A calm lake reflecting trees with autumn foliage, a clear sky, and a distant shoreline.

Find Luxury Hotels in St. Charles, MO

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on St. Charles Luxury Hotels

Next weekend
Nov 13 - Nov 15
In two weeks
Nov 20 - Nov 22

Our top choices for St. Charles luxury hotels

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

1. Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
St. Charles
9.6 out of 10, Exceptional, (1,006 reviews)
"I enjoyed my stay"
United States
Madhusudhana Rao
The price is ￥22,978
￥26,639 total
includes taxes & fees
Nov 15 - Nov 16
Drury Plaza Hotel St. Louis St. Charles
A brick building with a sign reading "Country Inn & Suites."

2. Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1,112 reviews)
"Very convenient to downtown St Charles. As per previous visits this hotel is excellent for the price range of the rooms."
United States
Stewart
The price is ￥20,105
￥23,106 total
includes taxes & fees
Dec 6 - Dec 7
Country Inn & Suites by Radisson, St. Charles Historic District
A modern kitchen with a central island, breakfast bar, and various appliances.

3. Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area
2.5 star property
St. Charles
9.0 out of 10, Wonderful, (762 reviews)
"Great stay!"
United States
Sara
The price is ￥18,724
￥22,499 total
includes taxes & fees
Nov 22 - Nov 23
Hampton Inn & Suites St. Charles Old Town Area
A multi-level hotel lobby with numerous seating areas, a central water feature, and a variety of plants.

4. Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
St. Charles
8.8 out of 10, Excellent, (1,002 reviews)
"Great place to stay"
United States
Elyse
The price is ￥20,663
￥23,749 total
includes taxes & fees
Nov 22 - Nov 23
Embassy Suites by Hilton St. Louis St. Charles
A modern hotel with a prominent Hilton logo, multiple floors, and a well-lit entrance.

5. Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO
2.5 star property
St. Charles
8.6 out of 10, Excellent, (890 reviews)
"Nice relaxing place"
United States
Michael
The price is ￥20,071
￥23,268 total
includes taxes & fees
Nov 22 - Nov 23
Tru by Hilton St. Charles St. Louis, MO
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

6. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,093 reviews)
"Very nice hotel, lots of amenities, and restaurants"
United States
Carter
The price is ￥25,230
￥32,116 total
includes taxes & fees
Nov 22 - Nov 23
Ameristar Casino Resort and Spa
A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.

7. Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very good, (1,005 reviews)
"Great stay."
United States
Bryan
The price is ￥14,629
￥16,812 total
includes taxes & fees
Nov 22 - Nov 23
Comfort Suites St Charles - St Louis
A spacious living room with a large sectional sofa, a coffee table, and a fireplace. There is a television mounted on the wall and a chandelier hanging from the ceiling.

8. Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel
3.0 star property
St. Charles
8.2 out of 10, Very good, (1,000 reviews)
"Hotel was clean and staff were super friendly. Breakfast was good and coffee bar was excellent!"
United States
Steven
The price is ￥13,336
￥15,461 total
includes taxes & fees
Nov 12 - Nov 13
Best Western Plus The Charles Hotel
Exterior

9. Candlewood Suites St Louis St Charles by IHG

Candlewood Suites St Louis St Charles by IHG
2.5 star property
St. Charles
7.6 out of 10, Good, (830 reviews)
"Only stayed for 6 hours after returning from a trip but the staff who checked me in was awesome and v3ry helpful!!!"
United States
Jeffrey
The price is ￥13,312
￥15,299 total
includes taxes & fees
Nov 29 - Nov 30
Candlewood Suites St Louis St Charles by IHG
A spacious lobby with a reception desk, seating area, and a fireplace.

10. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn
2.5 star property
St. Charles
5.6 out of 10, (1,004 reviews)
"Clean and quiet with very friendly and professional staff."
United States
Gonzalo
The price is ￥15,846
￥18,369 total
includes taxes & fees
Nov 9 - Nov 10
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
A hotel room with a large bed, two bedside tables with lamps, a desk with a chair, a door, and a wall with a road map mural.

11. Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles
2.0 star property
St. Charles
8.2 out of 10, Very good, (1,003 reviews)
"Clean room, staff was polite and helpful!"
United States
Tammie
The price is ￥12,393
￥14,244 total
includes taxes & fees
Dec 6 - Dec 7
Super 8 by Wyndham St Charles
A swimming pool area with red and white lounge chairs, a glass table, and a blue and yellow ceiling.

12. Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.2 out of 10, Very good, (1,001 reviews)
"Fantastic place to stay! The staff was amazing!"
United States
Catherine
The price is ￥17,350
￥19,941 total
includes taxes & fees
Nov 22 - Nov 23
Hampton Inn St. Charles St. Peters
A Holiday Inn Express & Suites hotel with a covered entrance and a brick facade.

13. Holiday Inn Express Hotel and Suites St. Charles by IHG

Holiday Inn Express Hotel and Suites St. Charles by IHG
3.0 star property
St. Charles
8.2 out of 10, Very good, (772 reviews)
"As always with a Holiday Inn property, our room was clean and very comfortable. The staff was very friendly. Breakfast was good and served hot."
United States
sharon
The price is ￥17,750
￥20,400 total
includes taxes & fees
Nov 27 - Nov 28
Holiday Inn Express Hotel and Suites St. Charles by IHG
A reception desk with a wooden counter, a computer, a telephone, and a small plant. There are three pendant lights above the desk.

14. Country Inn & Suites by Radisson, St. Peters, MO

Country Inn & Suites by Radisson, St. Peters, MO
2.5 star property
St. Charles
8.0 out of 10, Very good, (1,001 reviews)
"Great location. Friendly staff decent breakfast."
United States
Heather
The price is ￥13,807
￥15,871 total
includes taxes & fees
Nov 22 - Nov 23
Country Inn & Suites by Radisson, St. Peters, MO
A hotel room with a bed, a bedside table, and a window with curtains.

15. Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
St. Charles
6.8 out of 10, (1,005 reviews)
"Was an acceptable stay."
United States
Chris
The price is ￥9,984
￥11,474 total
includes taxes & fees
Nov 9 - Nov 10
Relax Inn Saint Charles
A modern living room with a sofa, armchair, and coffee table. A flat-screen TV is mounted on a stand, and a staircase is visible in the background.

16. Sleep Inn Saint Charles North

Sleep Inn Saint Charles North
2.5 star property
St. Charles
5.8 out of 10, (564 reviews)
"Great stay!"
United States
Christine
The price is ￥11,612
￥13,345 total
includes taxes & fees
Nov 28 - Nov 29
Sleep Inn Saint Charles North
A multi-story hotel with a central entrance and a sign reading 'WOODSPRING SUITES'.

17. WoodSpring Suites St Louis St Charles

WoodSpring Suites St Louis St Charles
2.5 star property
St. Charles
5.6 out of 10, (308 reviews)
"Clean and staff was nice."
United States
Erica
The price is ￥13,469
￥15,480 total
includes taxes & fees
Nov 11 - Nov 12
WoodSpring Suites St Louis St Charles
A hotel room with a large bed, a desk, and a television.

18. Home2 Suites by Hilton St. Charles St.Louis

Home2 Suites by Hilton St. Charles St.Louis
3.0 star property
St. Charles
The price is ￥17,414
￥19,321 total
includes taxes & fees
Dec 6 - Dec 7
Home2 Suites by Hilton St. Charles St.Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top St. Charles Hotel Reviews

Moonrise Hotel

Moonrise Hotel

8/10 Good
"This was our 4th stay this year and while we would certainly stay again I was disappointed by the cleanliness of the room. The garbage had not been taken out and a towel from the previous guests was still in the bathroom."
Meaghan 1-night trip
Posted 4 hours ago
Moonrise Hotel

Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Charles?
During your visit, you might want to enjoy the casinos and shopping which St. Charles is known for.
What's the best luxury hotel in St. Charles?
Ameristar Casino Resort and Spa is a luxury hotel with 6 restaurants and 2 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay.
When can I expect good weather in St. Charles?
Planning for the weather is an important factor for making your trip to St. Charles a success, especially when you're splurging. The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for St. Charles is 46 inches.
What's there to see and do in St. Charles?
When you're in St. Charles, enjoy exploring the sights and attractions here including Historic Main Street, Katy Trail, and Lewis & Clark Boathouse and Nature Center. If you have a little extra time during your trip, you might want to make a stop at St Charles Convention Center and Ameristar Casino St. Charles.