Visit Downtown Clayton
Popular places to visit
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
City Museum
This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.
Forest Park
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
Private Tour of St. Louis's Iconic BBQ Joints & Breweries
Best of St. Louis Small Group Tour w/ Arch & River Cruise
St. Louis Premium Driving Tour with Boat Ride & Arch
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
Downtown Clayton Hotel Deals
Clayton Plaza Hotel & Extended Stay
Clean room, good breakfast and good location
Reviewed on Dec 9, 2025
AC Hotel St. Louis Clayton
The staff were very helpful while there! I recommend doing valet instead of self parking so you wouldn’t have to go through any hassle with finding a parking space but overall my stay was great. The bed was really comfy. I would definitely stay there again when visiting St Louis.
Reviewed on Nov 25, 2025
Le Méridien St. Louis Clayton
Small rooms but beautiful lobby.
Reviewed on Oct 27, 2025
The Ritz-Carlton, St. Louis
Absolutely beautiful hotel!!! Highly recommend!
Reviewed on Nov 28, 2025
Hyatt Regency St. Louis at The Arch
Great stay
Reviewed on Dec 10, 2025
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
The staff was great !!!
Reviewed on Dec 7, 2025
Check Downtown Clayton hotel availability
Other neighborhoods around Downtown Clayton
Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
University City
Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like St. Louis Black Repertory Company and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.
Ladue
The restaurants and churches are a few reasons travelers visit Ladue. Though there aren't many top sights in the neighborhood, you can visit Saint Louis Galleria Mall and Bella Vita Wines, a few notable attractions nearby.
Dogtown
If you're looking for some top things to see and do in Dogtown and surrounding area, you can visit St. Louis Zoo and St. Louis Art Museum.
The Hill
If you're looking for some top things to see and do in The Hill and surrounding area, you can visit St. Louis Science Center and Missouri Botanical Gardens and Arboretum.
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Downtown Clayton, MO
- St. Louis Union Station
- Gateway Arch
- St. Louis Zoo
- Busch Stadium
- Washington University in St. Louis
- Barnes Jewish Hospital
- City Museum
- Hollywood Casino Amphitheatre
- Fox Theater
- Route 66 State Park
- Anheuser-Busch Brewery
- Missouri Botanical Gardens and Arboretum
- Magic House - St. Louis Children's Museum
- St. Louis Premium Outlets
- St. Louis Aquarium at Union Station
- Grant's Farm
- St. Louis Science Center
- Cathedral Basilica of St. Louis