Clayton, MO

St. Louis

The illuminated Gateway Arch at night with a city skyline in the background.
A city skyline with a prominent arch bridge reflecting on the water.
A city skyline with a prominent arch bridge at sunset.
A gazebo with a green roof, surrounded by a pond, with red and green foliage in the background.
A historic building with a courtyard, surrounded by lush green grass and trees.

Stay near popular Clayton attractions

Washington University in St. Louis

8.8/10 (1,777 reviews)
Enjoy the collegiate vibe at Washington University in St. Louis during your stay in St. Louis. Amble around the area's lush forest or attend a sporting event.
See properties

Things to do

Pappy's Smokehouse

Private Tour of St. Louis's Iconic BBQ Joints & Breweries

￥20,590
per adult
Private Tour of St. Louis's Iconic BBQ Joints & Breweries
The Gateway Arch National Park & Museum

StL's Signature "Sights and Bites" - Private Tour in St. Louis

￥27,932
per adult
StL's Signature "Sights and Bites" - Private Tour in St. Louis
St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

￥3,831
per adult
100% of travellers recommend
St. Louis Ghost Tour: Sinister Sins & Shadows
Lemp Haunted Neighborhood Walking Tour

Lemp Haunted Neighborhood Walking Tour

￥3,990
per adult
84% of travellers recommend
Lemp Haunted Neighborhood Walking Tour
Landmarks Downtown-West Walking Tour

Landmarks Downtown-West Walking Tour

￥3,192
per adult
Landmarks Downtown-West Walking Tour
Downtown St. Louis Smartphone Guided Audio Walking Tour App

Downtown St. Louis Smartphone Guided Audio Walking Tour App

￥1,237
per adult
100% of travellers recommend
Downtown St. Louis Smartphone Guided Audio Walking Tour App
See all activities in St. Louis

Clayton Hotel Deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is ￥14,598 per night from Aug 30 to Aug 31
￥14,598
￥17,041 total
Aug 30 - Aug 31
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,338 reviews)
"Very helpful and courteous staff."

Reviewed on Aug 17, 2026

Clayton Plaza Hotel & Extended Stay
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave St. Louis MO
The price is ￥24,241 per night from Aug 23 to Aug 24
￥24,241
￥28,540 total
Aug 23 - Aug 24
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Le Méridien St. Louis Clayton
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

3 out of 5
227 South Central Ave St. Louis MO
The price is ￥20,648 per night from Aug 28 to Aug 29
￥20,648
￥24,105 total
Aug 28 - Aug 29
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park ...
AC Hotel St. Louis Clayton
Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

3 out of 5
216 N Meramec Ave St. Louis MO
The price is ￥20,772 per night from Aug 23 to Aug 24
￥20,772
￥24,457 total
Aug 23 - Aug 24
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, a fitness center, and parking (surcharge). Our guests praise the helpful staff ...
8.8/10 Excellent! (1,004 reviews)
"Everything and every were excellent."

Reviewed on Aug 16, 2026

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
The price is ￥21,365 per night from Aug 28 to Aug 29
￥21,365
￥25,195 total
Aug 28 - Aug 29
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,185 reviews)
"It's located right by the Arch. Easy to walk to restaurants."

Reviewed on Aug 16, 2026

Hyatt Regency St. Louis at The Arch
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
The price is ￥15,913 per night from Sep 2 to Sep 3
￥15,913
￥23,301 total
Sep 2 - Sep 3
includes taxes & fees
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (2,222 reviews)
"Smell of fish in the hall outside room. Otherwise great."

Reviewed on Aug 15, 2026

Hollywood Casino & Hotel St. Louis
See all 1,987 properties in Clayton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Clayton

Find the best Clayton areas and neighborhoods for the activities you enjoy most.
The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

An ornate hall with arched ceilings and intricate patterns.
Photo by Terry Eaves
Open Photo by Terry Eaves

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

A modern building with a brick facade, parked cars, and a flower bed with tulips.

Central West End

The ample dining options and lush forests are just a few popular features of the neighborhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

A historic brick building with arched doorways and a sign that reads "Hot Goods Pen House."

St. Charles Historic District

St. Charles Historic District is known for its abundant dining options, and you can plan a trip to Historic Main Street and Missouri River while you're in town.

Clayton, MO