Find hotels in Carlisle, IA from ￥8,871

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 9 - Dec 10
Tomorrow
Dec 10 - Dec 11
This weekend
Dec 12 - Dec 14
Next weekend
Dec 19 - Dec 21

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Carlisle hotels

Standard Room, 1 King Bed | Desk, iron/ironing board, free cribs/infant beds, rollaway beds
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2.0 star property
Greater South Side
8.6 out of 10, Excellent, (1680)
"Had a great stay and was impressed with the staff and the hotel. Will stay again!"
United States
Kevin
The price is ￥9,786
￥10,960 total
includes taxes & fees
Dec 24 - Dec 25
Days Inn & Suites by Wyndham Des Moines Airport
Indoor spa tub
Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

2.5 star property
Johnston
9.0 out of 10, Wonderful, (1791)
"Staff friendly. Hotel clean, cute and cozy. "
United States
Nick
The price is ￥15,174
￥16,995 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Stoney Creek Hotel Des Moines - Johnston
Reception
AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport

2.5 star property
Greater South Side
7.8 out of 10, Good, (1002)
"The staff was great, check in was fast and easy"
United States
Joel
The price is ￥9,667
￥10,828 total
includes taxes & fees
Dec 30 - Dec 31
AmericInn by Wyndham Des Moines Airport
Room, Two Queen Beds, Accessible Roll in Shower, Non Smoking | Premium bedding, down comforters, pillowtop beds, desk
Cobblestone Hotel & Suites - Knoxville

Cobblestone Hotel & Suites - Knoxville

2.5 star property
Knoxville
9.2 out of 10, Wonderful, (471)
"It was easy to check in and our room was very comfortable and clean."
United States
Mary
The price is ￥13,881
￥15,548 total
includes taxes & fees
Dec 10 - Dec 11
Cobblestone Hotel & Suites - Knoxville
Property amenity
Country Inn & Suites by Radisson, Indianola, IA

Country Inn & Suites by Radisson, Indianola, IA

2.5 star property
Indianola
9.0 out of 10, Wonderful, (710)
"I stay at this property multiple times a year and have always had a positive experience. "
United States
John
The price is ￥17,082
￥19,131 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Country Inn & Suites by Radisson, Indianola, IA
Indoor pool
Sleep Inn & Suites Pleasant Hill - Des Moines

Sleep Inn & Suites Pleasant Hill - Des Moines

2.5 star property
Pleasant Hill
7.8 out of 10, Good, (954)
"good place to stay"
United States
Tammy
The price is ￥12,432
￥13,924 total
includes taxes & fees
Dec 14 - Dec 15
Sleep Inn & Suites Pleasant Hill - Des Moines
Food and drink
Homewood Suites by Hilton Des Moines Airport

Homewood Suites by Hilton Des Moines Airport

3.0 star property
Des Moines
9.4 out of 10, Exceptional, (607)
"Everything looked clean and the staff was very kind. Will stay here again for sure. "
United States
Margaret
The price is ￥17,832
￥19,973 total
includes taxes & fees
Dec 20 - Dec 21
Homewood Suites by Hilton Des Moines Airport
Lobby
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 star property
Downtown Des Moines
9.6 out of 10, Exceptional, (1059)
"Favorite hotel in DM. Great location, great staff."
United States
Susan
The price is ￥20,120
￥22,534 total
includes taxes & fees
Dec 15 - Dec 16
Hotel Fort Des Moines, Curio Collection by Hilton
Exterior
Embassy Suites Hotel Des Moines Downtown

Embassy Suites Hotel Des Moines Downtown

3.5 star property
Downtown Des Moines
8.2 out of 10, Very Good, (1053)
"Rooms were spacious. However, the double beds seemed a bit small. Really liked the breakfast that was offered in the morning. It had a great selection of different breakfast items. Overall, good experience. "
United States
Darlene
The price is ￥18,570
￥20,799 total
includes taxes & fees
Dec 22 - Dec 23
Embassy Suites Hotel Des Moines Downtown
Exterior
Fairfield Inn & Suites by Marriott Des Moines Downtown

Fairfield Inn & Suites by Marriott Des Moines Downtown

4.0 star property
Downtown Des Moines
9.0 out of 10, Wonderful, (392)
"Clean room, quiet, excellent breakfast. "
United States
Randy
The price is ￥13,865
￥15,528 total
includes taxes & fees
Dec 28 - Dec 29
Fairfield Inn & Suites by Marriott Des Moines Downtown
Free daily continental breakfast
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 star property
Greater South Side
8.8 out of 10, Excellent, (1007)
"All was great. "
United States
Jason
The price is ￥16,078
￥18,007 total
includes taxes & fees
Dec 15 - Dec 16
Hampton Inn Des Moines-Airport
Lobby
Hilton Garden Inn Des Moines/Urbandale

Hilton Garden Inn Des Moines/Urbandale

3.0 star property
Johnston
9.0 out of 10, Wonderful, (1000)
"It was very quiet even tho we were next to the interstate."
United States
James
The price is ￥14,831
￥16,610 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hilton Garden Inn Des Moines/Urbandale
Lounge
AC Hotel Des Moines East Village

AC Hotel Des Moines East Village

3.0 star property
Downtown Des Moines
9.2 out of 10, Wonderful, (405)
"Hotel was clean and staff friendly."
United States
Cathy
The price is ￥23,455
￥26,270 total
includes taxes & fees
Dec 20 - Dec 21
AC Hotel Des Moines East Village
Free daily continental breakfast
Quality Inn Indianola

Quality Inn Indianola

2.5 star property
Indianola
7.6 out of 10, Good, (512)
"The staff was kind and the hotel rooms clean"
United States
Stephanie
The price is ￥10,369
￥11,613 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Quality Inn Indianola
Standard Room, 2 Queen Beds, Non Smoking | Hypo-allergenic bedding, desk, blackout drapes, soundproofing
Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport

2.5 star property
Greater South Side
7.4 out of 10, Good, (1008)
"Best location for passengers traveling on flights"
United States
Sai Lakshmi
The price is ￥9,815
￥10,993 total
includes taxes & fees
Dec 16 - Dec 17
Quality Inn & Suites Des Moines Airport
Exterior
Econo Lodge Inn & Suites Fairgrounds

Econo Lodge Inn & Suites Fairgrounds

2.0 star property
Fairground
7.2 out of 10, Good, (1001)
"Nothing fancy, but the room was clean, and the bed was comfortable. The staff was friendly. I'd stay here again,"
United States
Teri
The price is ￥9,131
￥10,226 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Econo Lodge Inn & Suites Fairgrounds
Suite, Multiple Beds | Desk, iron/ironing board, rollaway beds, free WiFi
Sonesta Essential Des Moines

Sonesta Essential Des Moines

2.0 star property
Lovington
7.4 out of 10, Good, (1003)
"Clean room, nice staff. The only complaint is the breakfast."
United States
Lindsey
The price is ￥9,387
￥10,979 total
includes taxes & fees
Dec 20 - Dec 21
Sonesta Essential Des Moines
Minibar, in-room safe, individually decorated, individually furnished
Surety Hotel, Autograph Collection

Surety Hotel, Autograph Collection

4.0 star property
Downtown Des Moines
9.4 out of 10, Exceptional, (1001)
"Great hotel"
United States
Grant
The price is ￥22,434
￥25,126 total
includes taxes & fees
Dec 23 - Dec 24
Surety Hotel, Autograph Collection
Exterior
Hampton Inn & Suites Des Moines Downtown

Hampton Inn & Suites Des Moines Downtown

2.5 star property
Downtown Des Moines
8.6 out of 10, Excellent, (1008)
"Nice hotel and conveniently located"
United States
shane
The price is ￥13,585
￥15,215 total
includes taxes & fees
Dec 28 - Dec 29
Hampton Inn & Suites Des Moines Downtown
Free daily buffet breakfast
Hotel Pommier Indianola

Hotel Pommier Indianola

2.5 star property
Indianola
9.2 out of 10, Wonderful, (430)
"Everything was wonderful. "
United States
Garrett
The price is ￥11,812
￥13,230 total
includes taxes & fees
Dec 18 - Dec 19
Hotel Pommier Indianola
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Carlisle Hotel Reviews

Des Lux Hotel

Des Lux Hotel

10/10 Excellent
"Wonderful, friendly staff. Stunning lobby! The room was large and immaculate."
Jeannie 1-night trip
Posted 23 hours ago
Des Lux Hotel

More cheap stays in Carlisle

Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

7655 Office Plaza Dr N West Des Moines IA
The price is ￥7,920 per night from Dec 28 to Dec 29
￥7,920
￥8,871 total
Dec 28 - Dec 29
includes taxes & fees
7.8/10 Good! (699 reviews)

Frequently asked questions

Where is the best place for a stay in Carlisle?
Located 9.4 mi (15.2 km) from the heart of Carlisle, Hotel Fort Des Moines, Curio Collection by Hilton is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Home2 Suites by Hilton Des Moines at Drake University and Days Inn & Suites by Wyndham Des Moines Airport. See all available top hotels, or vacation rentals in Carlisle.
What are some of the best vacation home rentals that Carlisle has to offer?
SO MUCH FUN! ARCADE, PL TBL, PNG PNG, YARD GAMES, INDOOR AND OUTDOOR POOLS!!: Visitors like this Carlisle vacation home rental. It offers a fireplace, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind. See all vacation rentals in Carlisle.
If I need to cancel my hotel reservation in Carlisle, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If your reservation is non-refundable, you may still be able to cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Carlisle.
Where can I learn more about changing or cancelling my trip to Carlisle?
For more information about changing or cancelling your trip to Carlisle, click here.
What's the best hotel for staying near Des Moines International Airport (DSM)?
Days Inn & Suites by Wyndham Des Moines Airport is a popular hotel, featuring free breakfast and an indoor pool. It's located a short 0.5 mi (0.7 km) from Des Moines Intl. Airport. Other good options near the airport are Ramada by Wyndham Des Moines Airport and Hampton Inn Des Moines Airport.
What is staying in Carlisle like?
Those traveling to Carlisle are sure to enjoy the sights to see and things to do. There are 818 hotels and other accommodations in the surrounding area. Find out more about Carlisle.
What is there to see in Carlisle?
Places to visit in the wider area include Blank Park Zoo, Iowa State Fairgrounds, and Principal Park. You'll also find Iowa State Capitol Building and Wooly's in the area. Check out what more to see and do in Expedia's Carlisle guide.
What's the seasonal weather like in Carlisle?
The hottest months are usually July and August with an average temp of 72°F, while the coldest months are January and February with an average of 29°F. The snowiest months in Carlisle are January, February, November, and March, with each month seeing an average of 9 inches of snowfall.

Explore a world of travel with Expedia