The Best Hotels Closest to Santo Domingo Square in Cartagena for 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Santo Domingo Square hotels

1. Casa Belle Cartagena Hotel Boutique

San Diego, 0.5 km from Santo Domingo Square

Federico

￥31,852

￥31,852 total

Oct 15 - Oct 16

An indoor corridor with arches, a central column, and a dining area with tables and chairs.

A courtyard with a wooden pergola, palm trees, and potted plants.

A spacious hallway with a wooden staircase, a ceiling fan, and a potted plant with red flowers.

A building with a balcony, arched windows, and a door with a wreath.

2. Hotel Quadrifolio

Cartagena Centro, 0.2 km from Santo Domingo Square

ELIZER

￥47,458

￥47,458 total

Nov 9 - Nov 10

A modern outdoor pool area with a lounge chair and a small table, surrounded by a geometric patterned fence.

A modern hotel room with a large bed, a wooden headboard, a wall-mounted air conditioner, a small desk with a chair, and a decorative plant.

A multi-level atrium with wooden railings, stone columns, and lush greenery.

A lobby with a reception desk, a red sofa, and a staircase leading to an outdoor area with plants.

3. Hotel Boutique Casona del Porvenir

Cartagena Centro, 0.3 km from Santo Domingo Square

Jacqueline

￥31,415

￥31,415 total

Nov 10 - Nov 11

A pool area with stone columns, water features, and outdoor seating.

A breakfast buffet with various food items and condiments.

A corridor with wooden doors, a herringbone floor, a staircase, and a stone wall.

A courtyard with a pool, wooden furniture, and a dining area.

4. Palacio del Agua by Faranda Boutique

Cartagena Centro, 0.3 km from Santo Domingo Square

Marycela

￥37,128

￥37,128 total

Oct 26 - Oct 27

A hotel entrance with a wooden door, a sign reading "Casa la Cartuja," and a white column with a grid-like pattern.

A modern living room with a wooden bench, a small table with books, a white sofa, and decorative wall art.

A hotel room with a large bed, two bedside tables with lamps, a wall-mounted fan, and a window with curtains.

A hallway with a staircase, a wall-mounted planter with various plants, and a tiled wall with a blue mosaic pattern.

5. Casa La Cartujita

San Diego, 0.5 km from Santo Domingo Square

Ruben

￥32,258

￥32,258 total

Oct 17 - Oct 18

A pool area with lounge chairs and a stone wall.

A bar area with wooden chairs, a counter with bottles, and hanging crystal chandeliers.

A dining area with a chandelier, wooden ceiling, and tables set for dining.

A room with wicker furniture, a chandelier, and a view of palm trees through large windows.

6. Hotel Casa San Agustin

Cartagena Centro, 0.3 km from Santo Domingo Square

David

￥91,429

￥91,429 total

Nov 10 - Nov 11

A hallway with a stone floor, wooden beams, and a large potted plant.

A hallway with a stone floor, a large potted plant, wall-mounted light fixtures, and a decorative wall piece.

A table set with various dishes, drinks, and a checkered floor.

A balcony with a railing, a potted plant, and a building with a tiled roof in the background.

7. Privado Designer Boutique Hotel

San Diego, 0.5 km from Santo Domingo Square

Katherine

￥19,886

￥19,886 total

Oct 11 - Oct 12

A swimming pool with a tiled deck, surrounded by lush greenery and a building with a balcony.

A spacious indoor courtyard with a central palm tree, surrounded by various plants and a stone staircase leading to an upper level.

A historic building with multiple stories, large windows, and a balcony.

A multi-story building with a classic architectural style, featuring a central entrance with a dark door, multiple windows on each floor, and decorative ironwork.

8. Cinco Quintas Hotel Boutique

Cartagena Centro, 0.3 km from Santo Domingo Square

Fernando

￥39,737

￥39,737 total

Oct 23 - Oct 24

A grand lobby with a central seating area, a staircase, and a large plant.

A man and a woman relaxing on a striped floating platform in a clear pool.

A grand hallway with high ceilings, ornate columns, and a large chandelier.

9. Four Seasons Hotel & Residences Cartagena

Getsemani, 0.6 km from Santo Domingo Square

john

￥82,321

￥82,321 total

Oct 18 - Oct 19

A hotel room with a large bed, a seating area with cushions, a view of a tower, and a balcony with a railing.

A hotel room with two beds, a small table, a nightstand, a lamp, and a view of greenery through a window.

A spacious room with a ceiling fan, a large flat-screen TV, a wooden cabinet, a sofa, and a view through large glass doors.

A modern living room with a flat-screen TV, sofas, a coffee table, and a large window offering a city view.

10. Hotel Casa Bianca By Faranda Boutique

Cartagena Walled City, 0.4 km from Santo Domingo Square

"We had an amazing stay! The hotel was clean, comfortable, and had everything we needed. Santiago was absolutely wonderful and made us feel very welcome. The young lady assisting with the breakfast service was also amazing and provided such friendly, helpful service. We took full advantage of the breakfast and pool, and both were great. Overall, we really enjoyed our stay and honestly wish we could pick this hotel up and move it around with us whenever we travel so it would always be available!...

Gesemia

￥28,853

￥28,853 total

Nov 10 - Nov 11

A swimming pool with a view of historic buildings, including a church with a dome and bell tower.

A modern bedroom with a large bed, a sofa, and a balcony with plants.

A modern living room with a white coffee table, two sofas, a dining area with a table and chairs, and a large window with blinds.

A balcony with pink flowers, a person holding a drink, and buildings in the background.

11. Casa Claver Loft Boutique Hotel

Cartagena Centro, 0.2 km from Santo Domingo Square

Kevin

￥34,442

￥34,442 total

Nov 10 - Nov 11

A cozy living room with a white sofa, a wicker bench, a coffee table with a bowl of nuts, and a large mirror reflecting the room.

A restaurant with a long wooden table, wicker chairs, hanging lights, and a stone wall.

A restaurant with a checkered floor, wooden tables, and hanging plants.

A rustic indoor garden with a water feature, brick pathway, and lush greenery.

12. Amarla Boutique Hotel Cartagena

Cartagena Centro, 0.1 km from Santo Domingo Square

Matt

￥46,972

￥46,972 total

Nov 2 - Nov 3

A rooftop pool area with lounge seating, a pool, and a view of a historic building.

A hotel room with a bed, a television, a wooden wardrobe, and a wicker chair.

An outdoor seating area with a sofa, chairs, and a large umbrella.

A restaurant with checkered flooring, tables set with wine glasses, and a wall-mounted menu board.

13. Sophia Hotel By OxoHotel

Cartagena Centro, 0.3 km from Santo Domingo Square

Anthony

￥49,355

￥49,355 total

Nov 10 - Nov 11

A courtyard with two lounge chairs, a brick wall, and a tiled roof.

A building with a balcony, arched doorways, and flags.

A spacious living area with a dining table, chairs, a sofa, and a patterned rug.

An outdoor swimming pool with lounge chairs and umbrellas, surrounded by a patio area with tables and chairs.

14. Hotel Casa del Gobernador

Cartagena Centro, 0.2 km from Santo Domingo Square

Peyton

￥54,213

￥54,213 total

Nov 10 - Nov 11

A swimming pool with clear water, surrounded by lush greenery and flowering plants.

A spacious indoor area with a dining table and chairs, a sofa, and a lamp.

A spacious atrium with a central seating area, large windows, and a reflective floor.

A building with a white facade, wooden window bars, and a sign that reads "Bastion."

15. Bastión Luxury Hotel

San Diego, 0.4 km from Santo Domingo Square

Santiago

￥54,388

￥54,388 total

Nov 10 - Nov 11

A pool area with a spiral staircase, lounge chairs, and potted plants.

A restaurant with high arched windows, a chandelier, and neatly set dining tables.

An outdoor patio area with wooden furniture, umbrellas, and a pool.

A spacious living room with two sofas, a wooden coffee table, and a ceiling fan.

16. Casa Pestagua Relais Châteaux

Cartagena Centro, < 0.1 km from Santo Domingo Square

Emil

￥62,691

￥62,691 total

Nov 1 - Nov 2

A dining area with a glass table set for four, surrounded by wicker chairs, with a pool and a building in the background.

A bedroom with a large bed, a stone wall, and a wooden ceiling.

A spiral staircase with a stone finish, surrounded by white walls and potted plants.

17. Upper House

Cartagena Walled City, 0.5 km from Santo Domingo Square

Dallas

￥18,671

￥18,858 total

Oct 20 - Oct 21

A hotel room with a large bed, a desk, a chair, and a balcony with a view of buildings.

A modern hotel room with a large bed, a wooden wardrobe, a desk with a lamp, and a chair.

A two-story building with a white facade, large windows with blue shutters, and a wooden entrance door.

A large, historic building with a central courtyard, surrounded by water and boats.

18. GHL Arsenal Hotel

Getsemani, 0.6 km from Santo Domingo Square

Shayna

￥18,985

￥18,985 total

Nov 10 - Nov 11

A pool area with a clear view of the water, surrounded by lush greenery and a building with arches and a tiled roof.

A spacious living area with a high ceiling, exposed wooden beams, and a fireplace. There are several seating areas with upholstered chairs and a sofa.

A narrow alleyway with wooden doors and balconies, surrounded by lush greenery.

A bathroom with a stone wall, a bathtub, a vanity with a mirror, and a ceiling fan.

19. Casa del Arzobispado Hotel

Cartagena Centro, 0.2 km from Santo Domingo Square

JOHN

￥38,599

￥38,599 total

Oct 14 - Oct 15

A high-ceilinged wooden room with a large bathtub, two small tables, and a bench.

A spacious lobby with a central seating area, a large hanging light fixture, and a polished floor.

A spacious indoor courtyard with a wooden floor, a central seating area with tables and chairs, and a large potted plant.

A restaurant with a bar area, multiple seating options, and a variety of bottles and glasses on display.

20. Hotel Casona del Colegio

Cartagena Centro, 0.3 km from Santo Domingo Square

Giuseppe

￥37,076

￥37,076 total

Oct 11 - Oct 12

View all properties

Compare popular hotels close to Santo Domingo Square

Property	Star rating	Guest rating
Casa Belle Cartagena Hotel Boutique	10.0 Exceptional 11 reviews	View
Hotel Quadrifolio	10.0 Exceptional 168 reviews	View
Hotel Boutique Casona del Porvenir	9.8 Exceptional 102 reviews	View
Palacio del Agua by Faranda Boutique	9.8 Exceptional 125 reviews	View
Casa La Cartujita	9.8 Exceptional 184 reviews	View

Top Santo Domingo Square Hotel Reviews

Hyatt Regency Cartagena

10/10 Excellent

"Amazing property, it’s well located when it comes to being across the beach and a mall right next door. If you are trying to get to the Historic Center which is where most activities happen you will have to Uber, the favorable thing is that Uber is extremely affordable. I also spent some days at Osh hotel in the Getsemaní area and I would prefer to stay in Hyatt because of the great facility and convenience. The only hiccup we had is that our room was not ready at the check in time @3pm, we waited until 4pm for it. Highly recommend."

Osh Hotel Cartagena

10/10 Excellent

"I really like the stay . The service was nice"

Hotel Casa La Factoria by Faranda Boutique, a member of Radisson Individuals

10/10 Excellent

"Queremos agradecer a todo el personal del hotel por hacer nuestra estadía tan especial. Todos fueron muy atentos, amables, humildes y siempre dispuestos a ayudar en todo lo que necesitábamos. Desde nuestra llegada nos recibieron con una calidez y una hospitalidad increíbles, haciéndonos sentir como en casa. Se nota el cariño y la dedicación que ponen en su trabajo y en atender a cada huésped. ¡Muchas gracias a todo el equipo por hacernos sentir tan bienvenidos y por brindarnos una experiencia tan bonita e inolvidable! Sin duda, nos llevamos muy lindos recuerdos y esperamos regresar. ❤️🇨🇴"

Bastión Luxury Hotel

10/10 Excellent

"Great property in the heart of the old city. Convenienet and walkable to all places within the walled city. The staff were polite and courteous. The breakfast was amazing ."

Sofitel Legend Santa Clara Cartagena

10/10 Excellent

"The hotel was Amazing. All the staff were pleasant,"

Mood Matuna Hotel Cartagena

10/10 Excellent

"The staff were very friendly and helpful"

GHL Collection Armería Real Hotel

8/10 Good

"The room and property were spotless, and every staff member we met was attentive and kind. Breakfast had plenty of good options, and the pool was well kept with great sun for lounging. The room was a bit dark and the magnifying mirror needed replacing, but those were minor. I loved the clothesline in the bathroom, such a thoughtful touch!"

Charleston Santa Teresa Cartagena

10/10 Excellent

"Great hotel, staff and amenities. Rooms are clean and spacious"

Soy Local Centro Historico

10/10 Excellent

"Beautiful"

Other attractions near Santo Domingo Square

Cartagena Cathedral

9.2/10 (3,019 reviews)

After visiting Cartagena Cathedral, make a plan to see the other sights and activities in Cartagena. Amble around the area's beautiful beaches or seek out the local tours.

See properties

Templo de Santo Domingo

Templo de Santo Domingo is just one of the places to see in Cartagena, so why not enjoy the other things to explore during your travels? Stroll along the beautiful beaches or seek out the local tours.

See properties

Botero's Mujer Reclinada

You can learn about the history of Cartagena with a stop at Botero's Mujer Reclinada. Stroll along the beautiful beaches or seek out the local tours.

See properties

Santo Domingo Church and Monastery

After visiting Santo Domingo Church and Monastery, make a plan to see the other sights and activities in Cartagena. Stroll along the beautiful beaches or seek out the local tours.

See properties

Iglesia de Santo Domingo

After visiting Iglesia de Santo Domingo, make a plan to see the other sights and activities in Cartagena. Stroll along the beautiful beaches or seek out the local tours.

See properties

Palace of the Inquisition Cartagena Historical Museum

8.6/10 (69 reviews)

You can browse the exhibits at Palace of the Inquisition Cartagena Historical Museum, a museum with a story of its own, during your trip to Cartagena. Amble around the area's beautiful beaches or seek out the local tours.

See properties

Bolivar Square

9.2/10 (2,207 reviews)

Find out about the history of Cartagena when you spend time at Bolivar Square. Amble around the area's beautiful beaches or seek out the local tours.

See properties

Plaza de Bolívar

Find out about the history of Cartagena when you take a trip to Plaza de Bolívar. Amble around the area's beautiful beaches or seek out the local tours.

See properties

Frequently asked questions

What's the area like around Santo Domingo Square?

Santo Domingo Square is located in a historic area of Cartagena known for its beautiful beaches. If you're looking for a convenient place to stay, check out the 1200 hotels and other accommodations you'll find within a mile.

Where is the best place to stay near Santo Domingo Square?

Adjacent to Santo Domingo Square, Hotel Voilá Centro Histórico is one of the top choices for your stay based on our traveler data, and this hotel offers 2 outdoor pools and 2 bars. Other good choices within a short distance include Mood Matuna Hotel Cartagena and Osh Hotel Cartagena.

How many hotels can I expect to find close to Santo Domingo Square?

Expedia has 1200 hotels and other accommodations within a mile from Santo Domingo Square.

If I need to cancel the hotel reservation for my stay near Santo Domingo Square, will I receive a refund?

Yes! The majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the top deals on offer near Santo Domingo Square.

Where can I learn more about changing or cancelling my trip in the area near Santo Domingo Square?

To access more information about picking new dates or cancelling your stay near Santo Domingo Square, go to https://www.expedia.com/service/.

What can I see and do near Santo Domingo Square?

Study the collections at Palace of the Inquisition Cartagena Historical Museum, Palacio de la Inquisicion, or Cartagena's Gold Museum. Plaza Santo Domingo, San Pedro Claver Church and Convent, and Clock Tower are monuments to see when you're exploring the area around Santo Domingo Square. You can wander around Parque de La Marina, Centenary Park, or La Merced Square if you want a dose of fresh air.

Find hotels near Santo Domingo Square, Cartagena from ￥18,858

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Santo Domingo Square hotels

1. Casa Belle Cartagena Hotel Boutique

2. Hotel Quadrifolio

3. Hotel Boutique Casona del Porvenir

4. Palacio del Agua by Faranda Boutique

5. Casa La Cartujita

6. Hotel Casa San Agustin

7. Privado Designer Boutique Hotel

8. Cinco Quintas Hotel Boutique

9. Four Seasons Hotel & Residences Cartagena

10. Hotel Casa Bianca By Faranda Boutique

11. Casa Claver Loft Boutique Hotel

12. Amarla Boutique Hotel Cartagena

13. Sophia Hotel By OxoHotel

14. Hotel Casa del Gobernador

15. Bastión Luxury Hotel

16. Casa Pestagua Relais Châteaux

17. Upper House

18. GHL Arsenal Hotel

19. Casa del Arzobispado Hotel

20. Hotel Casona del Colegio

Compare popular hotels close to Santo Domingo Square

Top Santo Domingo Square Hotel Reviews

Hyatt Regency Cartagena

Osh Hotel Cartagena

Hotel Casa La Factoria by Faranda Boutique, a member of Radisson Individuals

Bastión Luxury Hotel

Sofitel Legend Santa Clara Cartagena

Mood Matuna Hotel Cartagena

GHL Collection Armería Real Hotel

Charleston Santa Teresa Cartagena

Soy Local Centro Historico

Other attractions near Santo Domingo Square

Cartagena Cathedral

Templo de Santo Domingo

Botero's Mujer Reclinada

Santo Domingo Church and Monastery

Iglesia de Santo Domingo

Palace of the Inquisition Cartagena Historical Museum

Bolivar Square

Plaza de Bolívar

Frequently asked questions