Top 10 Hotels in Upstate South Carolina, SC from ￥12,218 - Competitive Prices

A bench, a bicycle, and a lake surrounded by trees.

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Go beyond your typical stay in Upstate South Carolina

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Our top choices for Upstate South Carolina hotels

An outdoor seating area with sofas, a fire pit, and string lights.

A modern lounge area with seating arrangements, a large window offering a view of the outdoors, and contemporary lighting fixtures.

A modern hotel with a multi-story structure, large windows, and a prominent vertical light strip.

A modern interior with hanging chairs, tables, and a view of the parking lot.

1. Tru by Hilton Spartanburg

Spartanburg

Anthony

￥16,653

￥18,486 total

includes taxes & fees

Nov 1 - Nov 2

A modern hotel lobby with a fireplace, comfortable seating, and a large window.

A modern hotel lobby with a large seating area, a reception desk, and a view of the outdoors.

A modern hotel room with a large mirror, a sink, a microwave, and a compact kitchenette. There is a seating area with a chair and a sofa, and a large window with curtains.

A Hampton Inn & Suites hotel with a modern facade, a covered entrance, and a brick pillar.

2. Hampton Inn & Suites Greenville Airport, SC

Greenville

Tina

￥15,421

￥17,472 total

includes taxes & fees

Nov 1 - Nov 2

A modern hotel lobby with a long reception desk, bar area with stools, seating with patterned cushions, and a large window offering a view of greenery.

An indoor swimming pool with clear water, a blue border, and a lifeguard station. There are lounge chairs and a covered seating area.

A vending area with various snack and drink options, including chips, sodas, and bottled water.

A hotel room with a kitchenette, two beds, a red sofa, and a dining area.

3. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Spartanburg

Amy

￥16,119

￥17,892 total

includes taxes & fees

Oct 31 - Nov 1

A modern lobby with a reception desk, seating area, and a television screen.

A hotel room with two beds, a desk with a lamp, a chair, a patterned rug, and a large window.

A hotel with a covered entrance, brick exterior, and a sign indicating it is a Best Western hotel.

A modern restaurant with high tables and chairs, a counter with a coffee machine, and a patterned wall.

4. Best Western Spartanburg I-26

Spartanburg

Santhosh

￥15,924

￥17,676 total

includes taxes & fees

Oct 8 - Oct 9

A multi-level hotel atrium with a central open area, multiple balconies, and a variety of seating arrangements.

An indoor swimming pool with lounge chairs and potted plants.

An outdoor patio with a stone fire pit, wicker chairs, and a pergola structure.

A large hotel with a central courtyard, surrounded by manicured lawns and trees.

5. Embassy Suites Greenville Golf Resort & Conference Center

Greenville

Ethan

￥16,653

￥18,868 total

includes taxes & fees

Oct 11 - Oct 12

A modern living room with a fireplace, a flat-screen TV, and a dining area with chairs and a table.

A modern kitchen with a central island, bar stools, and pendant lighting.

A hotel with a modern design, featuring a prominent entrance and a parking area.

A hotel room with a bed, a desk, a chair, a sofa, and a TV.

6. Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan

Duncan

Joseph

￥18,734

￥21,075 total

includes taxes & fees

Oct 4 - Oct 5

A modern interior with a fireplace, seating, and a wooden wall.

A reception desk with a 'Welcome to Hampton' sign and a cityscape photograph.

A hotel room with a flat-screen TV, a desk with a chair, a bed, and framed pictures on the wall.

A modern interior with seating areas, tables, a flat-screen TV, and a fireplace.

7. Hampton Inn & Suites Greenville/Spartanburg I-85, SC

Duncan

Kathy

￥15,656

￥17,379 total

includes taxes & fees

Oct 26 - Oct 27

A modern restaurant interior with round tables and chairs, a kitchen area, and large windows offering a view of parked cars outside.

A reception area with a stone counter, a laptop, and a sign indicating a Chairman's Award.

A pool area with lounge chairs and a sign for Best Western Plus.

A modern kitchen with a central island, three bar stools, pendant lighting, and a decorative flower arrangement.

8. Best Western Plus Greenville I-385 Inn & Suites

Greenville

Stephanie

￥11,965

￥13,161 total

includes taxes & fees

Oct 18 - Oct 19

An aerial view of a sports complex with multiple sports fields, a large parking area, and a stadium.

A hotel room with a sectional sofa, a bed, a desk, and a large window.

A modern building with a glass facade and a brick base, featuring a prominent entrance with a flag.

A large sports complex with multiple fields and tall light poles.

9. Comfort Suites Greenville Airport

Greenville

Ryan

￥14,036

￥15,903 total

includes taxes & fees

Nov 1 - Nov 2

A modern kitchen with hanging light fixtures and bar seating.

A modern hotel room with a large desk, a comfortable sofa, and a bed.

A hotel patio with outdoor seating, stone pillars, and a modern building in the background.

A modern bar area with a central island, bar stools, and overhead lighting.

10. DoubleTree by Hilton Greenville Woodruff Road

Greenville

Jeffery

￥18,012

￥20,405 total

includes taxes & fees

Nov 1 - Nov 2

A bar area with multiple hanging decorative lights, a counter with bar stools, and a seating area with chairs.

A spacious indoor venue with rows of white chairs adorned with purple sashes, large windows, and a modern ceiling design.

A banquet hall with round tables set for dining, large windows, and a stage with curtains.

A well-furnished living room with a chandelier, wooden furniture, and a view through a window.

11. Greenville Marriott

Greenville

John

￥19,206

￥21,759 total

includes taxes & fees

Oct 25 - Oct 26

A modern lobby with a fireplace, comfortable seating, and a flat-screen TV.

An outdoor seating area with wicker furniture and red cushions, surrounded by a stone fire pit.

A modern bar area with a counter, stools, and a menu board.

A modern hotel lobby with a bar area, seating arrangements, and a visible menu board.

12. Courtyard Greenville-Spartanburg by Marriott

Greer

Evan

￥15,313

￥17,350 total

includes taxes & fees

Oct 18 - Oct 19

A modern kitchen with a central island, equipped with a microwave, toaster, and coffee machine.

A modern lobby with blue sofas, a reception desk, and a glass coffee table.

A hotel room with a bed, a gray sofa, two ottomans, a window with a view, and abstract artwork on the wall.

A hotel room with a desk, office chair, sofa, and a large wall art piece.

13. Comfort Suites At WestGate Mall

Spartanburg

tara

￥14,244

￥15,811 total

includes taxes & fees

Nov 1 - Nov 2

An indoor swimming pool with a clear blue water, surrounded by lounge chairs and a tiled floor.

A spacious indoor seating area with tables and chairs, large windows with blinds, and a potted plant.

A spacious indoor area with a seating area, a counter with a coffee machine, and a refrigerator.

A Holiday Inn Express & Suites building with a covered entrance, stone pillars, and a parking area.

14. Holiday Inn Express & Suites Greenville Airport by IHG

Greer

Stacie

￥15,271

￥16,799 total

includes taxes & fees

Oct 25 - Oct 26

A modern hotel lobby with a bar area, seating, and a patterned floor.

A hotel room with two beds, a desk, a TV, and a large window with curtains.

A hotel entrance with a welcoming sign, a covered walkway, and a landscaped area with benches and flowers.

A modern living room with a sofa, armchairs, a coffee table, and a patterned rug.

15. Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Greenville

George

￥14,381

￥16,294 total

includes taxes & fees

Nov 1 - Nov 2

A rooftop bar with seating, a bar area, and a view of the cityscape at dusk.

A swimming pool with steps leading up to a building entrance, surrounded by lounge chairs and umbrellas.

A modern restaurant with a bar area, high ceilings, and a view of the cityscape.

A spacious living area with a modern sofa, armchairs, a coffee table, and a dining area with chairs and a table.

16. AC Hotel by Marriott Spartanburg

Spartanburg

Willow

￥26,606

￥29,533 total

includes taxes & fees

Oct 25 - Oct 26

A large indoor swimming pool with clear water, surrounded by lounge chairs and tables, and equipped with safety signage.

A hotel lobby with a reception desk, seating area, and large windows.

A modern hotel with a well-maintained lawn, brick pathway, and a row of white flowers.

17. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Spartanburg

Bogdan

￥17,298

￥19,201 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lobby with a reception desk, green seating area, and multiple tables and chairs.

A vending machine area with snacks and beverages, and a display of green apples.

An outdoor patio area with brick walls, a fire pit, and several chairs and tables.

A modern lounge area with a green sofa, multiple tables, chairs, and a flat-screen TV.

18. Home2 Suites by Hilton Duncan

Duncan

Marina

￥19,269

￥21,389 total

includes taxes & fees

Oct 25 - Oct 26

A modern kitchen with a large wooden table and brown leather chairs, a microwave, and a coffee machine.

A compact kitchen with white cabinets, a microwave, a sink, and a flat-screen TV.

A reception area with a modern design, featuring a reception desk, seating area, and a view through the glass doors.

19. Extended Stay America Premier Suites - Greenville - Spartanburg - I-85

Duncan

Tenisha

￥16,292

￥18,082 total

includes taxes & fees

Oct 3 - Oct 4

A modern living room with a fireplace, two sofas, and a coffee table.

A hotel room with two beds, a desk, a TV, and a window with curtains.

A hotel lobby with multiple seating areas, a reception desk, and a fireplace.

A modern gym with various exercise equipment, motivational wall graphics, and a large window offering a view of the outdoors.

20. Best Western Spartanburg Northwest

Spartanburg

Muhammad Awais

￥14,586

￥16,513 total

includes taxes & fees

Nov 1 - Nov 2

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Vacation Rentals in Upstate South Carolina

Aparthotel

A modern hotel with a sign reading "apt suites" and a parking lot with cars.

An outdoor patio with a stone barbecue grill and white Adirondack chairs.

stayAPT Suites Greenville-Haywood Mall

Greenville

"Everything was great"

Cottage

A living room with a sofa, a dining table, chairs, a kitchen area, and a view through large windows.

A cozy living room with a sofa, two side tables, a coffee table, and a patterned rug.

A blue house with a wooden deck, a red door, and a fenced backyard with a small garden.

A two-story house with a front porch, a small garden, and a wooden fence.

Greer Guest House < 1 Mi to Park & Downtown Area!

Greer

"Nice place en Greenville area "

Cabin

A swimming pool with lounge chairs and a covered area with tables and chairs.

A spacious living room with a dark leather sofa, a wooden coffee table, and a dining area with a table and chairs. Large windows provide natural light and views of the outdoors.

A covered porch with a welcome mat, two black Adirondack chairs, and a bench.

Carolina Camp Cedar

Pickens

"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"

Cabin

A cabin in a forest with a small deck and outdoor seating area.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

"Me and my family had a great time"

Aparthotel

A modern building with outdoor seating and a garden.

A modern kitchen with white cabinetry, a wooden dining table, and a black chair. There is a window with a view of greenery outside.

A modern living room with a sofa, coffee table, and dining table. There is a TV mounted on the wall, a coffee machine, and a bookshelf.

A row of modern, two-story buildings with a covered patio area.

The Station by Compo Hotels

Travelers Rest

"Lovely place to stay. Very clean and well appointed. The host was responsive and welcoming. Comfortable bed and quiet. Highly recommend."

Apartment

A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a granite countertop. There are three white bar stools and two pendant lights.

A modern kitchen with granite countertops, double sinks, and a built-in dishwasher.

A bedroom with a bed, bedside tables, a ceiling fan, and two windows with blinds.

Mint House Greenville Downtown by Kasa

Greenville Downtown

"Excellent location for our trip. Very clean, had everything we needed."

Cottage

A cozy living room with a fireplace, a dining area with a table and chairs, and a large wooden door.

A room with wooden sliding doors, a small black table with a potted plant, and a circular sign with the words "stay awhile".

A cozy living room with a dining table, sofas, and a chandelier.

Clemson Memorabilia House

Clemson

"We enjoyed our stay, it was the perfect size for our family of four. "

Mobile Home

A wooden dining table with green placemats, surrounded by chairs, in a cabin with large windows and wooden walls.

A cozy cabin interior with wooden walls, a loft bedroom, a dining area, and a sofa with cushions.

A rustic cabin with a porch, wooden steps, and a picnic table.

A wooden interior with a loft bed, a green chair, a wooden table, and a map on the wall.

Carolina Landing RV Resort - Caravan Park

Fair Play

"Very nice stay with friendly staff"

Cottage

A living room with a blue sofa, a round coffee table with a vase of flowers, a patterned rug, and a chair. There are paintings on the walls and a window with curtains.

A bed with a white quilted cover, flanked by two wall-mounted nightstands with lamps.

A compact living space with a sofa, a small round table, a wicker chair, a kitchen area with a microwave and cabinets, and a TV mounted on the wall.

A dining area with a wooden table set for two, a blue chair, a small table with a lamp, and a kitchen in the background.

Claires Cottage ~ 4 Mi to Downtown Greenville!

Greenville

"Great trip. The small cottage was perfect for my wife and I and the owner was very responsive."

Cottage

A spacious living room with a dining area, a leather sofa, a TV, and artwork on the walls.

A spacious living room with a brown leather sofa, a white shag rug, and a dining area with a table and chairs.

A white door with a brass knocker, a white bench, a potted plant, and a wicker basket outside a house with a brick foundation and a window with blinds.

A bedroom with a bed, a chair, a nightstand, and a window with curtains.

Families Welcome, Fenced Yard: Inviting Greer Home

Greer

"This property is such an amazing find. Three large bedrooms, very clean and well maintained. Close to town of Greer and all amenities. Very easy check-in. Beds very comfortable. Kitchen well equipped for the week we were there."

Cottage

A living room with a sofa, coffee table, and a dining area with chairs and a table.

A living room with a fireplace, a round wooden table with chairs, a sofa, and a television.

A modern kitchen with white cabinets, stainless steel appliances, and a patterned rug.

A bedroom with a bed, bedside tables, a round mirror, and a ceiling fan.

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Greer

"Very cute home close to everything. Super clean and spacious. Well furnished."

Apartment

A large house with a spacious driveway and a pond in the background.

A kitchen with wooden cabinets, stainless steel appliances, a granite countertop, and a bar stool.

A spacious living room with a high ceiling, a large leather sofa, a flat-screen TV, and a wooden coffee table.

Serene Travelers Rest Apartment: 7 Mi to Downtown!

Travelers Rest

"The best time ever. My wife and I enjoyed our Honeymoon and stay here. We will come back every year for our Anniversary now and also to vacation here. The area was beautiful, quiet, and safe. We had everything we needed. No other vacation spot in South Carolina can compete. Thank you for our wonderful stay and perfect memories! "

Cottage

A house with a grey siding exterior, a white front door, and a window with a white frame.

A living room with a striped sofa, a patterned armchair, and a dark sofa with a floral pillow. There is a wooden coffee table with a book and a plant. A lamp is on a side table next to the sofa.

A dining area with a round table and six chairs, a kitchen with white cabinets, and a window with blinds.

A living room with a brown sofa, a wooden coffee table, a fireplace, a television mounted above the fireplace, and a window with blinds.

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

Greenville

"Amazing place. Great host. "

Cottage

A modern living room with a ceiling fan, a sofa, a chair, and a coffee table. There is a kitchen in the background with cabinets and a countertop.

A modern kitchen with white cabinets, stainless steel appliances, and a marble countertop.

A single-story house with a porch, a gravel driveway, and a well-maintained lawn.

A wooden bridge leading to a playground with green grass and trees.

< 3 Mi to Dtwn: Modern Cottage in Greenville!

Greenville

Cottage

A wooden deck with a bench and a welcome mat, overlooking a well-maintained lawn and trees.

A bedroom with a large bed, a ceiling fan, a TV, and a window with blinds.

A rustic cabin with a wooden deck, a covered patio, and a large window overlooking a wooded area.

A spacious living room with hardwood floors, a fireplace, a sofa, a coffee table, and a television.

Serene Cabin w/ Pond & Creek on South Saluda River

Cleveland

"I chose this cabin due to its close proximity to the pretty place chapel. The property was BEAUTIFUL and tucked away. The silence and change of scenery was well needed and felt like we were at home. I honestly don’t have enough good things to say about the host Mr. Steve and his generosity and professionalism!"

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Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.

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A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Falls Park on the Reedy

9.6/10 (2,661 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

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A wooden cross with inscriptions, set against a mountainous landscape with a cloudy sky.

Fred W. Symmes Chapel

9.8/10 (29 reviews)

You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area.

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Bon Secours Wellness Arena

8.6/10 (1,219 reviews)

Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.

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Memorial Stadium

9.6/10 (410 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game.

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BMW Performance Center

9.0/10 (90 reviews)

You can spend an afternoon browsing the exhibits at BMW Performance Center during your travels in Greer. While in this family-friendly area, you can savor the charming coffeehouses.

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Greenville Convention Center

8.4/10 (571 reviews)

Learn about the events happening at Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.

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Learn more about Upstate South Carolina

Venture to sights like Discovery Island Water Park and Heritage Park as you discover Upstate South Carolina.

See all hotels in Upstate South Carolina

A multi-tiered waterfall cascading over rocks in a forested area.

Top Upstate South Carolina Hotel Reviews

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

10/10 Excellent

"Very nice stay and conviennent"

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

10/10 Excellent

"Really a great stay ."

Lakeside Lodge Clemson

10/10 Excellent

"My first time here. Lovely resort. Pool was awesome. Poolside restaurant had good sandwiches. I wish the breakfast was open before 10:00 am, but the free coffee was nice. I walked to Starbucks for breakfast. Room was spacious."

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

10/10 Excellent

"clean room"

Grand Bohemian Lodge Greenville, Autograph Collection

10/10 Excellent

"The room was very clean and comfortable. Staff was helpful and friendly. The lobby is to die for with the displays of Native American art and jewelry. A fun place e to stay with convenient location."

Comfort Inn & Suites Clemson - University Area

8/10 Good

"Great stay. Clean and conveniently located."

More cheap stays in Upstate South Carolina

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

1024 Woodruff Rd Greenville SC

￥11,107

￥12,218 total

Oct 26 - Oct 27

includes taxes & fees

8.4/10 Very Good! (1,001 reviews)

Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC

￥11,965

￥13,161 total

Oct 18 - Oct 19

includes taxes & fees

Comfort Inn Greenville - Haywood Mall

246 Congaree Road Greenville SC

￥13,460

￥15,278 total

Oct 25 - Oct 26

includes taxes & fees

8.2/10 Very Good! (1,003 reviews)

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC

￥15,924

￥17,676 total

Oct 4 - Oct 5

includes taxes & fees

Comfort Inn & Suites Clemson - University Area

1305 Tiger Blvd Clemson SC

￥17,194

￥19,086 total

Nov 1 - Nov 2

includes taxes & fees

Lakeside Lodge Clemson

13500 Clemson Blvd Seneca SC

￥16,603

￥20,658 total

Oct 4 - Oct 5

includes taxes & fees

9/10 Wonderful! (1,001 reviews)

Hotels in Upstate South Carolina with star-rating

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Find hotels in Upstate South Carolina, SC from ￥12,218

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Upstate South Carolina

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Upstate South Carolina hotels

1. Tru by Hilton Spartanburg

2. Hampton Inn & Suites Greenville Airport, SC

3. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

4. Best Western Spartanburg I-26

5. Embassy Suites Greenville Golf Resort & Conference Center

6. Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan

7. Hampton Inn & Suites Greenville/Spartanburg I-85, SC

8. Best Western Plus Greenville I-385 Inn & Suites

9. Comfort Suites Greenville Airport

10. DoubleTree by Hilton Greenville Woodruff Road

11. Greenville Marriott

12. Courtyard Greenville-Spartanburg by Marriott

13. Comfort Suites At WestGate Mall

14. Holiday Inn Express & Suites Greenville Airport by IHG

15. Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

16. AC Hotel by Marriott Spartanburg

17. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

18. Home2 Suites by Hilton Duncan

19. Extended Stay America Premier Suites - Greenville - Spartanburg - I-85

20. Best Western Spartanburg Northwest

Vacation Rentals in Upstate South Carolina

stayAPT Suites Greenville-Haywood Mall

Greer Guest House < 1 Mi to Park & Downtown Area!

Carolina Camp Cedar

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

The Station by Compo Hotels

Mint House Greenville Downtown by Kasa

Clemson Memorabilia House

Carolina Landing RV Resort - Caravan Park

Claires Cottage ~ 4 Mi to Downtown Greenville!

Families Welcome, Fenced Yard: Inviting Greer Home

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Serene Travelers Rest Apartment: 7 Mi to Downtown!

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

< 3 Mi to Dtwn: Modern Cottage in Greenville!

Serene Cabin w/ Pond & Creek on South Saluda River

Stay near popular Upstate South Carolina attractions

Clemson University

Falls Park on the Reedy

Fred W. Symmes Chapel

Bon Secours Wellness Arena

Memorial Stadium

BMW Performance Center

Greenville Convention Center

Learn more about Upstate South Carolina

Top Upstate South Carolina Hotel Reviews

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Lakeside Lodge Clemson

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Grand Bohemian Lodge Greenville, Autograph Collection

Comfort Inn & Suites Clemson - University Area

More cheap stays in Upstate South Carolina

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Best Western Plus Greenville I-385 Inn & Suites

Comfort Inn Greenville - Haywood Mall

Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Clemson - University Area

Lakeside Lodge Clemson

Hotels in Upstate South Carolina with star-rating

Explore a world of travel with Expedia

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