A red train on tracks, palm trees, and modern buildings.

Find 4 Star Hotels in Central San Diego, CA from ￥22,192

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Check availability on Central San Diego 4 Star Hotels

Tonight
Oct 16 - Oct 17
Tomorrow
Oct 17 - Oct 18
This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Our top choices for Central San Diego 4-star hotels

An outdoor lounge area with seating, a fire feature, and a pool in the background.
A spacious lobby with a bar area, leather armchairs, and a reception desk.
A modern restaurant with multiple seating areas, including booths and tables. There are hanging lights and a variety of plants.
A stone wall with a neon sign that reads "Tom & Jerry."

1. Town and Country San Diego

Town and Country San Diego
Mission Valley
United States
Nelly
￥28,444
￥38,147 total
includes taxes & fees
Nov 10 - Nov 11
Town and Country San Diego
A bar area with a glass ceiling, a central bar counter, and multiple stools.
A checkered floor with round tables and chairs, a patterned ceiling, and large windows.
A large swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a building with a striped facade.
A luxurious interior with a large chandelier, patterned sofas, and a view of a cityscape through a large window.

2. Lafayette Hotel & Club

Lafayette Hotel & Club
University Heights
United States
Laurie
￥36,237
￥41,652 total
includes taxes & fees
Nov 16 - Nov 17
Lafayette Hotel & Club
An outdoor seating area with wicker chairs and a fire pit, surrounded by palm trees and string lights.
A poolside area with a concrete pool, lounge chairs, and a wooden deck.
A modern dining area with a large table, chairs, and hanging plants.
A grand lobby with a marble floor, a central table with floral arrangements, a staircase, and potted plants.

3. DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
Mission Valley
United States
Laura
￥22,711
￥26,105 total
includes taxes & fees
Nov 8 - Nov 9
DoubleTree by Hilton Hotel San Diego - Mission Valley
An outdoor dining area with tables and chairs, a fire feature, and a bar area with a stone wall and shelves.
A spacious indoor lounge area with a central fire feature, multiple seating arrangements, and a bar area.
A hotel entrance with a covered outdoor seating area, palm trees, and a car parked in front.
A spacious gym with various exercise equipment, large windows, and a wooden floor.

4. San Diego Marriott La Jolla

San Diego Marriott La Jolla
University City
United States
Josh
￥29,245
￥33,638 total
includes taxes & fees
Oct 30 - Oct 31
San Diego Marriott La Jolla
An outdoor dining area with tables set for two, string lights overhead, and a view of a building in the background.
A modern lobby with a large window, two sofas, and two black planters with plants.
An outdoor wedding venue with rows of chairs, floral centerpieces, and string lights.
A modern interior with a seating area featuring round tables and chairs, a large mirror, and a unique ceiling light fixture.

5. Hilton San Diego Mission Valley

Hilton San Diego Mission Valley
Mission Valley
United States
Ashley
￥20,603
￥23,683 total
includes taxes & fees
Nov 1 - Nov 2
Hilton San Diego Mission Valley
An outdoor patio with a stone fire pit, outdoor seating, string lights, and a tall, narrow heater.
A multi-level hotel lobby with dining areas, a reception desk, and a large TV screen.
A hotel room with a large bed, a chair, a nightstand, and a lamp.
A swimming pool with a visible water filtration system and a tiled edge.

6. Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
University City
United States
Kunta
￥28,086
￥36,788 total
includes taxes & fees
Oct 24 - Oct 25
Embassy Suites by Hilton San Diego La Jolla
A spacious lobby with modern furniture, large windows, and a high ceiling with hanging lights.
A swimming pool with blue lounge chairs and umbrellas, surrounded by a building with balconies.
A pathway leading to a building labeled "LEGACY Hotel."
A hotel room with a large bed, a wooden nightstand, a bench, a desk with a TV, and a chair.

7. Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
Mission Valley
United States
christopher
￥25,873
￥29,739 total
includes taxes & fees
Oct 18 - Oct 19
Legacy Resort Hotel & Spa
A spacious hotel lobby with a long reception desk, multiple seating areas, and large windows offering views of the outdoors.
A hotel room with two beds, a TV, a desk, and a chair.
A poolside area with a fire pit, lounge chairs, and a pool.
A hotel room with two beds, a nightstand with a lamp, a framed picture on the wall, and a view through an open door.

8. DoubleTree by Hilton San Diego - Hotel Circle

DoubleTree by Hilton San Diego - Hotel Circle
Mission Valley
United States
Ramiro
￥19,307
￥22,192 total
includes taxes & fees
Oct 27 - Oct 28
DoubleTree by Hilton San Diego - Hotel Circle
A swimming pool with lounge chairs and a waterfall feature, surrounded by palm trees and a building with multiple balconies.
A modern hotel with a prominent tower, multiple floors, and a well-lit entrance.
A modern bar area with a long counter, multiple hanging pendant lights, and a bar stocked with bottles and glasses.
A modern outdoor seating area with a wooden wall, a hanging chair, and a large potted plant.

9. San Diego Marriott Mission Valley

San Diego Marriott Mission Valley
Mission Valley
United States
Eva
￥25,138
￥28,895 total
includes taxes & fees
Oct 25 - Oct 26
San Diego Marriott Mission Valley
An outdoor seating area with sofas, a fire pit, and tables covered with blue tablecloths.
A rooftop swimming pool with sun loungers and umbrellas, surrounded by a landscaped area with trees and a tennis court.
A hotel room with two beds, a desk, a TV, and a window with a city view.
A gym with exercise equipment, mirrors, and a wall-mounted TV.

10. Hyatt Regency La Jolla

Hyatt Regency La Jolla
University City
United States
lisa
￥33,500
￥44,330 total
includes taxes & fees
Nov 15 - Nov 16
Hyatt Regency La Jolla
An outdoor patio with tables and chairs, string lights, and umbrellas.
Property amenity
A modern room with a glass dining table, two bar stools, a sofa, and a TV stand with decorative items.
A hotel room with a large bed, a TV, a desk with a chair, and a view of the city through large windows.

11. Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel
Mission Valley
United States
Leanna
￥28,300
￥32,530 total
includes taxes & fees
Oct 25 - Oct 26
Sheraton Mission Valley San Diego Hotel
A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.
A modern bedroom with a large bed, a nightstand, a wall-mounted lamp, and a window with curtains.
A modern reception desk with a glass top, a large window offering a view, and a potted plant.
A modern interior with concrete walls, wooden beams, and a central planter with plants.

12. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
Middletown
United States
Donavin
￥17,715
￥25,349 total
includes taxes & fees
Nov 2 - Nov 3
City24 Hotel Little Italy Mission Hills
BBQ/picnic area
Breakfast area
Private kitchen
Room

13. Residence Inn by Marriott San Diego Mission Valley

Residence Inn by Marriott San Diego Mission Valley
Mission Valley
United States
Kabnne
Residence Inn by Marriott San Diego Mission Valley
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Learn more about Central San Diego

Explore the seaside area of Central San Diego—a zoo, sports teams, and popular sights like San Diego Zoo.

See all hotels in Central San Diego
A historic cathedral with intricate architecture, a prominent bell tower, and a blue-domed structure.
Photo by Bilen Z

Top Central San Diego Hotel Reviews

Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

8/10 Good
"Good services staffs. But hotel not new & fresh enough."
Dung 2-night trip
Posted 3 hours ago
Hilton San Diego Mission Valley
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

10/10 Excellent
"The staff at reception could be a bit more attentive when it comes to checking out of the hotel."
Gary 3-night trip
Posted 8 hours ago
Legacy Resort Hotel & Spa
Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla

8/10 Good
"Love this place stayed there 20 times it’s starting to show a lot of wear and tear and I’m sad to see that"
Kent 1-night trip
Posted 1 day ago
Embassy Suites by Hilton San Diego La Jolla

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Central San Diego?
Expedia can help you easily locate the ideal 4-star hotel for your vacation in Central San Diego. Use our filter tool to tailor your search by things like price, conveniences and hotel star rating and get access to terrific deals in a couple of clicks.
  • Search for the lowest price from ￥22,192
What's the difference between 5-star and 4-star hotels in Central San Diego?
Offering a welcoming guest experience and upscale surroundings, 4-star hotels are a wonderful option for your Central San Diego escape. These kinds of stays generally feature loads of handy amenities that make it easy to unpack and unwind — think complimentary bathrobes, restaurants and pools. Or live in the lap of luxury at a 5-star hotel designed to spoil you with high-end perks and amenities. A personalized service, complimentary toiletries and gourmet dining are typically featured at these plush retreats.
Does Central San Diego have any 4-star all-inclusive resorts?
Finding your dream resort in Central San Diego is as simple as entering your travel dates and selecting our "All inclusive" filter. Stay and play where everything is already taken care of like your accommodations, food, activities and entertainment, or choose a standard 4-star resort in or around this leading destination.

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