Search Vacation Homes in Upstate South Carolina

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Upstate South Carolina vacation homes

The Blue Bungalow by Unity Park - Newly Renovated

The Blue Bungalow by Unity Park - Newly Renovated
Woodside Cotton Mill Village Historic District
9.8 out of 10, Exceptional, (85 reviews)
"The house was super clean and nice! The host was awesome. We thoroughly enjoyed our stay. Convenient to everything. We will definitely stay again!"
United States
Lisa
The price is ¥11,491
¥34,563 total
includes taxes & fees
Feb 2 - Feb 3
The Blue Bungalow by Unity Park - Newly Renovated

Welcome To Downtown Pickens close to Clemson and Lake Keowee

Welcome To Downtown Pickens close to Clemson and Lake Keowee
Pickens
9.8 out of 10, Exceptional, (31 reviews)
"Great location, close to great restaurants and downtown. Beautiful area!"
United States
Tom B.
The price is ¥16,816
¥40,615 total
includes taxes & fees
Feb 1 - Feb 2
Welcome To Downtown Pickens close to Clemson and Lake Keowee

Cozy 2BR Near Furman & Downtown, Fenced Yard

Cozy 2BR Near Furman & Downtown, Fenced Yard
Greenville
10.0 out of 10, Exceptional, (2 reviews)
"delightful house on a very mellow street. super easy access to downtown, a grocery store close, beautiful backyard for the dog, lovely kitchen. i was in town for my anniversary week and my partner and i enjoyed the stay very much. hosts were helpful and communicative, the house was exactly as described and we literally had zero issues. i have no problem recommending this house strongly! "
United States
jon b.
The price is ¥14,729
¥36,069 total
includes taxes & fees
Feb 11 - Feb 12
Cozy 2BR Near Furman & Downtown, Fenced Yard

Pet-Friendly Cabin in Marietta w/ Porch Swings

Pet-Friendly Cabin in Marietta w/ Porch Swings
Cleveland
10.0 out of 10, Exceptional, (1 review)
"Accurate listing, easy to find! "
United States
Beth T.
The price is ¥12,845
¥39,993 total
includes taxes & fees
Feb 9 - Feb 10
Pet-Friendly Cabin in Marietta w/ Porch Swings

Private family, pet friendly with fenced yard near Limestone College and Outlets

Private family, pet friendly with fenced yard near Limestone College and Outlets
Gaffney
9.8 out of 10, Exceptional, (26 reviews)
"It is a really nice place and in a quiet area. Very cute backyard. Would stay again!! "
United States
Jessica S.
The price is ¥12,456
¥31,738 total
includes taxes & fees
Jan 30 - Jan 31
Private family, pet friendly with fenced yard near Limestone College and Outlets

Secluded Yurt Hideaway 10 min to Table Rock

Secluded Yurt Hideaway 10 min to Table Rock
cleveland
9.6 out of 10, Exceptional, (7 reviews)
"The place is awesome! I don’t usually leave comments but this place is worth the visit."
United States
Michael
The price is ¥14,558
¥51,297 total
includes taxes & fees
Feb 10 - Feb 11
Secluded Yurt Hideaway 10 min to Table Rock

Country Apple Cottage

Country Apple Cottage
Pickens
10.0 out of 10, Exceptional, (31 reviews)
"Great place close to Clemson. "
United States
Carlos V.
The price is ¥12,472
¥25,942 total
includes taxes & fees
Feb 2 - Feb 3
Country Apple Cottage

Lake Hartwell Frank Howard Home Clemson

Lake Hartwell Frank Howard Home Clemson
4.0 star property
Anderson
The price is ¥19,151
¥47,182 total
includes taxes & fees
Feb 1 - Feb 2
Lake Hartwell Frank Howard Home Clemson

Hobbit Hideaway - Do Something Different!

Hobbit Hideaway - Do Something Different!
Marietta
10.0 out of 10, Exceptional, (51 reviews)
"Very well appointed."
United States
Sara P.
The price is ¥10,510
¥24,408 total
includes taxes & fees
Jan 27 - Jan 28
Hobbit Hideaway - Do Something Different!

Family-Friendly 3/2 Home Near Prisma, Fenced Yard

Family-Friendly 3/2 Home Near Prisma, Fenced Yard
Greenville
10.0 out of 10, Exceptional, (5 reviews)
"Great location and accommodations."
United States
Susan B B.
The price is ¥15,414
¥47,099 total
includes taxes & fees
Feb 10 - Feb 11
Family-Friendly 3/2 Home Near Prisma, Fenced Yard

Craftsman Style Brick Cottage 1937 downstairs apartment

Craftsman Style Brick Cottage 1937 downstairs apartment
Tryon
10.0 out of 10, Exceptional, (35 reviews)
"Great property!"
United States
Scott C.
The price is ¥17,516
¥37,657 total
includes taxes & fees
Jan 27 - Jan 28
Craftsman Style Brick Cottage 1937 downstairs apartment

Downtown Easley Home

Downtown Easley Home
Easley
8.0 out of 10, Very Good, (7 reviews)
"The house was great for our one night stay. The house was clean and stocked. We had to leave early and didn't spend the entire night. But the host was gracious and easy to communicate with. Would recommend!"
United States
CANDY B.
The price is ¥16,675
¥40,287 total
includes taxes & fees
Jan 30 - Jan 31
Downtown Easley Home

Sleek 3BR Pet-Friendly Oasis, Close to City

Sleek 3BR Pet-Friendly Oasis, Close to City
Taylors
10.0 out of 10, Exceptional, (5 reviews)
"Very clean. Wonderful location and private. "
United States
Paula
The price is ¥16,442
¥46,517 total
includes taxes & fees
Jan 27 - Jan 28
Sleek 3BR Pet-Friendly Oasis, Close to City

Lake Keowee Resort -Pools, Golf, Boat, Pickleball, Dog Friendly

Lake Keowee Resort -Pools, Golf, Boat, Pickleball, Dog Friendly
Salem
9.8 out of 10, Exceptional, (48 reviews)
"Great accommodations and very convenient to Clemson"
United States
Lanse M.
The price is ¥17,906
¥86,149 total
includes taxes & fees
Feb 7 - Feb 8
Lake Keowee Resort -Pools, Golf, Boat, Pickleball, Dog Friendly

⭐️Hot Tub⭐️ Luxury Getaway Near GSP Airport Downtown Greer Greenville Spartanburg

⭐️Hot Tub⭐️ Luxury Getaway Near GSP Airport Downtown Greer Greenville Spartanburg
Lyman
10.0 out of 10, Exceptional, (41 reviews)
"2nd time staying, great place."
United States
DAWN M.
The price is ¥14,013
¥32,491 total
includes taxes & fees
Feb 2 - Feb 3
⭐️Hot Tub⭐️ Luxury Getaway Near GSP Airport Downtown Greer Greenville Spartanburg

Skyline Split B Retreat Close to Everything You Need! Quiet, Clean & Convenient.

Skyline Split B Retreat Close to Everything You Need! Quiet, Clean & Convenient.
Woodside Cotton Mill Village Historic District
10.0 out of 10, Exceptional, (3 reviews)
"It was such a comfy little house and check in was very convenient and it’s close to a lot of things."
United States
lisa E.
The price is ¥10,432
¥29,459 total
includes taxes & fees
Jan 27 - Jan 28
Skyline Split B Retreat Close to Everything You Need! Quiet, Clean & Convenient.

Pet-Friendly Greer Home: Near Airport & Downtown

Pet-Friendly Greer Home: Near Airport & Downtown
Greer
10.0 out of 10, Exceptional, (3 reviews)
"Very clean and spacious house with everything we needed. Great location near restaurants and grocery store. House was way better than the photos depicted. Will definitely stay again. Nice touches such as water bottles in refrigerator, nice supply of kuerig coffee pods, and snacks on the counter. Couldn’t have been better! "
United States
Andrea B.
The price is ¥19,696
¥51,509 total
includes taxes & fees
Feb 8 - Feb 9
Pet-Friendly Greer Home: Near Airport & Downtown

Cozy Bamboo Retreat, Modern Comforts Duplex

Cozy Bamboo Retreat, Modern Comforts Duplex
Wellford
9.8 out of 10, Exceptional, (8 reviews)
"Clean, comfortable, and very quiet. Very pet friendly We were here for a short stay. "
United States
JR (Arthur) F.
The price is ¥15,534
¥46,797 total
includes taxes & fees
Jan 27 - Jan 28
Cozy Bamboo Retreat, Modern Comforts Duplex

~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~

~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~
Spartanburg
10.0 out of 10, Exceptional, (49 reviews)
"Home was clean and the hosts communication was wonderful!!! "
United States
Jeremy R.
The price is ¥15,103
¥32,664 total
includes taxes & fees
Feb 8 - Feb 9
~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~

Cozy Place - Clean - Workspace with Wifi

Cozy Place - Clean - Workspace with Wifi
Boiling Springs
8.8 out of 10, Excellent, (6 reviews)
"Nice 2BR/1 Bath home that is near to just about everything in Spartanburg. This home is appointed with an L shaped love seat/lounger, a rocker, and a huge tv in the living room, a 6 seat dinette, well equipped kitchen with washer and dryer, full bathroom, and 2 bedrooms with queen beds. Check in/out was a breeze. Communication with the owner was quick and easy. There were only a few minor hiccups at the home but the owner answered within minutes and addressed them all. "
United States
Lisa M.
The price is ¥17,454
¥45,816 total
includes taxes & fees
Feb 17 - Feb 18
Cozy Place - Clean - Workspace with Wifi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Upstate South Carolina Hotel Reviews

Find out more about Upstate South Carolina

Upstate South Carolina Vacation Homes information

Number of reviews
434
Accommodation
856 Vacation Homes
Lowest Price
¥24,408
Highest Price
¥86,149

Explore a world of travel with Expedia