Santa Ana
Panama City
Popular places to visit
Multiplaza Pacific Mall
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Avenida Balboa
You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.
Cinta Costera
Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.
Amador Causeway
You can learn about the history of Ancon with a stop at Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.
Calle 50
You can find out about the history of Panama City with a trip to Calle 50. Discover the area's casinos, or seek out its local tours.
Uruguay Street
During your visit to Panama City, you can do some window-shopping at Uruguay Street. While in this family-friendly area, you can savor the top-notch restaurants.
Things to do
Panama City: Zip Line Experience Over The City
The Panama Barcrawl - The OG Crawl (Panama City, Panama)
Panama City: POIN Swing Experience
From Panama City: Monkey Islands Tour on Gatun Lake
Panama City Visit an Indian town Embera and waterfall with lunch
Santa Ana Hotel Deals
Casco View Apartments
I would definitely stay here again! The immediate surrounding neighborhood is a little run down, but it’s much better only a few blocks over. The property itself is still really nice and its really convenient walk to Casco Viejo.
Reviewed on Mar 19, 2026
Hotel Riu Plaza Panama
Fantastic breakfast and pool in the heart of the city.
Reviewed on Mar 22, 2026
Crowne Plaza Panama Airport by IHG
Amazing
Reviewed on Mar 21, 2026
Sheraton Grand Panama
Breakfast was great , clean room and staff was nice
Reviewed on Mar 20, 2026
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
W Panama
The spa was clean and relaxing
Reviewed on Mar 21, 2026
Other neighborhoods around Santa Ana
Casco Viejo
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
San Felipe
If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.
El Chorrillo
While there might not be top attractions in El Chorrillo, you can explore the larger area and discover places like Albrook Shopping Mall and Maracana Stadium.
Calidonia
You might enjoy the shopping while in Calidonia. Cinta Costera is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.
Balboa
The restaurants and shopping are a few reasons travelers visit Balboa. Though there aren't many top sights in the neighborhood, you can visit Albrook Shopping Mall and Flag of Cerro Ancón, a few notable attractions nearby.
Curundu
While Curundu isn't home to many top sights, Albrook Shopping Mall and Iglesia del Carmen are some notable places to visit nearby.
