Find hotels in Sant'Isidoro from ¥8,827

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Sant'Isidoro hotels

B&B Ghalà

B&B Ghalà
Gallipoli
9.2 out of 10, Wonderful, (46)
Unwind at this B&B with nearby snorkeling adventures and easy access to Baia Verde Beach. Just 2 minutes from Gallipoli Station, guests love the free local cuisine breakfast served daily and convenient location to the Greek Fountain.

"Nice stay and shopping, old town wonderful."
Sweden
Helen Kristin
The price is ¥3,627
¥3,990 total
includes taxes & fees
Jan 18 - Jan 19, 2026
B&B Ghalà

Masseria Stali, The Originals Relais

Masseria Stali, The Originals Relais
Caprarica di Lecce
9.6 out of 10, Exceptional, (102)
This golf country house offers an outdoor pool, 2 bars, a hot tub, and massages. Enjoy local flavors at the on-site restaurant, with easy access to cultural attractions. Near Kalos Archeodromo del Salento and free WiFi and parking enhance your stay.

"Great pool and spacious rooms. "
United Kingdom
Richard
The price is ¥9,489
¥10,438 total
includes taxes & fees
Dec 29 - Dec 30
Masseria Stali, The Originals Relais

Grand Hotel di Lecce

Grand Hotel di Lecce
4.0 star property
Lecce
8.4 out of 10, Very Good, (308)
Immerse yourself in Italian charm at this Lecce hotel, just 1 minute from the rail station. Cool off in the seasonal outdoor pool before enjoying complimentary breakfast and drinks at the stylish bar lounge.

"Beautyful hotel, nice pool, good location."
Norway
Vigdis
The price is ¥14,634
¥16,837 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Grand Hotel di Lecce

Masseria Zanzara

Masseria Zanzara
Leverano
9.2 out of 10, Wonderful, (55)
Immersed in Leverano's countryside, this charming B&B offers a seasonal outdoor pool and restaurant. Enjoy free breakfast, WiFi, and parking while being close to Vincent Brunetti and Scala di Furno Beach attractions.

"Lovely hotel. A tranquil haven with beautiful grounds."
United Kingdom
JoAnne
The price is ¥8,025
¥8,827 total
includes taxes & fees
Dec 22 - Dec 23
Masseria Zanzara

I Bastioni San Domenico - Boutique Hotel

I Bastioni San Domenico - Boutique Hotel
4.0 star property
Gallipoli Historic Center
9.4 out of 10, Exceptional, (143)
Perched in historic Gallipoli, this charming boutique hotel features a scenic rooftop terrace and wine bar. Enjoy local cuisine at Il Bastione restaurant, free breakfast, and WiFi. Located near Frantoio Ipogeo and E. Barba Civic Museum, with the train station just a short walk away.

"enjoyed our stay"
Canada
Laura
I Bastioni San Domenico - Boutique Hotel

Nohasi Palace

Nohasi Palace
5.0 star property
Galatina
9.8 out of 10, Exceptional, (6)
Luxurious Galatina retreat near Basilica of Saint Catherine of Alexandria features an outdoor pool with poolside bar and hot tub. The on-site spa offers deep-tissue massages and facials, while free breakfast, WiFi, and parking enhance your Italian getaway.

"A fantastic building, beautifully restored, really a small palazzo. Very ambitious owners, fine restaurant and the suite was splendid. Perfect for exploring Puglia, but feels like it’s really a place to get married at. We’d love to come back! "
Sweden
Jacob
Nohasi Palace

Sangiorgio Resort & Spa

Sangiorgio Resort & Spa
5.0 star property
Cutrofiano
9.6 out of 10, Exceptional, (51)
Immerse yourself in Italian charm at this Cutrofiano retreat. Swim in 2 outdoor pools or relax at the indoor pool and poolside bar. Visit the spa for rejuvenating massages, facials, or body treatments after exploring nearby museums.

"This is a lovely hotel for relaxing & enjoying peace & tranquility of Salento The rooms are spacious lovely & super comfy beds & well cleaned every day The restaurant has a daily menu & food is great quality, my wife is Vegan and the staff & Chef made dinners for her every night!! The staff are absolutely awesome! Nothing is too much trouble for them they really are fantastic & worked hard to make our stay perfect for us Valentina Daisy Maria Marianna & Ricardo Thank you all so much!! "
United Kingdom
wayne
The price is ¥26,333
¥28,966 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Sangiorgio Resort & Spa

Arthotel & Park Lecce

Arthotel & Park Lecce
4.0 star property
Lecce
8.4 out of 10, Very Good, (167)
Unwind in this Lecce retreat with a rejuvenating spa offering deep-tissue massages and facials. Enjoy Italian cuisine at ArteCrazia restaurant, refresh in the indoor pool, or relax at the poolside bar after exploring nearby attractions.

"The room was spacious and very nice and clean, the breakfast very nice and the people very welcoming. Overall a great experience and an extremely beautiful hotel "
Greece
Anastasia
The price is ¥10,398
¥12,176 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Arthotel & Park Lecce

Le Scuderie - Castello Monaci

Le Scuderie - Castello Monaci
Salice Salentino
10.0 out of 10, Exceptional, (16)
In Salice Salentino, this charming B&B offers free breakfast, WiFi, and parking within a restored castle setting. Relax with massages, dine at the restaurant, or explore the seasonal outdoor pool and garden near local attractions.

"Beautiful place! And the staff amazing"
United States
Erika
Le Scuderie - Castello Monaci

Dimora San Giuseppe

Dimora San Giuseppe
Lecce Historic Center
9.6 out of 10, Exceptional, (29)
"Fabulous place to stay, gorgeous rooms, lovely breakfast and great location"
Australia
Francesca
Dimora San Giuseppe

Alvino Suite & Breakfast

Alvino Suite & Breakfast
Lecce Historic Center
8.2 out of 10, Very Good, (40)
"Alvino is a wonderful bakery. The room I had that was billed as being part of Alvino was in another building. Entry was through a trash strewn alley. I had a second floor room with no windows, no sprinklers, no smoke detector and only one exit. The water in the shower consistently cycled comfortable, too hot, too cold, comfortable, too hot, too cold. I highly recommend the bakery, which sadly was closed one of the two days I was there, but do yourself a favor and stay elsewhere, "
United States
Frank
Alvino Suite & Breakfast

Palazzo Marini B&B di Charme

Palazzo Marini B&B di Charme
Lecce Historic Center
9.6 out of 10, Exceptional, (71)
Experience Italian elegance at this intimate B&B near Lecce Rail Station. The rooftop terrace offers a perfect spot to unwind after exploring nearby Convitto Palmieri and Sant'Anna Church. Complimentary WiFi and daily breakfast enhance your stay.

"Great location! Easy walk to sights, many restaurants, and the train station."
United States
Josephine
Palazzo Marini B&B di Charme

Le Dune Suite Hotel

Le Dune Suite Hotel
4.0 star property
Porto Cesareo
8.6 out of 10, Excellent, (57)
This beach hotel near Torre Lapillo Beach offers 2 restaurants, a spa with massages and body wraps, and a rooftop terrace. Enjoy the sauna, steam room, and beach bar after exploring nearby Scala di Furno Beach or returning from a day trip to Carmiano-Magliano Station.

"Perfect location for an excellent beach - with great amenities. Excellent half board package delivered a great dining experience. Within a reasonable walking distance to the town centre and the restaurants/bars/shopping/sights there. The whole hotel team went to great lengths to look after us and no ask was too much. Highly recommended."
United Kingdom
James
The price is ¥18,770
¥20,648 total
includes taxes & fees
Dec 22 - Dec 23
Le Dune Suite Hotel

Tenuta Masseria & Spa Chicco Rizzo

Tenuta Masseria & Spa Chicco Rizzo
Sternatia
10.0 out of 10, Exceptional, (20)
Immersed in the countryside of Sternatia, this elegant masseria offers rejuvenating hot stone massages and regional flavors at Ristorante Masseria. Swim in the outdoor pool before enjoying drinks at the poolside bar, just minutes from cultural attractions.

"We enjoyed our evening here — especially the delicious dinner! The dishes prepared at their restaurant were a highlight of our trip"
United States
Cara
Tenuta Masseria & Spa Chicco Rizzo

Casa Mamma Elvira

Casa Mamma Elvira
Lecce Historic Center
9.8 out of 10, Exceptional, (118)
Experience Casa Mamma Elvira's charm with Italian cuisine at 3 restaurants and a stylish wine bar. Located near Church of Santa Maria della Grazia and Castle of Charles V, this B&B offers free breakfast and is just a 13-minute walk from Lecce Rail Station.

"Excellent stay at Casa Mamma Elvira. Conveniently located in Lecce's "old town" and a short walk to all the sites, restaurants, and shops. "
Canada
Marc
The price is ¥19,950
¥22,499 total
includes taxes & fees
Dec 22 - Dec 23
Casa Mamma Elvira

Arryvo

Arryvo
Lecce Historic Center
9.6 out of 10, Exceptional, (201)
Just steps from Lecce Rail Station, this charming hotel offers free breakfast and WiFi near Old Town. Unwind at the bar or grab a bite at the café. Guests love the helpful staff and easy access to Paisiello Theatre and Porta Napoli.

"Very nice modern hotel, close to the old town, great staff and excellent breakfast!"
United States
marina
Arryvo

PlazaCarrisi Hotel & Spa

PlazaCarrisi Hotel & Spa
4.0 star property
Cellino San Marco
9.6 out of 10, Exceptional, (38)
Wake up to a complimentary buffet breakfast at this tranquil hotel featuring daily housekeeping and free WiFi. Perfectly positioned near Cantine Due Palme and Masseria Li Veli Winery for local wine exploration.

"Top hotel in a delightful Puglia village."
United Kingdom
Stuart
The price is ¥15,112
¥16,992 total
includes taxes & fees
Jan 4 - Jan 5, 2026
PlazaCarrisi Hotel & Spa

Pollicastro Boutique Hotel

Pollicastro Boutique Hotel
4.0 star property
Lecce Historic Center
9.8 out of 10, Exceptional, (130)
Stunning boutique accommodation in Lecce offers a rooftop terrace where guests can take in panoramic sights. Enjoy free cooked-to-order morning meals, relax at the bar, or walk to Lecce Rail Station. The Faggiano Museum and Gate of Saint Blaise await nearby.

"Hotel was very clean, staff were helpful and location was great. "
United Kingdom
Amanda
The price is ¥23,178
¥26,235 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Pollicastro Boutique Hotel

Barone Liberty & Luxury SPA-Boutique Hotel

Barone Liberty & Luxury SPA-Boutique Hotel
Gallipoli
9.6 out of 10, Exceptional, (17)
Immerse in Italian coastal charm at this beachside B&B near Gallipoli Greek Fountain and Castle. The full-service spa offers massages and aromatherapy, while a hot tub awaits after sightseeing. Just an 8-minute walk from the train station with complimentary breakfast and WiFi.

"Beautiful accommodation, lovely room. Just a short walk from Corso Roma - the main road through Gallipoli, with many restaurants bars, and leads up to the old town."
United Kingdom
Mark
The price is ¥12,686
¥13,954 total
includes taxes & fees
Dec 29 - Dec 30
Barone Liberty & Luxury SPA-Boutique Hotel

Masseria Mazzetta Salento

Masseria Mazzetta Salento
Salice Salentino
9.6 out of 10, Exceptional, (18)
Wake to local cuisine breakfast at this tranquil Salice Salentino retreat. Enjoy garden strolls and terrace relaxation between visits to Forum Eventi. Free WiFi and parking enhance your stay at this welcoming Puglian hideaway.

"Fantastic place for distinguished travellers, a piece of genuine Italy, as imagined in books and movies, perfect!"
United States
Alexey
The price is ¥21,326
¥23,460 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Masseria Mazzetta Salento
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Sant'Isidoro attractions

Learn more about Sant'Isidoro

Turquoise waters lap against the golden sands of Spiaggia di Sant'Isidoro, where locals and visitors alike spread colorful towels under rental umbrellas. Venture into Porto Selvaggio and Palude del Capitano Regional Nature Park, where hiking trails wind through Mediterranean scrub to hidden rocky coves perfect for afternoon snorkeling.

One of the most beautiful day moment..
Photo by Cesare Zuccaro
Open Photo by Cesare Zuccaro

Top Sant'Isidoro Hotel Reviews

More cheap stays in Sant'Isidoro

Hotel Sara

Hotel Sara

Via dei trulli 15 Nardò LE

Frequently asked questions

Where is the best place to stay in Sant'Isidoro?
Grand Hotel di Lecce, located 15.4 mi (24.8 km) from the heart of Sant'Isidoro, is a top choice for your stay based on our traveler data. Two other options for your trip to the area are Palazzo Sant'Anna Lecce and Sangiorgio Resort & Spa. See all available top hotels, or vacation rentals in Sant'Isidoro.
What are some of the best vacation home rentals that Sant'Isidoro has to offer?
Kalinifta Rooms Apartment: This vacation home rental outside of Sant'Isidoro is located on the waterfront and has a private balcony, a rooftop terrace, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities like a fridge and kitchenware can make your vacation run smoothly. You and your friends and family can relax into your vacation with amenities like a garden. See all vacation rentals in Sant'Isidoro.
If I need to cancel my hotel reservation in Sant'Isidoro, will I receive a refund?
Yes! The majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Sant'Isidoro.
Where can I learn more about changing or cancelling my trip to Sant'Isidoro?
For more details about picking new dates or cancelling your trip to Sant'Isidoro, go to https://www.expedia.com/service/.
What's the best place to stay for families in Sant'Isidoro?
Blu Salento Village is a resort with a private beach and a children's pool, and it's a top choice on Expedia for families. Attractions in the area like Museum of the Sea and Parco Acquatico Splash are also fun for kids of all ages. Find more child-friendly accommodations in Sant'Isidoro.
What's the best pet-friendly hotel in Sant'Isidoro?
Agriturismo La Lucia is a top country house for people traveling with their pets, and offers a restaurant and free WiFi for its human guests. Villa Itaca is another option for a stay with your pet. See more pet-friendly hotel accommodations in Sant'Isidoro.
What's the best place for a beach vacation in Sant'Isidoro?
Blu Salento Village is a top beachfront resort offering free buffet breakfast and free parking, located within a short 6-minute walk of Spiaggia di Sant'Isidoro. Casa Vacanza Marijò is another good choice for your beach trip. See more stays near the beach in Sant'Isidoro.
What are some hotels with pools in Sant'Isidoro?
Grand Hotel di Lecce: Features daily, a seasonal outdoor pool, and complimentary wireless internet access. Sangiorgio Resort & Spa and Masseria & Spa Luciagiovanni are two additional hotels that feature an onsite pool. View all hotels with pools in Sant'Isidoro.
What's the best hotel for staying near Papola Casale Airport (BDS)?
Grande Albergo Internazionale is a popular 4-star hotel featuring free breakfast and a restaurant. It's located a short 1.2 mi (1.9 km) from Papola Casale Airport. Other places to stay within close proximity to the airport include Hotel Executive Inn and Hotel Orientale.
What's it like to stay in Sant'Isidoro?
Visitors to Sant'Isidoro are sure to find plenty to explore and enjoy. In Sant'Isidoro, there are 111 hotels and other accommodations to choose from. Find out more about Sant'Isidoro.
What is there to see in Sant'Isidoro?
The picturesque setting of Spiaggia di Sant'Isidoro and Ionian Sea exemplify the area's natural beauty. A couple of additional sights to add to your agenda are Porto Selvaggio and Palude del Capitano Regional Nature Park and Lido dell' Ancora. Check out what more to see and do in Expedia's Sant'Isidoro guide.
What's the weather like in Sant'Isidoro?
The hottest months are usually August and July with an average temp of 78°F, while the coldest months are January and February with an average of 54°F. Average annual precipitation for Sant'Isidoro is 31 inches.