Clayton, MO
St. Louis
Popular places to visit
Washington University in St. Louis
Enjoy the collegiate vibe at Washington University in St. Louis during your stay in St. Louis. Amble around the area's lush forest or attend a sporting event.
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
Dome at America’s Center
Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's fascinating museums and great live music.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
Private Tour of St. Louis's Iconic BBQ Joints & Breweries
Best of St. Louis Small Group Tour w/ Arch & River Cruise
Downtown St. Louis Smartphone Guided Audio Walking Tour App
St Louis Self-Guided Driving and Walking Audio Tour
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
Clayton Hotel Deals
Clayton Plaza Hotel & Extended Stay
Considering the price I wasn’t expecting such a nice place, from the entrance, to the easy parking, to the amazing breakfast… everything was so great and I would 1000% consider this place for my future stays in St. Louis! The staff was also very helpful and friendly!
Reviewed on Feb 12, 2026
The Ritz-Carlton, St. Louis
Excellent hotel with various restaurants and expansive lobby area.. staff very attentive.
Reviewed on Feb 6, 2026
Le Méridien St. Louis Clayton
Room was beautiful and clean.
Reviewed on Feb 2, 2026
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Nice
Reviewed on Feb 13, 2026
AC Hotel St. Louis Clayton
My room was spotless and very well put together.
Reviewed on Jan 9, 2026
21C Museum Hotel St Louis
Everything was superlative. Staff, hotel, room, pool.
Reviewed on Feb 11, 2026
Other neighborhoods around Clayton
University City
Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Museum of Transportation and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.
Dogtown
If you're looking for some top things to see and do in Dogtown and surrounding area, you can visit St. Louis Zoo and St. Louis Art Museum.
Ladue
The restaurants and churches are a few reasons travelers visit Ladue. Though there aren't many top sights in the neighborhood, you can visit Saint Louis Galleria Mall and St. Louis Art Museum, a few notable attractions nearby.
The Hill
If you're looking for some top things to see and do in The Hill and surrounding area, you can visit St. Louis Science Center and Missouri Botanical Gardens and Arboretum.
Southwest Garden
Though Southwest Garden might not have many top sights, you can venture to the surrounding area to see attractions like Missouri Botanical Gardens and Arboretum and St. Louis Science Center.
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
