The Best Hotels Closest to Santo Domingo Square in Cartagena for 2026

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Our top choices for Santo Domingo Square hotels

1. Casa Belle Cartagena Hotel Boutique

San Diego, 0.5 km from Santo Domingo Square

Federico

￥32,809

￥32,809 total

Oct 22 - Oct 23

An indoor corridor with arches, a central column, and a dining area with tables and chairs.

A spacious hallway with a wooden staircase, a ceiling fan, and a potted plant with red flowers.

An indoor swimming pool with tiled walls and a wooden floor, surrounded by lush green plants and a white building with wooden window frames.

A building with a balcony, arched windows, and a door with a wreath.

2. Hotel Quadrifolio

Cartagena Centro, 0.2 km from Santo Domingo Square

Juan Carlos

￥55,997

￥55,997 total

Nov 16 - Nov 17

A spacious indoor area with wicker furniture, a pool, and a brick archway.

A rooftop terrace with a white sofa, wicker chairs, and a pool.

A dining area with striped chairs and a wooden table set for a meal.

A spacious indoor area with wicker furniture, a pool, and potted plants.

3. Casa La Merced by Mustique

San Diego, 0.3 km from Santo Domingo Square

Harry

￥58,358

￥58,358 total

Oct 19 - Oct 20

A modern outdoor pool area with a lounge chair and a small table, surrounded by a geometric patterned fence.

A lobby with a reception desk, a red sofa, and a staircase leading to an outdoor area with plants.

A modern hotel room with a large bed, a wooden headboard, a wall-mounted air conditioner, a small desk with a chair, and a decorative plant.

A restaurant with brick arches, wooden beams, wicker furniture, and a view through a large window.

4. Hotel Boutique Casona del Porvenir

Cartagena Centro, 0.3 km from Santo Domingo Square

Jacqueline

￥29,109

￥29,109 total

Nov 18 - Nov 19

A pool area with stone columns, water features, and outdoor seating.

A courtyard with a pool, wooden furniture, and a dining area.

A breakfast buffet with various food items and condiments.

A corridor with wooden doors, a herringbone floor, a staircase, and a stone wall.

5. Palacio del Agua by Faranda Boutique

Cartagena Centro, 0.3 km from Santo Domingo Square

Marycela

￥35,078

￥35,078 total

Oct 26 - Oct 27

A swimming pool with a view of historic buildings, including a church with a dome and bell tower.

A modern bedroom with a large bed, a sofa, and a balcony with plants.

A modern living room with a white coffee table, two sofas, a dining area with a table and chairs, and a large window with blinds.

A balcony with pink flowers, a person holding a drink, and buildings in the background.

6. Casa Claver Loft Boutique Hotel

Cartagena Centro, 0.2 km from Santo Domingo Square

Kevin

￥38,382

￥38,382 total

Oct 19 - Oct 20

A pool area with lounge chairs and a stone wall.

A bar area with wooden chairs, a counter with bottles, and hanging crystal chandeliers.

A rooftop terrace with wicker furniture, a table set for dining, and a bell tower in the background.

A dining area with a chandelier, wooden ceiling, and tables set for dining.

7. Hotel Casa San Agustin

Cartagena Centro, 0.3 km from Santo Domingo Square

David

￥86,354

￥86,354 total

Nov 18 - Nov 19

A hotel room with a large bed, a seating area with cushions, a view of a tower, and a balcony with a railing.

A modern living room with a flat-screen TV, sofas, a coffee table, and a large window offering a city view.

A spacious room with a ceiling fan, a large flat-screen TV, a wooden cabinet, a sofa, and a view through large glass doors.

A hotel room with two beds, a small table, a nightstand, a lamp, and a view of greenery through a window.

8. Hotel Casa Bianca By Faranda Boutique

Cartagena Walled City, 0.4 km from Santo Domingo Square

"We had an amazing stay! The hotel was clean, comfortable, and had everything we needed. Santiago was absolutely wonderful and made us feel very welcome. The young lady assisting with the breakfast service was also amazing and provided such friendly, helpful service. We took full advantage of the breakfast and pool, and both were great. Overall, we really enjoyed our stay and honestly wish we could pick this hotel up and move it around with us whenever we travel so it would always be available!...

Gesemia

￥24,343

￥24,343 total

Oct 26 - Oct 27

A grand lobby with a central seating area, a staircase, and a large plant.

A multi-story building with a courtyard featuring palm trees and a pool.

A man and a woman relaxing on a striped floating platform in a clear pool.

9. Four Seasons Hotel & Residences Cartagena

Getsemani, 0.6 km from Santo Domingo Square

Jaime

￥90,071

￥90,071 total

Oct 25 - Oct 26

A spiral staircase with a central planter, a small table with a chair, and a railing.

A bedroom with a bed, a TV, a sofa, and a dining area.

A barista preparing a drink at a counter with a view of an outdoor pool and a staircase.

10. Casa Carolina Luxury Wellness Hotel

Cartagena Centro, 0.2 km from Santo Domingo Square

Richard David

￥48,403

￥48,403 total

Oct 19 - Oct 20

A cozy living room with a white sofa, a wicker bench, a coffee table with a bowl of nuts, and a large mirror reflecting the room.

A pool area with a view of a church tower, surrounded by palm trees and outdoor seating.

A restaurant with a checkered floor, wooden tables, and hanging plants.

A restaurant with a long wooden table, wicker chairs, hanging lights, and a stone wall.

11. Amarla Boutique Hotel Cartagena

Cartagena Centro, 0.1 km from Santo Domingo Square

Matt

￥47,111

￥47,111 total

Oct 21 - Oct 22

A hallway with a stone floor, wooden beams, and a large potted plant.

A hallway with a stone floor, a large potted plant, wall-mounted light fixtures, and a decorative wall piece.

A balcony with a railing, a potted plant, and a building with a tiled roof in the background.

A table set with various dishes, drinks, and a checkered floor.

12. Privado Designer Boutique Hotel

San Diego, 0.5 km from Santo Domingo Square

Katherine

￥18,506

￥18,506 total

Oct 19 - Oct 20

A swimming pool with a tiled deck, surrounded by lush greenery and a building with a balcony.

A spacious indoor courtyard with a central palm tree, surrounded by various plants and a stone staircase leading to an upper level.

A multi-story building with a classic architectural style, featuring a central entrance with a dark door, multiple windows on each floor, and decorative ironwork.

A spacious lobby with a high ceiling, a central staircase, and a decorative wooden fence.

13. Cinco Quintas Hotel Boutique

Cartagena Centro, 0.3 km from Santo Domingo Square

Fernando

￥40,330

￥40,330 total

Oct 19 - Oct 20

A rooftop pool area with lounge seating, a pool, and a view of a historic building.

A restaurant with checkered flooring, tables set with wine glasses, and a wall-mounted menu board.

An outdoor seating area with a sofa, chairs, and a large umbrella.

14. Sophia Hotel By OxoHotel

Cartagena Centro, 0.3 km from Santo Domingo Square

Anthony

￥40,590

￥40,590 total

Nov 11 - Nov 12

A courtyard with two lounge chairs, a brick wall, and a tiled roof.

A building with a balcony, arched doorways, and flags.

An outdoor swimming pool with lounge chairs and umbrellas, surrounded by a patio area with tables and chairs.

A spacious living area with a dining table, chairs, a sofa, and a patterned rug.

15. Hotel Casa del Gobernador

Cartagena Centro, 0.2 km from Santo Domingo Square

Peyton

￥39,834

￥39,834 total

Oct 23 - Oct 24

A swimming pool with clear water, surrounded by lush greenery and flowering plants.

A spacious atrium with a central seating area, large windows, and a reflective floor.

A spacious indoor area with a dining table and chairs, a sofa, and a lamp.

A building with a white facade, wooden window bars, and a sign that reads "Bastion."

16. Bastión Luxury Hotel

San Diego, 0.4 km from Santo Domingo Square

Santiago

￥60,958

￥60,958 total

Oct 29 - Oct 30

A pool area with arched structures and a wooden deck.

A wooden door with glass panels leading to an outdoor area with a stone wall and greenery.

A spacious living room with a white sofa, a wooden chair, a coffee table, and a large window with a view.

A room with a bed, a wooden partition, and a view through a window with shutters.

17. Casa Trujillo Cartagena

Cartagena Centro, 0.1 km from Santo Domingo Square

Gina

￥34,681

￥34,681 total

Oct 22 - Oct 23

A pool area with a spiral staircase, lounge chairs, and potted plants.

A restaurant with high arched windows, a chandelier, and neatly set dining tables.

An ornate wooden door with brass handles, a chandelier, and a table with potted plants.

An outdoor patio area with wooden furniture, umbrellas, and a pool.

18. Casa Pestagua Relais Châteaux

Cartagena Centro, < 0.1 km from Santo Domingo Square

Emil

￥91,422

￥91,422 total

Nov 18 - Nov 19

A hotel room with a large bed, a desk, a chair, and a balcony with a view of buildings.

A large, historic building with a central courtyard, surrounded by water and boats.

A two-story building with a white facade, large windows with blue shutters, and a wooden entrance door.

A modern hotel room with a large bed, a wooden wardrobe, a desk with a lamp, and a chair.

19. GHL Arsenal Hotel

Getsemani, 0.6 km from Santo Domingo Square

Shayna

￥19,810

￥19,810 total

Nov 18 - Nov 19

A dining table with a plate of food, a glass vase with flowers, and a woven placemat.

A person sitting by a window with a laptop and a bowl, overlooking a building and greenery.

A room with a stone wall, a sofa, a chair, a table with a candle, and hanging lights.

20. Casa Noa Colonial Rooms

Cartagena Centro, 0.3 km from Santo Domingo Square

Jose P

￥10,619

￥10,619 total

Oct 19 - Oct 20

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Compare popular hotels close to Santo Domingo Square

Property	Star rating	Guest rating
Casa Belle Cartagena Hotel Boutique	10.0 Exceptional 11 reviews	View
Hotel Quadrifolio	10.0 Exceptional 169 reviews	View
Casa La Merced by Mustique	10.0 Exceptional 37 reviews	View
Hotel Boutique Casona del Porvenir	9.8 Exceptional 103 reviews	View
Palacio del Agua by Faranda Boutique	9.8 Exceptional 127 reviews	View

Top Santo Domingo Square Hotel Reviews

Osh Hotel Cartagena

10/10 Excellent

"This place was awesome. Wish I satyed for more days. Only complaint is the breakfast included buffet. I didn't love it."

Hotel Casa La Mantilla by Faranda Boutique

10/10 Excellent

"Great spot - bit pricey when we went cause it was a holiday weekend, but cannot fault the hotel - the staff, the pool and the breakfast were all great. We struggled to get the right hot water temperature but it was so hot there it didn’t matter"

Hyatt Regency Cartagena

10/10 Excellent

"El mejor hotel en Cartagena! Agradecimiento a las siguientes personas. Isabella, Natalia, Fernanda Tedys, Yelvis. Piso 30. Una atención espectacular. Ya queremos regresar."

Four Seasons Hotel & Residences Cartagena

10/10 Excellent

"The hotel and staff were great."

Casa Noa Colonial Rooms

8/10 Good

"The room was perfect for a quick stay. Clean bed, nice location, the shower was odd cause it would not drain super fast (and that’s not how they are in the old city normally) so if you showered for longer than 5 mins it would flood the bathroom… but it’s okay. It was a nice stop for one night and we would do it again for a quick stay for sure."

Soy Local Centro Historico

8/10 Good

"Excelente servicio, limpieza y ubicacion."

Mood Matuna Hotel Cartagena

10/10 Excellent

"The staff were very friendly and helpful"

GHL Collection Armería Real Hotel

8/10 Good

"The room and property were spotless, and every staff member we met was attentive and kind. Breakfast had plenty of good options, and the pool was well kept with great sun for lounging. The room was a bit dark and the magnifying mirror needed replacing, but those were minor. I loved the clothesline in the bathroom, such a thoughtful touch!"

Hotel Casa San Agustin

10/10 Excellent

"The staff, facility and the whole experience was amazing. When you are inside the hotel property, the outside world is shut down and it feels like a sanctuary of its own. I enjoyed my experience."

Other attractions near Santo Domingo Square

Cartagena Cathedral

9.2/10 (3,019 reviews)

After visiting Cartagena Cathedral, make a plan to see the other sights and activities in Cartagena. Amble around the area's beautiful beaches or seek out the local tours.

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Templo de Santo Domingo

Templo de Santo Domingo is just one of the places to see in Cartagena, so why not enjoy the other things to explore during your travels? Stroll along the beautiful beaches or seek out the local tours.

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Botero's Mujer Reclinada

You can learn about the history of Cartagena with a stop at Botero's Mujer Reclinada. Stroll along the beautiful beaches or seek out the local tours.

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Santo Domingo Church and Monastery

After visiting Santo Domingo Church and Monastery, make a plan to see the other sights and activities in Cartagena. Stroll along the beautiful beaches or seek out the local tours.

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Iglesia de Santo Domingo

After visiting Iglesia de Santo Domingo, make a plan to see the other sights and activities in Cartagena. Stroll along the beautiful beaches or seek out the local tours.

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Palace of the Inquisition Cartagena Historical Museum

8.6/10 (69 reviews)

You can browse the exhibits at Palace of the Inquisition Cartagena Historical Museum, a museum with a story of its own, during your trip to Cartagena. Amble around the area's beautiful beaches or seek out the local tours.

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Bolivar Square

9.2/10 (2,207 reviews)

Find out about the history of Cartagena when you spend time at Bolivar Square. Amble around the area's beautiful beaches or seek out the local tours.

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Cathedral of Saint Catherine of Alexandria

After visiting Cathedral of Saint Catherine of Alexandria, make a plan to see the other sights and activities in Cartagena. Discover the area's top-notch restaurants or seek out the local tours.

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Frequently asked questions

What's the area like around Santo Domingo Square?

Santo Domingo Square is located in a historic area of Cartagena known for its beautiful beaches. If you're looking for a convenient place to stay, check out the 1200 hotels and other accommodations you'll find within a mile.

Where is the best place to stay near Santo Domingo Square?

Adjacent to Santo Domingo Square, Hotel Voilá Centro Histórico is one of the top choices for your stay based on our traveler data, and this hotel offers 2 outdoor pools and 2 bars. Other good choices within a short distance include Mood Matuna Hotel Cartagena and Osh Hotel Cartagena.

How many hotels can I expect to find close to Santo Domingo Square?

Expedia has 1200 hotels and other accommodations within a mile from Santo Domingo Square.

If I need to cancel the hotel reservation for my stay near Santo Domingo Square, will I receive a refund?

Yes! The majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the top deals on offer near Santo Domingo Square.

Where can I learn more about changing or cancelling my trip in the area near Santo Domingo Square?

To access more information about picking new dates or cancelling your stay near Santo Domingo Square, go to https://www.expedia.com/service/.

What can I see and do near Santo Domingo Square?

Study the collections at Palace of the Inquisition Cartagena Historical Museum, Palacio de la Inquisicion, or Cartagena's Gold Museum. Plaza Santo Domingo, San Pedro Claver Church and Convent, and Clock Tower are monuments to see when you're exploring the area around Santo Domingo Square. You can wander around Parque de La Marina, Centenary Park, or La Merced Square if you want a dose of fresh air.

Find hotels near Santo Domingo Square, Cartagena from ￥10,619

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Our top choices for Santo Domingo Square hotels

1. Casa Belle Cartagena Hotel Boutique

2. Hotel Quadrifolio

3. Casa La Merced by Mustique

4. Hotel Boutique Casona del Porvenir

5. Palacio del Agua by Faranda Boutique

6. Casa Claver Loft Boutique Hotel

7. Hotel Casa San Agustin

8. Hotel Casa Bianca By Faranda Boutique

9. Four Seasons Hotel & Residences Cartagena

10. Casa Carolina Luxury Wellness Hotel

11. Amarla Boutique Hotel Cartagena

12. Privado Designer Boutique Hotel

13. Cinco Quintas Hotel Boutique

14. Sophia Hotel By OxoHotel

15. Hotel Casa del Gobernador

16. Bastión Luxury Hotel

17. Casa Trujillo Cartagena

18. Casa Pestagua Relais Châteaux

19. GHL Arsenal Hotel

20. Casa Noa Colonial Rooms

Compare popular hotels close to Santo Domingo Square

Top Santo Domingo Square Hotel Reviews

Osh Hotel Cartagena

Hotel Casa La Mantilla by Faranda Boutique

Hyatt Regency Cartagena

Four Seasons Hotel & Residences Cartagena

Casa Noa Colonial Rooms

Soy Local Centro Historico

Mood Matuna Hotel Cartagena

GHL Collection Armería Real Hotel

Hotel Casa San Agustin

Other attractions near Santo Domingo Square

Cartagena Cathedral

Templo de Santo Domingo

Botero's Mujer Reclinada

Santo Domingo Church and Monastery

Iglesia de Santo Domingo

Palace of the Inquisition Cartagena Historical Museum

Bolivar Square

Cathedral of Saint Catherine of Alexandria

Frequently asked questions