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Dec 13 - Dec 14
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Dec 14 - Dec 15
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Our top choices for Santa Clara hotels

Outdoor pool, open 7:00 AM to 10:30 PM, free cabanas, pool umbrellas
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.6 out of 10, Excellent, (1851)
Escape at this Tocumen resort where lush gardens create a peaceful retreat. Just minutes from PTY airport with free shuttle service, guests enjoy 2 tennis courts, casino, and La Veranda restaurant. The serene pool area offers a calm setting after exploring nearby Metromall.
"Clean room and friendly staff "
United States
Delcides
The price is ￥19,444
￥21,388 total
includes taxes & fees
Dec 15 - Dec 16
Riande Aeropuerto Hotel & Casino
View from property
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (638)
Unwind at this premium Panama City retreat featuring an 18-hole golf course and rejuvenating spa treatments. Just minutes from Multiplaza Pacific Mall, guests enjoy 2 restaurants serving local cuisine, a refreshing outdoor pool, and attentive service.
"As usual the stay was amazing in this hotel"
United States
Jose
The price is ￥36,109
￥39,720 total
includes taxes & fees
Dec 14 - Dec 15
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Food and drink
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
Cerro Viento
8.8 out of 10, Excellent, (1004)
Located in San Miguelito, this hotel offers easy access to Multiplaza Pacific Mall and Metromall Panama. Enjoy international cuisine at Centro restaurant, take a refreshing swim, or work out at the fitness center. Guests praise the exceptional staff.
"The hotel is conveniently close to the airport and shopping centres. "
United States
Samantha
The price is ￥15,760
￥17,336 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Courtyard by Marriott Panama Metromall
Outdoor pool, sun loungers
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (4654)
Immerse yourself in Panama City elegance just minutes from Avenida Balboa and Via Espana. This luxurious hotel offers 3 restaurants serving international cuisine, an inviting outdoor pool, and complimentary breakfast. Iglesia del Carmen Station is only 11 minutes away.
"Awesome great place to stay "
United States
Herbert
The price is ￥19,925
￥21,918 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Hotel Riu Plaza Panama
Lobby
Hyatt Regency Panama City

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Bella Vista
10.0 out of 10, Exceptional, (123)
Relax at this upscale Panama City hotel featuring a spa, restaurant and 2 bars. Just a 15-minute walk to Avenida Balboa and Cinta Costera, with Albrook Shopping Mall only 5 minutes by car. Iglesia del Carmen Station is 6 minutes away on foot.
"Great hotel fair price"
United States
Santiago
The price is ￥21,034
￥23,137 total
includes taxes & fees
Dec 20 - Dec 21
Hyatt Regency Panama City
Terrace/patio
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2128)
Situated near Avenida Balboa and Cinta Costera, this Panama City hotel offers international cuisine at Restaurant del Loft Coral. Guests can enjoy hot stone massages, swim in the outdoor pool, or work out in the fitness center while appreciating the free breakfast.
"Great location, friendly staff, excellent views and the best breakfast around."
Canada
Gregory
The price is ￥16,785
￥18,464 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Plaza Paitilla Inn Hotel
50-inch LED TV with satellite channels
Arcadia Condo Suites

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (160)
"Everything was great, helpful staff, great room , clean, excellent service!"
United States
Gregory Walter
The price is ￥10,283
￥18,509 total
includes taxes & fees
Dec 15 - Dec 16
Arcadia Condo Suites
Daily buffet breakfast (PAB 21 per person)
Sheraton Grand Panama

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (990)
Immersive spa retreat minutes from Multiplaza Pacific Mall. Enjoy 3 diverse restaurants, 2 stylish bars, and a refreshing outdoor pool with poolside service. Guests praise the exceptional staff and convenient access to Albrook Shopping Mall.
"Was amazing food was delicious and stay was great "
United States
Amanda
The price is ￥20,851
￥22,936 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Sheraton Grand Panama
Lobby
The Executive Hotel

The Executive Hotel

The Executive Hotel
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (1002)
Located near Iglesia del Carmen Station, this hotel offers an outdoor pool, steam room, and fitness center. Enjoy meals at Cafe Ejecutivo or unwind at the bar after exploring nearby Albrook Shopping Mall and Avenida Balboa. Free breakfast, WiFi, and parking enhance your stay.
"Clean room, friendly staff, great breakfast daily. I would always recommend this hotel to my friends and family. "
United States
Roxanne Timolyn Thomas
The Executive Hotel
Garden
Radisson Hotel Panama Canal

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador
8.4 out of 10, Very Good, (1001)
"Wonderful staff and easy checkin!"
United States
Kristin
The price is ￥10,860
￥11,946 total
includes taxes & fees
Dec 22 - Dec 23
Radisson Hotel Panama Canal
4 outdoor pools, free cabanas, pool umbrellas
JW Marriott Panama

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1004)
Experience Panama City in style at this luxury hotel with 4 outdoor pools, a poolside bar, and spa services. Just steps from Multiplaza Pacific Mall and Avenida Balboa, enjoy 3 restaurants, including MASI with Latin American cuisine. Free WiFi and a 24-hour fitness center complete your stay.
"Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel."
United States
Sarran
The price is ￥40,355
￥44,390 total
includes taxes & fees
Dec 14 - Dec 15
JW Marriott Panama
Reception
MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
Amador
8.2 out of 10, Very Good, (184)
Surrounded by coastal charm, this hotel offers 6 restaurants and 3 bars for diverse dining experiences. Free breakfast, WiFi, and parking enhance every stay, with Amador Causeway and Albrook Shopping Mall just minutes away.
"Great location "
United States
itzel
The price is ￥10,122
￥11,134 total
includes taxes & fees
Dec 15 - Dec 16
MARINN Tropical Vibes Hotel
Front of property
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very Good, (1267)
Located on Avenida Balboa, this luxury hotel dazzles with a casino and rooftop pool. Travelers can unwind at the spa with deep-tissue massages or savor cuisine at two restaurants. Three bars and complimentary breakfast enhance the stay.
"Clean rooms, staff was amazing!!"
United States
Christopher
The price is ￥19,051
￥20,956 total
includes taxes & fees
Dec 19 - Dec 20
Megapolis Hotel Panamá
View from room
The Beach House

The Beach House

The Beach House
3.0 star property
Amador
8.4 out of 10, Very Good, (407)
Escape to this Panama City hotel with an outdoor pool and refreshing pool bar. Located near Fuerte Amador Resort, this coastal retreat offers free WiFi and parking. Albrook Shopping Mall and Cinta Costera are just a short drive away.
"Fantastic location on Amador Causeway and access to paddleboarding, restaurants, nightlife and family friendly events. One cool sloth in the tree overhanging the walkway at the Culebra nature area right by the prroperty."
United States
Cynthia
The Beach House
Daily buffet breakfast (PAB 10 per person)
Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama
3.5 star property
Bella Vista
7.6 out of 10, Good, (695)
Discover Panama City's vibrant scene from this hotel near Avenida Balboa and Cinta Costera. After sightseeing, unwind in the outdoor pool, sauna, or steam room. Guests praise the helpful staff and overall value at this well-located retreat.
"The breakfast was great, I love the pool."
United States
Estefani
The price is ￥8,021
￥8,823 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hospedium Princess Hotel Panama
Sports facility
Hilton Panama

Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (1000)
"Great place to stay."
United States
Salvador
The price is ￥28,944
￥31,838 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Hilton Panama
Front of property - evening/night
Principe Hotel and Suites

Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1588)
"Room was ok ac good staff was good "
United States
Kerro
The price is ￥7,791
￥8,570 total
includes taxes & fees
Dec 27 - Dec 28
Principe Hotel and Suites
Outdoor pool, sun loungers
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Bella Vista
8.8 out of 10, Excellent, (1002)
Escape to this Panama City sanctuary offering an outdoor pool and poolside bar. Indulge at the spa with massages and facials or enjoy international cuisine at La Brasserie restaurant. Just 5 minutes from Vía Argentina station and minutes from popular malls.
"Amazing amazing service"
United States
KFIR
The price is ￥24,723
￥27,195 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
2 restaurants, local cuisine
W Panama

W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1002)
Savor panoramic views from the rooftop terrace while enjoying 2 restaurants and an outdoor pool. Just a 5-minute walk from Iglesia del Carmen Station, with 3 hot tubs to relax in after exploring nearby Albrook Shopping Mall.
"It is a hotel with very comfortable and nicely designed rooms in the heart of Panama City. The hotel staff is efficient, attentive and friendly."
United States
SVETLANA
The price is ￥33,702
￥37,072 total
includes taxes & fees
Jan 12 - Jan 13, 2026
W Panama
2 bars/lounges, poolside bar
Waldorf Astoria Panama

Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1001)
Escape to this elegant hotel with 2 restaurants serving French cuisine and a full-service spa offering massages. Enjoy the outdoor pool and poolside bar after exploring nearby attractions like Cinta Costera. Just minutes from public transportation for city adventures.
"I loved everything about my stay "
United States
Stephanie
The price is ￥34,298
￥37,728 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Waldorf Astoria Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santa Clara attractions

Culebra Cut

You can find out about the history of Santa Clara with a visit to Culebra Cut. Check out the casinos and top-notch restaurants in this walkable area.
See properties

Learn more about Santa Clara

Santa Clara awaits: its natural setting, monuments, history, and more!

See all hotels in Santa Clara
Adobe

Top Santa Clara Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Everything was amazing"
shalena 7-night trip
Posted 1 day ago
Hotel Riu Plaza Panama

More cheap stays in Santa Clara

Magnolia Inn

Magnolia Inn

8-18 Calle 8 y Calle Boquete Panama City Panama
The price is ￥9,199 per night from Dec 14 to Dec 15
￥9,199
￥10,119 total
Dec 14 - Dec 15
includes taxes & fees
8.8/10 Excellent! (410 reviews)

Frequently asked questions

What's the best place for a stay in Santa Clara?
Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are Las Americas Golden Tower Panama and Megapolis Hotel Panamá. See all available top hotels, or vacation rentals in Santa Clara.
What's the top vacation rental in Santa Clara?
Oasis with pool near panama canal: This vacation home rental outside of Santa Clara offers an outdoor pool, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the garden in this rental home to help you unwind. See all vacation rentals in Santa Clara.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.
Where can I learn more about changing or cancelling my trip to Santa Clara?
To access more information about rescheduling or cancelling your trip to Santa Clara, go to https://www.expedia.com/service/.
What's the best place to stay near Culebra Cut?
Gamboa Rainforest Reserve is one of the top choices for your stay based on our traveler data, and this 3.5-star hotel offers a marina and a full-service spa. It's located 2.9 mi (4.7 km) from Culebra Cut. Other good options within 5 miles include Canopy Bed & Breakfast and Casa en Gamboa al lado Canal de Panama.
What is staying in Santa Clara like?
Visitors can enjoy all that Santa Clara has to offer including its monuments. A top sight in the area is Albrook Shopping Mall. There are 1682 hotels and other accommodations in the surrounding area. Find out more about Santa Clara.
What is there to see in Santa Clara?
A favorite place to visit is Culebra Cut. Additionally, you'll find Albrook Shopping Mall in the area. Check out what more to see and do in Expedia's Santa Clara guide.
What's the seasonal weather like in Santa Clara?
The hottest months are usually April and March with an average temp of 79°F, while the coldest months are January and February with an average of 78°F. The rainiest months in Santa Clara are July, August, November, and October, with each month seeing an average of 11 inches of rainfall.

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