Lowest Price	￥10,758
Highest Price	￥22,611

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Book Vacation Homes in Central Iowa on Expedia.com

Search Vacation Homes in Central Iowa

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Central Iowa vacation homes

1. Campus & Downtown - Near Starbucks - Netflix - 2Br/1Ba

2. Cozy 2-bedroom house in peaceful Colo with AC

3. The Fox Den

4. Charming 2-bedroom house in Collins with AC, WiFi

5. Downtown & Campus Wifi with Netflix 2Br 1Ba

6. Charming Franklin House: Close to Campus, Sleeps 6

7. 3BR Getaway, Sleeps 6 | 2-3 Miles to ISU

8. 3BR-2BA, Sleeps 8 | Close to I-35

9. Natural Nesting Grounds - Boone, IA

10. Beautiful Rustic Barn just waiting for you to kick back and relax.

11. Entire Bungalow with Fenced-In Yard! Sleeps 6 & Pet-Friendly, Central Des Moines

12. Entire Home-Beautiful 4BR, 3.5BA Retreat in Ankeny, Iowa 2 King Beds, Fenced, AC

13. 1800s Home, Train-Themed Decor, Walk to Downtown & Attractions, Exclusive Perks

14. 1-bedroom, 3 Gig-Fiber WiFi, timbered/view setting in WDM near RecPlex/DMU

15. The Rock House- The coziest Pella cottage retreat w/ firepit

16. Natural Nook - Boone, IA

17. Spacious 5-bedroom house with AC and WiFi in fantastic NE Ankeny

18. The Hen House Country Living with Farm Life Appeal Indianola, IA

19. Large, modern house with all the comforts of home in a perfect location.

20. Enjoy a stylish experience at this centrally-located newly built home.

Find vacation rentals that suit your style

Top Central Iowa Hotel Reviews

Days Inn & Suites by Wyndham Des Moines Airport

Find out more about Central Iowa

Central Iowa Vacation Homes information

Explore a world of travel with Expedia