Find hotels in San Antonio, San Miguelito

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Our top choices for San Antonio hotels

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
12.5 km from San Antonio
8.4 out of 10, Very Good, (1291)
"Clean rooms, staff was amazing!!"
United States
Christopher
The price is ¥23,496
¥25,846 total
includes taxes & fees
Dec 22 - Dec 23
Megapolis Hotel Panamá

ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport
2.5 star property
5.7 km from San Antonio
9.0 out of 10, Wonderful, (37)
"It was a cool unique antique place that had modern touches. The staff was very friendly and helpful. Will definitely stay again. "
United States
Clarissa
The price is ¥18,930
¥20,823 total
includes taxes & fees
Dec 22 - Dec 23
ORHO HOTEL BOUTIQUE PANAMA Airport

Gran Evenia Panama

Gran Evenia Panama
4.5 star property
12.4 km from San Antonio
9.2 out of 10, Wonderful, (195)
"The property was conveniently located near shops, restaurants and casinos. The food at breakfast was good. Although the pancakes could be better. "
United States
Nicole
Gran Evenia Panama

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
15.8 km from San Antonio
9.0 out of 10, Wonderful, (1009)
"Excellent hotel , good breakfast, great location, would highly recommend "
United States
Glen
The price is ¥32,647
¥35,912 total
includes taxes & fees
Dec 23 - Dec 24
Central Hotel Panama Casco Viejo

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
11.9 km from San Antonio
8.8 out of 10, Excellent, (1001)
"Everything was clean and the staff was very cooperative."
United States
Deangelo
The price is ¥25,082
¥27,590 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
23.4 km from San Antonio
8.0 out of 10, Very Good, (1002)
"Great place and location, excellent food choices! "
United States
Francisco
The price is ¥35,954
¥39,549 total
includes taxes & fees
Jan 8 - Jan 9, 2026
The Westin Playa Bonita Panama

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
15.8 km from San Antonio
9.8 out of 10, Exceptional, (258)
"Great location!"
United States
Erik
The price is ¥50,819
¥55,901 total
includes taxes & fees
Dec 23 - Dec 24
Hotel La Compañía Casco Antiguo

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
4.0 star property
12.8 km from San Antonio
7.8 out of 10, Good, (1006)
"Great service and staff. "
United States
Roberto
The price is ¥16,327
¥17,960 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
4 km from San Antonio
9.6 out of 10, Exceptional, (641)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is ¥35,375
¥38,913 total
includes taxes & fees
Jan 17 - Jan 18, 2026
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Hilton Panama

Hilton Panama
5.0 star property
13 km from San Antonio
8.8 out of 10, Excellent, (1001)
"Nice room! Clean. Nice balcony, "
United States
Cassandra
The price is ¥33,165
¥36,481 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Hilton Panama

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
Cerro Viento, 1.4 km from San Antonio
8.8 out of 10, Excellent, (1002)
"The hotel is conveniently close to the airport and shopping centres. "
United States
Samantha
The price is ¥15,956
¥17,552 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Courtyard by Marriott Panama Metromall

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
15.7 km from San Antonio
9.8 out of 10, Exceptional, (560)
"Great hotel and location "
United Kingdom
Russell
The price is ¥58,920
¥64,812 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Sofitel Legend Casco Viejo, Panama City

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
12.4 km from San Antonio
9.0 out of 10, Wonderful, (4696)
"Awesome great place to stay "
United States
Herbert
The price is ¥17,251
¥18,976 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Hotel Riu Plaza Panama

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
6.1 km from San Antonio
8.4 out of 10, Very Good, (2321)
"Spacious room, clean, good breakfast "
United States
Juan
The price is ¥17,353
¥19,088 total
includes taxes & fees
Dec 23 - Dec 24
Crowne Plaza Panama Airport by IHG

Amarla Boutique Hotel Casco Viejo

Amarla Boutique Hotel Casco Viejo
3.0 star property
15.8 km from San Antonio
9.6 out of 10, Exceptional, (106)
"Great little hotel in Casco Viejo. Rooms are small, but comfortable. Reception is a bit odd, but service was nice. "
United States
Frederick
Amarla Boutique Hotel Casco Viejo

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
12.5 km from San Antonio
8.6 out of 10, Excellent, (1456)
"Excellent stay. Wonderful staff, good location and excellent breakfast"
United States
Michael
The price is ¥21,684
¥23,852 total
includes taxes & fees
Dec 22 - Dec 23
Decapolis Hotel Panama City

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
12.8 km from San Antonio
10.0 out of 10, Exceptional, (126)
"Great hotel fair price"
United States
Santiago
The price is ¥24,727
¥27,201 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Hyatt Regency Panama City

MARINN PLACE Financial District

MARINN PLACE Financial District
3.5 star property
12.8 km from San Antonio
9.2 out of 10, Wonderful, (299)
"Second stay, very nice"
Canada
Xiaozhi
The price is ¥17,668
¥19,435 total
includes taxes & fees
Dec 22 - Dec 23
MARINN PLACE Financial District

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
6.2 km from San Antonio
9.4 out of 10, Exceptional, (162)
"Everything was great, helpful staff, great room , clean, excellent service!"
United States
Gregory Walter
The price is ¥11,358
¥19,783 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Arcadia Condo Suites

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
12.8 km from San Antonio
9.4 out of 10, Exceptional, (1000)
"Great staff, super accommodating. Best place to stay in Panama!"
United States
Sebastian
The price is ¥31,645
¥34,809 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Bristol Panama, a Registry Collection Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most.

Cerro Viento

Shopping and restaurants are notable features of Cerro Viento. You might consider a stop by Metromall Panama while you're exploring the neighborhood.

José Domingo Espinar

When in José Domingo Espinar, you can plan a visit to Estadio Rommel Fernandez and Metromall Panama, some noteworthy sights in the nearby area.

Rufina Alfaro

If you're looking for some top things to see and do in Rufina Alfaro and surrounding area, you can visit Metromall Panama and Los Pueblos Commercial Center.

Victoriano Lorenzo

Though Victoriano Lorenzo might not have many top sights, you can venture to the surrounding area to see attractions like Panama Viejo and Estadio Rommel Fernandez.

Amelia Denis de Icaza

Amelia Denis de Icaza might not have many top sights, but El Dorado Mall and Panama Viejo are two attractions nearby that you can check out.

Top San Antonio Hotel Reviews

Frequently asked questions

What's it like in San Antonio?
San Antonio is a neighborhood that travelers like for its shopping and gardens.
If I need to cancel my hotel reservation in San Antonio, will I receive a refund?
Yes, most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to get the best deals in San Antonio.
Where can I learn more about changing or cancelling my trip to San Antonio?
To find more details about rescheduling or cancelling your trip to San Antonio, click here.
What is there to do in this San Miguelito neighborhood?
Metromall Panama, Los Pueblos Commercial Center, and Estadio Rommel Fernandez are just a few of the places to visit in and around San Antonio. While you're out sightseeing, Plaza de Francia and Atrio Mall are a couple of additional sights to visit in San Miguelito.