A red train on tracks, palm trees, and modern buildings.

Find 4 Star Hotels in Central San Diego, CA from ￥21,998

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Check availability on Central San Diego 4 Star Hotels

Tonight
Oct 23 - Oct 24
Tomorrow
Oct 24 - Oct 25
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Our top choices for Central San Diego 4-star hotels

An outdoor patio with a stone fire pit, outdoor seating, string lights, and a tall, narrow heater.
A beach with clear skies, a rocky cliff, and a lighthouse in the distance.
A hotel room with a large bed, a chair, a nightstand, and a lamp.
A swimming pool with a visible water filtration system and a tiled edge.

1. Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
University City
United States
Kunta
￥25,179
￥33,407 total
includes taxes & fees
Oct 31 - Nov 1
Embassy Suites by Hilton San Diego La Jolla
A large swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a building with a striped facade.
A bar area with a glass ceiling, a central bar counter, and multiple stools.
A dimly lit room with patterned walls, a wooden table, and a chair.
A checkered floor with round tables and chairs, a patterned ceiling, and large windows.

2. Lafayette Hotel & Club

Lafayette Hotel & Club
University Heights
United States
Stacey
￥42,359
￥48,689 total
includes taxes & fees
Nov 23 - Nov 24
Lafayette Hotel & Club
A spacious lobby with modern furniture, large windows, and a high ceiling with hanging lights.
A modern interior with wooden panel ceilings, patterned seating, and a central bar area.
A pathway leading to a building labeled "LEGACY Hotel."
A hotel room with a large bed, a wooden nightstand, a bench, a desk with a TV, and a chair.

3. Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
Mission Valley
United States
christopher
￥25,390
￥29,185 total
includes taxes & fees
Nov 8 - Nov 9
Legacy Resort Hotel & Spa
A spacious lobby with a modern staircase, comfortable seating, and large windows offering natural light.
An outdoor dining area with tables set for two, string lights overhead, and a view of a building in the background.
A modern lobby with a large window, two sofas, and two black planters with plants.
An outdoor wedding venue with rows of chairs, floral centerpieces, and string lights.

4. Hilton San Diego Mission Valley

Hilton San Diego Mission Valley
Mission Valley
Mexico
LUIS
￥20,434
￥23,487 total
includes taxes & fees
Nov 1 - Nov 2
Hilton San Diego Mission Valley
An outdoor lounge area with seating, a fire feature, and a pool in the background.
A hotel with a large pool surrounded by lounge chairs and umbrellas, palm trees, and a well-lit building facade.
A spacious lobby with a bar area, leather armchairs, and a reception desk.
A modern restaurant with multiple seating areas, including booths and tables. There are hanging lights and a variety of plants.

5. Town and Country San Diego

Town and Country San Diego
Mission Valley
United States
Nelly
￥24,989
￥34,138 total
includes taxes & fees
Nov 24 - Nov 25
Town and Country San Diego
An outdoor dining area with tables and chairs, a fire feature, and a bar area with a stone wall and shelves.
A hotel entrance with a covered outdoor seating area, palm trees, and a car parked in front.
A spacious indoor lounge area with a central fire feature, multiple seating arrangements, and a bar area.
A spacious gym with various exercise equipment, large windows, and a wooden floor.

6. San Diego Marriott La Jolla

San Diego Marriott La Jolla
University City
United States
Josh
￥29,006
￥33,363 total
includes taxes & fees
Oct 31 - Nov 1
San Diego Marriott La Jolla
A swimming pool with lounge chairs and a waterfall feature, surrounded by palm trees and a building with multiple balconies.
A modern hotel with a prominent tower, multiple floors, and a well-lit entrance.
A modern bar area with a long counter, multiple hanging pendant lights, and a bar stocked with bottles and glasses.
A modern lobby with a round table and four chairs, a reception desk, and a large window.

7. San Diego Marriott Mission Valley

San Diego Marriott Mission Valley
Mission Valley
United States
Eva
￥26,511
￥30,474 total
includes taxes & fees
Nov 22 - Nov 23
San Diego Marriott Mission Valley
A spacious hotel lobby with a long reception desk, multiple seating areas, and large windows offering views of the outdoors.
A hotel room with two beds, a TV, a desk, and a chair.
A modern hotel with a flat roof, large windows, and a sign reading "DOLLYWOOD HOTEL".
A poolside area with a fire pit, lounge chairs, and a pool.

8. DoubleTree by Hilton San Diego - Hotel Circle

DoubleTree by Hilton San Diego - Hotel Circle
Mission Valley
United States
Ramiro
￥19,138
￥21,998 total
includes taxes & fees
Nov 2 - Nov 3
DoubleTree by Hilton San Diego - Hotel Circle
An outdoor seating area with wicker chairs and a fire pit, surrounded by palm trees and string lights.
A grand lobby with a marble floor, a central table with floral arrangements, a staircase, and potted plants.
A poolside area with a concrete pool, lounge chairs, and a wooden deck.
A modern dining area with a large table, chairs, and hanging plants.

9. DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
Mission Valley
United States
Jenelle
￥21,201
￥24,370 total
includes taxes & fees
Nov 22 - Nov 23
DoubleTree by Hilton Hotel San Diego - Mission Valley
An outdoor seating area with sofas, a fire pit, and tables covered with blue tablecloths.
A hotel room with a large bed, a sofa, a round stone accent, and a view of buildings through large windows.
A rooftop swimming pool with sun loungers and umbrellas, surrounded by a landscaped area with trees and a tennis court.
A spacious library with high ceilings, bookshelves, and a central staircase.

10. Hyatt Regency La Jolla

Hyatt Regency La Jolla
University City
United States
lisa
￥33,256
￥44,008 total
includes taxes & fees
Nov 15 - Nov 16
Hyatt Regency La Jolla
A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.
A modern bedroom with a large bed, a nightstand, a wall-mounted lamp, and a window with curtains.
A modern reception desk with a glass top, a large window offering a view, and a potted plant.
An outdoor seating area with sofas and chairs, a wooden staircase, and potted plants.

11. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
Middletown
United States
Donavin
￥18,165
￥25,810 total
includes taxes & fees
Nov 2 - Nov 3
City24 Hotel Little Italy Mission Hills
A pool area with lounge chairs and umbrellas, surrounded by palm trees and a hilly landscape.
Property amenity
A modern room with a glass dining table, two bar stools, a sofa, and a TV stand with decorative items.
A hotel room with a large bed, a TV, a desk with a chair, and a view of the city through large windows.

12. Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel
Mission Valley
United States
Leanna
￥28,055
￥32,248 total
includes taxes & fees
Oct 28 - Oct 29
Sheraton Mission Valley San Diego Hotel
Room
Breakfast area
Private kitchen
Room

13. Residence Inn by Marriott San Diego Mission Valley

Residence Inn by Marriott San Diego Mission Valley
Mission Valley
United States
Kabnne
Residence Inn by Marriott San Diego Mission Valley
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Learn more about Central San Diego

Explore the seaside area of Central San Diego—a zoo, sports teams, and popular sights like San Diego Zoo.

See all hotels in Central San Diego
A historic cathedral with intricate architecture, a prominent bell tower, and a blue-domed structure.
Photo by Bilen Z

Top Central San Diego Hotel Reviews

Lafayette Hotel & Club

Lafayette Hotel & Club

8/10 Good
"The rooms are so unique and the attention to detail is fantastic."
Nicholas 2-night trip
Posted 8 hours ago
Lafayette Hotel & Club

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Central San Diego?
Expedia can help you easily locate the ideal 4-star hotel for your vacation in Central San Diego. Use our filter tool to tailor your search by things like price, conveniences and hotel star rating and get access to terrific deals in a couple of clicks.
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What's the difference between 5-star and 4-star hotels in Central San Diego?
Offering a welcoming guest experience and upscale surroundings, 4-star hotels are a wonderful option for your Central San Diego escape. These kinds of stays generally feature loads of handy amenities that make it easy to unpack and unwind — think complimentary bathrobes, restaurants and pools. Or live in the lap of luxury at a 5-star hotel designed to spoil you with high-end perks and amenities. A personalized service, complimentary toiletries and gourmet dining are typically featured at these plush retreats.
Does Central San Diego have any 4-star all-inclusive resorts?
Finding your dream resort in Central San Diego is as simple as entering your travel dates and selecting our "All inclusive" filter. Stay and play where everything is already taken care of like your accommodations, food, activities and entertainment, or choose a standard 4-star resort in or around this leading destination.

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