Find hotels in Vandalia, MO from ¥10,439

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Our top choices for Vandalia hotels

Comfort Inn & Suites - Hannibal

2.5 star property
Hannibal
7.6 out of 10, Good, (659)
"Below average facility. Needs some upgrades and could use a good cleaning. Staff was helpful."
United States
JACQUI
The price is ¥12,580
¥14,915 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Comfort Inn & Suites - Hannibal

Best Western Teal Lake Inn

2.5 star property
Mexico
8.4 out of 10, Very Good, (482)
"It was a great stay and very quiet. The restful sleep was enjoyable."
United States
Eric
The price is ¥14,644
¥16,379 total
includes taxes & fees
Dec 14 - Dec 15
Best Western Teal Lake Inn

Knights Inn New Florence

2.0 star property
New Florence
6.8 out of 10, (533)
"Reasonable hotel."
United States
Kevin
The price is ¥10,562
¥11,985 total
includes taxes & fees
Dec 10 - Dec 11
Knights Inn New Florence

Days Inn by Wyndham Mexico

2.0 star property
Mexico
7.0 out of 10, Good, (296)
"Comfortable bed... Didn't like stool loose on base."
United States
Marvin
The price is ¥11,919
¥13,332 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Days Inn by Wyndham Mexico

Baymont by Wyndham Hannibal

2.5 star property
Hannibal
6.4 out of 10, (735)
" There actually was a pool & there actually was a hot breakfast. It didn't just say there was & not have what was listed. One of the best we've been to as of late. Would stay again if in the area. "
United States
Thomas
The price is ¥10,126
¥11,707 total
includes taxes & fees
Dec 10 - Dec 11
Baymont by Wyndham Hannibal

Cannon Dam Cabins

3.0 star property
Perry
9.2 out of 10, Wonderful, (13)
"Love this place! Great location to the launch ramp and Dog friendly. Management is amazing and kind and knowledgeable of the area. "
United States
stacy
The price is ¥15,952
¥16,969 total
includes taxes & fees
Dec 10 - Dec 11
Cannon Dam Cabins

The Junction Inn

2.0 star property
Perry
6.4 out of 10, (37)
"Clean, affordable, friendly & easy access of hwy & airport/rental car area!"
United States
Staci
The Junction Inn

Kennedys Red Barn Inn

2.5 star property
Perry
9.2 out of 10, Wonderful, (27)
"The hosts were very accommodating and attentive to their guest needs. Wonderful place to stay!"
United States
Jeff
The price is ¥13,538
¥14,401 total
includes taxes & fees
Dec 10 - Dec 11
Kennedys Red Barn Inn

Budget Inn Mexico MO on US 54

2.0 star property
Mexico
7.0 out of 10, Good, (110)
"Great "
United States
Jedrzej
The price is ¥13,203
¥14,769 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Budget Inn Mexico MO on US 54
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Vandalia Hotel Reviews

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Frequently asked questions

Where is the best place to stay in Vandalia?
Located 28.1 mi (45.2 km) from the heart of Vandalia, Knights Inn New Florence is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are Comfort Inn & Suites - Hannibal and Best Western Teal Lake Inn. See all available top hotels, or vacation rentals in Vandalia.
What are some of the best vacation rentals that Vandalia has to offer?
"Peaceful Retreat" @ MTL: This vacation home rental outside of Vandalia is located in a rural location and has a fireplace, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. See all vacation rentals in Vandalia.
If I need to cancel my hotel reservation in Vandalia, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Vandalia.
Where can I learn more about changing or cancelling my trip to Vandalia?
For more information about updating your trip to Vandalia or cancelling it, go to https://www.expedia.com/service/.
What is staying in Vandalia like?
Visitors are sure to enjoy all that Vandalia has to offer. There are 45 hotels and other accommodations in the surrounding area. Find out more about Vandalia.
What are the top places to visit in Vandalia?
Places to visit in the wider area include South Fork Recreation Area, Bill Trower Memorial Park, and Perry Park. Additionally, you'll find Robert E Allen Recreation Area in the area. Check out what more to see and do in Expedia's Vandalia guide.
What's the weather like in Vandalia?
The hottest months are usually July and August with an average temp of 74°F, while the coldest months are January and February with an average of 35°F. Average annual precipitation for Vandalia is 49 inches.

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