Find hotels in Zona 16, Guatemala City

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Tonight
Dec 26 - Dec 27
Tomorrow
Dec 27 - Dec 28
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

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Our top choices for Zona 16 hotels

Exterior
Cayalá Lofts

Cayalá Lofts

Cayalá Lofts
3.5 star property
Zona 16
9.0 out of 10, Wonderful, (72)
"Everything is perfect staff they’re very nice specially with the check in they’re very helpful I’ll recommend it "
United States
MIRTA
The price is ￥12,220
￥16,741 total
includes taxes & fees
Dec 28 - Dec 29
Cayalá Lofts
Front of property
Cayalito Apart

Cayalito Apart

Cayalito Apart
3.0 star property
Zona 16
8.4 out of 10, Very Good, (9)
"Lugar muy agradable y limpio, lo recomiendo ampliamente :)"
Mexico
Luis donaldo
The price is ￥7,026
￥8,572 total
includes taxes & fees
Dec 28 - Dec 29
Cayalito Apart
Exterior
AC Hotel by Marriott Guatemala City

AC Hotel by Marriott Guatemala City

AC Hotel by Marriott Guatemala City
4.0 star property
Zona 16
8.6 out of 10, Excellent, (1001)
"Great place, great location"
United States
vicky
The price is ￥18,448
￥22,506 total
includes taxes & fees
Jan 4 - Jan 5, 2026
AC Hotel by Marriott Guatemala City
Indoor pool
Pink House 604

Pink House 604

Pink House 604
3.0 star property
Zona 16
8.0 out of 10, Very Good, (2)
"Clean "
United States
Rosa
The price is ￥12,801
￥16,154 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Pink House 604
3 outdoor pools, pool umbrellas
Hotel Soleil La Antigua

Hotel Soleil La Antigua

Hotel Soleil La Antigua
4.0 star property
29.9 km from Zona 16
8.6 out of 10, Excellent, (1001)
"Overall good place to stay. Not a fan of the no outside food or drink policy, but aside from that this is a very nice place. Staff is especially kind and helpful."
United States
Cesar
Hotel Soleil La Antigua
Terrace/patio
Los Pasos Boutique Hotel & Spa

Los Pasos Boutique Hotel & Spa

Los Pasos Boutique Hotel & Spa
4.5 star property
28.8 km from Zona 16
9.4 out of 10, Exceptional, (1003)
"Great stay "
United States
BETTE
The price is ￥24,456
￥31,056 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Los Pasos Boutique Hotel & Spa
View from room
Mestizo Antigua

Mestizo Antigua

Mestizo Antigua
4.0 star property
29.2 km from Zona 16
9.4 out of 10, Exceptional, (156)
"The breakfast was fresh and delicious "
United States
Patricia
The price is ￥26,068
￥31,803 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Mestizo Antigua
Free daily continental breakfast
Ciel-Luxe Hotels

Ciel-Luxe Hotels

Ciel-Luxe Hotels
3.5 star property
29.1 km from Zona 16
8.8 out of 10, Excellent, (351)
"Excellent customer service from the staff, great food, room was very clean and a block away from the park."
United States
Rodrigo
Ciel-Luxe Hotels
Exterior
Naif Boutique Hotel

Naif Boutique Hotel

Naif Boutique Hotel
3.0 star property
29.3 km from Zona 16
8.8 out of 10, Excellent, (375)
"Beautiful rooms and helpful staff in a very nicely centrally located hotel"
United States
Joe
The price is ￥19,324
￥23,576 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Naif Boutique Hotel
Exterior
Hotel Posada de Don Rodrigo Antigua

Hotel Posada de Don Rodrigo Antigua

Hotel Posada de Don Rodrigo Antigua
3.5 star property
29 km from Zona 16
9.4 out of 10, Exceptional, (657)
"Friendly staff, clean rooms the location was excellent. "
United States
Elias
The price is ￥25,154
￥34,498 total
includes taxes & fees
Dec 29 - Dec 30
Hotel Posada de Don Rodrigo Antigua
Egyptian cotton sheets, premium bedding, in-room safe, desk
El Convento Boutique Hotel

El Convento Boutique Hotel

El Convento Boutique Hotel
4.0 star property
28.7 km from Zona 16
9.4 out of 10, Exceptional, (808)
"Hotel was in a good location. "
United States
Paige
The price is ￥30,916
￥40,060 total
includes taxes & fees
Jan 12 - Jan 13, 2026
El Convento Boutique Hotel
Exterior
Good Hotel Guatemala City

Good Hotel Guatemala City

Good Hotel Guatemala City
3.0 star property
Zona 4, 4.9 km from Zona 16
9.4 out of 10, Exceptional, (251)
"Really liked this location is great "
United States
Malika
The price is ￥16,107
￥19,651 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Good Hotel Guatemala City
Property amenity
Porta Hotel Antigua

Porta Hotel Antigua

Porta Hotel Antigua
4.5 star property
29.1 km from Zona 16
9.4 out of 10, Exceptional, (1002)
"Everything about this hotel was fantastic. The bed was so comfortable. "
United States
Raymond
The price is ￥27,597
￥35,230 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Porta Hotel Antigua
Lounge
Good Hotel Antigua

Good Hotel Antigua

Good Hotel Antigua
4.0 star property
28.5 km from Zona 16
9.2 out of 10, Wonderful, (527)
"Very friendly staff and the room was as expected, clean and cozy. "
United States
Sayda
The price is ￥29,048
￥35,439 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Good Hotel Antigua
5 Junior Suite Santa Catalina | Premium bedding, down comforters, pillowtop beds, in-room safe
San Rafael Hotel

San Rafael Hotel

San Rafael Hotel
4.0 star property
29 km from Zona 16
9.8 out of 10, Exceptional, (442)
"Helpful and courteous staff, clean room, excellent location and beautiful common areas. Super quiet and peaceful. "
United States
Ricardo
The price is ￥29,042
￥36,380 total
includes taxes & fees
Dec 29 - Dec 30
San Rafael Hotel
In-room safe, desk, soundproofing, iron/ironing board
Adriatika Hotel & Residence

Adriatika Hotel & Residence

Adriatika Hotel & Residence
4.5 star property
Zona 14, 6.9 km from Zona 16
9.4 out of 10, Exceptional, (956)
"Great hotel close to the airport. "
United States
Itzhak
The price is ￥14,756
￥18,003 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Adriatika Hotel & Residence
Fitness studio
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo
4.5 star property
28.4 km from Zona 16
9.2 out of 10, Wonderful, (1019)
"Great room, the food was awesome and the amenities are just amazing."
United States
Cesar Luis Sinclair
The price is ￥37,161
￥47,241 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hotel Museo Spa Casa Santo Domingo
Front of property
La Inmaculada Hotel

La Inmaculada Hotel

La Inmaculada Hotel
3.5 star property
Zona 10, 4.5 km from Zona 16
9.2 out of 10, Wonderful, (611)
"Everything was perfect, the room was perfectly cleaned every day, the restaurant is amazing, the people that wirks there amazing!!"
United States
Claudia
La Inmaculada Hotel
Property grounds
Casa Santa Rosa Hotel Boutique

Casa Santa Rosa Hotel Boutique

Casa Santa Rosa Hotel Boutique
3.5 star property
28.6 km from Zona 16
9.6 out of 10, Exceptional, (322)
"Best place to stay in Antigua!!"
United States
Maria
The price is ￥24,421
￥29,793 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Casa Santa Rosa Hotel Boutique
Interior entrance
Tikal Futura Hotel & Convention Center

Tikal Futura Hotel & Convention Center

Tikal Futura Hotel & Convention Center
4.5 star property
Zona 11, 9.1 km from Zona 16
9.0 out of 10, Wonderful, (1005)
"Great place to stay and relax. Beautiful rooms and great staff"
United States
Tracy
The price is ￥16,738
￥20,421 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Tikal Futura Hotel & Convention Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Zona 16

Find the best Zona 16 areas and neighborhoods for the activities you enjoy most.

Zona 10

Zona 10 is known for its ample dining options, and you can make a stop by Oakland Mall and Plaza Fontabella Shopping Center while in the area.

Zona 1

Zona 1 is noteworthy for its historic sites, and you can make a stop at top attractions like Constitution Square and Guatemala City Hall.

Zona 13

Zona 13 is noteworthy for its gardens, and you can make a stop at top attractions like Avenida Las Américas and El Obelisco.

Zona 9

Zona 9 is known for its abundant dining options, and you can plan a trip to Avenida La Reforma and Torre del Reformador while you're in town.

Zona 4

Visitors to Zona 4 enjoy its restaurants, and if you want to do some exploring, Avenida La Reforma is worth a stop.

Top Zona 16 Hotel Reviews

Barceló Guatemala City

Barceló Guatemala City

10/10 Excellent
"Nice room nice pool nice gym. Premier suite was worthwhile"
martin 1-night trip
Posted 1 day ago
Barceló Guatemala City

Frequently asked questions

What is Zona 16 like?
Zona 16 is a neighborhood that travelers like for its festivals. Are you looking for Zona 16 travel tips? Be sure to check out Paseo Cayala and Kanajuyú Ecological Park while you're in the neighborhood.
What's the best accommodation in Zona 16?
Based on our traveler data, AC Hotel by Marriott Guatemala City is one of the top choices for your stay in Zona 16. This hotel is steps from Paseo Cayala, and offers a restaurant and free parking. Another good choice for your stay in the area is Cayalá Lofts.
How many hotels can I expect to find in Zona 16?
Expedia has 46 hotels and other accommodations in Zona 16 to choose from, making this an ideal home base for exploring the greater Guatemala City area.
If I need to cancel my hotel reservation in Zona 16, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to view the best deals in Zona 16.
Where can I learn more about changing or cancelling my trip to Zona 16?
For additional details about changing or cancelling your trip to Zona 16, click here.
What is there to do in this Guatemala City neighborhood?
A few attractions you might want to check out while you're in Zona 16 are Paseo Cayala and Kanajuyú Ecological Park. When you're sightseeing in Guatemala City, Embassy of the United States of America and Popol Vuh Museum are also worth a stop.

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