The Best Hotels Closest to Santo Domingo Square in Cartagena for 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Santo Domingo Square hotels

1. Casa Belle Cartagena Hotel Boutique

San Diego, 0.5 km from Santo Domingo Square

Federico

￥32,680

￥32,680 total

Oct 26 - Oct 27

An indoor corridor with arches, a central column, and a dining area with tables and chairs.

A spacious hallway with a wooden staircase, a ceiling fan, and a potted plant with red flowers.

An indoor swimming pool with tiled walls and a wooden floor, surrounded by lush green plants and a white building with wooden window frames.

A building with a balcony, arched windows, and a door with a wreath.

2. Hotel Quadrifolio

Cartagena Centro, 0.2 km from Santo Domingo Square

Juan Carlos

￥55,505

￥55,505 total

Nov 21 - Nov 22

A spacious indoor area with wicker furniture, a pool, and a brick archway.

A dining area with striped chairs and a wooden table set for a meal.

A spacious indoor area with wicker furniture, a pool, and potted plants.

A rooftop terrace with a white sofa, wicker chairs, and a pool.

3. Casa La Merced by Mustique

San Diego, 0.3 km from Santo Domingo Square

Harry

￥57,846

￥57,846 total

Oct 26 - Oct 27

A courtyard with potted plants, a stone fountain, and a wooden balcony.

A room with a bed, two rocking chairs, a small table with books, a lamp, and a ceiling fan.

A courtyard with potted plants, a stone fountain, and a tree.

A hot tub area with a stone floor, surrounded by potted plants and a yellow wall.

4. Casa Baloco

Cartagena Centro, 0.1 km from Santo Domingo Square

Juan

￥79,847

￥79,847 total

Nov 22 - Nov 23

A hallway with a stone floor, wooden beams, and a large potted plant.

A hallway with a stone floor, a large potted plant, wall-mounted light fixtures, and a decorative wall piece.

A courtyard with a tiled floor, a small pool, and a balcony with wooden railings.

A balcony with a railing, a potted plant, and a building with a tiled roof in the background.

5. Privado Designer Boutique Hotel

San Diego, 0.5 km from Santo Domingo Square

Katherine

￥20,585

￥20,585 total

Oct 26 - Oct 27

A modern outdoor pool area with a lounge chair and a small table, surrounded by a geometric patterned fence.

A modern hotel room with a large bed, a wooden headboard, a wall-mounted air conditioner, a small desk with a chair, and a decorative plant.

A lobby with a reception desk, a red sofa, and a staircase leading to an outdoor area with plants.

A multi-level atrium with wooden railings, stone columns, and lush greenery.

6. Hotel Boutique Casona del Porvenir

Cartagena Centro, 0.3 km from Santo Domingo Square

Jacqueline

￥31,231

￥31,231 total

Nov 23 - Nov 24

A pool area with stone columns, water features, and outdoor seating.

A breakfast buffet with various food items and condiments.

A courtyard with a pool, wooden furniture, and a dining area.

A hotel room with a large bed, a wooden ceiling, a sliding glass door to a bathroom, and a wall-mounted lamp.

7. Palacio del Agua by Faranda Boutique

Cartagena Centro, 0.3 km from Santo Domingo Square

Marycela

￥31,227

￥31,227 total

Oct 26 - Oct 27

A grand lobby with a central seating area, a staircase, and a large plant.

A man and a woman relaxing on a striped floating platform in a clear pool.

A multi-story building with a courtyard featuring palm trees and a pool.

8. Four Seasons Hotel & Residences Cartagena

Getsemani, 0.6 km from Santo Domingo Square

Jaime

￥89,336

￥89,336 total

Oct 25 - Oct 26

A wicker swing chair with ropes, a stone pillar, and a seating area with cushions.

A barista preparing a drink at a counter with a view of an outdoor pool and a staircase.

A spiral staircase with a central planter, a small table with a chair, and a railing.

9. Casa Carolina Luxury Wellness Hotel

Cartagena Centro, 0.2 km from Santo Domingo Square

Richard David

￥53,334

￥53,334 total

Oct 25 - Oct 26

A cozy living room with a white sofa, a wicker bench, a coffee table with a bowl of nuts, and a large mirror reflecting the room.

A rustic indoor garden with a water feature, brick pathway, and lush greenery.

A restaurant with a long wooden table, wicker chairs, hanging lights, and a stone wall.

A pool area with a view of a church tower, surrounded by palm trees and outdoor seating.

10. Amarla Boutique Hotel Cartagena

Cartagena Centro, 0.1 km from Santo Domingo Square

Matt

￥42,891

￥42,891 total

Oct 24 - Oct 25

A rooftop pool area with lounge seating, a pool, and a view of a historic building.

A restaurant with checkered flooring, tables set with wine glasses, and a wall-mounted menu board.

A hotel room with a bed, a television, a wooden wardrobe, and a wicker chair.

11. Sophia Hotel By OxoHotel

Cartagena Centro, 0.3 km from Santo Domingo Square

Anthony

￥35,856

￥35,856 total

Oct 24 - Oct 25

A hotel with a pool, outdoor seating, and a view of the ocean.

A hotel patio with outdoor seating, a bar, and a staircase leading to an upper level.

A spacious living area with a high ceiling, a central island, and a view of the outdoors through large windows.

A banquet hall with tiered seating, chandeliers, and floral arrangements.

12. Sofitel Legend Santa Clara Cartagena

San Diego, 0.6 km from Santo Domingo Square

Jaime

￥68,256

￥68,256 total

Oct 26 - Oct 27

A swimming pool with clear water, surrounded by lush greenery and flowering plants.

A building with a white facade, wooden window bars, and a sign that reads "Bastion."

An outdoor seating area with tables and chairs, a stone wall, and a tree providing shade.

A spacious atrium with a central seating area, large windows, and a reflective floor.

13. Bastión Luxury Hotel

San Diego, 0.4 km from Santo Domingo Square

Santiago

￥60,423

￥60,423 total

Oct 29 - Oct 30

A pool area with arched structures and a wooden deck.

A spacious living room with a white sofa, a wooden chair, a coffee table, and a large window with a view.

A room with a bed, a wooden partition, and a view through a window with shutters.

A wooden door with glass panels leading to an outdoor area with a stone wall and greenery.

14. Casa Trujillo Cartagena

Cartagena Centro, 0.1 km from Santo Domingo Square

Gina

￥33,093

￥33,093 total

Oct 26 - Oct 27

An outdoor dining area with tables and chairs, palm trees, and a view of a cityscape at dusk.

A poolside view with a city skyline in the background.

A spacious room with a large wooden bookshelf, a flat-screen TV, and a large glass door with a view of the outside.

A two-story building with a white facade, large windows with blue shutters, and a wooden entrance door.

15. GHL Arsenal Hotel

Getsemani, 0.6 km from Santo Domingo Square

Shayna

￥18,991

￥18,991 total

Nov 23 - Nov 24

A person in a swimming pool with a table in the foreground holding drinks and a pineapple.

A bartender pouring drinks into glasses at a bar.

A modern living room with a sofa, coffee table, and a painting on the wall.

A room with a large window, a leather sofa, a wooden chair, and a glass table.

16. Townhouse Boutique Hotel

Cartagena Walled City, 0.4 km from Santo Domingo Square

Samer

￥23,633

￥23,633 total

Nov 23 - Nov 24

A dining area with a glass table set for four, surrounded by wicker chairs, with a pool and a building in the background.

A spiral staircase with a stone finish, surrounded by white walls and potted plants.

A bedroom with a large bed, a stone wall, and a wooden ceiling.

17. Upper House

Cartagena Walled City, 0.5 km from Santo Domingo Square

Dallas

￥15,629

￥15,785 total

Oct 25 - Oct 26

A dining table with a plate of food, a glass vase with flowers, and a woven placemat.

A room with a stone wall, a sofa, a chair, a table with a candle, and hanging lights.

A person sitting by a window with a laptop and a bowl, overlooking a building and greenery.

18. Casa Noa Colonial Rooms

Cartagena Centro, 0.3 km from Santo Domingo Square

Jose P

￥10,527

￥10,527 total

Oct 24 - Oct 25

A rooftop terrace with a hot tub, potted plants, and a view of historic buildings.

A reception area with a wooden reception desk, a wall-mounted air conditioner, and a closed door.

A hotel room with a large bed, a view of a cityscape, a painting of palm trees, and a bathtub.

A tall, modern building with a prominent corner entrance and multiple windows.

19. Terrazas Hotel Boutique

La Matuna, 0.5 km from Santo Domingo Square

Jorge Mario

￥29,381

￥29,381 total

Oct 27 - Oct 28

A white building with wooden doors and windows, a balcony with hanging plants, and a sign indicating it is a hotel.

A rooftop pool area with a staircase leading down to a lounge area.

A bedroom with a bed, a ceiling fan, a window with shutters, a framed picture on the wall, and a bedside table with a lamp.

A bicycle with a basket containing fruits, parked on a tiled floor.

20. Casa Quero Hotel Boutique

Cartagena Walled City, 0.6 km from Santo Domingo Square

Tomas

￥22,001

￥22,001 total

Oct 26 - Oct 27

View all properties

Compare popular hotels close to Santo Domingo Square

Property	Star rating	Guest rating
Casa Belle Cartagena Hotel Boutique	10.0 Exceptional 11 reviews	View
Hotel Quadrifolio	10.0 Exceptional 170 reviews	View
Casa La Merced by Mustique	10.0 Exceptional 38 reviews	View
Casa Baloco	10.0 Exceptional 10 reviews	View
Privado Designer Boutique Hotel	9.8 Exceptional 191 reviews	View

Top Santo Domingo Square Hotel Reviews

OZ Hotel Collection

10/10 Excellent

"Na"

Hotel Casa San Agustin

10/10 Excellent

"Un ligar para volver, excelente"

Estelar Cartagena de Indias Hotel

10/10 Excellent

"I"

Osh Hotel Cartagena

8/10 Good

"OSH Hotel is worth traveling to if you’re looking for a beautiful boutique hotel. The on-site bar and restaurant was convenient, and the location of the hotel is in the heart of the city—which made exploring the city easily accessible. Also, the staff were friendly and helpful. The only thing stopping me from giving them 5 stars was the cuisine. The menu was well-rounded but their dishes lacked flavor; which was surprising given the fact that Cartagena is full of flavor and great dining. All in all, I enjoyed my stay!"

Casa Noa Colonial Rooms

10/10 Excellent

"ubicacion perfecta, buenas condiciones, limpio, excelente estadía"

Bastión Luxury Hotel

8/10 Good

"Great location, great service, they just need to improve the breakfast and the elevator was very slow and not working few times."

Mood Matuna Hotel Cartagena

10/10 Excellent

"The room was very warm and inviting. We booked the suite with private pool. The view was beautiful and even though there was a lot of activity on the street, the room was quiet. We loved that the hotel was walking distance to the walled city and many restaurants and nightlife. The restaurant is under construction so we didn’t take advantage of the food services, but that did not impact our stay. We would stay here again."

Four Seasons Hotel & Residences Cartagena

10/10 Excellent

"The hotel and staff were great."

GHL Collection Armería Real Hotel

8/10 Good

"The room and property were spotless, and every staff member we met was attentive and kind. Breakfast had plenty of good options, and the pool was well kept with great sun for lounging. The room was a bit dark and the magnifying mirror needed replacing, but those were minor. I loved the clothesline in the bathroom, such a thoughtful touch!"

Other attractions near Santo Domingo Square

Cartagena Cathedral

9.2/10 (3,019 reviews)

After visiting Cartagena Cathedral, make a plan to see the other sights and activities in Cartagena. Amble around the area's beautiful beaches or seek out the local tours.

See properties

Templo de Santo Domingo

Templo de Santo Domingo is just one of the places to see in Cartagena, so why not enjoy the other things to explore during your travels? Stroll along the beautiful beaches or seek out the local tours.

See properties

Botero's Mujer Reclinada

You can learn about the history of Cartagena with a stop at Botero's Mujer Reclinada. Stroll along the beautiful beaches or seek out the local tours.

See properties

Santo Domingo Church and Monastery

After visiting Santo Domingo Church and Monastery, make a plan to see the other sights and activities in Cartagena. Stroll along the beautiful beaches or seek out the local tours.

See properties

Iglesia de Santo Domingo

After visiting Iglesia de Santo Domingo, make a plan to see the other sights and activities in Cartagena. Stroll along the beautiful beaches or seek out the local tours.

See properties

Palace of the Inquisition Cartagena Historical Museum

8.6/10 (69 reviews)

You can browse the exhibits at Palace of the Inquisition Cartagena Historical Museum, a museum with a story of its own, during your trip to Cartagena. Amble around the area's beautiful beaches or seek out the local tours.

See properties

Bolivar Square

9.2/10 (2,207 reviews)

Find out about the history of Cartagena when you spend time at Bolivar Square. Amble around the area's beautiful beaches or seek out the local tours.

See properties

Cathedral of Saint Catherine of Alexandria

After visiting Cathedral of Saint Catherine of Alexandria, make a plan to see the other sights and activities in Cartagena. Discover the area's top-notch restaurants or seek out the local tours.

See properties

Frequently asked questions

What's the area like around Santo Domingo Square?

Santo Domingo Square is located in a historic area of Cartagena known for its beautiful beaches. If you're looking for a convenient place to stay, check out the 1200 hotels and other accommodations you'll find within a mile.

Where is the best place to stay near Santo Domingo Square?

Adjacent to Santo Domingo Square, Hotel Voilá Centro Histórico is one of the top choices for your stay based on our traveler data, and this hotel offers 2 outdoor pools and 2 bars. Other good choices within a short distance include Mood Matuna Hotel Cartagena and Osh Hotel Cartagena.

How many hotels can I expect to find close to Santo Domingo Square?

Expedia has 1200 hotels and other accommodations within a mile from Santo Domingo Square.

If I need to cancel the hotel reservation for my stay near Santo Domingo Square, will I receive a refund?

Yes! The majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the top deals on offer near Santo Domingo Square.

Where can I learn more about changing or cancelling my trip in the area near Santo Domingo Square?

To access more information about picking new dates or cancelling your stay near Santo Domingo Square, go to https://www.expedia.com/service/.

What can I see and do near Santo Domingo Square?

Study the collections at Palace of the Inquisition Cartagena Historical Museum, Palacio de la Inquisicion, or Cartagena's Gold Museum. Plaza Santo Domingo, San Pedro Claver Church and Convent, and Clock Tower are monuments to see when you're exploring the area around Santo Domingo Square. You can wander around Parque de La Marina, Centenary Park, or La Merced Square if you want a dose of fresh air.

Find hotels near Santo Domingo Square, Cartagena from ￥10,527

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Santo Domingo Square hotels

1. Casa Belle Cartagena Hotel Boutique

2. Hotel Quadrifolio

3. Casa La Merced by Mustique

4. Casa Baloco

5. Privado Designer Boutique Hotel

6. Hotel Boutique Casona del Porvenir

7. Palacio del Agua by Faranda Boutique

8. Four Seasons Hotel & Residences Cartagena

9. Casa Carolina Luxury Wellness Hotel

10. Amarla Boutique Hotel Cartagena

11. Sophia Hotel By OxoHotel

12. Sofitel Legend Santa Clara Cartagena

13. Bastión Luxury Hotel

14. Casa Trujillo Cartagena

15. GHL Arsenal Hotel

16. Townhouse Boutique Hotel

17. Upper House

18. Casa Noa Colonial Rooms

19. Terrazas Hotel Boutique

20. Casa Quero Hotel Boutique

Compare popular hotels close to Santo Domingo Square

Top Santo Domingo Square Hotel Reviews

OZ Hotel Collection

Hotel Casa San Agustin

Estelar Cartagena de Indias Hotel

Osh Hotel Cartagena

Casa Noa Colonial Rooms

Bastión Luxury Hotel

Mood Matuna Hotel Cartagena

Four Seasons Hotel & Residences Cartagena

GHL Collection Armería Real Hotel

Other attractions near Santo Domingo Square

Cartagena Cathedral

Templo de Santo Domingo

Botero's Mujer Reclinada

Santo Domingo Church and Monastery

Iglesia de Santo Domingo

Palace of the Inquisition Cartagena Historical Museum

Bolivar Square

Cathedral of Saint Catherine of Alexandria

Frequently asked questions