The Best Hotels Closest to Santo Domingo Square in Cartagena for 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Santo Domingo Square hotels

1. Casa Belle Cartagena Hotel Boutique

San Diego, 0.5 km from Santo Domingo Square

Federico

￥32,232

￥32,232 total

Oct 15 - Oct 16

An indoor corridor with arches, a central column, and a dining area with tables and chairs.

A spacious hallway with a wooden staircase, a ceiling fan, and a potted plant with red flowers.

A building with a balcony, arched windows, and a door with a wreath.

A courtyard with a wooden pergola, palm trees, and potted plants.

2. Hotel Quadrifolio

Cartagena Centro, 0.2 km from Santo Domingo Square

Juan Carlos

￥53,033

￥53,033 total

Nov 12 - Nov 13

A spacious indoor area with wicker furniture, a pool, and a brick archway.

A spacious living room with a large sofa, a coffee table, and a chandelier. There is a large painting on the wall and a potted plant in the corner.

A dining area with striped chairs and a wooden table set for a meal.

A rooftop terrace with a white sofa, wicker chairs, and a pool.

3. Casa La Merced by Mustique

San Diego, 0.3 km from Santo Domingo Square

Harry

￥58,187

￥58,187 total

Nov 5 - Nov 6

A courtyard with potted plants, a stone fountain, and a wooden balcony.

A staircase leading to an upper level, with a balcony above. There are potted plants and a table with chairs outside.

A courtyard with potted plants, a stone fountain, and a tree.

A hot tub area with a stone floor, surrounded by potted plants and a yellow wall.

4. Casa Baloco

Cartagena Centro, 0.1 km from Santo Domingo Square

Juan

￥94,374

￥94,374 total

Nov 10 - Nov 11

A modern outdoor pool area with a lounge chair and a small table, surrounded by a geometric patterned fence.

A lobby with a reception desk, a red sofa, and a staircase leading to an outdoor area with plants.

A multi-level atrium with wooden railings, stone columns, and lush greenery.

A restaurant with brick arches, wooden beams, wicker furniture, and a view through a large window.

5. Hotel Boutique Casona del Porvenir

Cartagena Centro, 0.3 km from Santo Domingo Square

Jacqueline

￥29,366

￥29,366 total

Nov 12 - Nov 13

A pool area with stone columns, water features, and outdoor seating.

A breakfast buffet with various food items and condiments.

A corridor with wooden doors, a herringbone floor, a staircase, and a stone wall.

A hotel room with a large bed, a wooden ceiling, a sliding glass door to a bathroom, and a wall-mounted lamp.

6. Palacio del Agua by Faranda Boutique

Cartagena Centro, 0.3 km from Santo Domingo Square

Marycela

￥37,702

￥37,702 total

Nov 11 - Nov 12

A pool area with lounge chairs and a stone wall.

A rooftop terrace with wicker furniture, a table set for dining, and a bell tower in the background.

A room with wicker furniture, a chandelier, and a view of palm trees through large windows.

A bar area with wooden chairs, a counter with bottles, and hanging crystal chandeliers.

7. Hotel Casa San Agustin

Cartagena Centro, 0.3 km from Santo Domingo Square

David

￥85,708

￥85,708 total

Nov 12 - Nov 13

A hotel entrance with a wooden door, a sign reading "Casa la Cartuja," and a white column with a grid-like pattern.

A hallway with a staircase, a wall-mounted planter with various plants, and a tiled wall with a blue mosaic pattern.

A hotel room with a bed, two bedside lamps, a ceiling fan, and a view of a balcony with plants.

A hotel room with a large bed, two bedside tables with lamps, a wall-mounted fan, and a window with curtains.

8. Casa La Cartujita

San Diego, 0.5 km from Santo Domingo Square

Ruben

￥32,253

￥32,253 total

Oct 19 - Oct 20

A hallway with a stone floor, wooden beams, and a large potted plant.

A table set with various dishes, drinks, and a checkered floor.

A hallway with a stone floor, a large potted plant, wall-mounted light fixtures, and a decorative wall piece.

A balcony with a railing, a potted plant, and a building with a tiled roof in the background.

9. Privado Designer Boutique Hotel

San Diego, 0.5 km from Santo Domingo Square

Katherine

￥21,881

￥21,881 total

Oct 25 - Oct 26

A grand lobby with a central seating area, a staircase, and a large plant.

A grand hallway with high ceilings, ornate columns, and a large chandelier.

A man and a woman relaxing on a striped floating platform in a clear pool.

10. Four Seasons Hotel & Residences Cartagena

Getsemani, 0.6 km from Santo Domingo Square

john

￥83,904

￥83,904 total

Oct 18 - Oct 19

A pool area with a stone wall, hanging plants, and a lantern.

A bedroom with two beds, each with a canopy, and a sofa.

A table set for dining with a candle, glasses, and a hat.

A spacious living room with a sofa set, a coffee table, and a chandelier.

11. Casa De Alba Hotel Boutique

Cartagena Centro, 0.1 km from Santo Domingo Square

Christian

￥34,740

￥34,740 total

Oct 19 - Oct 20

A swimming pool with a tiled deck, surrounded by lush greenery and a building with a balcony.

A multi-story building with a classic architectural style, featuring a central entrance with a dark door, multiple windows on each floor, and decorative ironwork.

A historic building with multiple stories, large windows, and a balcony.

A spacious indoor courtyard with a central palm tree, surrounded by various plants and a stone staircase leading to an upper level.

12. Cinco Quintas Hotel Boutique

Cartagena Centro, 0.3 km from Santo Domingo Square

Fernando

￥40,205

￥40,205 total

Oct 14 - Oct 15

A hotel room with a large bed, a seating area with cushions, a view of a tower, and a balcony with a railing.

A modern living room with a flat-screen TV, sofas, a coffee table, and a large window offering a city view.

A spacious room with a ceiling fan, a large flat-screen TV, a wooden cabinet, a sofa, and a view through large glass doors.

A hotel room with two beds, a small table, a nightstand, a lamp, and a view of greenery through a window.

13. Hotel Casa Bianca By Faranda Boutique

Cartagena Walled City, 0.4 km from Santo Domingo Square

"We had an amazing stay! The hotel was clean, comfortable, and had everything we needed. Santiago was absolutely wonderful and made us feel very welcome. The young lady assisting with the breakfast service was also amazing and provided such friendly, helpful service. We took full advantage of the breakfast and pool, and both were great. Overall, we really enjoyed our stay and honestly wish we could pick this hotel up and move it around with us whenever we travel so it would always be available!...

Gesemia

￥28,283

￥28,283 total

Nov 11 - Nov 12

A spiral staircase with a central planter, a small table with a chair, and a railing.

A barista preparing a drink at a counter with a view of an outdoor pool and a staircase.

A bedroom with a bed, a TV, a sofa, and a dining area.

14. Casa Carolina Luxury Wellness Hotel

Cartagena Centro, 0.2 km from Santo Domingo Square

Richard David

￥53,649

￥53,649 total

Nov 10 - Nov 11

A rooftop pool area with lounge seating, a pool, and a view of a historic building.

A restaurant with checkered flooring, tables set with wine glasses, and a wall-mounted menu board.

A hotel room with a bed, a television, a wooden wardrobe, and a wicker chair.

15. Sophia Hotel By OxoHotel

Cartagena Centro, 0.3 km from Santo Domingo Square

Anthony

￥49,346

￥49,346 total

Nov 11 - Nov 12

A cozy living room with a white sofa, a wicker bench, a coffee table with a bowl of nuts, and a large mirror reflecting the room.

A restaurant with a long wooden table, wicker chairs, hanging lights, and a stone wall.

A pool area with a view of a church tower, surrounded by palm trees and outdoor seating.

A restaurant with a checkered floor, wooden tables, and hanging plants.

16. Amarla Boutique Hotel Cartagena

Cartagena Centro, 0.1 km from Santo Domingo Square

Matt

￥46,964

￥46,964 total

Oct 21 - Oct 22

A dining table with a plate of food, a glass vase with flowers, and a woven placemat.

A person sitting by a window with a laptop and a bowl, overlooking a building and greenery.

A room with a stone wall, a sofa, a chair, a table with a candle, and hanging lights.

17. Casa Noa Colonial Rooms

Cartagena Centro, 0.3 km from Santo Domingo Square

SAMER

￥10,589

￥10,589 total

Oct 14 - Oct 15

A swimming pool with clear water, surrounded by lush greenery and flowering plants.

A spacious indoor area with a dining table and chairs, a sofa, and a lamp.

An outdoor seating area with tables and chairs, a stone wall, and a tree providing shade.

A building with a white facade, wooden window bars, and a sign that reads "Bastion."

18. Bastión Luxury Hotel

San Diego, 0.4 km from Santo Domingo Square

Santiago

￥58,372

￥58,372 total

Nov 12 - Nov 13

A swimming pool with a view of historic buildings, including a church with a dome and bell tower.

A hallway with a wooden ceiling, a large potted plant, and hanging vines.

A balcony with pink flowers, a person holding a drink, and buildings in the background.

A modern bedroom with a large bed, a sofa, and a balcony with plants.

19. Casa Claver Loft Boutique Hotel

Cartagena Centro, 0.2 km from Santo Domingo Square

Kevin

￥39,500

￥39,500 total

Nov 13 - Nov 14

A courtyard with two lounge chairs, a brick wall, and a tiled roof.

A building with a balcony, arched doorways, and flags.

A cozy dining area with a marble table, cushioned chairs, and a chandelier.

An outdoor swimming pool with lounge chairs and umbrellas, surrounded by a patio area with tables and chairs.

20. Hotel Casa del Gobernador

Cartagena Centro, 0.2 km from Santo Domingo Square

Peyton

￥52,417

￥52,417 total

Nov 12 - Nov 13

View all properties

Compare popular hotels close to Santo Domingo Square

Property	Star rating	Guest rating
Casa Belle Cartagena Hotel Boutique	10.0 Exceptional 11 reviews	View
Hotel Quadrifolio	10.0 Exceptional 169 reviews	View
Casa La Merced by Mustique	10.0 Exceptional 37 reviews	View
Casa Baloco	10.0 Exceptional 10 reviews	View
Hotel Boutique Casona del Porvenir	9.8 Exceptional 103 reviews	View

Top Santo Domingo Square Hotel Reviews

OZ Hotel Collection

10/10 Excellent

"Awesome place"

Osh Hotel Cartagena

10/10 Excellent

"We absolutely loved our stay! The hotel’s aesthetic was beautiful, and you can tell so much thought went into the details. Everything was incredibly clean, the breakfast was delicious, and the Le Labo bath products were such a nice touch! The staff was welcoming, attentive, and provided excellent service throughout our stay. Overall, such a lovely experience and definitely a hotel we would recommend to anyone visiting Cartagena!"

Hyatt Regency Cartagena

10/10 Excellent

"Hyatt hotel was very clean and all the staff were very welcome"

Hotel Casa La Mantilla by Faranda Boutique

10/10 Excellent

"Love this hotel. Super cute boutique hotel. Everyone was super nice. They have a little pool and both times we used it we were the only ones there. The staff is great and everyone was super kind. It is walking distance to all things in the walled city and Getsamani. Oh and the air conditioning was amazing in the room! 100% would stay again."

Hotel Casa La Factoria by Faranda Boutique, a member of Radisson Individuals

10/10 Excellent

"Queremos agradecer a todo el personal del hotel por hacer nuestra estadía tan especial. Todos fueron muy atentos, amables, humildes y siempre dispuestos a ayudar en todo lo que necesitábamos. Desde nuestra llegada nos recibieron con una calidez y una hospitalidad increíbles, haciéndonos sentir como en casa. Se nota el cariño y la dedicación que ponen en su trabajo y en atender a cada huésped. ¡Muchas gracias a todo el equipo por hacernos sentir tan bienvenidos y por brindarnos una experiencia tan bonita e inolvidable! Sin duda, nos llevamos muy lindos recuerdos y esperamos regresar. ❤️🇨🇴"

Bastión Luxury Hotel

10/10 Excellent

"Great property in the heart of the old city. Convenienet and walkable to all places within the walled city. The staff were polite and courteous. The breakfast was amazing ."

Mood Matuna Hotel Cartagena

10/10 Excellent

"The staff were very friendly and helpful"

GHL Collection Armería Real Hotel

8/10 Good

"The room and property were spotless, and every staff member we met was attentive and kind. Breakfast had plenty of good options, and the pool was well kept with great sun for lounging. The room was a bit dark and the magnifying mirror needed replacing, but those were minor. I loved the clothesline in the bathroom, such a thoughtful touch!"

Charleston Santa Teresa Cartagena

10/10 Excellent

"Great hotel, staff and amenities. Rooms are clean and spacious"

Other attractions near Santo Domingo Square

Cartagena Cathedral

9.2/10 (3,019 reviews)

After visiting Cartagena Cathedral, make a plan to see the other sights and activities in Cartagena. Amble around the area's beautiful beaches or seek out the local tours.

See properties

Templo de Santo Domingo

Templo de Santo Domingo is just one of the places to see in Cartagena, so why not enjoy the other things to explore during your travels? Stroll along the beautiful beaches or seek out the local tours.

See properties

Botero's Mujer Reclinada

You can learn about the history of Cartagena with a stop at Botero's Mujer Reclinada. Stroll along the beautiful beaches or seek out the local tours.

See properties

Santo Domingo Church and Monastery

After visiting Santo Domingo Church and Monastery, make a plan to see the other sights and activities in Cartagena. Stroll along the beautiful beaches or seek out the local tours.

See properties

Iglesia de Santo Domingo

After visiting Iglesia de Santo Domingo, make a plan to see the other sights and activities in Cartagena. Stroll along the beautiful beaches or seek out the local tours.

See properties

Palace of the Inquisition Cartagena Historical Museum

8.6/10 (69 reviews)

You can browse the exhibits at Palace of the Inquisition Cartagena Historical Museum, a museum with a story of its own, during your trip to Cartagena. Amble around the area's beautiful beaches or seek out the local tours.

See properties

Bolivar Square

9.2/10 (2,207 reviews)

Find out about the history of Cartagena when you spend time at Bolivar Square. Amble around the area's beautiful beaches or seek out the local tours.

See properties

Cathedral of Saint Catherine of Alexandria

After visiting Cathedral of Saint Catherine of Alexandria, make a plan to see the other sights and activities in Cartagena. Discover the area's top-notch restaurants or seek out the local tours.

See properties

Frequently asked questions

What's the area like around Santo Domingo Square?

Santo Domingo Square is located in a historic area of Cartagena known for its beautiful beaches. If you're looking for a convenient place to stay, check out the 1200 hotels and other accommodations you'll find within a mile.

Where is the best place to stay near Santo Domingo Square?

Adjacent to Santo Domingo Square, Hotel Voilá Centro Histórico is one of the top choices for your stay based on our traveler data, and this hotel offers 2 outdoor pools and 2 bars. Other good choices within a short distance include Mood Matuna Hotel Cartagena and Osh Hotel Cartagena.

How many hotels can I expect to find close to Santo Domingo Square?

Expedia has 1200 hotels and other accommodations within a mile from Santo Domingo Square.

If I need to cancel the hotel reservation for my stay near Santo Domingo Square, will I receive a refund?

Yes! The majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the top deals on offer near Santo Domingo Square.

Where can I learn more about changing or cancelling my trip in the area near Santo Domingo Square?

To access more information about picking new dates or cancelling your stay near Santo Domingo Square, go to https://www.expedia.com/service/.

What can I see and do near Santo Domingo Square?

Study the collections at Palace of the Inquisition Cartagena Historical Museum, Palacio de la Inquisicion, or Cartagena's Gold Museum. Plaza Santo Domingo, San Pedro Claver Church and Convent, and Clock Tower are monuments to see when you're exploring the area around Santo Domingo Square. You can wander around Parque de La Marina, Centenary Park, or La Merced Square if you want a dose of fresh air.

Find hotels near Santo Domingo Square, Cartagena from ￥10,589

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Santo Domingo Square hotels

1. Casa Belle Cartagena Hotel Boutique

2. Hotel Quadrifolio

3. Casa La Merced by Mustique

4. Casa Baloco

5. Hotel Boutique Casona del Porvenir

6. Palacio del Agua by Faranda Boutique

7. Hotel Casa San Agustin

8. Casa La Cartujita

9. Privado Designer Boutique Hotel

10. Four Seasons Hotel & Residences Cartagena

11. Casa De Alba Hotel Boutique

12. Cinco Quintas Hotel Boutique

13. Hotel Casa Bianca By Faranda Boutique

14. Casa Carolina Luxury Wellness Hotel

15. Sophia Hotel By OxoHotel

16. Amarla Boutique Hotel Cartagena

17. Casa Noa Colonial Rooms

18. Bastión Luxury Hotel

19. Casa Claver Loft Boutique Hotel

20. Hotel Casa del Gobernador

Compare popular hotels close to Santo Domingo Square

Top Santo Domingo Square Hotel Reviews

OZ Hotel Collection

Osh Hotel Cartagena

Hyatt Regency Cartagena

Hotel Casa La Mantilla by Faranda Boutique

Hotel Casa La Factoria by Faranda Boutique, a member of Radisson Individuals

Bastión Luxury Hotel

Mood Matuna Hotel Cartagena

GHL Collection Armería Real Hotel

Charleston Santa Teresa Cartagena

Other attractions near Santo Domingo Square

Cartagena Cathedral

Templo de Santo Domingo

Botero's Mujer Reclinada

Santo Domingo Church and Monastery

Iglesia de Santo Domingo

Palace of the Inquisition Cartagena Historical Museum

Bolivar Square

Cathedral of Saint Catherine of Alexandria

Frequently asked questions