A coastal fortification with a lighthouse, rocky hills, and clear blue sea.

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Check prices for these dates

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Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

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Our top choices for Santa Ana hotels

A hotel room with a large bed, a desk with a chair, a window with curtains, and a wall-mounted TV.

1. Posadas de España Cartagena

Posadas de España Cartagena
3.5 star property
Hondón, 7.3 km from Santa Ana
8.8 out of 10, Excellent, (430 reviews)
"Great place to stay!"
United States
Gary
The price is ￥11,145
￥12,260 total
includes taxes & fees
Nov 1 - Nov 2
Posadas de España Cartagena
A grand staircase with a chandelier, a wall with a building mural, and a modern interior design.

2. Hotel Sercotel Alfonso XIII

Hotel Sercotel Alfonso XIII
4.0 star property
Casco Antiguo, 7.3 km from Santa Ana
9.0 out of 10, Wonderful, (361 reviews)
"The location was great for exploring the city"
New Zealand
Craig
The price is ￥13,451
￥14,796 total
includes taxes & fees
Oct 13 - Oct 14
Hotel Sercotel Alfonso XIII
A hotel with a modern facade, a classical building with a dome in the background, and a well-lit entrance.

3. AC Hotel Cartagena

AC Hotel Cartagena
4.0 star property
Casco Antiguo, 8.1 km from Santa Ana
9.6 out of 10, Exceptional, (119 reviews)
"Excellent location in the middle of everything. Breakfast was good but could improve. Parking on property was a plus"
United States
Eduardo
The price is ￥19,631
￥21,594 total
includes taxes & fees
Oct 18 - Oct 19
AC Hotel Cartagena
A modern bar area with a light wood finish, a coffee machine, and three bar stools.

4. NH Campo Cartagena

NH Campo Cartagena
3.0 star property
Cartagena Casco, 6.9 km from Santa Ana
8.8 out of 10, Excellent, (496 reviews)
"very helpful and friendly staff. very clean rooms; great breakfast and very appealing place."
United States
Martha
The price is ￥10,337
￥11,370 total
includes taxes & fees
Nov 1 - Nov 2
NH Campo Cartagena
A hotel lobby with a reception desk, seating area, and a large skylight.

5. Hotel Manolo

Hotel Manolo
3.0 star property
San Antonio Abad, 5.3 km from Santa Ana
7.8 out of 10, Good, (136 reviews)
"Good central location with free parking"
United Kingdom
Alan
The price is ￥10,901
￥11,992 total
includes taxes & fees
Nov 2 - Nov 3
Hotel Manolo
A hotel entrance with a reception desk, seating area, and potted plants.

6. Hotel Sercotel Carlos III

Hotel Sercotel Carlos III
3.0 star property
Casco Antiguo, 7.4 km from Santa Ana
9.0 out of 10, Wonderful, (664 reviews)
"It was a good stay overall"
United Kingdom
Patricia
The price is ￥10,370
￥11,407 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Sercotel Carlos III
A hotel room with a large bed, a desk, a flat-screen TV, a coffee maker, and a window with curtains.

7. B&B Hotel Cartagena Cartagonova

B&B Hotel Cartagena Cartagonova
4.0 star property
Casco Antiguo, 7.4 km from Santa Ana
8.0 out of 10, Very good, (184 reviews)
"Staff super friendly and helpful. Great location and good rooms, especially for the price."
United Kingdom
Linda
The price is ￥9,448
￥10,393 total
includes taxes & fees
Oct 18 - Oct 19
B&B Hotel Cartagena Cartagonova
A poolside view with a large pool, a covered seating area, and a multi-story building with balconies in the background.

8. Ona Mar Menor Golf & Spa

Ona Mar Menor Golf & Spa
5.0 star property
11.3 km from Santa Ana
8.6 out of 10, Excellent, (523 reviews)
"Had an excellent stay at this hotel with family,no complaints."
United Kingdom
Kevin
The price is ￥12,134
￥13,348 total
includes taxes & fees
Oct 12 - Oct 13
Ona Mar Menor Golf & Spa
A swimming pool with a surrounding walkway, palm trees, and a sunset sky.

9. Espacio Finca Alegría

Espacio Finca Alegría
3.0 star property
Perín, 8 km from Santa Ana
8.0 out of 10, Very good, (14 reviews)
"Personnel aimable. Chambre propre avec serviettes de toilette. Le plus : la petite cuisine commune et la piscine. Le moins: avoir un ronfleur dans la chambre en face ! 😁. Mais l'ensemble est très correct. Je recommande."
Spain
BALA
The price is ￥9,401
￥10,341 total
includes taxes & fees
Oct 13 - Oct 14
Espacio Finca Alegría
A modern living room with a grey sofa, a round coffee table, and a dining area with a white table and chairs.

10. Apartamentos Plaza Sevillano

Apartamentos Plaza Sevillano
2.0 star property
Casco Antiguo, 7.6 km from Santa Ana
9.4 out of 10, Exceptional, (12 reviews)
"Excellent location, easy access, spacious, clean, beautiful views and the accommodations were great. "
United States
Betty
The price is ￥11,784
￥11,784 total
includes taxes & fees
Oct 5 - Oct 6
Apartamentos Plaza Sevillano
A bedroom with a bed, curtains, a TV, and a view of the outside.

11. La Casa de las Flores

La Casa de las Flores
3.0 star property
Casco Antiguo, 7.8 km from Santa Ana
9.6 out of 10, Exceptional, (15 reviews)
"Great location and lovely rooms with everything we needed. Would have been good to have somewhere to hang the clothes we washed"
United Kingdom
Emily
The price is ￥23,077
￥25,385 total
includes taxes & fees
Oct 22 - Oct 23
La Casa de las Flores
A room with a laptop on a round table, a TV mounted on the wall, and a potted plant.

12. Apartamentos Turísticos Plaza del Rey

Apartamentos Turísticos Plaza del Rey
4.0 star property
Casco Antiguo, 7.9 km from Santa Ana
9.2 out of 10, Wonderful, (21 reviews)
"Amazing location and apartment. Highly recommend."
Canada
Ivan
The price is ￥10,713
￥11,785 total
includes taxes & fees
Oct 12 - Oct 13
Apartamentos Turísticos Plaza del Rey
A modern building with unique geometric architecture, featuring balconies and patterned facades.

13. Loop INN Hostel Cartagena

Loop INN Hostel Cartagena
2.0 star property
Casco Antiguo, 7.8 km from Santa Ana
9.0 out of 10, Wonderful, (157 reviews)
"It's a nice, clean basic hotel close to the town centre. It's also good value"
United States
STEPHEN
The price is ￥7,662
￥8,429 total
includes taxes & fees
Oct 18 - Oct 19
Loop INN Hostel Cartagena
A bay window with a wooden table and two chairs, a potted plant, and a view of a hillside.

14. Apartamentos Turísticos Gran Vía

Apartamentos Turísticos Gran Vía
3.0 star property
Casco Antiguo, 7.6 km from Santa Ana
8.0 out of 10, Very good, (29 reviews)
"Spacious. Close to everything. "
Sweden
Veronica
The price is ￥10,532
￥11,420 total
includes taxes & fees
Oct 18 - Oct 19
Apartamentos Turísticos Gran Vía
A view from a balcony with a wrought iron railing, overlooking ancient ruins and a grassy area.

15. Apartamentos turísticos Teatro Romano

Apartamentos turísticos Teatro Romano
2.0 star property
Casco Antiguo, 8 km from Santa Ana
7.8 out of 10, Good, (10 reviews)
"A lovely big apartment in a great location. Not suitable for suitcases so we left our big bags in carpark as we were only staying one night. View of Roman theatre great. Room was clean but almost no provisions like water, tea, milk and shampoo. Come prepared! "
United Kingdom
Dani
The price is ￥11,608
￥11,608 total
includes taxes & fees
Oct 5 - Oct 6
Apartamentos turísticos Teatro Romano
A modern living room with a sofa, two armchairs, a wooden coffee table, and a TV on a stand.

16. Puerta Real

Puerta Real
3.0 star property
Casco Antiguo, 7.6 km from Santa Ana
9.6 out of 10, Exceptional, (23 reviews)
"Clean, nice and nice staff "
United States
Mansour
The price is ￥13,543
￥14,431 total
includes taxes & fees
Oct 5 - Oct 6
Puerta Real
A hallway with a stone wall, a wooden door, and a white tiled floor.

17. Apartamentos Turísticos Insulae

Apartamentos Turísticos Insulae
3.0 star property
Casco Antiguo, 7.9 km from Santa Ana
8.8 out of 10, Excellent, (6 reviews)
"Very dark room but only there to sleep so fine. "
United Kingdom
Paula
The price is ￥10,713
￥11,785 total
includes taxes & fees
Oct 6 - Oct 7
Apartamentos Turísticos Insulae
A marina with numerous boats docked, surrounded by palm trees and a clear view of the sea.

18. Hotel Cristina

Hotel Cristina
3.0 star property
15.4 km from Santa Ana
9.4 out of 10, Exceptional, (195 reviews)
"Great hotel in a super location with very pleasant staff and an especially good breakfast. "
United Kingdom
Susan
The price is ￥10,587
￥11,646 total
includes taxes & fees
Oct 18 - Oct 19
Hotel Cristina
A buffet with various food items and beverages.

19. Hotel 525

Hotel 525
4.0 star property
16.9 km from Santa Ana
9.0 out of 10, Wonderful, (859 reviews)
"Excellent hotel in a great location."
United States
Gary S
The price is ￥16,150
￥17,765 total
includes taxes & fees
Oct 28 - Oct 29
Hotel 525
A modern living room with a sofa, a dining table, and a staircase.

20. Apartamentos Centro Histórico

Apartamentos Centro Histórico
3.0 star property
Casco Antiguo, 7.8 km from Santa Ana
7.8 out of 10, Good, (38 reviews)
"very clean, everything you needed in the kitchen,"
United Kingdom
Linda
The price is ￥10,202
￥10,202 total
includes taxes & fees
Oct 6 - Oct 7
Apartamentos Centro Histórico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.
A coastal town with a lighthouse, rocky cliffs, and the ocean.
Photo by INDALOMANIA
Open Photo by INDALOMANIA

Diputación de Rincón de San Ginés

Unique features of Diputación de Rincón de San Ginés include the golf courses and spas. Make a stop by Calblanque, Monte de las Cenizas y Peña del Águila Regional Park or Islas Menores while you're exploring the area.

A coastal lighthouse on a rocky outcrop with a paved walkway nearby.
Photo by Валерий Дед
Open Photo by Валерий Дед

Cabo de Palos

Travelers like the historic sites in Cabo de Palos, and Lighthouse of Cabo de Palos is a top attraction you might want to visit.

An ancient amphitheater with a circular stage and tiered seating, surrounded by historic buildings and mountains in the background.

El Beal

El Beal is noteworthy for its restaurants, and you can make a stop at top attractions like Los Nietos Beach and El Vivero.

An ancient amphitheater surrounded by modern buildings and a port.
Photo by V & A
Open Photo by V & A

Cartagena Casco

Historic sites, museums, and waterfront views are some highlights of Cartagena Casco. Make a stop by Punic wall of Cartagena or Gran Hotel while you're exploring.

A sunset over a calm body of water with a silhouette of distant mountains.

La Azohia

You'll enjoy the monuments and historic sites in La Azohia. You might want to make time for a stop at Playa de San Ginés or Playa de La Chapineta.

Top Santa Ana Hotel Reviews

Hotel Lodomar Spa & Talasoterapia

Hotel Lodomar Spa & Talasoterapia

10/10 Excellent
"Perfect"
PEDRO FERNANDEZ 9-night trip
Posted 19 hours ago
Hotel Lodomar Spa & Talasoterapia

Frequently asked questions

What is Santa Ana like?
Travelers to Cartagena's Santa Ana neighborhood will be sure to enjoy a stay in this neighborhood.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, it may still be possible to cancel it and receive a refund within 24 hours of your booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to get the best deals in Santa Ana.
Where can I learn more about changing or cancelling my trip to Santa Ana?
To find more details about changing or cancelling your trip to Santa Ana, head over to our customer service page.
What is there to do in this Cartagena neighborhood?
Cartagena Karting Club is one place you might want to visit in the area around Santa Ana. When you're sightseeing around the area, Estadio Municipal de Cartagena and Punic wall of Cartagena are a couple of other sights to visit.

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