Find Luxury Hotels in St. Charles, MO

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Check availability on St. Charles Luxury Hotels

Our top choices for St. Charles luxury hotels

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very Good, (1,003 reviews)
  • cleanliness
    Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
The price is ¥25,356
¥32,276 total
includes taxes & fees
Apr 27 - Apr 28
Ameristar Casino Resort and Spa

The Inn at Elijah McLeans

The Inn at Elijah McLeans
4.0 star property
Washington
9.0 out of 10, Wonderful, (137 reviews)
The price is ¥19,137
¥21,788 total
includes taxes & fees
Apr 15 - Apr 16
The Inn at Elijah McLeans

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1,520 reviews)
The price is ¥15,996
¥20,939 total
includes taxes & fees
Apr 14 - Apr 15
River City Casino & Hotel

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1,922 reviews)
  • cleanliness
    Boutique retreat blends urban charm with luxury, from rooftop views to Egyptian cotton and rainfall showers.
The price is ¥22,201
¥26,403 total
includes taxes & fees
Apr 19 - Apr 20
Moonrise Hotel

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,006 reviews)
The price is ¥20,171
¥23,788 total
includes taxes & fees
May 8 - May 9
Hyatt Regency St. Louis at The Arch

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,277 reviews)
  • cleanliness
    Historic downtown St. Louis hotel offers elegant luxury in a preserved baroque setting.
The price is ¥21,358
¥25,402 total
includes taxes & fees
Apr 19 - Apr 20
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.6 out of 10, Excellent, (1,000 reviews)
The price is ¥25,672
¥30,484 total
includes taxes & fees
Apr 26 - Apr 27
The Cheshire

The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1,009 reviews)
  • cleanliness
    Opulent downtown retreat with pillowtop beds, soaking tubs, and Italian dining moments from Busch Stadium.
The price is ¥24,528
¥28,682 total
includes taxes & fees
Apr 19 - Apr 20
The Westin St. Louis

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,032 reviews)
The price is ¥20,766
¥24,490 total
includes taxes & fees
Apr 19 - Apr 20
Hilton Pennywell St. Louis at the Arch

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,004 reviews)
  • cleanliness
    Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.
The price is ¥74,857
¥87,530 total
includes taxes & fees
Apr 15 - Apr 16
Four Seasons Hotel St Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top St. Charles Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Charles?
During your visit, you might want to enjoy the casinos and shopping which St. Charles is known for.
What's the best luxury hotel in St. Charles?
Ameristar Casino Resort and Spa is a luxury hotel with 6 restaurants and 2 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay.
When can I expect good weather in St. Charles?
Planning for the weather is an important factor for making your trip to St. Charles a success, especially when you're splurging. The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for St. Charles is 46 inches.
What's there to see and do in St. Charles?
When you're in St. Charles, enjoy exploring the sights and attractions here including Historic Main Street, Katy Trail, and Lewis & Clark Boathouse and Nature Center. If you have a little extra time during your trip, you might want to make a stop at St Charles Convention Center and Ameristar Casino St. Charles.