Find Luxury Hotels in St. Charles, MO

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Our top choices for St. Charles luxury hotels

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
The price is ¥25,464
¥32,415 total
includes taxes & fees
Jul 1 - Jul 2
Ameristar Casino Resort and Spa

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (569 reviews)
  • cleanliness
    Ritz-Carlton elegance defines this St. Louis retreat with indulgent spa services and dining excellence.
The price is ¥79,815
¥93,174 total
includes taxes & fees
Jun 7 - Jun 8
The Ritz-Carlton, St. Louis

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,002 reviews)
  • cleanliness
    Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.
The price is ¥56,782
¥66,395 total
includes taxes & fees
Jun 14 - Jun 15
Four Seasons Hotel St Louis

The Inn at Elijah McLeans

The Inn at Elijah McLeans
4.0 star property
Washington
9.0 out of 10, Wonderful, (142 reviews)
The price is ¥20,654
¥23,517 total
includes taxes & fees
Jun 8 - Jun 9
The Inn at Elijah McLeans

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1,592 reviews)
The price is ¥14,279
¥18,943 total
includes taxes & fees
Jun 8 - Jun 9
River City Casino & Hotel

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,074 reviews)
The price is ¥26,872
¥31,690 total
includes taxes & fees
Jun 19 - Jun 20
Hyatt Regency St. Louis at The Arch

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1,959 reviews)
  • cleanliness
    Boutique retreat blends urban charm with luxury, from rooftop views to Egyptian cotton and rainfall showers.
The price is ¥22,673
¥26,966 total
includes taxes & fees
Jun 21 - Jun 22
Moonrise Hotel

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,201 reviews)
The price is ¥25,432
¥30,247 total
includes taxes & fees
Jun 21 - Jun 22
Live by Loews - St.Louis

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very Good, (1,090 reviews)
The price is ¥23,673
¥27,695 total
includes taxes & fees
Jun 19 - Jun 20
Renaissance St. Louis Airport Hotel

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,331 reviews)
The price is ¥24,869
¥29,575 total
includes taxes & fees
Jun 28 - Jun 29
Embassy Suites by Hilton St. Louis Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top St. Charles Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Charles?
During your visit, you might want to enjoy the casinos and shopping which St. Charles is known for.
What's the best luxury hotel in St. Charles?
Ameristar Casino Resort and Spa is a luxury hotel with 6 restaurants and 2 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay.
When can I expect good weather in St. Charles?
Planning for the weather is an important factor for making your trip to St. Charles a success, especially when you're splurging. The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for St. Charles is 46 inches.
What's there to see and do in St. Charles?
When you're in St. Charles, enjoy exploring the sights and attractions here including Historic Main Street, First Missouri State Capitol Historic Site, and Katy Trail. If you have a little extra time during your trip, you might want to make a stop at Lewis & Clark Boathouse and Nature Center and St Charles Convention Center.